Differential requirements for Th1 and Th17 responses to a systemic self-antigen.

Aquaporin 4-specific T cells in neuromyelitis optica exhibit a Th17 bias and recognize Clostridium ABC transporter. Ann Neurol (2012) 1.75

Immunological cell type characterization and Th1-Th17 cytokine production in a mouse model of Gaucher disease. Mol Genet Metab (2012) 0.85

IL-17A/F modulates fibrocyte functions in cooperation with CD40-mediated signaling. Inflammation (2013) 0.79

Isolation of human MHC class II-restricted T cell receptors from the autologous T-cell repertoire with potent anti-leukaemic reactivity. Immunology (2012) 0.77

Natural versus adaptive regulatory T cells. Nat Rev Immunol (2003) 8.74

Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo. J Exp Med (2003) 5.23

Interferon gamma is required for activation-induced death of T lymphocytes. J Exp Med (2002) 3.80

Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen. J Exp Med (2005) 3.70

The enemy within: keeping self-reactive T cells at bay in the periphery. Nat Rev Immunol (2002) 3.47

Response to self antigen imprints regulatory memory in tissues. Nature (2011) 2.96

T-cell costimulation--biology, therapeutic potential, and challenges. N Engl J Med (2006) 2.81

Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease. J Exp Med (2006) 2.46

Front-line treatment of acute promyelocytic leukemia with AIDA induction followed by risk-adapted consolidation for adults younger than 61 years: results of the AIDA-2000 trial of the GIMEMA Group. Blood (2010) 2.20

Regulatory T cells: recommendations to simplify the nomenclature. Nat Immunol (2013) 2.13

Interleukin-2 enhances CD4+ T cell memory by promoting the generation of IL-7R alpha-expressing cells. J Exp Med (2007) 1.99

Memory regulatory T cells reside in human skin. J Clin Invest (2014) 1.95

Regulatory T cells in the periphery. Immunol Rev (2006) 1.94

The initial phase of an immune response functions to activate regulatory T cells. J Immunol (2009) 1.88

Allogeneic compared with autologous stem cell transplantation in the treatment of patients younger than 46 years with acute myeloid leukemia (AML) in first complete remission (CR1): an intention-to-treat analysis of the EORTC/GIMEMAAML-10 trial. Blood (2003) 1.84

Interleukin-2 in the development and control of inflammatory disease. Immunol Rev (2008) 1.83

Paths to understanding the genetic basis of autoimmune disease. Nature (2005) 1.79

Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells. J Immunol (2010) 1.79

A resource for the conditional ablation of microRNAs in the mouse. Cell Rep (2012) 1.66

CD4+CD25+ cells controlling a pathogenic CD4 response inhibit cytokine differentiation, CXCR-3 expression, and tissue invasion. J Immunol (2004) 1.66

Ctla-4 controls regulatory T cell peripheral homeostasis and is required for suppression of pancreatic islet autoimmunity. J Immunol (2009) 1.66

Matrix metalloproteinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progression. Cancer Res (2010) 1.60

The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens. Nat Immunol (2003) 1.57

Induction therapy with idarubicin alone significantly influences event-free survival duration in patients with newly diagnosed hypergranular acute promyelocytic leukemia: final results of the GIMEMA randomized study LAP 0389 with 7 years of minimal follow-up. Blood (2002) 1.55

IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells. Proc Natl Acad Sci U S A (2012) 1.54

Cutting edge: the Th1 response inhibits the generation of peripheral regulatory T cells. J Immunol (2009) 1.52

Detection of minimal residual disease in peripheral blood stem cells from two acute myeloid leukemia patients with trisomy 8 predicts early relapse after autologous bone marrow transplantation. Cancer Genet Cytogenet (2002) 1.39

STAT1-activating cytokines limit Th17 responses through both T-bet-dependent and -independent mechanisms. J Immunol (2010) 1.33

Cutting Edge: memory regulatory t cells require IL-7 and not IL-2 for their maintenance in peripheral tissues. J Immunol (2013) 1.29

Cooperative roles of CTLA-4 and regulatory T cells in tolerance to an islet cell antigen. J Exp Med (2004) 1.23

Role of B7 in T cell tolerance. J Immunol (2004) 1.21

IL-2 induces a competitive survival advantage in T lymphocytes. J Immunol (2004) 1.20

CTLA-4 differentially regulates T cell responses to endogenous tissue protein versus exogenous immunogen. J Immunol (2002) 1.19

Functional and molecular comparison of anergic and regulatory T lymphocytes. J Immunol (2006) 1.17

Treating human autoimmunity: current practice and future prospects. Sci Transl Med (2012) 1.16

Control of CD4+ T-cell memory by cytokines and costimulators. Immunol Rev (2006) 1.14

The link between lymphocyte deficiency and autoimmunity: roles of endogenous T and B lymphocytes in tolerance. J Immunol (2005) 1.12

Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation. Nat Immunol (2004) 1.08

Posttranscriptional silencing of effector cytokine mRNA underlies the anergic phenotype of self-reactive T cells. Immunity (2011) 1.07

CD28 signals in the immature immunological synapse. J Immunol (2004) 1.06

T-cell tolerance and autoimmunity to systemic and tissue-restricted self-antigens. Immunol Rev (2005) 1.06

Duration of antigen receptor signaling determines T-cell tolerance or activation. Proc Natl Acad Sci U S A (2010) 1.05

B7-independent inhibition of T cells by CTLA-4. J Immunol (2005) 1.05

Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist. J Clin Invest (2006) 1.05

Distinct roles of helper T-cell subsets in a systemic autoimmune disease. Blood (2008) 1.04

Decreased hepatic futile cycling compensates for increased glucose disposal in the Pten heterodeficient mouse. Diabetes (2006) 1.01

Promotion and prevention of autoimmune disease by CD8+ T cells. J Autoimmun (2013) 0.97

Cutting edge: contributions of apoptosis and anergy to systemic T cell tolerance. J Immunol (2008) 0.94

Targeting T cell-specific costimulators and growth factors in a model of autoimmune hemolytic anemia. J Immunol (2007) 0.94

High-dose sequential chemotherapy and peripheral blood progenitor cell autografting in patients with refractory and/or recurrent Hodgkin lymphoma: a multicenter study of the intergruppo Italiano Linfomi showing prolonged disease free survival in patients treated at first recurrence. Cancer (2003) 0.93

Cutting edge: Self-antigen controls the balance between effector and regulatory T cells in peripheral tissues. J Immunol (2014) 0.92

Constitutive expression of B7-1 on B cells uncovers autoimmunity toward the B cell compartment in the nonobese diabetic mouse. J Immunol (2007) 0.91

Role of T cells in a murine model of Escherichia coli sepsis. Eur J Immunol (2007) 0.91

MDR1 protein expression is an independent predictor of complete remission in newly diagnosed adult acute lymphoblastic leukemia. Blood (2002) 0.91

The life of regulatory T cells. Ann N Y Acad Sci (2013) 0.88

Mechanisms of human autoimmunity. J Clin Invest (2015) 0.87

Revisiting the role of IL-2 in autoimmunity. Eur J Immunol (2010) 0.87

Balance of Th1 and Th17 effector and peripheral regulatory T cells. Microbes Infect (2009) 0.87

Dysregulated TCL1 requires the germinal center and genome instability for mature B-cell transformation. Blood (2006) 0.86

A large-scale study of bone marrow involvement in patients with Hodgkin's lymphoma. Clin Lymphoma (2004) 0.85

High dose sequential chemotherapy with autologous transplantation versus dose-dense chemotherapy MegaCEOP as first line treatment in poor-prognosis diffuse large cell lymphoma: an "Intergruppo Italiano Linfomi" randomized trial. Haematologica (2005) 0.85

Opposing functions of IL-2 and IL-7 in the regulation of immune responses. Cytokine (2011) 0.82

Life and death in effector T cells. Nat Immunol (2002) 0.82

Transdifferentiation and nuclear reprogramming in hematopoietic development and neoplasia. Immunol Rev (2002) 0.79

A single-chain-variable-fragment fluorescence biosensor activates fluorogens from dissimilar chemical families. Protein Pept Lett (2014) 0.77

Retraction. Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death. Immunity (2009) 0.77

Dendritic cells giveth and taketh away. Nat Immunol (2005) 0.77

Spontaneous autoimmunity in the absence of IL-2 is driven by uncontrolled dendritic cells. J Immunol (2012) 0.75

Functional tolerance is maintained despite proliferation of CD4 T cells after encounter with tissue-derived antigen. Dev Immunol (2002) 0.75

A network of regulatory pathways in lepromatous leprosy. Clin Immunol (2011) 0.75

Pillars article: antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors. 1984. J Immunol (2007) 0.75

Retraction. The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens. Immunity (2009) 0.75

Retraction. Autoimmunity as a consequence of retrovirus-mediated expression of C-FLIP in lymphocytes. Immunity (2009) 0.75

Novel Biosensor of Membrane Protein Proximity Based on Fluorogen Activated Proteins. Comb Chem High Throughput Screen (2016) 0.75