Published in J Am Chem Soc on September 11, 2002
Fluorescent sensors for measuring metal ions in living systems. Chem Rev (2014) 1.71
A tautomeric zinc sensor for ratiometric fluorescence imaging: application to nitric oxide-induced release of intracellular zinc. Proc Natl Acad Sci U S A (2004) 1.27
QZ1 and QZ2: rapid, reversible quinoline-derivatized fluoresceins for sensing biological Zn(II). J Am Chem Soc (2005) 1.14
Visualizing metal ions in cells: an overview of analytical techniques, approaches, and probes. Biochim Biophys Acta (2012) 1.10
Small molecule-based ratiometric fluorescence probes for cations, anions, and biomolecules. Chem Soc Rev (2014) 1.07
Imaging beyond the proteome. Chem Commun (Camb) (2012) 0.95
Sensing metal ions with DNA building blocks: fluorescent pyridobenzimidazole nucleosides. J Am Chem Soc (2006) 0.93
Computational studies on response and binding selectivity of fluorescence sensors. J Phys Chem B (2010) 0.89
Midrange affinity fluorescent Zn(II) sensors of the Zinpyr family: syntheses, characterization, and biological imaging applications. Inorg Chem (2006) 0.89
Phosphorescent sensor for biological mobile zinc. J Am Chem Soc (2011) 0.85
A macrocyclic zinc(II) fluorophore as a detector of apoptosis. Proc Natl Acad Sci U S A (2003) 0.84
Zn(II)-coordination modulated ligand photophysical processes - the development of fluorescent indicators for imaging biological Zn(II) ions. RSC Adv (2014) 0.83
Development of fluorescent probes for bioimaging applications. Proc Jpn Acad Ser B Phys Biol Sci (2010) 0.82
Balance between fluorescence enhancement and association affinity in fluorescent heteroditopic indicators for imaging zinc ion in living cells. Inorg Chem (2011) 0.81
Dual-modal magnetic resonance/fluorescent zinc probes for pancreatic β-cell mass imaging. Chemistry (2015) 0.77
Alzheimer's disease imaging with a novel Tau targeted near infrared ratiometric probe. Am J Nucl Med Mol Imaging (2013) 0.75
Self-assembled hydrophobin for producing water-soluble and membrane permeable fluorescent dye. Sci Rep (2016) 0.75
Highly selective fluorescent chemosensor for Zn2+ derived from inorganic-organic hybrid magnetic core/shell Fe3O4@SiO2 nanoparticles. Nanoscale Res Lett (2012) 0.75
Rapid cancer detection by topically spraying a γ-glutamyltranspeptidase-activated fluorescent probe. Sci Transl Med (2011) 4.72
Development of novel fluorescence probes that can reliably detect reactive oxygen species and distinguish specific species. J Biol Chem (2002) 4.54
New strategies for fluorescent probe design in medical diagnostic imaging. Chem Rev (2010) 3.35
Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes. Nat Med (2008) 3.15
A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity. Nature (2013) 2.74
Simultaneous multicolor imaging of five different lymphatic basins using quantum dots. Nano Lett (2007) 2.46
Evolution of fluorescein as a platform for finely tunable fluorescence probes. J Am Chem Soc (2005) 2.35
Highly sensitive fluorescence probes for nitric oxide based on boron dipyrromethene chromophore-rational design of potentially useful bioimaging fluorescence probe. J Am Chem Soc (2004) 2.12
In vivo diagnosis of epidermal growth factor receptor expression using molecular imaging with a cocktail of optically labeled monoclonal antibodies. Clin Cancer Res (2007) 2.01
Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate. J Biol Chem (2005) 1.95
Active oxygen species generated from photoexcited fullerene (C60) as potential medicines: O2-* versus 1O2. J Am Chem Soc (2003) 1.87
AMP-activated protein kinase inhibits angiotensin II-stimulated vascular smooth muscle cell proliferation. Circulation (2004) 1.85
Zinc sensing for cellular application. Curr Opin Chem Biol (2004) 1.77
Spectral fluorescence molecular imaging of lung metastases targeting HER2/neu. Clin Cancer Res (2007) 1.76
Mechanistic background and clinical applications of indocyanine green fluorescence imaging of hepatocellular carcinoma. Ann Surg Oncol (2013) 1.76
Multimodal nanoprobes for radionuclide and five-color near-infrared optical lymphatic imaging. ACS Nano (2007) 1.70
Dynamic visualization of RANKL and Th17-mediated osteoclast function. J Clin Invest (2013) 1.68
A target cell-specific activatable fluorescence probe for in vivo molecular imaging of cancer based on a self-quenched avidin-rhodamine conjugate. Cancer Res (2007) 1.64
An enzymatically activated fluorescence probe for targeted tumor imaging. J Am Chem Soc (2007) 1.46
Improvement and biological applications of fluorescent probes for zinc, ZnAFs. J Am Chem Soc (2002) 1.43
Development of a highly selective fluorescence probe for hydrogen sulfide. J Am Chem Soc (2011) 1.43
Fluorophore-quencher based activatable targeted optical probes for detecting in vivo cancer metastases. Mol Pharm (2009) 1.42
Highly sensitive near-infrared fluorescent probes for nitric oxide and their application to isolated organs. J Am Chem Soc (2005) 1.41
Adipose-derived stem cells stimulate reendothelialization in stented rat abdominal aorta. Circ J (2014) 1.40
Phosphatidylinositol 4-kinase III beta is a target of enviroxime-like compounds for antipoliovirus activity. J Virol (2010) 1.40
Evolution of group 14 rhodamines as platforms for near-infrared fluorescence probes utilizing photoinduced electron transfer. ACS Chem Biol (2011) 1.38
A self-quenched galactosamine-serum albumin-rhodamineX conjugate: a "smart" fluorescent molecular imaging probe synthesized with clinically applicable material for detecting peritoneal ovarian cancer metastases. Clin Cancer Res (2007) 1.38
Activatable fluorescent molecular imaging of peritoneal metastases following pretargeting with a biotinylated monoclonal antibody. Cancer Res (2007) 1.37
Development of a ratiometric fluorescent zinc ion probe in near-infrared region, based on tricarbocyanine chromophore. J Am Chem Soc (2006) 1.36
Fluorescent probes for sensing and imaging. Nat Methods (2011) 1.32
D-galactose receptor-targeted in vivo spectral fluorescence imaging of peritoneal metastasis using galactosamin-conjugated serum albumin-rhodamine green. J Biomed Opt (2007) 1.29
A photocleavable rapamycin conjugate for spatiotemporal control of small GTPase activity. J Am Chem Soc (2010) 1.29
Rational principles for modulating fluorescence properties of fluorescein. J Am Chem Soc (2004) 1.26
Highly efficient and photostable photosensitizer based on BODIPY chromophore. J Am Chem Soc (2005) 1.25
Design and synthesis of a novel magnetic resonance imaging contrast agent for selective sensing of zinc ion. Chem Biol (2002) 1.23
Simultaneous two-color spectral fluorescence lymphangiography with near infrared quantum dots to map two lymphatic flows from the breast and the upper extremity. Breast Cancer Res Treat (2006) 1.23
Mossy fiber Zn2+ spillover modulates heterosynaptic N-methyl-D-aspartate receptor activity in hippocampal CA3 circuits. J Cell Biol (2002) 1.23
Two-color lymphatic mapping using Ig-conjugated near infrared optical probes. J Invest Dermatol (2007) 1.22
Rational design principle for modulating fluorescence properties of fluorescein-based probes by photoinduced electron transfer. J Am Chem Soc (2003) 1.22
Paramagnetic relaxation-based 19f MRI probe to detect protease activity. J Am Chem Soc (2007) 1.21
A comparison of the emission efficiency of four common green fluorescence dyes after internalization into cancer cells. Bioconjug Chem (2006) 1.20
Insights into Zn2+ homeostasis in neurons from experimental and modeling studies. Am J Physiol Cell Physiol (2008) 1.20
Angiotensin II and tumor necrosis factor-alpha synergistically promote monocyte chemoattractant protein-1 expression: roles of NF-kappaB, p38, and reactive oxygen species. Am J Physiol Heart Circ Physiol (2008) 1.19
Development and application of a near-infrared fluorescence probe for oxidative stress based on differential reactivity of linked cyanine dyes. J Am Chem Soc (2010) 1.18
Fluorescent probes for bioimaging applications. Curr Opin Chem Biol (2008) 1.18
Mechanism-based molecular design of highly selective fluorescence probes for nitrative stress. J Am Chem Soc (2006) 1.18
Development of a highly specific rhodamine-based fluorescence probe for hypochlorous acid and its application to real-time imaging of phagocytosis. J Am Chem Soc (2007) 1.16
Multicolor imaging of lymphatic function with two nanomaterials: quantum dot-labeled cancer cells and dendrimer-based optical agents. Nanomedicine (Lond) (2009) 1.15
Nonspecific medium effects versus specific group positioning in the antibody and albumin catalysis of the base-promoted ring-opening reactions of benzisoxazoles. J Am Chem Soc (2004) 1.15
Selective zinc sensor molecules with various affinities for Zn2+, revealing dynamics and regional distribution of synaptically released Zn2+ in hippocampal slices. J Am Chem Soc (2005) 1.15
Design and synthesis of fluorescent probes for selective detection of highly reactive oxygen species in mitochondria of living cells. J Am Chem Soc (2007) 1.14
Development of an iminocoumarin-based zinc sensor suitable for ratiometric fluorescence imaging of neuronal zinc. J Am Chem Soc (2007) 1.14
Highly activatable and rapidly releasable caged fluorescein derivatives. J Am Chem Soc (2007) 1.12
Hypoxia-sensitive fluorescent probes for in vivo real-time fluorescence imaging of acute ischemia. J Am Chem Soc (2010) 1.10
Blockade of inflammatory responses by a small-molecule inhibitor of the Rac activator DOCK2. Chem Biol (2012) 1.09
Design and synthesis of a library of BODIPY-based environmental polarity sensors utilizing photoinduced electron-transfer-controlled fluorescence ON/OFF switching. J Am Chem Soc (2007) 1.08
Red fluorescent probe for monitoring the dynamics of cytoplasmic calcium ions. Angew Chem Int Ed Engl (2013) 1.08
Tunable design strategy for fluorescence probes based on 4-substituted BODIPY chromophore: improvement of highly sensitive fluorescence probe for nitric oxide. Anal Bioanal Chem (2006) 1.07
Fluorescence endoscopic detection of murine colitis-associated colon cancer by topically applied enzymatically rapid-activatable probe. Gut (2012) 1.07
Development of a far-red to near-infrared fluorescence probe for calcium ion and its application to multicolor neuronal imaging. J Am Chem Soc (2011) 1.06
Adipose tissue-derived stem cells inhibit neointimal formation in a paracrine fashion in rat femoral artery. Am J Physiol Heart Circ Physiol (2009) 1.05
Targeted optical imaging of cancer cells using lectin-binding BODIPY conjugated avidin. Biochem Biophys Res Commun (2006) 1.05
In vivo spectral fluorescence imaging of submillimeter peritoneal cancer implants using a lectin-targeted optical agent. Neoplasia (2006) 1.04
BODIPY-based probes for the fluorescence imaging of biomolecules in living cells. Chem Soc Rev (2015) 1.04
Time-resolved long-lived luminescence imaging method employing luminescent lanthanide probes with a new microscopy system. J Am Chem Soc (2007) 1.03
Development of an Si-rhodamine-based far-red to near-infrared fluorescence probe selective for hypochlorous acid and its applications for biological imaging. J Am Chem Soc (2011) 1.03
A simple and effective strategy to increase the sensitivity of fluorescence probes in living cells. J Am Chem Soc (2009) 1.03