Published in J Am Chem Soc on March 03, 2010
A palette of fluorescent probes with varying emission colors for imaging hydrogen peroxide signaling in living cells. J Am Chem Soc (2010) 1.79
Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing. Nat Biotechnol (2014) 1.72
Semiconducting polymer nanoparticles as photoacoustic molecular imaging probes in living mice. Nat Nanotechnol (2014) 1.64
Semiconducting polymer nanoprobe for in vivo imaging of reactive oxygen and nitrogen species. Angew Chem Int Ed Engl (2013) 1.02
Defining a polymethine dye for fluorescence anisotropy applications in the near-infrared spectral range. Chemphyschem (2012) 0.97
Optical modulation and selective recovery of Cy5 fluorescence. Chemphyschem (2011) 0.94
Minimization of self-quenching fluorescence on dyes conjugated to biomolecules with multiple labeling sites via asymmetrically charged NIR fluorophores. Contrast Media Mol Imaging (2014) 0.84
Exploiting oxidative microenvironments in the body as triggers for drug delivery systems. Antioxid Redox Signal (2014) 0.83
Reactive Species Involved in the Regioselective Photooxidation of Heptamethine Cyanines. Chem Sci (2015) 0.83
Development of fluorescent probes for bioimaging applications. Proc Jpn Acad Ser B Phys Biol Sci (2010) 0.82
Recent advances of semiconducting polymer nanoparticles in in vivo molecular imaging. J Control Release (2016) 0.81
Functional fluorescently labeled bithiazole ΔF508-CFTR corrector imaged in whole body slices in mice. Bioconjug Chem (2011) 0.80
In vivo retinal and choroidal hypoxia imaging using a novel activatable hypoxia-selective near-infrared fluorescent probe. Graefes Arch Clin Exp Ophthalmol (2016) 0.77
FRET-based system for probing protein-protein interactions between σR and RsrA from Streptomyces coelicolor in response to the redox environment. PLoS One (2014) 0.76
A fluorescent peroxidase probe increases the sensitivity of commercial ELISAs by two orders of magnitude. Chem Commun (Camb) (2013) 0.75
Mutually-Reactive, Fluorogenic Hydrocyanine/Quinone Reporter Pairs for In-Solution Biosensing via Nanodroplet Association. ACS Appl Mater Interfaces (2015) 0.75
Imaging Reactive Oxygen Species-Induced Modifications in Living Systems. Antioxid Redox Signal (2016) 0.75
Preventing Radiobleaching of Cyanine Fluorophores Enhances Stability of Nuclear/NIRF Multimodality Imaging Agents. Theranostics (2017) 0.75
Sensitive detection of ozone by a practical resorufin-based spectroscopic probe with extremely low background signal. Sci Rep (2013) 0.75
A multi-signal fluorescent probe for simultaneously distinguishing and sequentially sensing cysteine/homocysteine, glutathione, and hydrogen sulfide in living cells. Chem Sci (2017) 0.75
Resolvin E1 and protectin D1 activate inflammation-resolution programmes. Nature (2007) 6.53
Rapid cancer detection by topically spraying a γ-glutamyltranspeptidase-activated fluorescent probe. Sci Transl Med (2011) 4.72
Development of novel fluorescence probes that can reliably detect reactive oxygen species and distinguish specific species. J Biol Chem (2002) 4.54
Molecular circuits of resolution: formation and actions of resolvins and protectins. J Immunol (2005) 4.30
New strategies for fluorescent probe design in medical diagnostic imaging. Chem Rev (2010) 3.35
The lipid mediator protectin D1 inhibits influenza virus replication and improves severe influenza. Cell (2013) 3.19
Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes. Nat Med (2008) 3.15
A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity. Nature (2013) 2.74
Simultaneous multicolor imaging of five different lymphatic basins using quantum dots. Nano Lett (2007) 2.46
Resolvin E2: identification and anti-inflammatory actions: pivotal role of human 5-lipoxygenase in resolvin E series biosynthesis. Chem Biol (2006) 2.36
Evolution of fluorescein as a platform for finely tunable fluorescence probes. J Am Chem Soc (2005) 2.35
Highly sensitive fluorescence probes for nitric oxide based on boron dipyrromethene chromophore-rational design of potentially useful bioimaging fluorescence probe. J Am Chem Soc (2004) 2.12
In vivo diagnosis of epidermal growth factor receptor expression using molecular imaging with a cocktail of optically labeled monoclonal antibodies. Clin Cancer Res (2007) 2.01
Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate. J Biol Chem (2005) 1.95
Active oxygen species generated from photoexcited fullerene (C60) as potential medicines: O2-* versus 1O2. J Am Chem Soc (2003) 1.87
AMP-activated protein kinase inhibits angiotensin II-stimulated vascular smooth muscle cell proliferation. Circulation (2004) 1.85
Zinc sensing for cellular application. Curr Opin Chem Biol (2004) 1.77
Spectral fluorescence molecular imaging of lung metastases targeting HER2/neu. Clin Cancer Res (2007) 1.76
Mechanistic background and clinical applications of indocyanine green fluorescence imaging of hepatocellular carcinoma. Ann Surg Oncol (2013) 1.76
Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their aspirin-triggered endogenous epimers: an overview of their protective roles in catabasis. Prostaglandins Other Lipid Mediat (2004) 1.75
The anti-inflammatory and proresolving mediator resolvin E1 protects mice from bacterial pneumonia and acute lung injury. J Immunol (2009) 1.71
Multimodal nanoprobes for radionuclide and five-color near-infrared optical lymphatic imaging. ACS Nano (2007) 1.70
Resolvin E1 promotes mucosal surface clearance of neutrophils: a new paradigm for inflammatory resolution. FASEB J (2007) 1.67
Resolvin E1, an EPA-derived mediator in whole blood, selectively counterregulates leukocytes and platelets. Blood (2008) 1.66
A target cell-specific activatable fluorescence probe for in vivo molecular imaging of cancer based on a self-quenched avidin-rhodamine conjugate. Cancer Res (2007) 1.64
Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirin-triggered epimers. Lipids (2004) 1.57
Aspirin-triggered lipoxin A4 and B4 analogs block extracellular signal-regulated kinase-dependent TNF-alpha secretion from human T cells. J Immunol (2003) 1.52
Resolvin E1 receptor activation signals phosphorylation and phagocytosis. J Biol Chem (2009) 1.50
The arachidonic acid metabolome serves as a conserved regulator of cholesterol metabolism. Cell Metab (2014) 1.47
An enzymatically activated fluorescence probe for targeted tumor imaging. J Am Chem Soc (2007) 1.46
Improvement and biological applications of fluorescent probes for zinc, ZnAFs. J Am Chem Soc (2002) 1.43
Development of a highly selective fluorescence probe for hydrogen sulfide. J Am Chem Soc (2011) 1.43
Fluorophore-quencher based activatable targeted optical probes for detecting in vivo cancer metastases. Mol Pharm (2009) 1.42
Anti-angiogenesis effect of the novel anti-inflammatory and pro-resolving lipid mediators. Invest Ophthalmol Vis Sci (2009) 1.42
Combination therapy of 15-epi-lipoxin A4 with antibiotics protects mice from Escherichia coli-induced sepsis*. Crit Care Med (2014) 1.42
Highly sensitive near-infrared fluorescent probes for nitric oxide and their application to isolated organs. J Am Chem Soc (2005) 1.41
Adipose-derived stem cells stimulate reendothelialization in stented rat abdominal aorta. Circ J (2014) 1.40
Phosphatidylinositol 4-kinase III beta is a target of enviroxime-like compounds for antipoliovirus activity. J Virol (2010) 1.40
Anti-inflammatory circuitry: lipoxin, aspirin-triggered lipoxins and their receptor ALX. Prostaglandins Leukot Essent Fatty Acids (2005) 1.39
Evolution of group 14 rhodamines as platforms for near-infrared fluorescence probes utilizing photoinduced electron transfer. ACS Chem Biol (2011) 1.38
A self-quenched galactosamine-serum albumin-rhodamineX conjugate: a "smart" fluorescent molecular imaging probe synthesized with clinically applicable material for detecting peritoneal ovarian cancer metastases. Clin Cancer Res (2007) 1.38
Activatable fluorescent molecular imaging of peritoneal metastases following pretargeting with a biotinylated monoclonal antibody. Cancer Res (2007) 1.37
Development of a ratiometric fluorescent zinc ion probe in near-infrared region, based on tricarbocyanine chromophore. J Am Chem Soc (2006) 1.36
Fluorescent probes for sensing and imaging. Nat Methods (2011) 1.32
Leukotriene B4 and lipoxin A4 are regulatory signals for neural stem cell proliferation and differentiation. FASEB J (2006) 1.31
Human ALX receptor regulates neutrophil recruitment in transgenic mice: roles in inflammation and host defense. FASEB J (2003) 1.29
D-galactose receptor-targeted in vivo spectral fluorescence imaging of peritoneal metastasis using galactosamin-conjugated serum albumin-rhodamine green. J Biomed Opt (2007) 1.29
A photocleavable rapamycin conjugate for spatiotemporal control of small GTPase activity. J Am Chem Soc (2010) 1.29
Rational principles for modulating fluorescence properties of fluorescein. J Am Chem Soc (2004) 1.26
Neuroprotectin D1/protectin D1 stereoselective and specific binding with human retinal pigment epithelial cells and neutrophils. Prostaglandins Leukot Essent Fatty Acids (2010) 1.26
Highly efficient and photostable photosensitizer based on BODIPY chromophore. J Am Chem Soc (2005) 1.25
Design and synthesis of a novel magnetic resonance imaging contrast agent for selective sensing of zinc ion. Chem Biol (2002) 1.23
Simultaneous two-color spectral fluorescence lymphangiography with near infrared quantum dots to map two lymphatic flows from the breast and the upper extremity. Breast Cancer Res Treat (2006) 1.23
Mossy fiber Zn2+ spillover modulates heterosynaptic N-methyl-D-aspartate receptor activity in hippocampal CA3 circuits. J Cell Biol (2002) 1.23
Eosinophils promote resolution of acute peritonitis by producing proresolving mediators in mice. FASEB J (2010) 1.22
Rational design principle for modulating fluorescence properties of fluorescein-based probes by photoinduced electron transfer. J Am Chem Soc (2003) 1.22
Two-color lymphatic mapping using Ig-conjugated near infrared optical probes. J Invest Dermatol (2007) 1.22
A comparison of the emission efficiency of four common green fluorescence dyes after internalization into cancer cells. Bioconjug Chem (2006) 1.20
Identification and structure determination of novel anti-inflammatory mediator resolvin E3, 17,18-dihydroxyeicosapentaenoic acid. J Biol Chem (2012) 1.19
Angiotensin II and tumor necrosis factor-alpha synergistically promote monocyte chemoattractant protein-1 expression: roles of NF-kappaB, p38, and reactive oxygen species. Am J Physiol Heart Circ Physiol (2008) 1.19
Fluorescent probes for bioimaging applications. Curr Opin Chem Biol (2008) 1.18
Mechanism-based molecular design of highly selective fluorescence probes for nitrative stress. J Am Chem Soc (2006) 1.18
Prevention of ventricular fibrillation by cilostazol, an oral phosphodiesterase inhibitor, in a patient with Brugada syndrome. J Cardiovasc Electrophysiol (2002) 1.17
Development of a highly specific rhodamine-based fluorescence probe for hypochlorous acid and its application to real-time imaging of phagocytosis. J Am Chem Soc (2007) 1.16
Multicolor imaging of lymphatic function with two nanomaterials: quantum dot-labeled cancer cells and dendrimer-based optical agents. Nanomedicine (Lond) (2009) 1.15
Selective zinc sensor molecules with various affinities for Zn2+, revealing dynamics and regional distribution of synaptically released Zn2+ in hippocampal slices. J Am Chem Soc (2005) 1.15
Design and synthesis of fluorescent probes for selective detection of highly reactive oxygen species in mitochondria of living cells. J Am Chem Soc (2007) 1.14
Development of an iminocoumarin-based zinc sensor suitable for ratiometric fluorescence imaging of neuronal zinc. J Am Chem Soc (2007) 1.14
Candida albicans modulates host defense by biosynthesizing the pro-resolving mediator resolvin E1. PLoS One (2007) 1.13