Published in J Am Chem Soc on April 11, 2007
Rational chemical design of the next generation of molecular imaging probes based on physics and biology: mixing modalities, colors and signals. Chem Soc Rev (2011) 1.36
Monitoring protein interactions and dynamics with solvatochromic fluorophores. Trends Biotechnol (2009) 1.10
Differential tuning of the electron transfer parameters in 1,3,5-triarylpyrazolines: a rational design approach for optimizing the contrast ratio of fluorescent probes. J Am Chem Soc (2008) 1.08
Functionalized BF(2) Chelated Azadipyrromethene Dyes. Tetrahedron (2008) 0.98
CalFluors: A Universal Motif for Fluorogenic Azide Probes across the Visible Spectrum. J Am Chem Soc (2015) 0.98
Zn(II)-coordination modulated ligand photophysical processes - the development of fluorescent indicators for imaging biological Zn(II) ions. RSC Adv (2014) 0.83
Development of fluorescent probes for bioimaging applications. Proc Jpn Acad Ser B Phys Biol Sci (2010) 0.82
Controlling the diameter, monodispersity, and solubility of ApoA1 nanolipoprotein particles using telodendrimer chemistry. Protein Sci (2013) 0.80
Quantitatively mapping cellular viscosity with detailed organelle information via a designed PET fluorescent probe. Sci Rep (2014) 0.80
Fluorescent proton sensors based on energy transfer. J Org Chem (2011) 0.78
Deep-red emissive BODIPY-chlorin arrays excitable with green and red wavelengths. J Org Chem (2015) 0.77
Cell-free production of a functional oligomeric form of a chlamydia major outer membrane protein (MOMP) for vaccine development. J Biol Chem (2017) 0.76
Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue. Nat Commun (2016) 0.76
A highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutase. Chem Commun (Camb) (2016) 0.76
The Mechanisms and Biomedical Applications of an NIR BODIPY-Based Switchable Fluorescent Probe. Int J Mol Sci (2017) 0.75
Synthesis and characterization of BODIPY-alpha-tocopherol: a fluorescent form of vitamin E. J Org Chem (2010) 0.75
Interaction of BODIPY dyes with bovine serum albumin: a case study on the aggregation of a click-BODIPY dye. Phys Chem Chem Phys (2016) 0.75
d-PET-controlled "off-on" Polarity-sensitive Probes for Reporting Local Hydrophilicity within Lysosomes. Sci Rep (2016) 0.75
Rapid cancer detection by topically spraying a γ-glutamyltranspeptidase-activated fluorescent probe. Sci Transl Med (2011) 4.72
Development of novel fluorescence probes that can reliably detect reactive oxygen species and distinguish specific species. J Biol Chem (2002) 4.54
New strategies for fluorescent probe design in medical diagnostic imaging. Chem Rev (2010) 3.35
Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes. Nat Med (2008) 3.15
A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity. Nature (2013) 2.74
Simultaneous multicolor imaging of five different lymphatic basins using quantum dots. Nano Lett (2007) 2.46
Evolution of fluorescein as a platform for finely tunable fluorescence probes. J Am Chem Soc (2005) 2.35
Highly sensitive fluorescence probes for nitric oxide based on boron dipyrromethene chromophore-rational design of potentially useful bioimaging fluorescence probe. J Am Chem Soc (2004) 2.12
In vivo diagnosis of epidermal growth factor receptor expression using molecular imaging with a cocktail of optically labeled monoclonal antibodies. Clin Cancer Res (2007) 2.01
Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate. J Biol Chem (2005) 1.95
Active oxygen species generated from photoexcited fullerene (C60) as potential medicines: O2-* versus 1O2. J Am Chem Soc (2003) 1.87
AMP-activated protein kinase inhibits angiotensin II-stimulated vascular smooth muscle cell proliferation. Circulation (2004) 1.85
Zinc sensing for cellular application. Curr Opin Chem Biol (2004) 1.77
Spectral fluorescence molecular imaging of lung metastases targeting HER2/neu. Clin Cancer Res (2007) 1.76
Mechanistic background and clinical applications of indocyanine green fluorescence imaging of hepatocellular carcinoma. Ann Surg Oncol (2013) 1.76
Multimodal nanoprobes for radionuclide and five-color near-infrared optical lymphatic imaging. ACS Nano (2007) 1.70
A target cell-specific activatable fluorescence probe for in vivo molecular imaging of cancer based on a self-quenched avidin-rhodamine conjugate. Cancer Res (2007) 1.64
An enzymatically activated fluorescence probe for targeted tumor imaging. J Am Chem Soc (2007) 1.46
Improvement and biological applications of fluorescent probes for zinc, ZnAFs. J Am Chem Soc (2002) 1.43
Development of a highly selective fluorescence probe for hydrogen sulfide. J Am Chem Soc (2011) 1.43
Fluorophore-quencher based activatable targeted optical probes for detecting in vivo cancer metastases. Mol Pharm (2009) 1.42
Highly sensitive near-infrared fluorescent probes for nitric oxide and their application to isolated organs. J Am Chem Soc (2005) 1.41
Adipose-derived stem cells stimulate reendothelialization in stented rat abdominal aorta. Circ J (2014) 1.40
Phosphatidylinositol 4-kinase III beta is a target of enviroxime-like compounds for antipoliovirus activity. J Virol (2010) 1.40
Evolution of group 14 rhodamines as platforms for near-infrared fluorescence probes utilizing photoinduced electron transfer. ACS Chem Biol (2011) 1.38
A self-quenched galactosamine-serum albumin-rhodamineX conjugate: a "smart" fluorescent molecular imaging probe synthesized with clinically applicable material for detecting peritoneal ovarian cancer metastases. Clin Cancer Res (2007) 1.38
Activatable fluorescent molecular imaging of peritoneal metastases following pretargeting with a biotinylated monoclonal antibody. Cancer Res (2007) 1.37
Development of a ratiometric fluorescent zinc ion probe in near-infrared region, based on tricarbocyanine chromophore. J Am Chem Soc (2006) 1.36
Fluorescent probes for sensing and imaging. Nat Methods (2011) 1.32
D-galactose receptor-targeted in vivo spectral fluorescence imaging of peritoneal metastasis using galactosamin-conjugated serum albumin-rhodamine green. J Biomed Opt (2007) 1.29
A photocleavable rapamycin conjugate for spatiotemporal control of small GTPase activity. J Am Chem Soc (2010) 1.29
Rational principles for modulating fluorescence properties of fluorescein. J Am Chem Soc (2004) 1.26
Highly efficient and photostable photosensitizer based on BODIPY chromophore. J Am Chem Soc (2005) 1.25
Design and synthesis of a novel magnetic resonance imaging contrast agent for selective sensing of zinc ion. Chem Biol (2002) 1.23
Simultaneous two-color spectral fluorescence lymphangiography with near infrared quantum dots to map two lymphatic flows from the breast and the upper extremity. Breast Cancer Res Treat (2006) 1.23
Mossy fiber Zn2+ spillover modulates heterosynaptic N-methyl-D-aspartate receptor activity in hippocampal CA3 circuits. J Cell Biol (2002) 1.23
Two-color lymphatic mapping using Ig-conjugated near infrared optical probes. J Invest Dermatol (2007) 1.22
Rational design principle for modulating fluorescence properties of fluorescein-based probes by photoinduced electron transfer. J Am Chem Soc (2003) 1.22
A comparison of the emission efficiency of four common green fluorescence dyes after internalization into cancer cells. Bioconjug Chem (2006) 1.20
Angiotensin II and tumor necrosis factor-alpha synergistically promote monocyte chemoattractant protein-1 expression: roles of NF-kappaB, p38, and reactive oxygen species. Am J Physiol Heart Circ Physiol (2008) 1.19
Development and application of a near-infrared fluorescence probe for oxidative stress based on differential reactivity of linked cyanine dyes. J Am Chem Soc (2010) 1.18
Fluorescent probes for bioimaging applications. Curr Opin Chem Biol (2008) 1.18
Mechanism-based molecular design of highly selective fluorescence probes for nitrative stress. J Am Chem Soc (2006) 1.18
Development of a highly specific rhodamine-based fluorescence probe for hypochlorous acid and its application to real-time imaging of phagocytosis. J Am Chem Soc (2007) 1.16
Multicolor imaging of lymphatic function with two nanomaterials: quantum dot-labeled cancer cells and dendrimer-based optical agents. Nanomedicine (Lond) (2009) 1.15
Selective zinc sensor molecules with various affinities for Zn2+, revealing dynamics and regional distribution of synaptically released Zn2+ in hippocampal slices. J Am Chem Soc (2005) 1.15
Design and synthesis of fluorescent probes for selective detection of highly reactive oxygen species in mitochondria of living cells. J Am Chem Soc (2007) 1.14
Development of an iminocoumarin-based zinc sensor suitable for ratiometric fluorescence imaging of neuronal zinc. J Am Chem Soc (2007) 1.14
Highly activatable and rapidly releasable caged fluorescein derivatives. J Am Chem Soc (2007) 1.12
Hypoxia-sensitive fluorescent probes for in vivo real-time fluorescence imaging of acute ischemia. J Am Chem Soc (2010) 1.10
Blockade of inflammatory responses by a small-molecule inhibitor of the Rac activator DOCK2. Chem Biol (2012) 1.09
Red fluorescent probe for monitoring the dynamics of cytoplasmic calcium ions. Angew Chem Int Ed Engl (2013) 1.08
Fluorescence endoscopic detection of murine colitis-associated colon cancer by topically applied enzymatically rapid-activatable probe. Gut (2012) 1.07
Tunable design strategy for fluorescence probes based on 4-substituted BODIPY chromophore: improvement of highly sensitive fluorescence probe for nitric oxide. Anal Bioanal Chem (2006) 1.07
Development of a far-red to near-infrared fluorescence probe for calcium ion and its application to multicolor neuronal imaging. J Am Chem Soc (2011) 1.06
Targeted optical imaging of cancer cells using lectin-binding BODIPY conjugated avidin. Biochem Biophys Res Commun (2006) 1.05
Adipose tissue-derived stem cells inhibit neointimal formation in a paracrine fashion in rat femoral artery. Am J Physiol Heart Circ Physiol (2009) 1.05
A novel, cell-permeable, fluorescent probe for ratiometric imaging of zinc ion. J Am Chem Soc (2002) 1.04
In vivo spectral fluorescence imaging of submillimeter peritoneal cancer implants using a lectin-targeted optical agent. Neoplasia (2006) 1.04
Time-resolved long-lived luminescence imaging method employing luminescent lanthanide probes with a new microscopy system. J Am Chem Soc (2007) 1.03
Development of an Si-rhodamine-based far-red to near-infrared fluorescence probe selective for hypochlorous acid and its applications for biological imaging. J Am Chem Soc (2011) 1.03
A simple and effective strategy to increase the sensitivity of fluorescence probes in living cells. J Am Chem Soc (2009) 1.03
Rational design and development of near-infrared-emitting firefly luciferins available in vivo. Angew Chem Int Ed Engl (2012) 1.02