Published in Neuroscience on January 01, 2002
Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling. Brain (2009) 1.49
Microglial p38α MAPK is critical for LPS-induced neuron degeneration, through a mechanism involving TNFα. Mol Neurodegener (2011) 1.03
Protein kinase D1 is essential for MyD88-dependent TLR signaling pathway. J Immunol (2009) 0.97
Regulation of microglia activity by glaucocalyxin-A: attenuation of lipopolysaccharide-stimulated neuroinflammation through NF-κB and p38 MAPK signaling pathways. PLoS One (2013) 0.91
Generation of reactive oxygen species in 1-methyl-4-phenylpyridinium (MPP+) treated dopaminergic neurons occurs as an NADPH oxidase-dependent two-wave cascade. J Neuroinflammation (2011) 0.89
Protein kinase D1: a new component in TLR9 signaling. J Immunol (2008) 0.89
Protein kinase D1 is essential for the proinflammatory response induced by hypersensitivity pneumonitis-causing thermophilic actinomycetes Saccharopolyspora rectivirgula. J Immunol (2010) 0.88
Naloxone ameliorates retinal lesions in Ccl2/Cx3cr1 double-deficient mice via modulation of microglia. Invest Ophthalmol Vis Sci (2011) 0.87
2-cyclohexylamino-5,8-dimethoxy-1,4-naphthoquinone inhibits LPS-induced BV2 microglial activation through MAPK/NF-kB signaling pathways. Heliyon (2016) 0.75
Group B Streptococci Induce Proinflammatory Responses via a Protein Kinase D1-Dependent Pathway. J Immunol (2017) 0.75
Job stress, satisfaction, and mental health among general practitioners before and after introduction of new contract. BMJ (1992) 11.01
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell (1993) 9.93
The molecular basis of Turcot's syndrome. N Engl J Med (1995) 6.65
Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature (1994) 6.21
Epitaxial BiFeO3 multiferroic thin film heterostructures. Science (2003) 6.14
Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer. Cancer Res (1995) 5.26
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol Cell (2001) 5.19
Crystal structure of a MAT alpha 2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions. Cell (1991) 5.14
Specific inhibition of Stat3 signal transduction by PIAS3. Science (1997) 4.74
Mismatch repair deficiency in phenotypically normal human cells. Science (1995) 3.55
Job satisfaction and occupational stress among general practitioners--a pilot study. J R Coll Gen Pract (1988) 3.54
Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia. J Med Genet (2004) 3.45
Cancer risk associated with germline DNA mismatch repair gene mutations. Hum Mol Genet (1997) 3.41
The relationship between job satisfaction and health: a meta-analysis. Occup Environ Med (2005) 3.31
Rapid elimination of low-copy DNA sequences in polyploid wheat: a possible mechanism for differentiation of homoeologous chromosomes. Genetics (1997) 3.28
Mutations of GTBP in genetically unstable cells. Science (1995) 3.23
Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis. Cell Prolif (2012) 3.18
Chondrogenic differentiation of mesenchymal stem cells from bone marrow: differentiation-dependent gene expression of matrix components. Exp Cell Res (2001) 3.06
Kinetic characterization and cross-resistance patterns of HIV-1 protease mutants selected under drug pressure. Biochemistry (1995) 2.90
Automatic adjustment of pacemaker stimulation output correlated with continuously monitored capture thresholds: a multicenter study. European Microny Study Group. Pacing Clin Electrophysiol (1998) 2.76
Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia. J Neurosci (2000) 2.75
A molecular, isozyme and morphological map of the barley (Hordeum vulgare) genome. Theor Appl Genet (1993) 2.66
Efficiency of signalling through cytokine receptors depends critically on receptor orientation. Nature (1998) 2.65
A katanin-like protein regulates normal cell wall biosynthesis and cell elongation. Plant Cell (2001) 2.63
MSH2 deficient mice are viable and susceptible to lymphoid tumours. Nat Genet (1995) 2.49
The promoter-regulatory region of the major immediate-early gene of human cytomegalovirus responds to T-lymphocyte stimulation and contains functional cyclic AMP-response elements. J Virol (1989) 2.32
Compartmentalization of a CD4+ T lymphocyte subpopulation in tuberculous pleuritis. J Immunol (1989) 2.27
NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation. Oncogene (2011) 2.22
Identifying distress among general practitioners: predictors of psychological ill-health and job dissatisfaction. Soc Sci Med (1993) 2.15
Health and safety problems associated with long working hours: a review of the current position. Occup Environ Med (1997) 2.11
Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase. Mol Cell (1998) 2.00
The Aspergillus cytoplasmic dynein heavy chain and NUDF localize to microtubule ends and affect microtubule dynamics. Curr Biol (2001) 1.96
MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1. Oncogene (2011) 1.94
Vav2 is an activator of Cdc42, Rac1, and RhoA. J Biol Chem (2000) 1.93
Contingent employment, health and sickness absence. Scand J Work Environ Health (2001) 1.91
Structural basis of the recognition of the dishevelled DEP domain in the Wnt signaling pathway. Nat Struct Biol (2000) 1.85
Role for ceramide in cell cycle arrest. J Biol Chem (1995) 1.83
Job satisfaction, mental health, and job stressors among general dental practitioners in the UK. Br Dent J (1987) 1.83
Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes. Mol Psychiatry (2006) 1.71
Establishment of a hepatocellular carcinoma cell line with unique metastatic characteristics through in vivo selection and screening for metastasis-related genes through cDNA microarray. J Cancer Res Clin Oncol (2002) 1.69
Gamma-S crystallin gene (CRYGS) mutation causes dominant progressive cortical cataract in humans. J Med Genet (2005) 1.68
Prolonged insulin independence after islet allotransplants in recipients with type 1 diabetes. Am J Transplant (2008) 1.68
Assignment of the human p27Kip1 gene to 12p13 and its analysis in leukemias. Cancer Res (1995) 1.67
Chronic microglial activation and progressive dopaminergic neurotoxicity. Biochem Soc Trans (2007) 1.63
Role for ceramide as an endogenous mediator of Fas-induced cytotoxicity. Proc Natl Acad Sci U S A (1995) 1.62
Occupational stress in health service employees. Health Serv Manage Res (1990) 1.56
Research in stress, coping, and health: theoretical and methodological issues. Psychol Med (1988) 1.52
Venous thromboembolism risk in relation to use of different types of postmenopausal hormone therapy in a large prospective study. J Thromb Haemost (2012) 1.52
Strong constraints on the rare decays B(s)(0) → μ+ μ- and B0 → μ+ μ-. Phys Rev Lett (2012) 1.50
Target imbalance: disparity of Borrelia burgdorferi genetic material in synovial fluid from Lyme arthritis patients. J Infect Dis (1994) 1.50
Paraptosis: mediation by MAP kinases and inhibition by AIP-1/Alix. Cell Death Differ (2004) 1.50
First observation of the decays B(0) → D(+)K(-)π(+)π(-) and B(-) → D(0)K(-)π(+)π(-). Phys Rev Lett (2012) 1.50
Thioredoxin peroxidase is a novel inhibitor of apoptosis with a mechanism distinct from that of Bcl-2. J Biol Chem (1997) 1.49
Distinct effects of PIAS proteins on androgen-mediated gene activation in prostate cancer cells. Oncogene (2001) 1.48
The histopathology of fibrous dysplasia of bone in patients with activating mutations of the Gs alpha gene: site-specific patterns and recurrent histological hallmarks. J Pathol (1999) 1.48
Structure of HIV-1 protease with KNI-272, a tight-binding transition-state analog containing allophenylnorstatine. Structure (1995) 1.47
Polymerase delta variants in RER colorectal tumours. Nat Genet (1995) 1.47
Emerging HIV infections with distinct subtypes of HIV-1 infection among injection drug users from geographically separate locations in Guangxi Province, China. J Acquir Immune Defic Syndr (1999) 1.45
Determination of the X(3872) meson quantum numbers. Phys Rev Lett (2013) 1.42
Blueprint for antimicrobial hit discovery targeting metabolic networks. Proc Natl Acad Sci U S A (2010) 1.42
Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity. Neuroscience (2007) 1.42
Local Thermal Fixing of a Photorefractive LiNbO(3) Hologram by use of a CO(2) Laser. Appl Opt (1998) 1.39
Starling forces that oppose filtration after tissue oncotic pressure is increased. Am J Physiol Heart Circ Physiol (2000) 1.35
Heritable alteration in DNA methylation induced by nitrogen-deficiency stress accompanies enhanced tolerance by progenies to the stress in rice (Oryza sativa L.). J Plant Physiol (2011) 1.33
Endometrial response to the intrauterine device. Am J Obstet Gynecol (1966) 1.32
Sandpile on scale-free networks. Phys Rev Lett (2003) 1.32
Identification of a phragmoplast-associated kinesin-related protein in higher plants. Curr Biol (2000) 1.30
Expression of neutral sphingomyelinase identifies a distinct pool of sphingomyelin involved in apoptosis. J Biol Chem (1997) 1.29
Widespread expression of perlecan proteoglycan in basement membranes and extracellular matrices of human tissues as detected by a novel monoclonal antibody against domain III and by in situ hybridization. J Histochem Cytochem (1994) 1.29
The "8-kD" cytoplasmic dynein light chain is required for nuclear migration and for dynein heavy chain localization in Aspergillus nidulans. J Cell Biol (1998) 1.28
Efficient Baylis--Hillman reaction using stoichiometric base catalyst and an aqueous medium. J Org Chem (2001) 1.28
Adhesion receptor expression by hematopoietic cell lines and murine progenitors: modulation by cytokines and cell cycle status. Exp Hematol (1999) 1.27
Helmets for preventing injury in motorcycle riders. Cochrane Database Syst Rev (2004) 1.26
Rho and rho kinase modulation of barrier properties: cultured endothelial cells and intact microvessels of rats and mice. J Physiol (2002) 1.26
A novel plant kinesin-related protein specifically associates with the phragmoplast organelles. Plant Cell (2001) 1.25
Transglutaminase 2 suppresses apoptosis by modulating caspase 3 and NF-kappaB activity in hypoxic tumor cells. Oncogene (2009) 1.25
Structural basis of drug resistance for the V82A mutant of HIV-1 proteinase. Nat Struct Biol (1995) 1.25
A novel intracellular epithelial cell tyrosine kinase is expressed in the skin and gastrointestinal tract. Oncogene (1995) 1.25
Roles of the PI-3K and MEK pathways in Ras-mediated chemoresistance in breast cancer cells. Br J Cancer (2003) 1.25
Serological survey of 2009 H1N1 influenza in residents of Beijing, China. Epidemiol Infect (2010) 1.24
Cyclooxygenase-2-deficient mice are resistant to 1-methyl-4-phenyl1, 2, 3, 6-tetrahydropyridine-induced damage of dopaminergic neurons in the substantia nigra. Neurosci Lett (2002) 1.23
Serum pepsinogens and risk of gastric and oesophageal cancers in the General Population Nutrition Intervention Trial cohort. Gut (2009) 1.23
Low-voltage, low-power, organic light-emitting transistors for active matrix displays. Science (2011) 1.23
Microvascular permeability and number of tight junctions are modulated by cAMP. Am J Physiol (1998) 1.23
First observation of CP violation in the decays of B(s)0 mesons. Phys Rev Lett (2013) 1.21
Murine model of Clostridium difficile infection with aged gnotobiotic C57BL/6 mice and a BI/NAP1 strain. J Infect Dis (2010) 1.19
Plant natural compounds: targeting pathways of autophagy as anti-cancer therapeutic agents. Cell Prolif (2012) 1.19
Functional cooperation of miR-125a, miR-125b, and miR-205 in entinostat-induced downregulation of erbB2/erbB3 and apoptosis in breast cancer cells. Cell Death Dis (2013) 1.17
Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF. Curr Biol (1999) 1.17
Interleukin 1beta facilitates bone cancer pain in rats by enhancing NMDA receptor NR-1 subunit phosphorylation. Neuroscience (2008) 1.15
The gene encoding the T-box factor Tbx2 is a target for the microphthalmia-associated transcription factor in melanocytes. J Biol Chem (2000) 1.15
Homeobox gene IRX1 is a tumor suppressor gene in gastric carcinoma. Oncogene (2010) 1.14
Polyphenolic acids from mint (the aerial of Mentha haplocalyx Briq.) with DPPH radical scavenging activity. J Food Sci (2010) 1.13
Ceramide generation by two distinct pathways in tumor necrosis factor alpha-induced cell death. FEBS Lett (2001) 1.12
Mutations in the heavy chain of cytoplasmic dynein suppress the nudF nuclear migration mutation of Aspergillus nidulans. Mol Gen Genet (1997) 1.12
Transferrin is an insulin-like growth factor-binding protein-3 binding protein. J Clin Endocrinol Metab (2001) 1.12
Uterine natural killer cells are targets for a trophoblast cell-specific cytokine, prolactin-like protein A. Endocrinology (1999) 1.12