Published in J Biol Chem on October 09, 2002
Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. Nat Genet (2008) 6.10
Genomic imprinting in development, growth, behavior and stem cells. Development (2014) 1.23
p75NTR-dependent, myelin-mediated axonal degeneration regulates neural connectivity in the adult brain. Nat Neurosci (2010) 1.22
Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures. J Neurosci (2008) 1.19
MAGE-A1 interacts with adaptor SKIP and the deacetylase HDAC1 to repress transcription. Nucleic Acids Res (2004) 1.17
Nuclear localization of the p75 neurotrophin receptor intracellular domain. J Biol Chem (2009) 1.11
p75 neurotrophin receptor-mediated apoptosis in sympathetic neurons involves a biphasic activation of JNK and up-regulation of tumor necrosis factor-alpha-converting enzyme/ADAM17. J Biol Chem (2010) 1.09
NRAGE, a p75NTR adaptor protein, is required for developmental apoptosis in vivo. Cell Death Differ (2008) 0.99
The neurotrophins and their role in Alzheimer's disease. Curr Neuropharmacol (2011) 0.98
p75 neurotrophin receptor mediates apoptosis in transit-amplifying cells and its overexpression restores cell death in psoriatic keratinocytes. Cell Death Differ (2010) 0.94
Interaction of MAGED1 with nuclear receptors affects circadian clock function. EMBO J (2010) 0.94
Prognostic relevance of melanoma antigen D1 expression in colorectal carcinoma. J Transl Med (2012) 0.93
Protective effects of octacosanol on 6-hydroxydopamine-induced Parkinsonism in rats via regulation of ProNGF and NGF signaling. Acta Pharmacol Sin (2010) 0.90
Proneurotrophins, seizures, and neuronal apoptosis. Neuroscientist (2010) 0.88
The ubiquitin ligase Praja1 reduces NRAGE expression and inhibits neuronal differentiation of PC12 cells. PLoS One (2013) 0.84
Synaptic dysfunction in human immunodeficiency virus type-1-positive subjects: inflammation or impaired neuronal plasticity? J Intern Med (2013) 0.83
Human immunodeficiency virus-associated dementia: a link between accumulation of viral proteins and neuronal degeneration. Curr Trends Neurol (2015) 0.82
Genome-wide differential gene expression in immortalized DF-1 chicken embryo fibroblast cell line. BMC Genomics (2011) 0.81
VGF (TLQP-62)-induced neurogenesis targets early phase neural progenitor cells in the adult hippocampus and requires glutamate and BDNF signaling. Stem Cell Res (2014) 0.81
The modular systems biology approach to investigate the control of apoptosis in Alzheimer's disease neurodegeneration. BMC Neurosci (2006) 0.80
Interactions of prion protein with intracellular proteins: so many partners and no consequences? Cell Mol Neurobiol (2009) 0.79
A small peptide modeled after the NRAGE repeat domain inhibits XIAP-TAB1-TAK1 signaling for NF-κB activation and apoptosis in P19 cells. PLoS One (2011) 0.76
Mapping of NRAGE domains reveals clues to cell viability in BMP signaling. Apoptosis (2010) 0.76
Modulation of p75 neurotrophin receptor under hypoxic conditions induces migration and invasion of C6 glioma cells. Clin Exp Metastasis (2014) 0.76
Arrestins in apoptosis. Handb Exp Pharmacol (2014) 0.75
Anti-parkinsonian effects of octacosanol in 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine-treated mice. Neural Regen Res (2012) 0.75
p75 Neurotrophin Receptor in the Skin: Beyond Its Neurotrophic Function. Front Med (Lausanne) (2017) 0.75
Prediction of years of life after diagnosis of breast cancer using omics and omic-by-treatment interactions. Eur J Hum Genet (2017) 0.75
Implication of the neurotrophin receptor p75(NTR) in vascular diseases: beyond the eye. Expert Rev Ophthalmol (2016) 0.75
cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Mol Cell (2008) 5.89
De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia. Proc Natl Acad Sci U S A (2010) 3.13
Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2. Immunity (2009) 2.91
Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi. Nat Cell Biol (2002) 2.50
Neurotrophin signaling through the p75 neurotrophin receptor. Prog Neurobiol (2002) 2.39
Nuclear factor kappa B signaling regulates neuronal morphology and cocaine reward. J Neurosci (2009) 2.25
Constitutive nuclear factor-kappa B activity is required for central neuron survival. J Neurosci (2002) 1.95
Vasculature guides migrating neuronal precursors in the adult mammalian forebrain via brain-derived neurotrophic factor signaling. J Neurosci (2009) 1.89
Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons. Neuron (2006) 1.74
An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1. Biochem J (2012) 1.71
Mutations in the calcium-related gene IL1RAPL1 are associated with autism. Hum Mol Genet (2008) 1.66
AEG3482 is an antiapoptotic compound that inhibits Jun kinase activity and cell death through induced expression of heat shock protein 70. Chem Biol (2006) 1.64
Apoptosis induced by p75NTR overexpression requires Jun kinase-dependent phosphorylation of Bad. J Neurosci (2003) 1.36
The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface. Hum Mol Genet (2006) 1.29
The p75 neurotrophin receptor: multiple interactors and numerous functions. Prog Brain Res (2004) 1.26
Excitotoxic death of retinal neurons in vivo occurs via a non-cell-autonomous mechanism. J Neurosci (2009) 1.26
Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis. J Neurosci (2004) 1.24
Nuclear factor-kappaB induced by doxorubicin is deficient in phosphorylation and acetylation and represses nuclear factor-kappaB-dependent transcription in cancer cells. Cancer Res (2005) 1.16
LGI1 is a Nogo receptor 1 ligand that antagonizes myelin-based growth inhibition. J Neurosci (2010) 1.14
K252a and CEP1347 are neuroprotective compounds that inhibit mixed-lineage kinase-3 and induce activation of Akt and ERK. J Biol Chem (2002) 1.12
Selective, reversible caspase-3 inhibitor is neuroprotective and reveals distinct pathways of cell death after neonatal hypoxic-ischemic brain injury. J Biol Chem (2002) 1.11
ProNGF induces TNFalpha-dependent death of retinal ganglion cells through a p75NTR non-cell-autonomous signaling pathway. Proc Natl Acad Sci U S A (2010) 1.10
Protein kinase A activation promotes plasma membrane insertion of DCC from an intracellular pool: A novel mechanism regulating commissural axon extension. J Neurosci (2004) 1.10
Tumor necrosis factor-alpha triggers mucus production in airway epithelium through an IkappaB kinase beta-dependent mechanism. J Biol Chem (2005) 1.09
p75 neurotrophin receptor reduces ligand-induced Trk receptor ubiquitination and delays Trk receptor internalization and degradation. EMBO Rep (2005) 1.07
TRPC channels underlie cholinergic plateau potentials and persistent activity in entorhinal cortex. Hippocampus (2011) 1.06
Proneurotrophins require endocytosis and intracellular proteolysis to induce TrkA activation. J Biol Chem (2008) 1.05
Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development. Hum Mol Genet (2008) 1.05
A pro-apoptotic fragment of the p75 neurotrophin receptor is expressed in p75NTRExonIV null mice. J Neurosci (2004) 1.02
Soluble adenylyl cyclase is not required for axon guidance to netrin-1. J Neurosci (2008) 0.99
XIAP regulates caspase activity in degenerating axons. Cell Rep (2013) 0.99
Hypo-osmolar stress induces p75NTR expression by activating Sp1-dependent transcription. J Neurosci (2007) 0.98
Apoptotic sensitivity of murine IAP-deficient cells. Biochem J (2008) 0.97
The p75NTR intracellular domain generated by neurotrophin-induced receptor cleavage potentiates Trk signaling. J Cell Sci (2010) 0.96
Differential efficacy of caspase inhibitors on apoptosis markers during sepsis in rats and implication for fractional inhibition requirements for therapeutics. J Exp Med (2004) 0.96
Stabilization of p73 by nuclear IkappaB kinase-alpha mediates cisplatin-induced apoptosis. J Biol Chem (2007) 0.95
Gob-5 is not essential for mucus overproduction in preclinical murine models of allergic asthma. Am J Respir Cell Mol Biol (2005) 0.94
p75 neurotrophin receptor cleavage by α- and γ-secretases is required for neurotrophin-mediated proliferation of brain tumor-initiating cells. J Biol Chem (2014) 0.91
Something old, something new: BDNF-induced neuron survival requires TRPC channel function. Nat Neurosci (2007) 0.91
ASPP1/2 regulate p53-dependent death of retinal ganglion cells through PUMA and Fas/CD95 activation in vivo. J Neurosci (2013) 0.89
Trk-dependent ADAM17 activation facilitates neurotrophin survival signaling. FASEB J (2011) 0.88
TRAF6-dependent NF-kB transcriptional activity during mouse development. Dev Dyn (2004) 0.88
Expression analysis of a novel p75(NTR) signaling protein, which regulates cell cycle progression and apoptosis. Mech Dev (2002) 0.86
Neuroprotective effects of M826, a reversible caspase-3 inhibitor, in the rat malonate model of Huntington's disease. Br J Pharmacol (2004) 0.86
Developing a methodology for carbon isotope analysis of lacustrine diatoms. Rapid Commun Mass Spectrom (2011) 0.85
Interaction and antagonistic roles of NF-κB and Hes6 in the regulation of cortical neurogenesis. Mol Cell Biol (2013) 0.81
Wengen, the sole tumour necrosis factor receptor in Drosophila, collaborates with moesin to control photoreceptor axon targeting during development. PLoS One (2013) 0.80
Photic injury promotes cleavage of p75NTR by TACE and nuclear trafficking of the p75 intracellular domain. Mol Cell Neurosci (2007) 0.80
Stress-induced expression of the p75 neurotrophin receptor is regulated by O-GlcNAcylation of the Sp1 transcription factor. J Neurochem (2010) 0.80
Solid phase synthesis of selective caspase-3 peptide inhibitors. Bioorg Med Chem (2004) 0.80
Solid-phase analogue synthesis of caspase-3 inhibitors via palladium-catalyzed amination of 3-bromopyrazinones. Bioorg Med Chem Lett (2007) 0.80
Neurotrophins in the regulation of cellular survival and death. Handb Exp Pharmacol (2014) 0.79
Observations on the function of nuclear factor kappa B (NF-kappaB) in the survival of adult primary sensory neurons after nerve injury. Mol Cell Neurosci (2008) 0.77
p75NTR-dependent Rac1 activation requires receptor cleavage and activation of an NRAGE and NEDD9 signaling cascade. J Cell Sci (2015) 0.77
Getting RIP'd Stunts Your Growth. Neuron (2005) 0.75
Lipophilic versus hydrogen-bonding effect in P3 on potency and selectivity of valine aspartyl ketones as caspase 3 inhibitors. Bioorg Med Chem Lett (2005) 0.75
Correlating the fractional inhibition of caspase-3 in NT2 cells with apoptotic markers using an active-caspase-3 enzyme-linked immunosorbent assay. Anal Biochem (2005) 0.75
Nicotinyl aspartyl ketones as inhibitors of caspase-3. Bioorg Med Chem Lett (2003) 0.75