Published in J Chromatogr A on September 27, 2002
Rational design of alpha-helical antimicrobial peptides with enhanced activities and specificity/therapeutic index. J Biol Chem (2005) 2.28
Determination of intrinsic hydrophilicity/hydrophobicity of amino acid side chains in peptides in the absence of nearest-neighbor or conformational effects. Biopolymers (2006) 1.46
Rational design of alpha-helical antimicrobial peptides with enhanced activities and specificity/therapeutic index. J Biol Chem (2005) 2.28
Role of peptide hydrophobicity in the mechanism of action of alpha-helical antimicrobial peptides. Antimicrob Agents Chemother (2006) 1.87
LINE-1 retrotransposition requires the nucleic acid chaperone activity of the ORF1 protein. J Mol Biol (2005) 1.78
Effects of net charge and the number of positively charged residues on the biological activity of amphipathic alpha-helical cationic antimicrobial peptides. Biopolymers (2008) 1.51
Structural characterization of the SARS-coronavirus spike S fusion protein core. J Biol Chem (2004) 1.48
Determination of intrinsic hydrophilicity/hydrophobicity of amino acid side chains in peptides in the absence of nearest-neighbor or conformational effects. Biopolymers (2006) 1.46
The Pseudomonas aeruginosa type IV pilin receptor binding domain functions as an adhesin for both biotic and abiotic surfaces. Mol Microbiol (2006) 1.26
Designing heterodimeric two-stranded alpha-helical coiled-coils. Effects of hydrophobicity and alpha-helical propensity on protein folding, stability, and specificity. J Biol Chem (2002) 1.23
A novel method to measure self-association of small amphipathic molecules: temperature profiling in reversed-phase chromatography. J Biol Chem (2003) 1.21
Comparison of biophysical and biologic properties of alpha-helical enantiomeric antimicrobial peptides. Chem Biol Drug Des (2006) 1.20
Peptide nanoparticles as novel immunogens: design and analysis of a prototypic severe acute respiratory syndrome vaccine. Chem Biol Drug Des (2009) 1.18
Stabilizing and destabilizing clusters in the hydrophobic core of long two-stranded alpha-helical coiled-coils. J Biol Chem (2004) 1.12
Counteracting roles of AMP deaminase and AMP kinase in the development of fatty liver. PLoS One (2012) 1.12
Structure-activity relationships of de novo designed cyclic antimicrobial peptides based on gramicidin S. Biopolymers (2003) 1.08
Optimization of microbial specificity in cyclic peptides by modulation of hydrophobicity within a defined structural framework. J Biol Chem (2001) 1.08
Probing the structural determinants of type II' beta-turn formation in peptides and proteins. J Am Chem Soc (2002) 1.08
Real-time monitoring of the interactions of two-stranded de novo designed coiled-coils: effect of chain length on the kinetic and thermodynamic constants of binding. Biochemistry (2003) 1.07
Temperature profiling of polypeptides in reversed-phase liquid chromatography. I. Monitoring of dimerization and unfolding of amphipathic alpha-helical peptides. J Chromatogr A (2003) 1.05
Temperature profiling of polypeptides in reversed-phase liquid chromatography. II. Monitoring of folding and stability of two-stranded alpha-helical coiled-coils. J Chromatogr A (2003) 1.04
Temperature selectivity effects in reversed-phase liquid chromatography due to conformation differences between helical and non-helical peptides. J Chromatogr A (2003) 1.04
Surface nanocrystallization of stainless steel for reduced biofilm adherence. Nanotechnology (2008) 1.02
Effect of variations in the structure of a polyleucine-based alpha-helical transmembrane peptide on its interaction with phosphatidylethanolamine Bilayers. Biophys J (2004) 1.02
Preparative reversed-phase high-performance liquid chromatography collection efficiency for an antimicrobial peptide on columns of varying diameters (1mm to 9.4mm I.D.). J Chromatogr A (2006) 1.01
Capillary electrophoresis of cationic random coil peptide standards: effect of anionic ion-pairing reagents and comparison with reversed-phase chromatography. Electrophoresis (2004) 1.01
Effect of variations in the structure of a polyleucine-based alpha-helical transmembrane peptide on its interaction with phosphatidylcholine bilayers. Biochemistry (2002) 1.01
Clustering of large hydrophobes in the hydrophobic core of two-stranded alpha-helical coiled-coils controls protein folding and stability. J Biol Chem (2003) 1.00
Helix capping interactions stabilize the N-terminus of the kinesin neck coiled-coil. J Struct Biol (2002) 1.00
Isothermal titration calorimetry studies of the binding of a rationally designed analogue of the antimicrobial peptide gramicidin s to phospholipid bilayer membranes. Biochemistry (2005) 0.98
Regulation of the amino-terminal transcription activation domain of progesterone receptor by a cofactor-induced protein folding mechanism. Mol Cell Biol (2005) 0.93
Fourier transform infrared spectroscopic study of the interactions of a strongly antimicrobial but weakly hemolytic analogue of gramicidin S with lipid micelles and lipid bilayer membranes. Biochemistry (2003) 0.93
Effect of ring size on conformation and biological activity of cyclic cationic antimicrobial peptides. J Med Chem (2009) 0.93
A de novo designed template for generating conformation-specific antibodies that recognize alpha-helices in proteins. J Biol Chem (2002) 0.92
Synthetic peptide vaccine and antibody therapeutic development: prevention and treatment of Pseudomonas aeruginosa. Biopolymers (2003) 0.92
Defining the minimum size of a hydrophobic cluster in two-stranded alpha-helical coiled-coils: effects on protein stability. Protein Sci (2004) 0.92
Tracking membrane protein association in model membranes. PLoS One (2009) 0.92
Isothermal titration calorimetry studies of the binding of the antimicrobial peptide gramicidin S to phospholipid bilayer membranes. Biochemistry (2005) 0.91
Effects of hydrophobicity on the antifungal activity of alpha-helical antimicrobial peptides. Chem Biol Drug Des (2008) 0.91
Interaction of gramicidin S and its aromatic amino-acid analog with phospholipid membranes. Biophys J (2008) 0.91
The role of unstructured highly charged regions on the stability and specificity of dimerization of two-stranded alpha-helical coiled-coils: analysis of the neck-hinge region of the kinesin-like motor protein Kif3A. J Struct Biol (2002) 0.90
Unique stabilizing interactions identified in the two-stranded alpha-helical coiled-coil: crystal structure of a cortexillin I/GCN4 hybrid coiled-coil peptide. Protein Sci (2003) 0.90
Variation of the lateral mobility of transmembrane peptides with hydrophobic mismatch. J Phys Chem B (2010) 0.90
Effect of variations in the structure of a polyleucine-based alpha-helical transmembrane peptide on its interaction with phosphatidylglycerol bilayers. Biochemistry (2004) 0.89
NMR solution structure of a highly stable de novo heterodimeric coiled-coil. Biopolymers (2004) 0.89
Structural and functional analysis of ProQ: an osmoregulatory protein of Escherichia coli. Biochemistry (2007) 0.87
Comparison of reversed-phase liquid chromatography and hydrophilic interaction/cation-exchange chromatography for the separation of amphipathic alpha-helical peptides with L- and D-amino acid substitutions in the hydrophilic face. J Chromatogr A (2003) 0.87
Template-based coiled-coil antigens elicit neutralizing antibodies to the SARS-coronavirus. J Struct Biol (2006) 0.87
Anti-tuberculosis activity of α-helical antimicrobial peptides: de novo designed L- and D-enantiomers versus L- and D-LL-37. Protein Pept Lett (2011) 0.87
Mixed-mode hydrophilic interaction/cation-exchange chromatography (HILIC/CEX) of peptides and proteins. J Sep Sci (2008) 0.86
Solution structure of the C-terminal antiparallel coiled-coil domain from Escherichia coli osmosensor ProP. J Mol Biol (2003) 0.86
A D-peptide analog of the second extracellular loop of claudin-3 and -4 leads to mislocalized claudin and cellular apoptosis in mammary epithelial cells. Chem Biol Drug Des (2011) 0.86
Structure-activity relationships of diastereomeric lysine ring size analogs of the antimicrobial peptide gramicidin S: mechanism of action and discrimination between bacterial and animal cell membranes. J Biol Chem (2004) 0.85
The relationship between the binding to and permeabilization of phospholipid bilayer membranes by GS14dK4, a designed analog of the antimicrobial peptide gramicidin S. Biochim Biophys Acta (2007) 0.85
Preparative reversed-phase liquid chromatography of proteins from rabbit skeletal troponin, a multi-protein complex. J Chromatogr A (2002) 0.85
Animal protection and structural studies of a consensus sequence vaccine targeting the receptor binding domain of the type IV pilus of Pseudomonas aeruginosa. J Mol Biol (2007) 0.85
Capillary zone electrophoresis of alpha-helical diastereomeric peptide pairs with anionic ion-pairing reagents. J Chromatogr A (2004) 0.84
Advantages of a synthetic peptide immunogen over a protein immunogen in the development of an anti-pilus vaccine for Pseudomonas aeruginosa. Chem Biol Drug Des (2009) 0.84
Core residue replacements cause coiled-coil orientation switching in vitro and in vivo: structure-function correlations for osmosensory transporter ProP. Biochemistry (2007) 0.83
HPLC analysis and purification of peptides. Methods Mol Biol (2007) 0.83
Biophysical characterization of HRC peptide analogs interaction with heptad repeat regions of the SARS-coronavirus Spike fusion protein core. J Struct Biol (2006) 0.82
Critical interactions in the stability control region of tropomyosin. J Struct Biol (2010) 0.82
Capillary electrophoresis of synthetic peptide standards varying in charge and hydrophobicity. Electrophoresis (2003) 0.82
Reversed-phase HPLC of peptides: Assessing column and solvent selectivity on standard, polar-embedded and polar endcapped columns. J Sep Sci (2010) 0.81
One-step purification of a recombinant protein from a whole cell extract by reversed-phase high-performance liquid chromatography. J Chromatogr A (2006) 0.81
Kinetic analysis of the interactions between troponin C and the C-terminal troponin I regulatory region and validation of a new peptide delivery/capture system used for surface plasmon resonance. J Mol Biol (2002) 0.81
Capillary electrophoresis of amphipathic alpha-helical peptide diastereomers. Electrophoresis (2004) 0.81
Ion-interaction-capillary zone electrophoresis of cationic proteomic peptide standards. J Chromatogr A (2005) 0.80
Effect of chain length on coiled-coil stability: decreasing stability with increasing chain length. Biopolymers (2004) 0.80
Mixed-mode hydrophilic interaction/cation-exchange chromatography: separation of complex mixtures of peptides of varying charge and hydrophobicity. J Sep Sci (2008) 0.80
Synthetic peptide vaccine development: measurement of polyclonal antibody affinity and cross-reactivity using a new peptide capture and release system for surface plasmon resonance spectroscopy. J Mol Recognit (2004) 0.80
Detection of alpha-helical coiled-coil dimer formation by spin-labeled synthetic peptides: a model parallel coiled-coil peptide and the antiparallel coiled coil formed by a replica of the ProP C-terminus. Biochemistry (2003) 0.79
Synthetic peptide vaccine development: designing dual epitopes into a single pilin peptide immunogen generates antibody cross-reactivity between two strains of Pseudomonas aeruginosa. Chem Biol Drug Des (2010) 0.78
Effects of net charge and the number of positively charged residues on the biological activity of amphipathic alpha-helical cationic antimicrobial peptides. Adv Exp Med Biol (2009) 0.78
The effects of ring-size analogs of the antimicrobial peptide gramicidin S on phospholipid bilayer model membranes and on the growth of Acholeplasma laidlawii B. Eur J Biochem (2002) 0.78
Ion-interaction CZE: the presence of high concentrations of ion-pairing reagents demonstrates the complex mechanisms involved in peptide separations. Electrophoresis (2007) 0.78
Expression and characterization of recombinant S2 subunit of SARS-coronavirus S fusion protein. Adv Exp Med Biol (2009) 0.77
Dissection of the fusion machine of SARS-coronavirus. Adv Exp Med Biol (2006) 0.77
Preparative reversed-phase liquid chromatography of peptides. Isocratic two-step elution system for high loads on analytical columns. J Chromatogr A (2002) 0.77
Purification and structural characterization of siderophore (corynebactin) from Corynebacterium diphtheriae. PLoS One (2012) 0.76
Design of peptide standards with the same composition and minimal sequence variation to monitor performance/selectivity of reversed-phase matrices. J Chromatogr A (2012) 0.76
Myotonic dystrophy protein kinase monoclonal antibody generation from a coiled-coil template. J Mol Recognit (2006) 0.76
Kinetic analysis of the interactions between troponin C (TnC) and troponin I (TnI) binding peptides: evidence for separate binding sites for the 'structural' N-terminus and the 'regulatory' C-terminus of TnI on TnC. J Mol Recognit (2003) 0.76
An improved approach to hydrophilic interaction chromatography of peptides: salt gradients in the presence of high isocratic acetonitrile concentrations. J Chromatogr A (2013) 0.75
Transmission of stability information through the N-domain of tropomyosin is interrupted by a stabilizing mutation (A109L) in the hydrophobic core of the stability control region (residues 97-118). J Biol Chem (2013) 0.75
Structure-guided RP-HPLC chromatography of diastereomeric α-helical peptide analogs substituted with single amino acid stereoisomers. Biomed Chromatogr (2013) 0.75
Importance of secondary structural specificity determinants in protein folding: insertion of a native beta-sheet sequence into an alpha-helical coiled-coil. Protein Sci (2002) 0.75
Hail to the editor-in-chief: an appreciation of Victor J. Hruby, outstanding scientist-mentor-leader in peptide research. J Pept Res (2005) 0.75
Unique role of clusters of electrostatic attractions in controlling the stability of two-stranded alpha-helical coiled-coils. Adv Exp Med Biol (2009) 0.75
Characterization of the proto-oncogenic and mutant forms of the transmembrane region of Neu in micelles. J Biol Chem (2004) 0.75
Comparison of proto-oncogenic and mutant forms of the transmembrane region of the Neu receptor in TFE. FEBS Lett (2003) 0.75