Published in Biopolymers on January 01, 2008
Antimicrobial peptides. Pharmaceuticals (Basel) (2013) 1.37
Alpha-helical cationic antimicrobial peptides: relationships of structure and function. Protein Cell (2010) 1.19
Cationic amphiphiles, a new generation of antimicrobials inspired by the natural antimicrobial peptide scaffold. Antimicrob Agents Chemother (2010) 1.15
A look at arginine in membranes. J Membr Biol (2010) 1.05
Identification, characterization, and recombinant expression of epidermicin NI01, a novel unmodified bacteriocin produced by Staphylococcus epidermidis that displays potent activity against Staphylococci. Antimicrob Agents Chemother (2011) 0.93
De-novo design of antimicrobial peptides for plant protection. PLoS One (2013) 0.91
Effects of hydrophobicity on the antifungal activity of alpha-helical antimicrobial peptides. Chem Biol Drug Des (2008) 0.91
Role of helicity of α-helical antimicrobial peptides to improve specificity. Protein Cell (2014) 0.90
Selective acylation enhances membrane charge sensitivity of the antimicrobial peptide mastoparan-x. Biophys J (2011) 0.88
Host-defense peptides with therapeutic potential from skin secretions of frogs from the family pipidae. Pharmaceuticals (Basel) (2014) 0.88
The electrical response of bilayers to the bee venom toxin melittin: evidence for transient bilayer permeabilization. Biochim Biophys Acta (2013) 0.88
Guanidino groups greatly enhance the action of antimicrobial peptidomimetics against bacterial cytoplasmic membranes. Biochim Biophys Acta (2014) 0.87
Contribution of structural domains to the activity of ribonuclease 7 against uropathogenic bacteria. Antimicrob Agents Chemother (2012) 0.87
Anti-tuberculosis activity of α-helical antimicrobial peptides: de novo designed L- and D-enantiomers versus L- and D-LL-37. Protein Pept Lett (2011) 0.87
Cathelicidin-like helminth defence molecules (HDMs): absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation. PLoS Negl Trop Dis (2013) 0.87
Metal-binding dependent disruption of membranes by designed helices. J Am Chem Soc (2009) 0.84
A peptide derived from phage display library exhibits antibacterial activity against E. coli and Pseudomonas aeruginosa. PLoS One (2013) 0.84
Structure, antimicrobial activities and mode of interaction with membranes of novel [corrected] phylloseptins from the painted-belly leaf frog, Phyllomedusa sauvagii. PLoS One (2013) 0.83
Identification of novel cyclic lipopeptides from a positional scanning combinatorial library with enhanced antibacterial and antibiofilm activities. Eur J Med Chem (2015) 0.83
Investigating the importance of charged residues in lantibiotics. Bioeng Bugs (2011) 0.82
Knowledge-based computational methods for identifying or designing novel, non-homologous antimicrobial peptides. Eur Biophys J (2011) 0.81
The Design and Construction of K11: A Novel α-Helical Antimicrobial Peptide. Int J Microbiol (2012) 0.81
In vitro activities of synthetic host defense propeptides processed by neutrophil elastase against cystic fibrosis pathogens. Antimicrob Agents Chemother (2011) 0.81
Comparative Evaluation of the Antimicrobial Activity of Different Antimicrobial Peptides against a Range of Pathogenic Bacteria. PLoS One (2015) 0.81
Design of embedded-hybrid antimicrobial peptides with enhanced cell selectivity and anti-biofilm activity. PLoS One (2014) 0.80
Antimicrobial Peptides: Insights into Membrane Permeabilization, Lipopolysaccharide Fragmentation and Application in Plant Disease Control. Sci Rep (2015) 0.80
Antimicrobial activity of synthetic cationic peptides and lipopeptides derived from human lactoferricin against Pseudomonas aeruginosa planktonic cultures and biofilms. BMC Microbiol (2015) 0.79
Altering the composition of caseicins A and B as a means of determining the contribution of specific residues to antimicrobial activity. Appl Environ Microbiol (2011) 0.79
An anti-infective synthetic peptide with dual antimicrobial and immunomodulatory activities. Sci Rep (2016) 0.78
Activity of Scorpion Venom-Derived Antifungal Peptides against Planktonic Cells of Candida spp. and Cryptococcus neoformans and Candida albicans Biofilms. Front Microbiol (2016) 0.77
Characterization of Histone H2A Derived Antimicrobial Peptides, Harriottins, from Sicklefin Chimaera Neoharriotta pinnata (Schnakenbeck, 1931) and Its Evolutionary Divergence with respect to CO1 and Histone H2A. ISRN Mol Biol (2013) 0.77
Modifications of natural peptides for nanoparticle and drug design. Adv Protein Chem Struct Biol (2015) 0.77
High specific selectivity and Membrane-Active Mechanism of the synthetic centrosymmetric α-helical peptides with Gly-Gly pairs. Sci Rep (2015) 0.77
Side chain hydrophobicity modulates therapeutic activity and membrane selectivity of antimicrobial peptide mastoparan-X. PLoS One (2014) 0.76
Design of an α-helical antimicrobial peptide with improved cell-selective and potent anti-biofilm activity. Sci Rep (2016) 0.76
"Specificity Determinants" Improve Therapeutic Indices of Two Antimicrobial Peptides Piscidin 1 and Dermaseptin S4 Against the Gram-negative Pathogens Acinetobacter baumannii and Pseudomonas aeruginosa. Pharmaceuticals (Basel) (2014) 0.76
A structure-property relationship study of the well-defined telodendrimers to improve hemocompatibility of nanocarriers for anticancer drug delivery. Langmuir (2014) 0.76
The PDB database is a rich source of alpha-helical anti-microbial peptides to combat disease causing pathogens. F1000Res (2014) 0.75
Chimeric peptides as implant functionalization agents for titanium alloy implants with antimicrobial properties. JOM (1989) (2015) 0.75
A rigidity-enhanced antimicrobial activity: a case for linear cationic α-helical peptide HP(2-20) and its four analogues. PLoS One (2011) 0.75
Structure-guided RP-HPLC chromatography of diastereomeric α-helical peptide analogs substituted with single amino acid stereoisomers. Biomed Chromatogr (2013) 0.75
Antimicrobial Protein Candidates from the Thermophilic Geobacillus sp. Strain ZGt-1: Production, Proteomics, and Bioinformatics Analysis. Int J Mol Sci (2016) 0.75
Transcriptome analysis of Streptococcus pneumoniae treated with the designed antimicrobial peptides, DM3. Sci Rep (2016) 0.75
Enhanced Cationic Charge is a Key Factor in Promoting Staphylocidal Activity of α-Melanocyte Stimulating Hormone via Selective Lipid Affinity. Sci Rep (2016) 0.75
Piscidin-1-analogs with double L- and D-lysine residues exhibited different conformations in lipopolysaccharide but comparable anti-endotoxin activities. Sci Rep (2017) 0.75
Antimicrobial activity and interactions of cationic peptides derived from Galleria mellonella cecropin D-like peptide with model membranes. J Antibiot (Tokyo) (2016) 0.75
Comparative Analysis of the Bacterial Membrane Disruption Effect of Two Natural Plant Antimicrobial Peptides. Front Microbiol (2017) 0.75
Interaction of a synthetic antimicrobial peptide with model membrane by fluorescence spectroscopy. Eur Biophys J (2013) 0.75
Genetic recombination in Pseudomonas aeruginosa. J Gen Microbiol (1955) 6.90
Peptide antibiotics. Lancet (1997) 6.76
Peptide antimicrobial agents. Clin Microbiol Rev (2006) 6.04
Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides. Biochim Biophys Acta (1999) 5.85
Peptide antibiotics. Antimicrob Agents Chemother (1999) 5.76
Cationic peptides: a new source of antibiotics. Trends Biotechnol (1998) 5.10
The helical hydrophobic moment: a measure of the amphiphilicity of a helix. Nature (1982) 5.01
Experimental studies of the pathogenesis of infections due to Pseudomonas aeruginosa: description of a burned mouse model. J Infect Dis (1975) 4.36
Amphipathic, alpha-helical antimicrobial peptides. Biopolymers (2000) 3.68
Passive protection by antitoxin in experimental Pseudomonas aeruginosa burn infections. Infect Immun (1977) 3.25
Plants and animals share functionally common bacterial virulence factors. Proc Natl Acad Sci U S A (2000) 3.21
Protegrin-1: a broad-spectrum, rapidly microbicidal peptide with in vivo activity. Antimicrob Agents Chemother (1997) 3.12
Incidence of exotoxin production by Pseudomonas species. Infect Immun (1977) 3.08
Electrically gated ionic channels in lipid bilayers. Q Rev Biophys (1977) 2.44
Composition and molecular weight of pili purified from Pseudomonas aeruginosa K. J Bacteriol (1977) 2.31
Rational design of alpha-helical antimicrobial peptides with enhanced activities and specificity/therapeutic index. J Biol Chem (2005) 2.28
The design of Jemboss: a graphical user interface to EMBOSS. Bioinformatics (2003) 2.22
In vitro antibacterial properties of pexiganan, an analog of magainin. Antimicrob Agents Chemother (1999) 2.10
Amphipathic alpha helical antimicrobial peptides. Eur J Biochem (2001) 1.90
Role of peptide hydrophobicity in the mechanism of action of alpha-helical antimicrobial peptides. Antimicrob Agents Chemother (2006) 1.87
Optimization of the antimicrobial activity of magainin peptides by modification of charge. FEBS Lett (2001) 1.52
Conjugation of a magainin analogue with lipophilic acids controls hydrophobicity, solution assembly, and cell selectivity. Biochemistry (2002) 1.49
Determination of intrinsic hydrophilicity/hydrophobicity of amino acid side chains in peptides in the absence of nearest-neighbor or conformational effects. Biopolymers (2006) 1.46
Antimicrobial peptide therapeutics for cystic fibrosis. Antimicrob Agents Chemother (2005) 1.44
Biological properties of structurally related alpha-helical cationic antimicrobial peptides. Infect Immun (1999) 1.40
Effect of preferred binding domains on peptide retention behavior in reversed-phase chromatography: amphipathic alpha-helices. Pept Res (1992) 1.34
Dissociation and characterization of pilin isolated from Pseudomonas aeruginosa strains PAK and PAO. Can J Biochem (1982) 1.32
Peptide hydrophobicity controls the activity and selectivity of magainin 2 amide in interaction with membranes. Biochemistry (1997) 1.29
Position-dependent hydrophobicity of the antimicrobial magainin peptide affects the mode of peptide-lipid interactions and selective toxicity. Biochemistry (2002) 1.23
A novel method to measure self-association of small amphipathic molecules: temperature profiling in reversed-phase chromatography. J Biol Chem (2003) 1.21
Comparison of biophysical and biologic properties of alpha-helical enantiomeric antimicrobial peptides. Chem Biol Drug Des (2006) 1.20
Impact of single-residue mutations on the structure and function of ovispirin/novispirin antimicrobial peptides. Protein Eng (2002) 1.14
Pseudomonas aeruginosa, Candida albicans, and device-related nosocomial infections: implications, trends, and potential approaches for control. J Ind Microbiol Biotechnol (2005) 1.10
Structure-activity relationships of de novo designed cyclic antimicrobial peptides based on gramicidin S. Biopolymers (2003) 1.08
Temperature profiling of polypeptides in reversed-phase liquid chromatography. I. Monitoring of dimerization and unfolding of amphipathic alpha-helical peptides. J Chromatogr A (2003) 1.05
Temperature profiling of polypeptides in reversed-phase liquid chromatography. II. Monitoring of folding and stability of two-stranded alpha-helical coiled-coils. J Chromatogr A (2003) 1.04
Preparative reversed-phase high-performance liquid chromatography collection efficiency for an antimicrobial peptide on columns of varying diameters (1mm to 9.4mm I.D.). J Chromatogr A (2006) 1.01
Amphiphilic alpha-helical antimicrobial peptides and their structure/function relationships. Protein Pept Lett (2005) 1.01
Cyclization of a cytolytic amphipathic alpha-helical peptide and its diastereomer: effect on structure, interaction with model membranes, and biological function. Biochemistry (2000) 0.99
Temperature selectivity in reversed-phase high performance liquid chromatography. J Chromatogr A (2002) 0.98
Factors determining the efficacy of alpha-helical antimicrobial peptides. Protein Pept Lett (2003) 0.81
Sequence analysis and membrane partitioning energies of alpha-helical antimicrobial peptides. Bioinformatics (2004) 0.78
Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances. Nat Protoc (2008) 7.92
Peptide antimicrobial agents. Clin Microbiol Rev (2006) 6.04
Pseudomonas Genome Database: improved comparative analysis and population genomics capability for Pseudomonas genomes. Nucleic Acids Res (2010) 5.23
PSICQUIC and PSISCORE: accessing and scoring molecular interactions. Nat Methods (2011) 5.01
Pseudomonas aeruginosa anaerobic respiration in biofilms: relationships to cystic fibrosis pathogenesis. Dev Cell (2002) 4.94
InnateDB: facilitating systems-level analyses of the mammalian innate immune response. Mol Syst Biol (2008) 4.61
Designing antimicrobial peptides: form follows function. Nat Rev Drug Discov (2011) 4.16
Pseudomonas aeruginosa: all roads lead to resistance. Trends Microbiol (2011) 3.49
Cerebral: a Cytoscape plugin for layout of and interaction with biological networks using subcellular localization annotation. Bioinformatics (2007) 3.39
GeneChip expression analysis of the iron starvation response in Pseudomonas aeruginosa: identification of novel pyoverdine biosynthesis genes. Mol Microbiol (2002) 3.38
Identification of tandem duplicate regulatory small RNAs in Pseudomonas aeruginosa involved in iron homeostasis. Proc Natl Acad Sci U S A (2004) 3.31
Iron and Pseudomonas aeruginosa biofilm formation. Proc Natl Acad Sci U S A (2005) 3.26
Protein interaction data curation: the International Molecular Exchange (IMEx) consortium. Nat Methods (2012) 3.17
Cationic antimicrobial peptides activate a two-component regulatory system, PmrA-PmrB, that regulates resistance to polymyxin B and cationic antimicrobial peptides in Pseudomonas aeruginosa. Mol Microbiol (2003) 3.06
Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa. Genome Res (2008) 3.03
Recognition of host immune activation by Pseudomonas aeruginosa. Science (2005) 2.84
Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Nucleic Acids Res (2008) 2.71
Cationic host defense (antimicrobial) peptides. Curr Opin Immunol (2005) 2.71
InnateDB: systems biology of innate immunity and beyond--recent updates and continuing curation. Nucleic Acids Res (2012) 2.66
Siderophore-mediated signaling regulates virulence factor production in Pseudomonasaeruginosa. Proc Natl Acad Sci U S A (2002) 2.66
Pseudomonas aeruginosa Genome Database and PseudoCAP: facilitating community-based, continually updated, genome annotation. Nucleic Acids Res (2005) 2.61
The human antimicrobial peptide LL-37 is a multifunctional modulator of innate immune responses. J Immunol (2002) 2.57
Structural transitions as determinants of the action of the calcium-dependent antibiotic daptomycin. Chem Biol (2004) 2.51
The relationship between peptide structure and antibacterial activity. Peptides (2003) 2.51
Multidrug efflux systems play an important role in the invasiveness of Pseudomonas aeruginosa. J Exp Med (2002) 2.40
Mode of action of the new antibiotic for Gram-positive pathogens daptomycin: comparison with cationic antimicrobial peptides and lipopeptides. Biochim Biophys Acta (2006) 2.35
Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37. J Immunol (2006) 2.32
Pseudomonas aeruginosa: new insights into pathogenesis and host defenses. Pathog Dis (2013) 2.32
Rational design of alpha-helical antimicrobial peptides with enhanced activities and specificity/therapeutic index. J Biol Chem (2005) 2.28
Construction of a mini-Tn5-luxCDABE mutant library in Pseudomonas aeruginosa PAO1: a tool for identifying differentially regulated genes. Genome Res (2005) 2.22
Architecture of a protein central to iron homeostasis: crystal structure and spectroscopic analysis of the ferric uptake regulator. Mol Microbiol (2003) 2.19
Inhibition of LpxC protects mice from resistant Acinetobacter baumannii by modulating inflammation and enhancing phagocytosis. MBio (2012) 2.15
Peptide arrays on cellulose support: SPOT synthesis, a time and cost efficient method for synthesis of large numbers of peptides in a parallel and addressable fashion. Nat Protoc (2007) 2.08
Alternative mechanisms of action of cationic antimicrobial peptides on bacteria. Expert Rev Anti Infect Ther (2007) 2.06
ArrayPipe: a flexible processing pipeline for microarray data. Nucleic Acids Res (2004) 2.03
High-throughput generation of small antibacterial peptides with improved activity. Nat Biotechnol (2005) 2.01
Impact of LL-37 on anti-infective immunity. J Leukoc Biol (2004) 2.01
Multifunctional cationic host defence peptides and their clinical applications. Cell Mol Life Sci (2011) 1.99
Swarming of Pseudomonas aeruginosa is a complex adaptation leading to increased production of virulence factors and antibiotic resistance. J Bacteriol (2008) 1.98
An anti-infective peptide that selectively modulates the innate immune response. Nat Biotechnol (2007) 1.97
The roles of cathelicidin LL-37 in immune defences and novel clinical applications. Curr Opin Hematol (2009) 1.92
Regulation of virulence and antibiotic resistance by two-component regulatory systems in Pseudomonas aeruginosa. FEMS Microbiol Rev (2009) 1.91
Human host defense peptide LL-37 prevents bacterial biofilm formation. Infect Immun (2008) 1.91
Can innate immunity be enhanced to treat microbial infections? Nat Rev Microbiol (2004) 1.90
Effects of the twin-arginine translocase on secretion of virulence factors, stress response, and pathogenesis. Proc Natl Acad Sci U S A (2002) 1.88
Role of peptide hydrophobicity in the mechanism of action of alpha-helical antimicrobial peptides. Antimicrob Agents Chemother (2006) 1.87
Sequence requirements and an optimization strategy for short antimicrobial peptides. Chem Biol (2006) 1.84
Ciprofloxacin induction of a susceptibility determinant in Pseudomonas aeruginosa. Antimicrob Agents Chemother (2005) 1.82
Neutrophil enhancement of Pseudomonas aeruginosa biofilm development: human F-actin and DNA as targets for therapy. J Med Microbiol (2009) 1.80
Enhanced Pseudomonas aeruginosa biofilm development mediated by human neutrophils. Infect Immun (2005) 1.79
The cationic antimicrobial peptide LL-37 modulates dendritic cell differentiation and dendritic cell-induced T cell polarization. J Immunol (2004) 1.78
LINE-1 retrotransposition requires the nucleic acid chaperone activity of the ORF1 protein. J Mol Biol (2005) 1.78
The pmrCAB operon mediates polymyxin resistance in Acinetobacter baumannii ATCC 17978 and clinical isolates through phosphoethanolamine modification of lipid A. Antimicrob Agents Chemother (2011) 1.78
A re-evaluation of the role of host defence peptides in mammalian immunity. Curr Protein Pept Sci (2005) 1.78
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen. Genome Res (2005) 1.77
Adaptive resistance to the "last hope" antibiotics polymyxin B and colistin in Pseudomonas aeruginosa is mediated by the novel two-component regulatory system ParR-ParS. Antimicrob Agents Chemother (2010) 1.74
Adaptive and mutational resistance: role of porins and efflux pumps in drug resistance. Clin Microbiol Rev (2012) 1.74
Using microarray gene signatures to elucidate mechanisms of antibiotic action and resistance. Drug Discov Today (2005) 1.74
Immune modulation by multifaceted cationic host defense (antimicrobial) peptides. Nat Chem Biol (2013) 1.73
Evidence that plant-like genes in Chlamydia species reflect an ancestral relationship between Chlamydiaceae, cyanobacteria, and the chloroplast. Genome Res (2002) 1.72
Sublethal concentrations of pleurocidin-derived antimicrobial peptides inhibit macromolecular synthesis in Escherichia coli. Antimicrob Agents Chemother (2002) 1.69
Immunomodulatory activities of small host defense peptides. Antimicrob Agents Chemother (2005) 1.67
Complex ciprofloxacin resistome revealed by screening a Pseudomonas aeruginosa mutant library for altered susceptibility. Antimicrob Agents Chemother (2008) 1.67
Endotoxin tolerance represents a distinctive state of alternative polarization (M2) in human mononuclear cells. J Immunol (2011) 1.65
Bacterial biofilm development as a multicellular adaptation: antibiotic resistance and new therapeutic strategies. Curr Opin Microbiol (2013) 1.63
Inhibition of bacterial biofilm formation and swarming motility by a small synthetic cationic peptide. Antimicrob Agents Chemother (2012) 1.63
Systems-level comparison of host-responses elicited by avian H5N1 and seasonal H1N1 influenza viruses in primary human macrophages. PLoS One (2009) 1.61
AMPer: a database and an automated discovery tool for antimicrobial peptides. Bioinformatics (2007) 1.59
Aminoglycoside efflux in Pseudomonas aeruginosa: involvement of novel outer membrane proteins. Antimicrob Agents Chemother (2003) 1.59
Potential of immunomodulatory host defense peptides as novel anti-infectives. Trends Biotechnol (2009) 1.58
Neutrophil extracellular trap (NET)-mediated killing of Pseudomonas aeruginosa: evidence of acquired resistance within the CF airway, independent of CFTR. PLoS One (2011) 1.58
The influence of iron on Pseudomonas aeruginosa physiology: a regulatory link between iron and quorum sensing. J Biol Chem (2008) 1.56
Identification of genes involved in swarming motility using a Pseudomonas aeruginosa PAO1 mini-Tn5-lux mutant library. J Bacteriol (2006) 1.54
Characterization of a proteolytically stable multifunctional host defense peptidomimetic. Chem Biol (2013) 1.49
Structural characterization of the SARS-coronavirus spike S fusion protein core. J Biol Chem (2004) 1.48
Antibody responses in adult and neonatal BALB/c mice to immunization with novel Bordetella pertussis vaccine formulations. Vaccine (2011) 1.48
INMEX--a web-based tool for integrative meta-analysis of expression data. Nucleic Acids Res (2013) 1.48
Determination of intrinsic hydrophilicity/hydrophobicity of amino acid side chains in peptides in the absence of nearest-neighbor or conformational effects. Biopolymers (2006) 1.46
Antimicrobial peptide therapeutics for cystic fibrosis. Antimicrob Agents Chemother (2005) 1.44
The human cationic peptide LL-37 induces activation of the extracellular signal-regulated kinase and p38 kinase pathways in primary human monocytes. J Immunol (2004) 1.41
Intracellular receptor for human host defense peptide LL-37 in monocytes. J Immunol (2009) 1.38
Enhanced inflammatory responses of chronic granulomatous disease leukocytes involve ROS-independent activation of NF-kappa B. Eur J Immunol (2007) 1.37
Host defense peptide LL-37, in synergy with inflammatory mediator IL-1beta, augments immune responses by multiple pathways. J Immunol (2007) 1.37
The commensal Streptococcus salivarius K12 downregulates the innate immune responses of human epithelial cells and promotes host-microbe homeostasis. Infect Immun (2008) 1.36
Genetic determinants involved in the susceptibility of Pseudomonas aeruginosa to beta-lactam antibiotics. Antimicrob Agents Chemother (2010) 1.35
Cationic peptides: distribution and mechanisms of resistance. Curr Pharm Des (2002) 1.35
Enabling a systems biology approach to immunology: focus on innate immunity. Trends Immunol (2009) 1.35
Secondary acylation of Klebsiella pneumoniae lipopolysaccharide contributes to sensitivity to antibacterial peptides. J Biol Chem (2007) 1.33
Use of artificial intelligence in the design of small peptide antibiotics effective against a broad spectrum of highly antibiotic-resistant superbugs. ACS Chem Biol (2009) 1.33
Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment. J Immunol (2010) 1.32
Curating the innate immunity interactome. BMC Syst Biol (2010) 1.30
A novel class of microbial phosphocholine-specific phospholipases C. Mol Microbiol (2002) 1.30