Published in J Biol Chem on March 02, 2004
Identification of a novel coronavirus in bats. J Virol (2005) 3.48
The spike protein of SARS-CoV--a target for vaccine and therapeutic development. Nat Rev Microbiol (2009) 2.23
Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection. Clin Microbiol Rev (2007) 1.68
Inhibiting HIV fusion with a beta-peptide foldamer. J Am Chem Soc (2005) 1.55
Supramolecular architecture of severe acute respiratory syndrome coronavirus revealed by electron cryomicroscopy. J Virol (2006) 1.34
Recombinant receptor-binding domain of SARS-CoV spike protein expressed in mammalian, insect and E. coli cells elicits potent neutralizing antibody and protective immunity. Virology (2009) 1.22
Identification of two neutralizing regions on the severe acute respiratory syndrome coronavirus spike glycoprotein produced from the mammalian expression system. J Virol (2005) 1.21
Peptide nanoparticles as novel immunogens: design and analysis of a prototypic severe acute respiratory syndrome vaccine. Chem Biol Drug Des (2009) 1.18
Ready, set, fuse! The coronavirus spike protein and acquisition of fusion competence. Viruses (2012) 1.18
Identification and characterization of the putative fusion peptide of the severe acute respiratory syndrome-associated coronavirus spike protein. J Virol (2005) 1.16
Structural characterization of the fusion-active complex of severe acute respiratory syndrome (SARS) coronavirus. Proc Natl Acad Sci U S A (2004) 1.12
Specific asparagine-linked glycosylation sites are critical for DC-SIGN- and L-SIGN-mediated severe acute respiratory syndrome coronavirus entry. J Virol (2007) 1.06
SARS molecular epidemiology: a Chinese fairy tale of controlling an emerging zoonotic disease in the genomics era. Philos Trans R Soc Lond B Biol Sci (2007) 1.03
In vitro selection and characterization of HIV-1 variants with increased resistance to sifuvirtide, a novel HIV-1 fusion inhibitor. J Biol Chem (2010) 1.03
The cholera toxin A1(3) subdomain is essential for interaction with ADP-ribosylation factor 6 and full toxic activity but is not required for translocation from the endoplasmic reticulum to the cytosol. Infect Immun (2006) 1.02
Antigenic and immunogenic characterization of recombinant baculovirus-expressed severe acute respiratory syndrome coronavirus spike protein: implication for vaccine design. J Virol (2006) 1.02
Identification of a new region of SARS-CoV S protein critical for viral entry. J Mol Biol (2009) 0.95
A general strategy to endow natural fusion-protein-derived peptides with potent antiviral activity. PLoS One (2012) 0.94
A recombinant avian infectious bronchitis virus expressing a heterologous spike gene belonging to the 4/91 serotype. PLoS One (2011) 0.93
Human monoclonal antibodies against highly conserved HR1 and HR2 domains of the SARS-CoV spike protein are more broadly neutralizing. PLoS One (2012) 0.93
Novel inhibitors of severe acute respiratory syndrome coronavirus entry that act by three distinct mechanisms. J Virol (2013) 0.93
SARS vaccine development. Emerg Infect Dis (2005) 0.90
Role of spike protein endodomains in regulating coronavirus entry. J Biol Chem (2009) 0.89
A single native ganglioside GM1-binding site is sufficient for cholera toxin to bind to cells and complete the intoxication pathway. MBio (2012) 0.89
Functional characterization of heptad repeat 1 and 2 mutants of the spike protein of severe acute respiratory syndrome coronavirus. J Virol (2006) 0.88
Inhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein. Virus Res (2006) 0.88
Identification of N-linked carbohydrates from severe acute respiratory syndrome (SARS) spike glycoprotein. Virology (2010) 0.87
Identification of a unique "stability control region" that controls protein stability of tropomyosin: A two-stranded alpha-helical coiled-coil. J Mol Biol (2009) 0.87
Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I. fusion [corrected] inhibition. Biochem Biophys Res Commun (2007) 0.86
Contributions of the viral genetic background and a single amino acid substitution in an immunodominant CD8+ T-cell epitope to murine coronavirus neurovirulence. J Virol (2005) 0.85
Neutralizing human monoclonal antibodies to severe acute respiratory syndrome coronavirus: target, mechanism of action, and therapeutic potential. Rev Med Virol (2011) 0.83
Molecular mechanisms of severe acute respiratory syndrome (SARS). Respir Res (2005) 0.81
Antiviral drugs specific for coronaviruses in preclinical development. Curr Opin Virol (2014) 0.80
Substitution at aspartic acid 1128 in the SARS coronavirus spike glycoprotein mediates escape from a S2 domain-targeting neutralizing monoclonal antibody. PLoS One (2014) 0.79
SARS-CoV heptad repeat 2 is a trimer of parallel helices. Protein Sci (2011) 0.76
Modification of the avian coronavirus infectious bronchitis virus for vaccine development. Bioeng Bugs (2012) 0.76
The chromosomal nature of LT-II enterotoxins solved: a lambdoid prophage encodes both LT-II and one of two novel pertussis-toxin-like toxin family members in type II enterotoxigenic Escherichia coli. Pathog Dis (2016) 0.75
Development of Small-molecule HIV Entry Inhibitors Specifically Targeting gp120 or gp41. Curr Top Med Chem (2016) 0.75
Bats: important reservoir hosts of emerging viruses. Clin Microbiol Rev (2006) 8.77
CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus. Proc Natl Acad Sci U S A (2004) 2.38
Rational design of alpha-helical antimicrobial peptides with enhanced activities and specificity/therapeutic index. J Biol Chem (2005) 2.28
Detection of group 1 coronaviruses in bats in North America. Emerg Infect Dis (2007) 2.24
Gangliosides that associate with lipid rafts mediate transport of cholera and related toxins from the plasma membrane to endoplasmic reticulm. Mol Biol Cell (2003) 2.22
Global distribution of novel rhinovirus genotype. Emerg Infect Dis (2008) 2.03
Role of peptide hydrophobicity in the mechanism of action of alpha-helical antimicrobial peptides. Antimicrob Agents Chemother (2006) 1.87
Blinded case-control study of the relationship between human coronavirus NL63 and Kawasaki syndrome. J Infect Dis (2006) 1.81
Conformational changes in the spike glycoprotein of murine coronavirus are induced at 37 degrees C either by soluble murine CEACAM1 receptors or by pH 8. J Virol (2003) 1.79
LINE-1 retrotransposition requires the nucleic acid chaperone activity of the ORF1 protein. J Mol Biol (2005) 1.78
Multiplex MassTag-PCR for respiratory pathogens in pediatric nasopharyngeal washes negative by conventional diagnostic testing shows a high prevalence of viruses belonging to a newly recognized rhinovirus clade. J Clin Virol (2008) 1.69
Structural basis for the activation of cholera toxin by human ARF6-GTP. Science (2005) 1.66
Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor. Proc Natl Acad Sci U S A (2011) 1.65
Identification of a receptor-binding domain of the spike glycoprotein of human coronavirus HCoV-229E. J Virol (2003) 1.57
Effects of net charge and the number of positively charged residues on the biological activity of amphipathic alpha-helical cationic antimicrobial peptides. Biopolymers (2008) 1.51
Determination of intrinsic hydrophilicity/hydrophobicity of amino acid side chains in peptides in the absence of nearest-neighbor or conformational effects. Biopolymers (2006) 1.46
Crystal structure of murine sCEACAM1a[1,4]: a coronavirus receptor in the CEA family. EMBO J (2002) 1.37
Cellular internalization of cytolethal distending toxin: a new end to a known pathway. Cell Microbiol (2005) 1.32
The Pseudomonas aeruginosa type IV pilin receptor binding domain functions as an adhesin for both biotic and abiotic surfaces. Mol Microbiol (2006) 1.26
An allelic exchange system for compliant genetic manipulation of the select agents Burkholderia pseudomallei and Burkholderia mallei. Gene (2008) 1.26
The N-terminal domain of the murine coronavirus spike glycoprotein determines the CEACAM1 receptor specificity of the virus strain. J Virol (2003) 1.26
Identification of a DtxR-regulated operon that is essential for siderophore-dependent iron uptake in Corynebacterium diphtheriae. J Bacteriol (2002) 1.25
Designing heterodimeric two-stranded alpha-helical coiled-coils. Effects of hydrophobicity and alpha-helical propensity on protein folding, stability, and specificity. J Biol Chem (2002) 1.23
Detection of four human coronaviruses in respiratory infections in children: a one-year study in Colorado. J Med Virol (2009) 1.23
Conformational instability of the cholera toxin A1 polypeptide. J Mol Biol (2007) 1.22
Transfer of the cholera toxin A1 polypeptide from the endoplasmic reticulum to the cytosol is a rapid process facilitated by the endoplasmic reticulum-associated degradation pathway. Infect Immun (2002) 1.21
A novel method to measure self-association of small amphipathic molecules: temperature profiling in reversed-phase chromatography. J Biol Chem (2003) 1.21
Comparison of biophysical and biologic properties of alpha-helical enantiomeric antimicrobial peptides. Chem Biol Drug Des (2006) 1.20
Attenuated endocytosis and toxicity of a mutant cholera toxin with decreased ability to cluster ganglioside GM1 molecules. Infect Immun (2008) 1.20
Role of the spike glycoprotein of human Middle East respiratory syndrome coronavirus (MERS-CoV) in virus entry and syncytia formation. PLoS One (2013) 1.19
Human coronavirus 229E: receptor binding domain and neutralization by soluble receptor at 37 degrees C. J Virol (2003) 1.19
Peptide nanoparticles as novel immunogens: design and analysis of a prototypic severe acute respiratory syndrome vaccine. Chem Biol Drug Des (2009) 1.18
Activation-induced expression of carcinoembryonic antigen-cell adhesion molecule 1 regulates mouse T lymphocyte function. J Immunol (2002) 1.17
Crystal structure of bovine coronavirus spike protein lectin domain. J Biol Chem (2012) 1.16
Molecular characterization of Rab11-FIP3 binding to ARF GTPases. Eur J Cell Biol (2007) 1.14
Specific regulation of T helper cell 1-mediated murine colitis by CEACAM1. J Exp Med (2004) 1.14
Mutational analysis of aminopeptidase N, a receptor for several group 1 coronaviruses, identifies key determinants of viral host range. J Virol (2006) 1.13
Construction and characterization of transposon insertion mutations in Corynebacterium diphtheriae that affect expression of the diphtheria toxin repressor (DtxR). J Bacteriol (2002) 1.12
Ceacam1a-/- mice are completely resistant to infection by murine coronavirus mouse hepatitis virus A59. J Virol (2004) 1.12
Stabilizing and destabilizing clusters in the hydrophobic core of long two-stranded alpha-helical coiled-coils. J Biol Chem (2004) 1.12
Structural and functional studies on the interaction of GspC and GspD in the type II secretion system. PLoS Pathog (2011) 1.12
Counteracting roles of AMP deaminase and AMP kinase in the development of fatty liver. PLoS One (2012) 1.12
Characterization of mammalian Ecm29, a 26 S proteasome-associated protein that localizes to the nucleus and membrane vesicles. J Biol Chem (2004) 1.10
Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism. Biochemistry (2004) 1.09
SARS-CoV replicates in primary human alveolar type II cell cultures but not in type I-like cells. Virology (2007) 1.09
Structure-activity relationships of de novo designed cyclic antimicrobial peptides based on gramicidin S. Biopolymers (2003) 1.08
Optimization of microbial specificity in cyclic peptides by modulation of hydrophobicity within a defined structural framework. J Biol Chem (2001) 1.08
Probing the structural determinants of type II' beta-turn formation in peptides and proteins. J Am Chem Soc (2002) 1.08
CD13 is a novel mediator of monocytic/endothelial cell adhesion. J Leukoc Biol (2008) 1.07
Real-time monitoring of the interactions of two-stranded de novo designed coiled-coils: effect of chain length on the kinetic and thermodynamic constants of binding. Biochemistry (2003) 1.07
Temperature profiling of polypeptides in reversed-phase liquid chromatography. I. Monitoring of dimerization and unfolding of amphipathic alpha-helical peptides. J Chromatogr A (2003) 1.05
Temperature profiling of polypeptides in reversed-phase liquid chromatography. II. Monitoring of folding and stability of two-stranded alpha-helical coiled-coils. J Chromatogr A (2003) 1.04
Inhibition of endoplasmic reticulum-associated degradation in CHO cells resistant to cholera toxin, Pseudomonas aeruginosa exotoxin A, and ricin. Infect Immun (2002) 1.04
Temperature selectivity effects in reversed-phase liquid chromatography due to conformation differences between helical and non-helical peptides. J Chromatogr A (2003) 1.04
The cholera toxin A1(3) subdomain is essential for interaction with ADP-ribosylation factor 6 and full toxic activity but is not required for translocation from the endoplasmic reticulum to the cytosol. Infect Immun (2006) 1.02
Surface nanocrystallization of stainless steel for reduced biofilm adherence. Nanotechnology (2008) 1.02
Effect of variations in the structure of a polyleucine-based alpha-helical transmembrane peptide on its interaction with phosphatidylethanolamine Bilayers. Biophys J (2004) 1.02
Preparative reversed-phase high-performance liquid chromatography collection efficiency for an antimicrobial peptide on columns of varying diameters (1mm to 9.4mm I.D.). J Chromatogr A (2006) 1.01
Functional studies of the Mycobacterium tuberculosis iron-dependent regulator. J Biol Chem (2004) 1.01
The spike glycoprotein of murine coronavirus MHV-JHM mediates receptor-independent infection and spread in the central nervous systems of Ceacam1a-/- Mice. J Virol (2007) 1.01
Effect of variations in the structure of a polyleucine-based alpha-helical transmembrane peptide on its interaction with phosphatidylcholine bilayers. Biochemistry (2002) 1.01
Crystal structure of an IdeR-DNA complex reveals a conformational change in activated IdeR for base-specific interactions. J Mol Biol (2004) 1.01
Capillary electrophoresis of cationic random coil peptide standards: effect of anionic ion-pairing reagents and comparison with reversed-phase chromatography. Electrophoresis (2004) 1.01
Bacteriophage-based vectors for site-specific insertion of DNA in the chromosome of Corynebacteria. Gene (2006) 1.01
Clustering of large hydrophobes in the hydrophobic core of two-stranded alpha-helical coiled-coils controls protein folding and stability. J Biol Chem (2003) 1.00
Helix capping interactions stabilize the N-terminus of the kinesin neck coiled-coil. J Struct Biol (2002) 1.00
Clavatadine A, a natural product with selective recognition and irreversible inhibition of factor XIa. J Med Chem (2008) 0.99
Role of Ceacam1 in VEGF induced vasculogenesis of murine embryonic stem cell-derived embryoid bodies in 3D culture. Exp Cell Res (2009) 0.98
Isothermal titration calorimetry studies of the binding of a rationally designed analogue of the antimicrobial peptide gramicidin s to phospholipid bilayer membranes. Biochemistry (2005) 0.98
Antigen-specific memory T cell responses after vaccination with an oral killed cholera vaccine in Bangladeshi children and comparison to responses in patients with naturally acquired cholera. Clin Vaccine Immunol (2012) 0.98
The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction. Immunity (2012) 0.97
Analysis of genes that encode DtxR-like transcriptional regulators in pathogenic and saprophytic corynebacterial species. Infect Immun (2004) 0.97
The N-terminal region of the murine coronavirus spike glycoprotein is associated with the extended host range of viruses from persistently infected murine cells. J Virol (2004) 0.96
Alphacoronaviruses in New World bats: prevalence, persistence, phylogeny, and potential for interaction with humans. PLoS One (2011) 0.96
Crystal structures, metal activation, and DNA-binding properties of two-domain IdeR from Mycobacterium tuberculosis. Biochemistry (2007) 0.95
Amino acid substitutions and an insertion in the spike glycoprotein extend the host range of the murine coronavirus MHV-A59. Virology (2004) 0.94
Clavatadines C-E, guanidine alkaloids from the Australian sponge Suberea clavata. J Nat Prod (2009) 0.94
Regulation of the amino-terminal transcription activation domain of progesterone receptor by a cofactor-induced protein folding mechanism. Mol Cell Biol (2005) 0.93
Contribution of subdomain structure to the thermal stability of the cholera toxin A1 subunit. Biochemistry (2010) 0.93
Fourier transform infrared spectroscopic study of the interactions of a strongly antimicrobial but weakly hemolytic analogue of gramicidin S with lipid micelles and lipid bilayer membranes. Biochemistry (2003) 0.93
Receptor-dependent coronavirus infection of dendritic cells. J Virol (2004) 0.93
Effect of ring size on conformation and biological activity of cyclic cationic antimicrobial peptides. J Med Chem (2009) 0.93
A de novo designed template for generating conformation-specific antibodies that recognize alpha-helices in proteins. J Biol Chem (2002) 0.92
Tracking membrane protein association in model membranes. PLoS One (2009) 0.92
Synthetic peptide vaccine and antibody therapeutic development: prevention and treatment of Pseudomonas aeruginosa. Biopolymers (2003) 0.92
Defining the minimum size of a hydrophobic cluster in two-stranded alpha-helical coiled-coils: effects on protein stability. Protein Sci (2004) 0.92
Transcription of the contiguous sigB, dtxR, and galE genes in Corynebacterium diphtheriae: evidence for multiple transcripts and regulation by environmental factors. J Bacteriol (2006) 0.92
Interaction of gramicidin S and its aromatic amino-acid analog with phospholipid membranes. Biophys J (2008) 0.91
Effects of hydrophobicity on the antifungal activity of alpha-helical antimicrobial peptides. Chem Biol Drug Des (2008) 0.91
Expression of the mouse hepatitis virus receptor by central nervous system microglia. J Virol (2004) 0.91
Isothermal titration calorimetry studies of the binding of the antimicrobial peptide gramicidin S to phospholipid bilayer membranes. Biochemistry (2005) 0.91
Vesicular transport is not required for the cytoplasmic pool of cholera toxin to interact with the stimulatory alpha subunit of the heterotrimeric g protein. Infect Immun (2004) 0.90
Unique stabilizing interactions identified in the two-stranded alpha-helical coiled-coil: crystal structure of a cortexillin I/GCN4 hybrid coiled-coil peptide. Protein Sci (2003) 0.90
The role of unstructured highly charged regions on the stability and specificity of dimerization of two-stranded alpha-helical coiled-coils: analysis of the neck-hinge region of the kinesin-like motor protein Kif3A. J Struct Biol (2002) 0.90