Published in J Biol Chem on November 08, 2002
Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality. J Exp Med (2006) 2.75
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The role of angiogenic factors in predicting clinical outcome in severe bacterial infection in Malawian children. Crit Care (2010) 1.62
Density enhanced phosphatase-1 down-regulates urokinase receptor surface expression in confluent endothelial cells. Blood (2011) 1.57
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Antiangiogenic antitumor activities of IGFBP-3 are mediated by IGF-independent suppression of Erk1/2 activation and Egr-1-mediated transcriptional events. Blood (2011) 0.96
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Prostaglandin F2alpha stimulates the expression and secretion of transforming growth factor B1 via induction of the early growth response 1 gene (EGR1) in the bovine corpus luteum. Mol Endocrinol (2007) 0.92
Elevated levels of vascular endothelial growth factor (VEGF) and soluble vascular endothelial growth factor receptor (VEGFR)-2 in human malaria. Am J Trop Med Hyg (2010) 0.84
Early growth response protein 1 acts as an activator of SOX18 promoter. Exp Mol Med (2010) 0.82
Pentadecapeptide BPC 157 Reduces Bleeding and Thrombocytopenia after Amputation in Rats Treated with Heparin, Warfarin, L-NAME and L-Arginine. PLoS One (2015) 0.81
Loss of transcription factor early growth response gene 1 results in impaired endochondral bone repair. Bone (2011) 0.80
Egr-1 upregulates Siva-1 expression and induces cardiac fibroblast apoptosis. Int J Mol Sci (2014) 0.79
Time course analysis of gene expression identifies multiple genes with differential expression in patients with in-stent restenosis. BMC Med Genomics (2011) 0.77
Expression Pattern of Early Growth Response Gene 1 during Olive Flounder (Paralichthys olivaceus) Embryonic Development. Balsaenggwa Saengsig (2014) 0.75
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Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent. J Exp Med (2006) 3.65
An angiogenic role for the human peptide antibiotic LL-37/hCAP-18. J Clin Invest (2003) 3.19
Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases. J Biol Chem (2003) 2.52
Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia. Blood (2003) 2.20
Apoptotic cell clearance by bronchial epithelial cells critically influences airway inflammation. Nature (2012) 2.18
Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice. Cancer Res (2004) 2.12
Sphingosine kinase type 2 is essential for lymphopenia induced by the immunomodulatory drug FTY720. Blood (2005) 2.07
Protective role of phospholipid oxidation products in endotoxin-induced tissue damage. Nature (2002) 2.06
Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation. Blood (2010) 2.04
Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2. Circ Res (2010) 2.04
Signaling molecules of the NF-kappa B pathway shuttle constitutively between cytoplasm and nucleus. J Biol Chem (2002) 2.03
Blood monocyte concentration is critical for enhancement of collateral artery growth. Am J Physiol Heart Circ Physiol (2002) 1.99
Constant darkness induces IL-6-dependent depression-like behavior through the NF-κB signaling pathway. J Neurosci (2011) 1.96
Oxidized phospholipids stimulate angiogenesis via autocrine mechanisms, implicating a novel role for lipid oxidation in the evolution of atherosclerotic lesions. Circ Res (2006) 1.84
VEGFR-1-selective VEGF homologue PlGF is arteriogenic: evidence for a monocyte-mediated mechanism. Circ Res (2003) 1.82
Multi-hit inhibition of circulating and cell-associated components of the toll-like receptor 4 pathway by oxidized phospholipids. Arterioscler Thromb Vasc Biol (2008) 1.76
Cellular origins and thrombogenic activity of microparticles isolated from human atherosclerotic plaques. J Am Coll Cardiol (2007) 1.72
Identification of patients at low risk for recurrent venous thromboembolism by measuring thrombin generation. JAMA (2006) 1.72
Colony-stimulating factor-1 antibody reverses chemoresistance in human MCF-7 breast cancer xenografts. Cancer Res (2006) 1.67
Oxidized membrane vesicles and blebs from apoptotic cells contain biologically active oxidized phospholipids that induce monocyte-endothelial interactions. Arterioscler Thromb Vasc Biol (2002) 1.62
Knockdown of filaggrin impairs diffusion barrier function and increases UV sensitivity in a human skin model. J Invest Dermatol (2010) 1.59
Density enhanced phosphatase-1 down-regulates urokinase receptor surface expression in confluent endothelial cells. Blood (2011) 1.57
Oxidized phospholipids stimulate tissue factor expression in human endothelial cells via activation of ERK/EGR-1 and Ca(++)/NFAT. Blood (2002) 1.50
Oxidized phospholipids induce expression of human heme oxygenase-1 involving activation of cAMP-responsive element-binding protein. J Biol Chem (2003) 1.49
p38 MAP kinase--a molecular switch between VEGF-induced angiogenesis and vascular hyperpermeability. FASEB J (2002) 1.46
Premature senescence of highly proliferative endothelial progenitor cells is induced by tumor necrosis factor-alpha via the p38 mitogen-activated protein kinase pathway. FASEB J (2009) 1.45
Expression of heme oxygenase-1 in human vascular cells is regulated by peroxisome proliferator-activated receptors. Arterioscler Thromb Vasc Biol (2007) 1.45
FTY720 rescue therapy in the dark agouti rat model of experimental autoimmune encephalomyelitis: expression of central nervous system genes and reversal of blood-brain-barrier damage. Brain Pathol (2008) 1.45
Cardiac malformations and myocardial abnormalities in podoplanin knockout mouse embryos: Correlation with abnormal epicardial development. Dev Dyn (2008) 1.43
Matrix metalloproteases and their tissue inhibitor in cardiac transplantation. Eur J Cardiothorac Surg (2007) 1.41
Dimethylfumarate inhibits TNF-induced nuclear entry of NF-kappa B/p65 in human endothelial cells. J Immunol (2002) 1.39
Basal and induced sphingosine kinase 1 activity in A549 carcinoma cells: function in cell survival and IL-1beta and TNF-alpha induced production of inflammatory mediators. Cell Signal (2005) 1.39
Gabexate mesilate, a synthetic anticoagulant, inhibits the expression of endothelial leukocyte adhesion molecules in vitro. Crit Care Med (2003) 1.38
IFATS collection: Adipose stromal cell differentiation is reduced by endothelial cell contact and paracrine communication: role of canonical Wnt signaling. Stem Cells (2008) 1.32
Plasminogen activator inhibitor 1: physiological and pathophysiological roles. News Physiol Sci (2002) 1.30
Oxidized phospholipids regulate expression of ATF4 and VEGF in endothelial cells via NRF2-dependent mechanism: novel point of convergence between electrophilic and unfolded protein stress pathways. Arterioscler Thromb Vasc Biol (2010) 1.29
Oxidized phospholipids trigger atherogenic inflammation in murine arteries. Arterioscler Thromb Vasc Biol (2004) 1.29
Antiinflammatory activity of astragaloside IV is mediated by inhibition of NF-kappaB activation and adhesion molecule expression. Thromb Haemost (2003) 1.27
12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis. J Immunol (2009) 1.27
Colony-stimulating factor-1 antisense treatment suppresses growth of human tumor xenografts in mice. Cancer Res (2002) 1.22
Circulating vascular progenitor cells do not contribute to compensatory lung growth. Circ Res (2003) 1.21
Indirubin-3'-monoxime blocks vascular smooth muscle cell proliferation by inhibition of signal transducer and activator of transcription 3 signaling and reduces neointima formation in vivo. Arterioscler Thromb Vasc Biol (2010) 1.20
The VEGF-induced transcriptional response comprises gene clusters at the crossroad of angiogenesis and inflammation. Thromb Haemost (2009) 1.18
Oxidized phospholipids negatively regulate dendritic cell maturation induced by TLRs and CD40. J Immunol (2005) 1.18
Continuous endothelial cell activation increases angiogenesis: evidence for the direct role of endothelium linking angiogenesis and inflammation. J Vasc Res (2006) 1.17
Sustained expression of early growth response protein-1 blocks angiogenesis and tumor growth. Cancer Res (2006) 1.17
Vascular endothelial growth factor receptor-2-induced initial endothelial cell migration depends on the presence of the urokinase receptor. Circ Res (2004) 1.14
Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation. Exp Hematol (2008) 1.13
NF-E2-related factor 2 regulates the stress response to UVA-1-oxidized phospholipids in skin cells. FASEB J (2009) 1.13
Myeloid PTEN promotes inflammation but impairs bactericidal activities during murine pneumococcal pneumonia. J Immunol (2010) 1.11
Analysis of inflammatory gene induction by oxidized phospholipids in vivo by quantitative real-time RT-PCR in comparison with effects of LPS. Vascul Pharmacol (2002) 1.10
Vascular endothelial growth factor (VEGF) induces rapid prourokinase (pro-uPA) activation on the surface of endothelial cells. Blood (2003) 1.10
Early activation of sphingosine kinase in mast cells and recruitment to FcepsilonRI are mediated by its interaction with Lyn kinase. Mol Cell Biol (2004) 1.09
Direct binding of Nur77/NAK-1 to the plasminogen activator inhibitor 1 (PAI-1) promoter regulates TNF alpha -induced PAI-1 expression. Blood (2002) 1.08
Recent advances in the genetic analysis of PTEN and PI3K innate immune properties. Immunobiology (2008) 1.08
Neutropenia with impaired immune response to Streptococcus pneumoniae in ceramide kinase-deficient mice. J Immunol (2008) 1.08
Deciphering regulatory patterns of inflammatory gene expression from interleukin-1-stimulated human endothelial cells. Arterioscler Thromb Vasc Biol (2004) 1.08
Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice. EMBO Mol Med (2014) 1.08
Characterization of a ceramide kinase-like protein. Biochim Biophys Acta (2005) 1.06
Simvastatin reduces the expression of adhesion molecules in circulating monocytes from hypercholesterolemic patients. Arterioscler Thromb Vasc Biol (2003) 1.06
C5a stimulates production of plasminogen activator inhibitor-1 in human mast cells and basophils. Blood (2002) 1.06
Oxidized phospholipids are more potent antagonists of lipopolysaccharide than inducers of inflammation. J Immunol (2010) 1.06
GMCSF activates NF-kappaB via direct interaction of the GMCSF receptor with IkappaB kinase beta. Blood (2003) 1.04
Molecular evidence of Anaplasma phagocytophilum in Ixodes ricinus ticks and wild animals in Austria. J Clin Microbiol (2004) 1.04
VIGR--a novel inducible adhesion family G-protein coupled receptor in endothelial cells. FEBS Lett (2004) 1.03
Podoplanin deficient mice show a RhoA-related hypoplasia of the sinus venosus myocardium including the sinoatrial node. Dev Dyn (2009) 1.03
Stromal cell-derived CSF-1 blockade prolongs xenograft survival of CSF-1-negative neuroblastoma. Int J Cancer (2010) 1.03
Flagellin is the principal inducer of the antimicrobial peptide S100A7c (psoriasin) in human epidermal keratinocytes exposed to Escherichia coli. FASEB J (2008) 1.03
Mannose 6-phosphate/insulin-like growth factor 2 receptor limits cell invasion by controlling alphaVbeta3 integrin expression and proteolytic processing of urokinase-type plasminogen activator receptor. Mol Biol Cell (2008) 1.03
Polymorphic membrane protein (PMP) 20 and PMP 21 of Chlamydia pneumoniae induce proinflammatory mediators in human endothelial cells in vitro by activation of the nuclear factor-kappaB pathway. J Infect Dis (2003) 1.02