Published in FASEB J on January 05, 2009
Fat tissue, aging, and cellular senescence. Aging Cell (2010) 3.34
Mechanisms of vascular aging: new perspectives. J Gerontol A Biol Sci Med Sci (2010) 2.24
Release of proinflammatory mediators and expression of proinflammatory adhesion molecules by endothelial progenitor cells. Am J Physiol Heart Circ Physiol (2009) 1.20
Polyphenols and aging. Curr Aging Sci (2010) 1.06
Adiponectin prevents diabetic premature senescence of endothelial progenitor cells and promotes endothelial repair by suppressing the p38 MAP kinase/p16INK4A signaling pathway. Diabetes (2010) 1.01
p38 MAPK and JNK antagonistically control senescence and cytoplasmic p16INK4A expression in doxorubicin-treated endothelial progenitor cells. PLoS One (2010) 0.98
RhoA-mediated signaling in Notch-induced senescence-like growth arrest and endothelial barrier dysfunction. Arterioscler Thromb Vasc Biol (2011) 0.97
Tumor necrosis factor alpha inhibits olfactory regeneration in a transgenic model of chronic rhinosinusitis-associated olfactory loss. Am J Rhinol Allergy (2011) 0.97
Endothelial progenitor cells enter the aging arena. Front Physiol (2012) 0.94
Inhibition of p38 MAPK attenuates ionizing radiation-induced hematopoietic cell senescence and residual bone marrow injury. Radiat Res (2011) 0.92
The interplay of inflammation and cardiovascular disease in systemic lupus erythematosus. Arthritis Res Ther (2011) 0.90
Genetic and clinical correlates of early-outgrowth colony-forming units. Circ Cardiovasc Genet (2011) 0.89
Circulating progenitor cells and vascular dysfunction in chronic obstructive pulmonary disease. PLoS One (2014) 0.86
Geroconversion of aged muscle stem cells under regenerative pressure. Cell Cycle (2014) 0.86
Senescence, apoptosis, and stem cell biology: the rationale for an expanded view of intracrine action. Am J Physiol Heart Circ Physiol (2009) 0.85
Pentoxifylline reduces tumor necrosis factor-α and HIV-induced vascular endothelial activation. AIDS Res Hum Retroviruses (2012) 0.84
Tumor necrosis factor alpha promotes the proliferation of human nucleus pulposus cells via nuclear factor-κB, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase. Exp Biol Med (Maywood) (2014) 0.84
Sublethal heat shock induces premature senescence rather than apoptosis in human mesenchymal stem cells. Cell Stress Chaperones (2014) 0.83
Senescent vs. non-senescent cells in the human annulus in vivo: cell harvest with laser capture microdissection and gene expression studies with microarray analysis. BMC Biotechnol (2010) 0.83
Association of colony-forming units with coronary artery and abdominal aortic calcification. Circulation (2010) 0.83
Tetraspanin Family Member, CD82, Regulates Expression of EZH2 via Inactivation of p38 MAPK Signaling in Leukemia Cells. PLoS One (2015) 0.82
Long-Term Expansion in Platelet Lysate Increases Growth of Peripheral Blood-Derived Endothelial-Colony Forming Cells and Their Growth Factor-Induced Sprouting Capacity. PLoS One (2015) 0.82
In vitro functional testing of endothelial progenitor cells that overexpress thrombomodulin. Tissue Eng Part A (2011) 0.81
Translational control of PML contributes to TNFα-induced apoptosis of MCF7 breast cancer cells and decreased angiogenesis in HUVECs. Cell Death Differ (2015) 0.81
The functions of endothelial progenitor cells were significantly improved after treatment with intravenous immunoglobulin and aspirin in children with Kawasaki disease. Pediatr Cardiol (2011) 0.79
Chipping away at the surface of the endothelial progenitor cell (EPC) mystery. J Mol Med (Berl) (2011) 0.79
Ovarian aging-like phenotype in the hyperandrogenism-induced murine model of polycystic ovary. Oxid Med Cell Longev (2014) 0.79
Feeling the elephant of cardiovascular cell therapy. Circulation (2010) 0.79
The endothelium abridges insulin resistance to premature aging. J Am Heart Assoc (2013) 0.79
Ageing induced vascular smooth muscle cell senescence in atherosclerosis. J Physiol (2015) 0.78
Circulating hematopoietic progenitor cells are decreased in COPD. COPD (2013) 0.78
17beta-estradiol Attenuates TNF-α-Induced Premature Senescence of Nucleus Pulposus Cells through Regulating the ROS/NF-κB Pathway. Int J Biol Sci (2017) 0.78
The impact of cerebrovascular aging on vascular cognitive impairment and dementia. Ageing Res Rev (2016) 0.77
Anti-TNF-α treatment modulates SASP and SASP-related microRNAs in endothelial cells and in circulating angiogenic cells. Oncotarget (2016) 0.77
Endogenous Transmembrane TNF-Alpha Protects Against Premature Senescence in Endothelial Colony Forming Cells. Circ Res (2016) 0.75
Effects of Aging on Kidney Graft Function, Oxidative Stress and Gene Expression after Kidney Transplantation. PLoS One (2013) 0.75
Premature senescence of endothelial cells upon chronic exposure to TNFα can be prevented by N-acetyl cysteine and plumericin. Sci Rep (2017) 0.75
Gene and cell therapies for the failing heart to prevent sudden arrhythmic death. Minerva Cardioangiol (2012) 0.75
Valsartan ameliorates ageing-induced aorta degeneration via angiotensin II type 1 receptor-mediated ERK activity. J Cell Mol Med (2014) 0.75
Epigenetic Regulation of Placenta-Specific 8 Contributes to Altered Function of Endothelial Colony-Forming Cells Exposed to Intrauterine Gestational Diabetes Mellitus. Diabetes (2015) 0.75
Tumor necrosis factor alpha derived from classically activated "M1" macrophages reduces interstitial cell of Cajal numbers. Neurogastroenterol Motil (2016) 0.75
BZLF1 Attenuates Transmission of Inflammatory Paracrine Senescence in Epstein-Barr Virus-Infected Cells by Downregulating Tumor Necrosis Factor Alpha. J Virol (2016) 0.75
Activation of Cell Surface Bound 20S Proteasome Inhibits Vascular Cell Growth and Arteriogenesis. Biomed Res Int (2015) 0.75
The inflammatory cytokine TNF-α promotes the premature senescence of rat nucleus pulposus cells via the PI3K/Akt signaling pathway. Sci Rep (2017) 0.75
Endothelial progenitor cells in peripheral blood may serve as a biological marker to predict severe acute pancreatitis. World J Gastroenterol (2017) 0.75
The p38 pathway, a major pleiotropic cascade that transduces stress and metastatic signals in endothelial cells. Oncotarget (2017) 0.75
Reduced proliferation of endothelial colony-forming cells in unprovoked venous thromboembolic disease as a consequence of endothelial dysfunction. PLoS One (2017) 0.75
A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci U S A (1995) 32.89
A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science (2007) 18.96
Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med (2003) 13.84
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a. Nature (2006) 9.20
Cellular senescence in cancer and aging. Cell (2007) 9.04
Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals. Blood (2006) 8.56
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med (2006) 7.62
Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors. Circulation (2003) 7.29
Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood. Blood (2004) 7.21
Adult bone marrow-derived cells for cardiac repair: a systematic review and meta-analysis. Arch Intern Med (2007) 6.68
Synergistic neovascularization by mixed transplantation of early endothelial progenitor cells and late outgrowth endothelial cells: the role of angiogenic cytokines and matrix metalloproteinases. Circulation (2005) 3.54
Vessel wall-derived endothelial cells rapidly proliferate because they contain a complete hierarchy of endothelial progenitor cells. Blood (2004) 2.76
Diverse origin and function of cells with endothelial phenotype obtained from adult human blood. Circ Res (2003) 2.50
Vascular cell senescence: contribution to atherosclerosis. Circ Res (2007) 2.32
Free radicals, mitochondria, and oxidized lipids: the emerging role in signal transduction in vascular cells. Circ Res (2006) 2.14
Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase. J Biol Chem (2000) 2.14
HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes. Circ Res (2003) 1.76
Nonradioactive detection of telomerase activity using the telomeric repeat amplification protocol. Nat Protoc (2006) 1.70
p38 mitogen-activated protein kinase downregulates endothelial progenitor cells. Circulation (2005) 1.47
Constitutive human telomerase reverse transcriptase expression enhances regenerative properties of endothelial progenitor cells. Circulation (2002) 1.43
Embryonic endothelial progenitor cells expressing a broad range of proangiogenic and remodeling factors enhance vascularization and tissue recovery in acute and chronic ischemia. FASEB J (2005) 1.33
Tumor necrosis factor-alpha downregulates endothelial nitric oxide synthase mRNA stability via translation elongation factor 1-alpha 1. Circ Res (2008) 1.24
p16(INK4a) inactivation is not required to immortalize human mammary epithelial cells. Oncogene (2002) 1.21
Contribution of p16INK4a and p21CIP1 pathways to induction of premature senescence of human endothelial cells: permissive role of p53. Am J Physiol Heart Circ Physiol (2005) 1.00
Divergent and convergent effects on gene expression and function in acute versus chronic endothelial activation. Physiol Genomics (2007) 0.96
Role of NF-kappaB and PI 3-kinase/Akt in TNF-alpha-induced cytotoxicity in microvascular endothelial cells. Am J Physiol Renal Physiol (2008) 0.90
Production of the endocannabinoids anandamide and 2-arachidonoylglycerol by endothelial progenitor cells. FEBS Lett (2007) 0.88
An inconvenient truth: recognizing individual differences in arteriogenesis. Circ Res (2008) 0.86
Outgrowing endothelial progenitor-derived cells display high sensitivity to angiogenesis modulators and delayed senescence. FEBS Lett (2007) 0.85
Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals. Blood (2006) 8.56
Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood. Blood (2004) 7.21
Assessing identity, phenotype, and fate of endothelial progenitor cells. Arterioscler Thromb Vasc Biol (2008) 4.07
Human CD34+AC133+VEGFR-2+ cells are not endothelial progenitor cells but distinct, primitive hematopoietic progenitors. Exp Hematol (2007) 3.42
An angiogenic role for the human peptide antibiotic LL-37/hCAP-18. J Clin Invest (2003) 3.19
The emergence of hematopoietic stem cells is initiated in the placental vasculature in the absence of circulation. Cell Stem Cell (2008) 3.09
CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo. Development (2003) 3.09
Biomechanical forces promote embryonic haematopoiesis. Nature (2009) 2.99
Endothelial progenitor cells: identity defined? J Cell Mol Med (2009) 2.96
Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow. Cell (2008) 2.84
Robust functional vascular network formation in vivo by cooperation of adipose progenitor and endothelial cells. Circ Res (2009) 2.80
Vessel wall-derived endothelial cells rapidly proliferate because they contain a complete hierarchy of endothelial progenitor cells. Blood (2004) 2.76
Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cells. Blood (2005) 2.72
BMP10 is essential for maintaining cardiac growth during murine cardiogenesis. Development (2004) 2.50
Periostin is required for maturation and extracellular matrix stabilization of noncardiomyocyte lineages of the heart. Circ Res (2008) 2.44
Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4. Blood (2004) 2.35
All primitive and definitive hematopoietic progenitor cells emerging before E10 in the mouse embryo are products of the yolk sac. Blood (2007) 2.31
Lung microvascular endothelium is enriched with progenitor cells that exhibit vasculogenic capacity. Am J Physiol Lung Cell Mol Physiol (2007) 2.21
Injury of the renal microvascular endothelium alters barrier function after ischemia. Am J Physiol Renal Physiol (2003) 2.19
Flow cytometric identification and functional characterization of immature and mature circulating endothelial cells. Arterioscler Thromb Vasc Biol (2012) 2.07
Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target. Circulation (2010) 2.06
Cell-type-specific responses to chemotherapeutics in breast cancer. Cancer Res (2004) 2.01
Blood monocyte concentration is critical for enhancement of collateral artery growth. Am J Physiol Heart Circ Physiol (2002) 1.99
Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial. Lancet Oncol (2012) 1.95
The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle. J Mol Med (Berl) (2009) 1.94
Circulating angiogenic precursors in idiopathic pulmonary arterial hypertension. Am J Pathol (2008) 1.90
Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/- mast cells. J Clin Invest (2003) 1.85
VEGFR-1-selective VEGF homologue PlGF is arteriogenic: evidence for a monocyte-mediated mechanism. Circ Res (2003) 1.82
Ontogeny of CD24 in the human kidney. Kidney Int (2010) 1.81
Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension. Circ Res (2012) 1.81
Autonomous murine T-cell progenitor production in the extra-embryonic yolk sac before HSC emergence. Blood (2012) 1.72
Adult murine bone marrow-derived very small embryonic-like stem cells differentiate into the hematopoietic lineage after coculture over OP9 stromal cells. Exp Hematol (2010) 1.63
Embryonic day 9 yolk sac and intra-embryonic hemogenic endothelium independently generate a B-1 and marginal zone progenitor lacking B-2 potential. Proc Natl Acad Sci U S A (2011) 1.55
p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics. Blood (2009) 1.53
Sonic hedgehog and retinoic acid synergistically promote sensory fate specification from bone marrow-derived pluripotent stem cells. Proc Natl Acad Sci U S A (2005) 1.50
Increased incidence of stent thrombosis in patients with cocaine use. Catheter Cardiovasc Interv (2007) 1.49
Roles of spleen and liver in development of the murine hematopoietic system. Exp Hematol (2002) 1.49
Extracellular matrix scaffolds are repopulated by bone marrow-derived cells in a mouse model of achilles tendon reconstruction. J Orthop Res (2006) 1.49
Checkpoint-apoptosis uncoupling in human and mouse embryonic stem cells: a source of karyotpic instability. Blood (2007) 1.48
Nf1+/- mast cells induce neurofibroma like phenotypes through secreted TGF-beta signaling. Hum Mol Genet (2006) 1.48
PECAM-1 is expressed on hematopoietic stem cells throughout ontogeny and identifies a population of erythroid progenitors. Blood (2004) 1.47
p38 MAP kinase--a molecular switch between VEGF-induced angiogenesis and vascular hyperpermeability. FASEB J (2002) 1.46
Suppression of hepatocyte growth factor production impairs the ability of adipose-derived stem cells to promote ischemic tissue revascularization. Stem Cells (2007) 1.45
Renal ontogeny in the rhesus monkey (Macaca mulatta) and directed differentiation of human embryonic stem cells towards kidney precursors. Differentiation (2009) 1.45
Alpha5beta1 integrin as a cellular coreceptor for human parvovirus B19: requirement of functional activation of beta1 integrin for viral entry. Blood (2003) 1.45
Blood island formation: longstanding observations and modern interpretations. Exp Hematol (2005) 1.44
Membrane and capillary components of lung diffusion and pro-angiogenic cells in infants. Eur Respir J (2013) 1.43
Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle. J Mol Med (Berl) (2011) 1.43
Endothelial progenitor cells: quo vadis? J Mol Cell Cardiol (2010) 1.41
Rac2 concentrations in umbilical cord neutrophils. Biol Neonate (2006) 1.39
Isolation and characterization of endothelial progenitor cells from human blood. Curr Protoc Stem Cell Biol (2008) 1.36
A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis. Blood (2003) 1.36
SIRT1 deficiency compromises mouse embryonic stem cell hematopoietic differentiation, and embryonic and adult hematopoiesis in the mouse. Blood (2010) 1.36
S100A12 mediates aortic wall remodeling and aortic aneurysm. Circ Res (2009) 1.36
NAB2, a corepressor of EGR-1, inhibits vascular endothelial growth factor-mediated gene induction and angiogenic responses of endothelial cells. J Biol Chem (2002) 1.35
Endothelial cells in the early murine yolk sac give rise to CD41-expressing hematopoietic cells. Stem Cells Dev (2005) 1.35
Definitive hematopoietic commitment within the embryonic vascular endothelial-cadherin(+) population. Exp Hematol (2002) 1.35
Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection. J Clin Invest (2011) 1.35
Clonogenic endothelial progenitor cells are sensitive to oxidative stress. Stem Cells (2006) 1.34
IFATS collection: Adipose stromal cell differentiation is reduced by endothelial cell contact and paracrine communication: role of canonical Wnt signaling. Stem Cells (2008) 1.32
Cord blood stem and progenitor cells. Methods Enzymol (2006) 1.29
Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis. Blood (2009) 1.29
Factors impacting human telomere homeostasis and age-related disease. Mech Ageing Dev (2007) 1.28
Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells. Blood (2008) 1.28
Endothelial colony-forming cell role in neoangiogenesis and tissue repair. Curr Opin Organ Transplant (2010) 1.27
Early pulmonary vascular disease in preterm infants at risk for bronchopulmonary dysplasia. Am J Respir Crit Care Med (2015) 1.26
Neurofibromin is a novel regulator of RAS-induced signals in primary vascular smooth muscle cells. Hum Mol Genet (2006) 1.24
Impaired nuclear transport and uncoating limit recombinant adeno-associated virus 2 vector-mediated transduction of primary murine hematopoietic cells. Hum Gene Ther (2004) 1.23
Ape1 regulates hematopoietic differentiation of embryonic stem cells through its redox functional domain. Blood (2006) 1.22
Application of polychromatic flow cytometry to identify novel subsets of circulating cells with angiogenic potential. Cytometry A (2010) 1.22
Critical roles of lysosomal acid lipase in myelopoiesis. Am J Pathol (2010) 1.22
Circulating vascular progenitor cells do not contribute to compensatory lung growth. Circ Res (2003) 1.21
Release of proinflammatory mediators and expression of proinflammatory adhesion molecules by endothelial progenitor cells. Am J Physiol Heart Circ Physiol (2009) 1.20
Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions. J Clin Invest (2006) 1.20
Bone marrow progenitor cells induce endothelial adherens junction integrity by sphingosine-1-phosphate-mediated Rac1 and Cdc42 signaling. Circ Res (2009) 1.19
Epigenetic regulation of NANOG by miR-302 cluster-MBD2 completes induced pluripotent stem cell reprogramming. Stem Cells (2013) 1.19
Endothelial abnormalities in adolescents with type 1 diabetes: a biomarker for vascular sequelae? J Pediatr (2010) 1.18
Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions. Mol Cell Biol (2008) 1.18
Continuous endothelial cell activation increases angiogenesis: evidence for the direct role of endothelium linking angiogenesis and inflammation. J Vasc Res (2006) 1.17
Telomere dysfunction in aging and cancer. Int J Biochem Cell Biol (2005) 1.17
Endothelial progenitor cell: ongoing controversy for defining these cells and their role in neoangiogenesis in the murine system. Curr Opin Hematol (2009) 1.17
Endothelial colony-forming cells from preterm infants are increased and more susceptible to hyperoxia. Am J Respir Crit Care Med (2009) 1.17
Sustained expression of early growth response protein-1 blocks angiogenesis and tumor growth. Cancer Res (2006) 1.17
Telomerase template antagonist GRN163L disrupts telomere maintenance, tumor growth, and metastasis of breast cancer. Clin Cancer Res (2006) 1.16
Hematopoietic stem cell repopulating ability can be maintained in vitro by some primary endothelial cells. Exp Hematol (2004) 1.16
Identification of endothelial cells and progenitor cell subsets in human peripheral blood. Curr Protoc Cytom (2010) 1.15
Bypass of telomere-dependent replicative senescence (M1) upon overexpression of Cdk4 in normal human epithelial cells. Oncogene (2003) 1.15
Neurofibromin plays a critical role in modulating osteoblast differentiation of mesenchymal stem/progenitor cells. Hum Mol Genet (2006) 1.15
Oxidative stress impairs endothelial progenitor cell function. Antioxid Redox Signal (2008) 1.15
Shared environmental factors associated with telomere length maintenance in elderly male twins. Aging Cell (2007) 1.14
Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation. Exp Hematol (2008) 1.13