Published in Chem Commun (Camb) on October 21, 2002
Integrin ligands at a glance. J Cell Sci (2006) 4.76
Vinculin controls focal adhesion formation by direct interactions with talin and actin. J Cell Biol (2007) 4.28
Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments. Dev Cell (2007) 3.84
Demonstration of catch bonds between an integrin and its ligand. J Cell Biol (2009) 3.26
Synergistic control of cell adhesion by integrins and syndecans. Nat Rev Mol Cell Biol (2007) 3.21
Integrin structure, activation, and interactions. Cold Spring Harb Perspect Biol (2011) 2.58
Syndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix. J Cell Biol (2007) 2.33
Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6. Sci Signal (2009) 2.26
Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells. PLoS Biol (2009) 2.16
Linking integrin conformation to function. J Cell Sci (2009) 2.15
Heparin-II domain of fibronectin is a vascular endothelial growth factor-binding domain: enhancement of VEGF biological activity by a singular growth factor/matrix protein synergism. Circ Res (2006) 2.08
SHARPIN is an endogenous inhibitor of β1-integrin activation. Nat Cell Biol (2011) 2.01
Integrin-specific signaling pathways controlling focal adhesion formation and cell migration. J Cell Biol (2003) 1.90
Fibronectin regulates latent transforming growth factor-beta (TGF beta) by controlling matrix assembly of latent TGF beta-binding protein-1. J Biol Chem (2005) 1.82
Structure of an integrin-ligand complex deduced from solution x-ray scattering and site-directed mutagenesis. J Biol Chem (2003) 1.81
Conformational changes in the integrin beta A domain provide a mechanism for signal transduction via hybrid domain movement. J Biol Chem (2003) 1.80
Anti-integrin monoclonal antibodies. J Cell Sci (2009) 1.72
Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain. J Biol Chem (2002) 1.65
Quantification of integrin receptor agonism by fluorescence lifetime imaging. J Cell Sci (2008) 1.64
Regulation of alpha5beta1 integrin conformation and function by urokinase receptor binding. J Cell Biol (2005) 1.44
A specific alpha5beta1-integrin conformation promotes directional integrin translocation and fibronectin matrix formation. J Cell Sci (2004) 1.42
p190RhoGAP is the convergence point of adhesion signals from alpha 5 beta 1 integrin and syndecan-4. J Cell Biol (2008) 1.41
Cytoplasmic interactions of syndecan-4 orchestrate adhesion receptor and growth factor receptor signalling. Biochem J (2002) 1.39
Regulation of integrin function through conformational complexity: not simply a knee-jerk reaction? Curr Opin Cell Biol (2004) 1.38
Role of ADMIDAS cation-binding site in ligand recognition by integrin alpha 5 beta 1. J Biol Chem (2003) 1.36
Site-directed perturbation of protein kinase C- integrin interaction blocks carcinoma cell chemotaxis. Mol Cell Biol (2002) 1.35
Cell adhesion to fibrillin-1 molecules and microfibrils is mediated by alpha 5 beta 1 and alpha v beta 3 integrins. J Biol Chem (2003) 1.32
A syndecan-4 hair trigger initiates wound healing through caveolin- and RhoG-regulated integrin endocytosis. Dev Cell (2011) 1.31
Evidence that monoclonal antibodies directed against the integrin beta subunit plexin/semaphorin/integrin domain stimulate function by inducing receptor extension. J Biol Chem (2004) 1.29
Focal adhesions are sites of integrin extension. J Cell Biol (2010) 1.26
Molecular interplay between endostatin, integrins, and heparan sulfate. J Biol Chem (2009) 1.25
Alpha v beta3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration. J Cell Biol (2010) 1.24
The integrins of the urochordate Ciona intestinalis provide novel insights into the molecular evolution of the vertebrate integrin family. BMC Evol Biol (2005) 1.23
Fibronectin-tissue transglutaminase matrix rescues RGD-impaired cell adhesion through syndecan-4 and beta1 integrin co-signaling. J Biol Chem (2008) 1.21
Four-coordinate iron complexes bearing alpha-diimine ligands: efficient catalysts for atom transfer radical polymerisation (ATRP). Chem Commun (Camb) (2002) 1.21
Giving off mixed signals--distinct functions of alpha5beta1 and alphavbeta3 integrins in regulating cell behaviour. IUBMB Life (2009) 1.14
Molecular basis for the dynamic strength of the integrin alpha4beta1/VCAM-1 interaction. Biophys J (2004) 1.14
RCP-driven α5β1 recycling suppresses Rac and promotes RhoA activity via the RacGAP1-IQGAP1 complex. J Cell Biol (2013) 1.13
Syndecan-4 phosphorylation is a control point for integrin recycling. Dev Cell (2013) 1.12
Cell adhesion to fibrillin-1: identification of an Arg-Gly-Asp-dependent synergy region and a heparin-binding site that regulates focal adhesion formation. J Cell Sci (2007) 1.08
Proteomic analysis of integrin adhesion complexes. Sci Signal (2011) 1.06
Interaction of filamin A with the integrin beta 7 cytoplasmic domain: role of alternative splicing and phosphorylation. FEBS Lett (2004) 1.05
Cyclic mechanical reinforcement of integrin-ligand interactions. Mol Cell (2013) 1.05
An integrin-alpha4-14-3-3zeta-paxillin ternary complex mediates localised Cdc42 activity and accelerates cell migration. J Cell Sci (2009) 1.04
Integrin alpha5beta1 and ADAM-17 interact in vitro and co-localize in migrating HeLa cells. J Biol Chem (2004) 1.03
Defining the extracellular matrix using proteomics. Int J Exp Pathol (2013) 1.03
Syndecans shed their reputation as inert molecules. Sci Signal (2009) 1.02
Proteomic analysis of extracellular matrix from the hepatic stellate cell line LX-2 identifies CYR61 and Wnt-5a as novel constituents of fibrotic liver. J Proteome Res (2012) 1.00
Preconditioning injury-induced neurite outgrowth of adult rat sensory neurons on fibronectin is mediated by mobilisation of axonal alpha5 integrin. Mol Cell Neurosci (2007) 1.00
Distinct roles of beta1 metal ion-dependent adhesion site (MIDAS), adjacent to MIDAS (ADMIDAS), and ligand-associated metal-binding site (LIMBS) cation-binding sites in ligand recognition by integrin alpha2beta1. J Biol Chem (2008) 1.00
Novel activating and inactivating mutations in the integrin beta1 subunit A domain. Biochem J (2004) 0.99
High activity ethylene trimerisation catalysts based on diphosphine ligands. Chem Commun (Camb) (2002) 0.99
Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment. Proteomics (2012) 0.98
Integrin-binding RGD peptides induce rapid intracellular calcium increases and MAPK signaling in cortical neurons. Mol Cell Neurosci (2006) 0.98
Rac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway. J Cell Sci (2013) 0.97
Role of adhesion receptor trafficking in 3D cell migration. Curr Opin Cell Biol (2013) 0.97
Divalent cations regulate the folding and activation status of integrins during their intracellular trafficking. J Cell Sci (2011) 0.96
E-cadherin is a ligand for integrin alpha2beta1. Matrix Biol (2002) 0.96
Dual functionality of the anti-beta1 integrin antibody, 12G10, exemplifies agonistic signalling from the ligand binding pocket of integrin adhesion receptors. J Biol Chem (2005) 0.96
Identification of multiple integrin beta1 homologs in zebrafish (Danio rerio). BMC Cell Biol (2006) 0.95
Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance. J Biol Chem (2013) 0.95
An unraveling tale of how integrins are activated from within. Trends Pharmacol Sci (2003) 0.95
Alternative splicing of the IIICS domain in fibronectin governs the role of the heparin II domain in fibrillogenesis and cell spreading. J Biol Chem (2002) 0.95
Integrins and syndecan-4 make distinct, but critical, contributions to adhesion contact formation. Soft Matter (2007) 0.95
Distinct biophysical mechanisms of focal adhesion kinase mechanoactivation by different extracellular matrix proteins. Proc Natl Acad Sci U S A (2013) 0.94
Therapeutic ultrasound bypasses canonical syndecan-4 signaling to activate rac1. J Biol Chem (2009) 0.92
A novel gain-of-function mutation of the integrin alpha2 VWFA domain. Eur J Biochem (2002) 0.92
Activation of beta 1 but not beta 3 integrin increases cell traction forces. FEBS Lett (2013) 0.92
Mapping the ligand-binding pocket of integrin alpha5beta1 using a gain-of-function approach. Biochem J (2009) 0.91
Frustrated Lewis pairs beyond the main group: cationic zirconocene-phosphinoaryloxide complexes and their application in catalytic dehydrogenation of amine boranes. J Am Chem Soc (2011) 0.87
Ligand effects in chromium diphosphine catalysed olefin co-trimerisation and diene trimerisation. Dalton Trans (2009) 0.85
Activation of integrin alpha5beta1 delays apoptosis of Ntera2 neuronal cells. Mol Cell Neurosci (2005) 0.85
Fibronectin supports neurite outgrowth and axonal regeneration of adult brain neurons in vitro. Brain Res (2012) 0.85
Alpha2(VIII) collagen substrata enhance endothelial cell retention under acute shear stress flow via an alpha2beta1 integrin-dependent mechanism: an in vitro and in vivo study. Circulation (2006) 0.85
CD14 is a ligand for the integrin alpha4beta1. FEBS Lett (2007) 0.84
Catalytic conversion of ethanol into an advanced biofuel: unprecedented selectivity for n-butanol. Angew Chem Int Ed Engl (2013) 0.83
Opticin exerts its anti-angiogenic activity by regulating extracellular matrix adhesiveness. J Biol Chem (2012) 0.83
Evidence for the presence of a low-mass beta1 integrin on the cell surface. J Cell Sci (2005) 0.83
Cell biology: adhesion articulated. Nature (2004) 0.82
Frustrated Lewis pairs beyond the main group: synthesis, reactivity, and small molecule activation with cationic zirconocene-phosphinoaryloxide complexes. J Am Chem Soc (2011) 0.82
The selective trimerisation of isoprene with chromium N,N-bis(diarylphosphino)amine catalysts. Chem Commun (Camb) (2007) 0.81
Isolation of integrin-based adhesion complexes. Curr Protoc Cell Biol (2015) 0.80
A small molecule alpha 4 beta 1 antagonist prevents development of murine Lyme arthritis without affecting protective immunity. J Immunol (2005) 0.80
Alternative cellular roles for proteins identified using proteomics. J Proteomics (2012) 0.79
Cationic Ti(IV) and neutral Ti(III) titanocene-phosphinoaryloxide frustrated Lewis pairs: hydrogen activation and catalytic amine-borane dehydrogenation. Dalton Trans (2012) 0.78
The effect of peptide adsorption on signal linearity and a simple approach to improve reliability of quantification. J Proteomics (2013) 0.78
New Cu(I)-ethylene complexes based on tridentate imine ligands: synthesis and structure. Inorg Chem (2013) 0.78
Synthesis and structural characterization of tin analogues of N-heterocyclic carbenes. Inorg Chem (2008) 0.78
Interaction of the α2A domain of integrin with small collagen fragments. Protein Cell (2010) 0.78
Cu(I) complexes based on cis, cis-1,3,5-tris(arylideneamino)cyclohexane ligands: synthesis, structure and CO binding. Dalton Trans (2010) 0.77
Generation of aminoborane monomers RR'N=BH2 from amine-boronium cations [RR'NH-BH2L](+): metal catalyst-free formation of polyaminoboranes at ambient temperature. Chem Commun (Camb) (2014) 0.77
A new class of remote N-heterocyclic carbenes with exceptionally strong σ-donor properties: introducing benzo[c]quinolin-6-ylidene. Chemistry (2013) 0.76
Cell-to-cell contact and extracellular matrix. Curr Opin Cell Biol (2009) 0.76
Calpha-H...O = C hydrogen bonds contribute to the specificity of RGD cell-adhesion interactions. BMC Struct Biol (2005) 0.76
The alternatively spliced type III connecting segment of fibronectin is a zinc-binding module. Matrix Biol (2007) 0.75
Cyclopropenylidene carbene ligands in palladium catalysed coupling reactions: carbene ligand rotation and application to the Stille reaction. Dalton Trans (2011) 0.75
One electron oxidation of chromium N,N-bis(diarylphosphino)amine and bis(diarylphosphino)methane complexes relevant to ethene trimerisation and tetramerisation. Dalton Trans (2007) 0.75
Catalytic conversion of methanol/ethanol to isobutanol - a highly selective route to an advanced biofuel. Chem Commun (Camb) (2016) 0.75
Bis(carbene)pyridine complexes of Cr(III): exceptionally active catalysts for the oligomerization of ethylene. J Am Chem Soc (2003) 0.75