PubRank

Hubert Laude

Author PubWeight™ 75.15‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cells release prions in association with exosomes. Proc Natl Acad Sci U S A 2004 5.17
2 A newly identified type of scrapie agent can naturally infect sheep with resistant PrP genotypes. Proc Natl Acad Sci U S A 2005 2.47
3 BSE agent signatures in a goat. Vet Rec 2005 2.35
4 Facilitated cross-species transmission of prions in extraneural tissue. Science 2012 2.26
5 Prion agent diversity and species barrier. Vet Res 2008 1.80
6 Identification of the epitope region capable of inducing neutralizing antibodies against the porcine epidemic diarrhea virus. Mol Cells 2002 1.77
7 A bovine prion acquires an epidemic bovine spongiform encephalopathy strain-like phenotype on interspecies transmission. J Neurosci 2007 1.75
8 The physical relationship between infectivity and prion protein aggregates is strain-dependent. PLoS Pathog 2010 1.59
9 Generation of a replication-competent, propagation-deficient virus vector based on the transmissible gastroenteritis coronavirus genome. J Virol 2002 1.57
10 Isolation from cattle of a prion strain distinct from that causing bovine spongiform encephalopathy. PLoS Pathog 2006 1.55
11 Sheep and goat BSE propagate more efficiently than cattle BSE in human PrP transgenic mice. PLoS Pathog 2011 1.38
12 Transmission of atypical bovine prions to mice transgenic for human prion protein. Emerg Infect Dis 2008 1.38
13 Transgenesis applied to transmissible spongiform encephalopathies. Transgenic Res 2002 1.38
14 Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death. Proc Natl Acad Sci U S A 2004 1.27
15 Atypical/Nor98 scrapie infectivity in sheep peripheral tissues. PLoS Pathog 2011 1.26
16 Exosomes: a bubble ride for prions? Traffic 2005 1.24
17 Prominent and persistent extraneural infection in human PrP transgenic mice infected with variant CJD. PLoS One 2008 1.24
18 Cultured peripheral neuroglial cells are highly permissive to sheep prion infection. J Virol 2004 1.19
19 Expression of prion protein increases cellular copper binding and antioxidant enzyme activities but not copper delivery. J Biol Chem 2002 1.15
20 Efficient dissemination of prions through preferential transmission to nearby cells. J Gen Virol 2007 1.15
21 Endogenous proteolytic cleavage of disease-associated prion protein to produce C2 fragments is strongly cell- and tissue-dependent. J Biol Chem 2010 1.14
22 Antihypertensive drug guanabenz is active in vivo against both yeast and mammalian prions. PLoS One 2008 1.13
23 Marked influence of the route of infection on prion strain apparent phenotype in a scrapie transgenic mouse model. Neurobiol Dis 2010 1.04
24 The prion or the related Shadoo protein is required for early mouse embryogenesis. FEBS Lett 2009 1.03
25 PrPc does not mediate internalization of PrPSc but is required at an early stage for de novo prion infection of Rov cells. J Virol 2007 1.01
26 PrPSc binding antibodies are potent inhibitors of prion replication in cell lines. J Biol Chem 2004 0.99
27 PrP polymorphisms tightly control sheep prion replication in cultured cells. J Virol 2003 0.99
28 Binding of transmissible gastroenteritis coronavirus to cell surface sialoglycoproteins. J Virol 2002 0.97
29 Use of murine bioassay to resolve ovine transmissible spongiform encephalopathy cases showing a bovine spongiform encephalopathy molecular profile. Brain Pathol 2011 0.95
30 Characterization of atypical scrapie cases from Great Britain in transgenic ovine PrP mice. J Gen Virol 2010 0.95
31 Infection of cell lines with experimental and natural ovine scrapie agents. J Virol 2009 0.95
32 Glycan-controlled epitopes of prion protein include a major determinant of susceptibility to sheep scrapie. J Virol 2004 0.92
33 Prion strain- and species-dependent effects of antiprion molecules in primary neuronal cultures. J Virol 2007 0.92
34 Glycoform-selective prion formation in sporadic and familial forms of prion disease. PLoS One 2013 0.91
35 Quaternary structure of pathological prion protein as a determining factor of strain-specific prion replication dynamics. PLoS Pathog 2013 0.90
36 Highly infectious prions generated by a single round of microplate-based protein misfolding cyclic amplification. MBio 2013 0.89
37 Prion propagation in cells expressing PrP glycosylation mutants. J Virol 2011 0.88
38 Transcriptomic analysis brings new insight into the biological role of the prion protein during mouse embryogenesis. PLoS One 2011 0.88
39 Infection by ME7 prion is not modified in transgenic mice expressing the yeast chaperone Hsp104 in neurons. Neurosci Lett 2006 0.88
40 Proteasome inhibitors promote the sequestration of PrPSc into aggresomes within the cytosol of prion-infected CAD neuronal cells. J Gen Virol 2009 0.87
41 Prion protein and Shadoo are involved in overlapping embryonic pathways and trophoblastic development. PLoS One 2012 0.87
42 Endogenous prion protein conversion is required for prion-induced neuritic alterations and neuronal death. FASEB J 2012 0.87
43 Atypical scrapie isolates involve a uniform prion species with a complex molecular signature. PLoS One 2011 0.87
44 Using budding yeast to screen for anti-prion drugs. Biotechnol J 2006 0.86
45 Scrg1 is induced in TSE and brain injuries, and associated with autophagy. Eur J Neurosci 2005 0.84
46 Prion infection of epithelial Rov cells is a polarized event. J Virol 2004 0.84
47 Brain transcriptional stability upon prion protein-encoding gene invalidation in zygotic or adult mouse. BMC Genomics 2010 0.84
48 Generation of Sprn-regulated reporter mice reveals gonadic spatial expression of the prion-like protein Shadoo in mice. Biochem Biophys Res Commun 2011 0.82
49 Identification of atypical scrapie in Canadian sheep. J Vet Diagn Invest 2010 0.82
50 Prions impair bioaminergic functions through serotonin- or catecholamine-derived neurotoxins in neuronal cells. J Biol Chem 2008 0.82
51 Integrity of helix 2-helix 3 domain of the PrP protein is not mandatory for prion replication. J Biol Chem 2012 0.82
52 SCRG1, a potential marker of autophagy in transmissible spongiform encephalopathies. Autophagy 2006 0.81
53 The sialic acid binding activity of the S protein facilitates infection by porcine transmissible gastroenteritis coronavirus. Virol J 2011 0.81
54 Characterization of spontaneously generated prion-like conformers in cultured cells. Aging (Albany NY) 2011 0.81
55 Glycosylation-related gene expression profiling in the brain and spleen of scrapie-affected mouse. Glycobiology 2009 0.80
56 Prnp knockdown in transgenic mice using RNA interference. Transgenic Res 2008 0.80
57 Plasminogen-based capture combined with amplification technology for the detection of PrP(TSE) in the pre-clinical phase of infection. PLoS One 2013 0.80
58 Glycan chains modulate prion protein binding to immobilized metal ions. Neurochem Int 2007 0.79
59 Targeted knock-down of cellular prion protein expression in myelinating Schwann cells does not alter mouse prion pathogenesis. J Gen Virol 2013 0.78
60 Expression of the prion-like protein Shadoo in the developing mouse embryo. Biochem Biophys Res Commun 2011 0.78
61 Decontamination of prions in a plasma product manufacturing environment. Transfusion 2013 0.77
62 [Exosomes: carriers of prions?]. Med Sci (Paris) 2005 0.77
63 In vitro infectivity assay for prion titration for application to the evaluation of the prion removal capacity of biological products manufacturing processes. J Virol Methods 2009 0.77
64 The prion protein family: looking outside the central nervous system. Prion 2012 0.77
65 Prion proteins from susceptible and resistant sheep exhibit some distinct cell biological features. Biochem Biophys Res Commun 2005 0.77
66 Mammalian prions: tolerance to sequence changes-how far? Prion 2012 0.76
67 Spatial and temporal down-regulation of transgene expression using the TRSID-silencer in mice: application to Prnp. FEBS Lett 2008 0.76
68 [Tissue-specific cross-species transmission of prions]. Med Sci (Paris) 2012 0.75
69 Variation in Chst8 gene expression level affects PrPC to PrPSc conversion efficiency in prion-infected Mov cells. Biochem Biophys Res Commun 2011 0.75
70 [Cell culture models of transmissible spongiform encephalopathies]. C R Biol 2002 0.75
71 Scratch-wounding renders cultivated cells less permissive to prion infection. Biochem Biophys Res Commun 2005 0.75