PubRank

Alan R Prescott

Author PubWeight™ 94.89‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm. EMBO J 2003 3.77
2 Enhanced dendritic cell antigen capture via toll-like receptor-induced actin remodeling. Science 2004 3.08
3 Essential role of PDK1 in regulating cell size and development in mice. EMBO J 2002 2.93
4 Molecular mechanisms of kinetochore capture by spindle microtubules. Nature 2005 2.90
5 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization. Biochem J 2010 2.82
6 Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome. Am J Hum Genet 2003 2.73
7 Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser(910)/Ser(935), disruption of 14-3-3 binding and altered cytoplasmic localization. Biochem J 2010 2.43
8 The in vivo role of PtdIns(3,4,5)P3 binding to PDK1 PH domain defined by knockin mutation. EMBO J 2004 2.11
9 Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKalpha2 but not AMPKalpha1. Am J Physiol Endocrinol Metab 2005 2.04
10 Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion. EMBO J 2002 1.83
11 Inhibition of autophagy in mitotic animal cells. Traffic 2002 1.81
12 Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates. EMBO J 2004 1.77
13 Regulation of activity and localization of the WNK1 protein kinase by hyperosmotic stress. J Cell Biol 2006 1.68
14 Analysis of the LKB1-STRAD-MO25 complex. J Cell Sci 2004 1.65
15 Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways. J Cell Sci 2011 1.55
16 TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNF alpha in LPS-stimulated macrophages. J Cell Sci 2008 1.52
17 Small molecule antagonists of the sigma-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo. Cancer Res 2004 1.49
18 14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK. J Cell Sci 2005 1.46
19 Proof that Burkholderia strains form effective symbioses with legumes: a study of novel Mimosa-nodulating strains from South America. Appl Environ Microbiol 2005 1.44
20 BslA is a self-assembling bacterial hydrophobin that coats the Bacillus subtilis biofilm. Proc Natl Acad Sci U S A 2013 1.44
21 Cajal body proteins SMN and Coilin show differential dynamic behaviour in vivo. J Cell Sci 2003 1.44
22 New roles for the LKB1-NUAK pathway in controlling myosin phosphatase complexes and cell adhesion. Sci Signal 2010 1.43
23 WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate. Biochem J 2004 1.43
24 The adenomatous polyposis coli protein unambiguously localizes to microtubule plus ends and is involved in establishing parallel arrays of microtubule bundles in highly polarized epithelial cells. J Cell Biol 2002 1.43
25 Altered aggregation properties of mutant gamma-crystallins cause inherited cataract. EMBO J 2002 1.35
26 The C terminus of lens aquaporin 0 interacts with the cytoskeletal proteins filensin and CP49. Invest Ophthalmol Vis Sci 2006 1.35
27 Nodulation of Mimosa spp. by the beta-proteobacterium Ralstonia taiwanensis. Mol Plant Microbe Interact 2003 1.31
28 Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects. J Allergy Clin Immunol 2013 1.30
29 The suppression of galactose metabolism in procylic form Trypanosoma brucei causes cessation of cell growth and alters procyclin glycoprotein structure and copy number. J Biol Chem 2005 1.30
30 The ubiquitin-associated domain of AMPK-related kinases regulates conformation and LKB1-mediated phosphorylation and activation. Biochem J 2006 1.27
31 Knockout of the intermediate filament protein CP49 destabilises the lens fibre cell cytoskeleton and decreases lens optical quality, but does not induce cataract. Exp Eye Res 2003 1.26
32 Trypanosoma brucei glycoproteins contain novel giant poly-N-acetyllactosamine carbohydrate chains. J Biol Chem 2004 1.24
33 Desmin aggregate formation by R120G alphaB-crystallin is caused by altered filament interactions and is dependent upon network status in cells. Mol Biol Cell 2004 1.23
34 ERK/p90(RSK)/14-3-3 signalling has an impact on expression of PEA3 Ets transcription factors via the transcriptional repressor capicúa. Biochem J 2011 1.17
35 Burkholderia phymatum is a highly effective nitrogen-fixing symbiont of Mimosa spp. and fixes nitrogen ex planta. New Phytol 2007 1.17
36 Fin development in a cartilaginous fish and the origin of vertebrate limbs. Nature 2002 1.16
37 The Alexander disease-causing glial fibrillary acidic protein mutant, R416W, accumulates into Rosenthal fibers by a pathway that involves filament aggregation and the association of alpha B-crystallin and HSP27. Am J Hum Genet 2006 1.13
38 Bfsp2 mutation found in mouse 129 strains causes the loss of CP49' and induces vimentin-dependent changes in the lens fibre cell cytoskeleton. Exp Eye Res 2004 1.11
39 Proximal effects of Toll-like receptor activation in dendritic cells. Curr Opin Immunol 2006 1.11
40 p14 Arf promotes small ubiquitin-like modifier conjugation of Werners helicase. J Biol Chem 2004 1.07
41 FGF-2 release from the lens capsule by MMP-2 maintains lens epithelial cell viability. Mol Biol Cell 2007 1.07
42 Regulation of the polarity kinases PAR-1/MARK by 14-3-3 interaction and phosphorylation. J Cell Sci 2006 1.05
43 The synthesis of UDP-N-acetylglucosamine is essential for bloodstream form trypanosoma brucei in vitro and in vivo and UDP-N-acetylglucosamine starvation reveals a hierarchy in parasite protein glycosylation. J Biol Chem 2008 1.02
44 TLR ligand-induced podosome disassembly in dendritic cells is ADAM17 dependent. J Cell Biol 2008 1.02
45 Activated cAMP receptors switch encystation into sporulation. Proc Natl Acad Sci U S A 2009 1.00
46 Ninein is released from the centrosome and moves bi-directionally along microtubules. J Cell Sci 2007 0.97
47 Cellular responses to the metal-binding properties of metformin. Diabetes 2012 0.96
48 Inositol phospholipids regulate the guanine-nucleotide-exchange factor Tiam1 by facilitating its binding to the plasma membrane and regulating GDP/GTP exchange on Rac1. Biochem J 2004 0.95
49 A role for ARF6 in dendritic cell podosome formation and migration. Eur J Immunol 2008 0.94
50 Homeostasis in the vertebrate lens: mechanisms of solute exchange. Philos Trans R Soc Lond B Biol Sci 2011 0.93
51 Depletion of protein phosphatase 4 in human cells reveals essential roles in centrosome maturation, cell migration and the regulation of Rho GTPases. Int J Biochem Cell Biol 2008 0.92
52 Observation of keratin particles showing fast bidirectional movement colocalized with microtubules. J Cell Sci 2003 0.91
53 Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1. Biochem J 2003 0.89
54 Sigma receptor antagonists inhibit human lens cell growth and induce pigmentation. Invest Ophthalmol Vis Sci 2005 0.86
55 Association of the nuclear matrix component NuMA with the Cajal body and nuclear speckle compartments during transitions in transcriptional activity in lens cell differentiation. Eur J Cell Biol 2002 0.85
56 Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6. Sci Rep 2013 0.85
57 A role for PP1/NIPP1 in steering migration of human cancer cells. PLoS One 2012 0.84
58 Deletion of the GPIdeAc gene alters the location and fate of glycosylphosphatidylinositol precursors in Trypanosoma brucei. Biochemistry 2003 0.84
59 A synthetic system for expression of components of a bacterial microcompartment. Microbiology 2013 0.84
60 Expression and localisation of apical junctional complex proteins in lens epithelial cells. Exp Eye Res 2008 0.84
61 Bfsp2 mutation found in mouse 129 strains causes the loss of CP49 and induces vimentin-dependent changes in the lens fibre cell cytoskeleton. Exp Eye Res 2004 0.83
62 The specificity of the interaction between αB-crystallin and desmin filaments and its impact on filament aggregation and cell viability. Philos Trans R Soc Lond B Biol Sci 2013 0.82
63 Fate of glycosylphosphatidylinositol (GPI)-less procyclin and characterization of sialylated non-GPI-anchored surface coat molecules of procyclic-form Trypanosoma brucei. Eukaryot Cell 2009 0.81
64 Increased SK3 expression in DM1 lens cells leads to impaired growth through a greater calcium-induced fragility. Hum Mol Genet 2006 0.81
65 Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases. Biochem J 2014 0.81
66 The intermediate filament systems in the eye lens. Methods Cell Biol 2004 0.81
67 The anti-neurodegenerative agent clioquinol regulates the transcription factor FOXO1a. Biochem J 2012 0.79
68 Protein phosphatase 4 is phosphorylated and inactivated by Cdk in response to spindle toxins and interacts with γ-tubulin. Cell Cycle 2013 0.79
69 ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase. J Cell Sci 2012 0.79
70 Evolution of the vertebrate beaded filament protein, Bfsp2; comparing the in vitro assembly properties of a "tailed" zebrafish Bfsp2 to its "tailless" human orthologue. Exp Eye Res 2011 0.79
71 Endocytosis of DNA-Hsp65 alters the pH of the late endosome/lysosome and interferes with antigen presentation. PLoS One 2007 0.78
72 Morphological changes and nuclear pore clustering during nuclear degradation in differentiating bovine lens fibre cells. Ophthalmic Res 2002 0.77
73 Reorganization of centrosomal marker proteins coincides with epithelial cell differentiation in the vertebrate lens. Exp Eye Res 2007 0.76