PubRank

Mario J A Saad

Author PubWeight™ 67.44‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Retracted Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance. Diabetes 2007 5.67
2 IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition. PLoS Biol 2010 2.21
3 High- or low-salt diet from weaning to adulthood: effect on body weight, food intake and energy balance in rats. Nutr Metab Cardiovasc Dis 2005 2.15
4 S-nitrosation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt: a novel mechanism of insulin resistance. Diabetes 2005 1.91
5 Metformin amplifies chemotherapy-induced AMPK activation and antitumoral growth. Clin Cancer Res 2011 1.88
6 Retracted A central role for neuronal AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) in high-protein diet-induced weight loss. Diabetes 2007 1.59
7 Retracted Exercise improves insulin and leptin sensitivity in hypothalamus of Wistar rats. Diabetes 2006 1.57
8 Reversal of diet-induced insulin resistance with a single bout of exercise in the rat: the role of PTP1B and IRS-1 serine phosphorylation. J Physiol 2006 1.56
9 Retracted Physical exercise reduces circulating lipopolysaccharide and TLR4 activation and improves insulin signaling in tissues of DIO rats. Diabetes 2011 1.50
10 Cross-talk between the insulin and leptin signaling systems in rat hypothalamus. Obes Res 2005 1.48
11 Acute physical exercise reverses S-nitrosation of the insulin receptor, insulin receptor substrate 1 and protein kinase B/Akt in diet-induced obese Wistar rats. J Physiol 2007 1.38
12 Novel signal transduction pathway for luteinizing hormone and its interaction with insulin: activation of Janus kinase/signal transducer and activator of transcription and phosphoinositol 3-kinase/Akt pathways. Endocrinology 2003 1.18
13 The multi-faceted cross-talk between the insulin and angiotensin II signaling systems. Diabetes Metab Res Rev 2006 1.16
14 Obesity-induced increase in tumor necrosis factor-α leads to development of colon cancer in mice. Gastroenterology 2012 1.14
15 Targeted disruption of iNOS prevents LPS-induced S-nitrosation of IRbeta/IRS-1 and Akt and insulin resistance in muscle of mice. Am J Physiol Endocrinol Metab 2006 1.13
16 Endurance training improves responsiveness to insulin and modulates insulin signal transduction through the phosphatidylinositol 3-kinase/Akt-1 pathway. Eur J Endocrinol 2002 1.10
17 Retracted EGFR tyrosine kinase inhibitor (PD153035) improves glucose tolerance and insulin action in high-fat diet-fed mice. Diabetes 2009 1.08
18 Hepatocyte growth factor plays a key role in insulin resistance-associated compensatory mechanisms. Endocrinology 2012 1.06
19 Central exercise action increases the AMPK and mTOR response to leptin. PLoS One 2008 1.05
20 Interaction between leptin and insulin signaling pathways differentially affects JAK-STAT and PI 3-kinase-mediated signaling in rat liver. Biol Chem 2003 1.03
21 Antineoplastic effect of rapamycin is potentiated by inhibition of IRS-1 signaling in prostate cancer cells xenografts. J Cancer Res Clin Oncol 2008 1.03
22 Modulation of double-stranded RNA-activated protein kinase in insulin sensitive tissues of obese humans. Obesity (Silver Spring) 2013 1.01
23 Double-stranded RNA-activated protein kinase is a key modulator of insulin sensitivity in physiological conditions and in obesity in mice. Endocrinology 2012 1.01
24 Topical insulin accelerates wound healing in diabetes by enhancing the AKT and ERK pathways: a double-blind placebo-controlled clinical trial. PLoS One 2012 1.01
25 The role of gut microbiota on insulin resistance. Nutrients 2013 0.99
26 Diacerhein improves glucose tolerance and insulin sensitivity in mice on a high-fat diet. Endocrinology 2011 0.98
27 Cold-induced PGC-1alpha expression modulates muscle glucose uptake through an insulin receptor/Akt-independent, AMPK-dependent pathway. Am J Physiol Endocrinol Metab 2004 0.96
28 Targeted disruption of inducible nitric oxide synthase protects against aging, S-nitrosation, and insulin resistance in muscle of male mice. Diabetes 2012 0.96
29 Regulation of Cbl-associated protein/Cbl pathway in muscle and adipose tissues of two animal models of insulin resistance. Endocrinology 2003 0.94
30 A central role for neuronal adenosine 5'-monophosphate-activated protein kinase in cancer-induced anorexia. Endocrinology 2007 0.94
31 The cross-talk between angiotensin and insulin differentially affects phosphatidylinositol 3-kinase- and mitogen-activated protein kinase-mediated signaling in rat heart: implications for insulin resistance. Endocrinology 2003 0.91
32 Tumor necrosis factor-alpha activates signal transduction in hypothalamus and modulates the expression of pro-inflammatory proteins and orexigenic/anorexigenic neurotransmitters. J Neurochem 2006 0.90
33 Retracted Tub has a key role in insulin and leptin signaling and action in vivo in hypothalamic nuclei. Diabetes 2012 0.89
34 Exercise intensity, inflammatory signaling, and insulin resistance in obese rats. Med Sci Sports Exerc 2010 0.88
35 Up-regulation of the phosphatidylinositol 3-kinase/protein kinase B pathway in the ovary of rats by chronic treatment with hCG and insulin. J Endocrinol 2006 0.88
36 Defective insulin and acetylcholine induction of endothelial cell-nitric oxide synthase through insulin receptor substrate/Akt signaling pathway in aorta of obese rats. Diabetes 2007 0.86
37 Acute exercise induces a phenotypic switch in adipose tissue macrophage polarization in diet-induced obese rats. Obesity (Silver Spring) 2013 0.86
38 Topiramate treatment improves hypothalamic insulin and leptin signaling and action and reduces obesity in mice. Endocrinology 2012 0.86
39 Gut microbiota composition and its effects on obesity and insulin resistance. Curr Opin Clin Nutr Metab Care 2014 0.86
40 Reversal of denervation-induced insulin resistance by SHIP2 protein synthesis blockade. Am J Physiol Endocrinol Metab 2002 0.85
41 Acute exercise reverses aged-induced impairments in insulin signaling in rodent skeletal muscle. Mech Ageing Dev 2010 0.85
42 Phosphoinositide-specific inositol polyphosphate 5-phosphatase IV inhibits inositide trisphosphate accumulation in hypothalamus and regulates food intake and body weight. Endocrinology 2006 0.85
43 Insulin-resistance-associated compensatory mechanisms of pancreatic Beta cells: a current opinion. Front Endocrinol (Lausanne) 2013 0.84
44 Regulation of insulin receptor substrate-2 tyrosine phosphorylation in animal models of insulin resistance. Endocrine 2003 0.83
45 Modulation of growth hormone signal transduction in kidneys of streptozotocin-induced diabetic animals: effect of a growth hormone receptor antagonist. Diabetes 2002 0.83
46 BCR-ABL binds to IRS-1 and IRS-1 phosphorylation is inhibited by imatinib in K562 cells. FEBS Lett 2003 0.82
47 A new overtraining protocol for mice based on downhill running sessions. Clin Exp Pharmacol Physiol 2012 0.82
48 Aspirin inhibits serine phosphorylation of IRS-1 in muscle and adipose tissue of septic rats. Biochem Biophys Res Commun 2004 0.81
49 Diet-induced obesity induces endoplasmic reticulum stress and insulin resistance in the amygdala of rats. FEBS Open Bio 2013 0.81
50 Kinin B1 receptor in adipocytes regulates glucose tolerance and predisposition to obesity. PLoS One 2012 0.79
51 Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in growth hormone treated animals. FEBS Lett 2005 0.79
52 Blockade of IRS1 in isolated rat pancreatic islets improves glucose-induced insulin secretion. FEBS Lett 2002 0.78
53 [Metabolic syndrome: still undefined, but usefull to identify high risk for cardiovascular disease]. Arq Bras Endocrinol Metabol 2006 0.78
54 The Gly972Arg polymorphism in insulin receptor substrate-1 is associated with decreased birth weight in a population-based sample of Brazilian newborns. Diabetes Care 2002 0.78
55 Birth weight and type 2 diabetes in adults. JAMA 2009 0.77
56 Lack of Arg972 polymorphism in the IRS1 gene in Parakanã Brazilian Indians. Hum Biol 2004 0.77
57 Delta cell death in the islet of Langerhans and the progression from normal glucose tolerance to type 2 diabetes in non-human primates (baboon, Papio hamadryas). Diabetologia 2015 0.77
58 [Insulin resistance/hyperinsulinemia associated diseases not included in the metabolic syndrome]. Arq Bras Endocrinol Metabol 2006 0.76
59 G120K-PEG, a human GH antagonist, decreases GH signal transduction in the liver of mice. Mol Cell Endocrinol 2002 0.76
60 Effects of NH4Cl intake on renal growth in rats: role of MAPK signalling pathway. Nephrol Dial Transplant 2005 0.76
61 Comment on: Ramos-Zavala et al. Effect of diacerein on insulin secretion and metabolic control in drug-naïve patients with type 2 diabetes: a randomized clinical trial. Diabetes Care 2011;34:1591-1594. Diabetes Care 2012 0.75
62 Statement of Retraction. A Central Role for Neuronal AMP-Activated Protein Kinase (AMPK) and Mammalian Target of Rapamycin (mTOR) in High-Protein Diet-Induced Weight Loss. Diabetes 2008;57:594-605. DOI: 10.2337/db07-0573. Diabetes 2017 0.75
63 Statement of Retraction. Physical Exercise Reduces Circulating Lipopolysaccharide and TLR4 Activation and Improves Insulin Signaling in Tissues of DIO Rats. Diabetes 2011;60:784-796. DOI: 10.2337/db09-1907. Diabetes 2016 0.75
64 Expression of Concern. Tub Has a Key Role in Insulin and Leptin Signaling and Action In Vivo in Hypothalamic Nuclei. Diabetes 2013;62:137-148. DOI: 10.2337/db11-1388. Diabetes 2016 0.75
65 Expression of Concern. A Central Role for Neuronal AMP-Activated Protein Kinase (AMPK) and Mammalian Target of Rapamycin (mTOR) in High-Protein Diet-Induced Weight Loss. Diabetes 2008;57:594-605. DOI: 10.2337/db07-0573. Diabetes 2016 0.75
66 Statement of Retraction. Effect of Captopril, Losartan, and Bradykinin on Early Steps of Insulin Action. Diabetes 1997;46:1950-1957. DOI: 10.2337/diab.46.12.1950. Diabetes 2016 0.75
67 Statement of Retraction. Loss-of-Function Mutation in Toll-Like Receptor 4 Prevents Diet-Induced Obesity and Insulin Resistance. Diabetes 2007;56:1986-1998. DOI: 10.2337/db06-1595. Diabetes 2016 0.75
68 Statement of Retraction. Exercise Improves Insulin and Leptin Sensitivity in Hypothalamus of Wistar Rats. Diabetes 2006;55:2554-2561. DOI: 10.2337/db05-1622. Diabetes 2016 0.75
69 Statement of Retraction. EGFR Tyrosine Kinase Inhibitor (PD153035) Improves Glucose Tolerance and Insulin Action in High-Fat Diet-Fed Mice. Diabetes 2009;58:2910-2919. DOI: 10.2337/db08-0506. PMID: 19696185. Diabetes 2017 0.75
70 Statement of Retraction. Tub Has a Key Role in Insulin and Leptin Signaling and Action In Vivo in Hypothalamic Nuclei. Diabetes 2013;62:137-148. DOI: 10.2337/db11-1388. Diabetes 2017 0.75
71 Evidence for a direct effect of captopril on early steps of insulin action in BC3H-1 myocytes. Metabolism 2003 0.75
72 Expression of Concern. EGFR Tyrosine Kinase Inhibitor (PD153035) Improves Glucose Tolerance and Insulin Action in High-Fat Diet-Fed Mice. Diabetes 2009;58:2910-2919. DOI: 10.2337/db08-0506. PMID: 19696185. Diabetes 2017 0.75