Published in J Biol Inorg Chem on September 06, 2002
Ferritins, iron uptake and storage from the bacterioferritin viewpoint. EMBO J (2003) 1.94
Biological inorganic chemistry at the beginning of the 21st century. Proc Natl Acad Sci U S A (2003) 1.43
Moving metal ions through ferritin-protein nanocages from three-fold pores to catalytic sites. J Am Chem Soc (2010) 1.23
Ferritin reactions: direct identification of the site for the diferric peroxide reaction intermediate. Proc Natl Acad Sci U S A (2004) 1.12
Ferritin structure from Mycobacterium tuberculosis: comparative study with homologues identifies extended C-terminus involved in ferroxidase activity. PLoS One (2011) 1.03
Crystal structure of plant ferritin reveals a novel metal binding site that functions as a transit site for metal transfer in ferritin. J Biol Chem (2009) 0.97
Self-assembling protein nanoparticles in the design of vaccines. Comput Struct Biotechnol J (2015) 0.87
Iron chaperones for mitochondrial Fe-S cluster biosynthesis and ferritin iron storage. Curr Opin Chem Biol (2011) 0.78
Fe(2+) substrate transport through ferritin protein cage ion channels influences enzyme activity and biomineralization. J Biol Inorg Chem (2015) 0.78
Chemistry at the protein-mineral interface in L-ferritin assists the assembly of a functional (μ(3)-oxo)Tris[(μ(2)-peroxo)] triiron(III) cluster. Proc Natl Acad Sci U S A (2017) 0.75
Cloning, purification and preliminary X-ray crystallographic analysis of a hypothetical protein, MJ0754, from Methanococcus jannaschii DSM 2661. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.75
Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury. J Clin Invest (2013) 1.73
Alterations of systemic and muscle iron metabolism in human subjects treated with low-dose recombinant erythropoietin. Blood (2009) 1.66
Differential regulation of iron homeostasis during human macrophage polarized activation. Eur J Immunol (2010) 1.64
The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging. Proc Natl Acad Sci U S A (2004) 1.59
Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia. Blood (2002) 1.49
RNA silencing of the mitochondrial ABCB7 transporter in HeLa cells causes an iron-deficient phenotype with mitochondrial iron overload. Blood (2006) 1.38
Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis. Blood (2007) 1.36
Genetic hyperferritinaemia and reticuloendothelial iron overload associated with a three base pair deletion in the coding region of the ferroportin gene (SLC11A3). Br J Haematol (2002) 1.32
Mitochondrial ferritin limits oxidative damage regulating mitochondrial iron availability: hypothesis for a protective role in Friedreich ataxia. Hum Mol Genet (2008) 1.30
Mitochondrial ferritin: a new player in iron metabolism. Blood Cells Mol Dis (2003) 1.29
Annexin-A5 assembled into two-dimensional arrays promotes cell membrane repair. Nat Commun (2011) 1.28
The dentate nucleus in Friedreich's ataxia: the role of iron-responsive proteins. Acta Neuropathol (2007) 1.27
Multiple pathways for mineral core formation in mammalian apoferritin. The role of hydrogen peroxide. Biochemistry (2003) 1.26
The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation. J Am Chem Soc (2014) 1.22
Human mitochondrial ferritin expressed in HeLa cells incorporates iron and affects cellular iron metabolism. J Biol Chem (2002) 1.22
Mitochondrial ferritin. Int J Biochem Cell Biol (2004) 1.21
New functions for an iron storage protein: the role of ferritin in immunity and autoimmunity. J Autoimmun (2008) 1.21
Heparin: a potent inhibitor of hepcidin expression in vitro and in vivo. Blood (2010) 1.20
Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin. Blood (2003) 1.20
Unique iron binding and oxidation properties of human mitochondrial ferritin: a comparative analysis with Human H-chain ferritin. J Mol Biol (2005) 1.20
Protein crystallography under xenon and nitrous oxide pressure: comparison with in vivo pharmacology studies and implications for the mechanism of inhaled anesthetic action. Biophys J (2006) 1.19
The expression of human mitochondrial ferritin rescues respiratory function in frataxin-deficient yeast. Hum Mol Genet (2004) 1.19
Mitochondrial ferritin expression in adult mouse tissues. J Histochem Cytochem (2007) 1.17
Ferritin functions as a proinflammatory cytokine via iron-independent protein kinase C zeta/nuclear factor kappaB-regulated signaling in rat hepatic stellate cells. Hepatology (2009) 1.15
Identification of new mutations of the HFE, hepcidin, and transferrin receptor 2 genes by denaturing HPLC analysis of individuals with biochemical indications of iron overload. Clin Chem (2003) 1.15
Crystal structure and biochemical properties of the human mitochondrial ferritin and its mutant Ser144Ala. J Mol Biol (2004) 1.15
Ferrous ion binding to recombinant human H-chain ferritin. An isothermal titration calorimetry study. Biochemistry (2002) 1.12
mu-1,2-Peroxobridged di-iron(III) dimer formation in human H-chain ferritin. Biochem J (2002) 1.11
Neuroferritinopathy: a neurodegenerative disorder associated with L-ferritin mutation. Best Pract Res Clin Haematol (2005) 1.11
Water-dispersible sugar-coated iron oxide nanoparticles. An evaluation of their relaxometric and magnetic hyperthermia properties. J Am Chem Soc (2011) 1.09
Crystal structure of grape dihydroflavonol 4-reductase, a key enzyme in flavonoid biosynthesis. J Mol Biol (2007) 1.08
Biofortification for combating 'hidden hunger' for iron. Trends Plant Sci (2011) 1.07
Design of water-based ferrofluids as contrast agents for magnetic resonance imaging. J Colloid Interface Sci (2011) 1.06
Relative contribution of iron genes, dysmetabolism and hepatitis C virus (HCV) in the pathogenesis of altered iron regulation in HCV chronic hepatitis. Haematologica (2007) 1.06
Leucine-zipper-mediated homo- and hetero-dimerization of GIT family p95-ARF GTPase-activating protein, PIX-, paxillin-interacting proteins 1 and 2. Biochem J (2003) 1.04
Ferritin ferroxidase activity: a potent inhibitor of osteogenesis. J Bone Miner Res (2010) 1.03
Glycol-split nonanticoagulant heparins are inhibitors of hepcidin expression in vitro and in vivo. Blood (2014) 1.03
Ferritin as an important player in neurodegeneration. Parkinsonism Relat Disord (2011) 1.03
Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis. J Neurosci (2009) 1.03
Chemical-physical changes in cell membrane microdomains of breast cancer cells after omega-3 PUFA incorporation. Cell Biochem Biophys (2012) 0.99
The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin. Biochim Biophys Acta (2007) 0.99
Origin of the unusual kinetics of iron deposition in human H-chain ferritin. J Am Chem Soc (2005) 0.99
Heavy chain ferritin activates regulatory T cells by induction of changes in dendritic cells. Blood (2002) 0.99
Association of increased levels of heavy-chain ferritin with increased CD4+ CD25+ regulatory T-cell levels in patients with melanoma. Clin Cancer Res (2003) 0.99
Doxorubicin paradoxically protects cardiomyocytes against iron-mediated toxicity: role of reactive oxygen species and ferritin. J Biol Chem (2004) 0.98
Microelectronic DNA chip for hereditary hyperferritinemia cataract syndrome, a model for large-scale analysis of disorders of iron metabolism. Hum Mutat (2006) 0.97
Mitochondrial ferritin in the substantia nigra in restless legs syndrome. J Neuropathol Exp Neurol (2009) 0.97
Transferrin receptor 2 and HFE regulate furin expression via mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/Erk) signaling. Implications for transferrin-dependent hepcidin regulation. Haematologica (2010) 0.96
Identification of new mutations of hepcidin and hemojuvelin in patients with HFE C282Y allele. Blood Cells Mol Dis (2004) 0.96
Oxidative stress and cell death in cells expressing L-ferritin variants causing neuroferritinopathy. Neurobiol Dis (2009) 0.94
Scanning mutations of the 5'UTR regulatory sequence of L-ferritin by denaturing high-performance liquid chromatography: identification of new mutations. Br J Haematol (2003) 0.94
Strong iron demand during hypoxia-induced erythropoiesis is associated with down-regulation of iron-related proteins and myoglobin in human skeletal muscle. Blood (2007) 0.93
Myelination and motor coordination are increased in transferrin transgenic mice. J Neurosci Res (2003) 0.92
Pantothenate kinase-2 (Pank2) silencing causes cell growth reduction, cell-specific ferroportin upregulation and iron deregulation. Neurobiol Dis (2010) 0.92
Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation. J Biol Chem (2010) 0.92
ELISA reveals a difference in the structure of substantia nigra ferritin in Parkinson's disease and incidental Lewy body compared to control. Parkinsonism Relat Disord (2007) 0.91
Ferritin prevents calcification and osteoblastic differentiation of vascular smooth muscle cells. J Am Soc Nephrol (2009) 0.90
Fusion of the antiferritin antibody VL domain to barnase results in enhanced solubility and altered pH stability. Protein Eng Des Sel (2004) 0.90
The putative "nucleation site" in human H-chain ferritin is not required for mineralization of the iron core. Biochemistry (2004) 0.89
Facilitated diffusion of iron(II) and dioxygen substrates into human H-chain ferritin. A fluorescence and absorbance study employing the ferroxidase center substitution Y34W. J Am Chem Soc (2008) 0.89
Analysis of ferritin genes in Parkinson disease. Clin Chem Lab Med (2007) 0.89
Relation of cytosolic iron excess to cardiomyopathy of Friedreich's ataxia. Am J Cardiol (2012) 0.89
Role of iron and ferritin in TNFalpha-induced apoptosis in HeLa cells. FEBS Lett (2003) 0.88
Iron(II) and hydrogen peroxide detoxification by human H-chain ferritin. An EPR spin-trapping study. Biochemistry (2006) 0.87
Liver iron modulates hepcidin expression during chronically elevated erythropoiesis in mice. Hepatology (2013) 0.87
Structure and epimerase activity of anthocyanidin reductase from Vitis vinifera. Acta Crystallogr D Biol Crystallogr (2009) 0.87
New TFR2 mutations in young Italian patients with hemochromatosis. Haematologica (2008) 0.87
Iron increases the susceptibility of multiple myeloma cells to bortezomib. Haematologica (2012) 0.87
The sedimentation properties of ferritins. New insights and analysis of methods of nanoparticle preparation. Biochim Biophys Acta (2010) 0.87
Annexin-A6 presents two modes of association with phospholipid membranes. A combined QCM-D, AFM and cryo-TEM study. J Struct Biol (2009) 0.87
Identification of two novel mutations in the 5'-untranslated region of H-ferritin using denaturing high performance liquid chromatography scanning. Haematologica (2003) 0.86
Skin fibroblasts from pantothenate kinase-associated neurodegeneration patients show altered cellular oxidative status and have defective iron-handling properties. Hum Mol Genet (2012) 0.86
Correlation between the bone density recorded by a computerized implant motor and by a histomorphometric analysis: a preliminary in vitro study on bovine ribs. Clin Implant Dent Relat Res (2013) 0.86
Human L-ferritin deficiency is characterized by idiopathic generalized seizures and atypical restless leg syndrome. J Exp Med (2013) 0.86
Characterization of the l-ferritin variant 460InsA responsible of a hereditary ferritinopathy disorder. Neurobiol Dis (2006) 0.86
Defining metal ion inhibitor interactions with recombinant human H- and L-chain ferritins and site-directed variants: an isothermal titration calorimetry study. J Biol Inorg Chem (2003) 0.85
Comparative study between Hfe-/- and beta2m-/- mice: progression with age of iron status and liver pathology. Int J Exp Pathol (2006) 0.85
Ferritin--a mediator of apoptosis? J Cell Physiol (2007) 0.85
A single amino acid change within the R2 domain of the VvMYB5b transcription factor modulates affinity for protein partners and target promoters selectivity. BMC Plant Biol (2011) 0.84
Structure of a complex formed by a protein and a helical aromatic oligoamide foldamer at 2.1 Å resolution. Angew Chem Int Ed Engl (2013) 0.84
Mice lacking mitochondrial ferritin are more sensitive to doxorubicin-mediated cardiotoxicity. J Mol Med (Berl) (2014) 0.84
HFE gene mutations in a population of Italian Parkinson's disease patients. Parkinsonism Relat Disord (2008) 0.84