Published in Int J Biochem Cell Biol on October 01, 2004
Regulation of cellular iron metabolism. Biochem J (2011) 3.03
Serum ferritin: Past, present and future. Biochim Biophys Acta (2010) 1.80
The structure and function of frataxin. Crit Rev Biochem Mol Biol (2006) 1.59
Heme degradation and vascular injury. Antioxid Redox Signal (2010) 1.48
Characterization of mitochondrial ferritin in Drosophila. Proc Natl Acad Sci U S A (2006) 1.41
The long history of iron in the Universe and in health and disease. Biochim Biophys Acta (2011) 1.33
Mitochondrial ferritin limits oxidative damage regulating mitochondrial iron availability: hypothesis for a protective role in Friedreich ataxia. Hum Mol Genet (2008) 1.30
Acidic residues of yeast frataxin have an essential role in Fe-S cluster assembly. EMBO Rep (2006) 1.24
The MCK mouse heart model of Friedreich's ataxia: Alterations in iron-regulated proteins and cardiac hypertrophy are limited by iron chelation. Proc Natl Acad Sci U S A (2008) 1.22
Mitochondrial ferritin expression in adult mouse tissues. J Histochem Cytochem (2007) 1.17
The emerging role of iron dyshomeostasis in the mitochondrial decay of aging. Mech Ageing Dev (2010) 1.00
Copper and iron homeostasis in plants: the challenges of oxidative stress. Antioxid Redox Signal (2013) 0.99
Mitochondrial ferritin in the substantia nigra in restless legs syndrome. J Neuropathol Exp Neurol (2009) 0.97
A possible role for secreted ferritin in tissue iron distribution. J Neural Transm (Vienna) (2011) 0.96
The IRP/IRE system in vivo: insights from mouse models. Front Pharmacol (2014) 0.96
Characterization of nuclear ferritin and mechanism of translocation. Biochem J (2005) 0.95
Mapping brain metals to evaluate therapies for neurodegenerative disease. CNS Neurosci Ther (2010) 0.91
Insect ferritins: Typical or atypical? Biochim Biophys Acta (2010) 0.91
Multi-copper oxidases and human iron metabolism. Nutrients (2013) 0.90
Genome-wide identification of molecular pathways and biomarkers in response to arsenic exposure in zebrafish liver. PLoS One (2013) 0.89
Manipulation of in vivo iron levels can alter resistance to oxidative stress without affecting ageing in the nematode C. elegans. Mech Ageing Dev (2012) 0.87
Human L-ferritin deficiency is characterized by idiopathic generalized seizures and atypical restless leg syndrome. J Exp Med (2013) 0.86
Over-expression of mitochondrial ferritin affects the JAK2/STAT5 pathway in K562 cells and causes mitochondrial iron accumulation. Haematologica (2011) 0.84
Mice lacking mitochondrial ferritin are more sensitive to doxorubicin-mediated cardiotoxicity. J Mol Med (Berl) (2014) 0.84
Expression and localization of mitochondrial ferritin mRNA in Alzheimer's disease cerebral cortex. PLoS One (2011) 0.84
Characterization of mitochondrial ferritin-deficient mice. Am J Hematol (2010) 0.83
Macrophage and epithelial cell H-ferritin expression regulates renal inflammation. Kidney Int (2015) 0.82
Oxidative stress and the homeodynamics of iron metabolism. Biomolecules (2015) 0.79
Genome-wide comparison of ferritin family from Archaea, Bacteria, Eukarya, and Viruses: its distribution, characteristic motif, and phylogenetic relationship. Naturwissenschaften (2015) 0.76
Characterization of a Novel Monoclonal Antibody against Human Mitochondrial Ferritin and Its Immunohistochemical Application in Human and Monkey Substantia Nigra. Acta Histochem Cytochem (2017) 0.75
Characterization of human mitochondrial ferritin promoter: identification of transcription factors and evidences of epigenetic control. Sci Rep (2016) 0.75
Lack of mitochondrial ferritin aggravates neurological deficits via enhancing oxidative stress in a traumatic brain injury murine model. Biosci Rep (2017) 0.75
Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury. J Clin Invest (2013) 1.73
The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging. Proc Natl Acad Sci U S A (2004) 1.59
Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia. Blood (2002) 1.49
RNA silencing of the mitochondrial ABCB7 transporter in HeLa cells causes an iron-deficient phenotype with mitochondrial iron overload. Blood (2006) 1.38
Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis. Blood (2007) 1.36
Genetic hyperferritinaemia and reticuloendothelial iron overload associated with a three base pair deletion in the coding region of the ferroportin gene (SLC11A3). Br J Haematol (2002) 1.32
Mitochondrial ferritin: a new player in iron metabolism. Blood Cells Mol Dis (2003) 1.29
Multiple pathways for mineral core formation in mammalian apoferritin. The role of hydrogen peroxide. Biochemistry (2003) 1.26
The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation. J Am Chem Soc (2014) 1.22
Human mitochondrial ferritin expressed in HeLa cells incorporates iron and affects cellular iron metabolism. J Biol Chem (2002) 1.22
New functions for an iron storage protein: the role of ferritin in immunity and autoimmunity. J Autoimmun (2008) 1.21
Heparin: a potent inhibitor of hepcidin expression in vitro and in vivo. Blood (2010) 1.20
Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin. Blood (2003) 1.20
Unique iron binding and oxidation properties of human mitochondrial ferritin: a comparative analysis with Human H-chain ferritin. J Mol Biol (2005) 1.20
The expression of human mitochondrial ferritin rescues respiratory function in frataxin-deficient yeast. Hum Mol Genet (2004) 1.19
Mitochondrial ferritin expression in adult mouse tissues. J Histochem Cytochem (2007) 1.17
Ferritin functions as a proinflammatory cytokine via iron-independent protein kinase C zeta/nuclear factor kappaB-regulated signaling in rat hepatic stellate cells. Hepatology (2009) 1.15
Identification of new mutations of the HFE, hepcidin, and transferrin receptor 2 genes by denaturing HPLC analysis of individuals with biochemical indications of iron overload. Clin Chem (2003) 1.15
Crystal structure and biochemical properties of the human mitochondrial ferritin and its mutant Ser144Ala. J Mol Biol (2004) 1.15
Ferrous ion binding to recombinant human H-chain ferritin. An isothermal titration calorimetry study. Biochemistry (2002) 1.12
mu-1,2-Peroxobridged di-iron(III) dimer formation in human H-chain ferritin. Biochem J (2002) 1.11
Neuroferritinopathy: a neurodegenerative disorder associated with L-ferritin mutation. Best Pract Res Clin Haematol (2005) 1.11
Water-dispersible sugar-coated iron oxide nanoparticles. An evaluation of their relaxometric and magnetic hyperthermia properties. J Am Chem Soc (2011) 1.09
Biofortification for combating 'hidden hunger' for iron. Trends Plant Sci (2011) 1.07
Relative contribution of iron genes, dysmetabolism and hepatitis C virus (HCV) in the pathogenesis of altered iron regulation in HCV chronic hepatitis. Haematologica (2007) 1.06
Design of water-based ferrofluids as contrast agents for magnetic resonance imaging. J Colloid Interface Sci (2011) 1.06
Ferritin ferroxidase activity: a potent inhibitor of osteogenesis. J Bone Miner Res (2010) 1.03
Glycol-split nonanticoagulant heparins are inhibitors of hepcidin expression in vitro and in vivo. Blood (2014) 1.03
Ferritin as an important player in neurodegeneration. Parkinsonism Relat Disord (2011) 1.03
Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis. J Neurosci (2009) 1.03
The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin. Biochim Biophys Acta (2007) 0.99
Origin of the unusual kinetics of iron deposition in human H-chain ferritin. J Am Chem Soc (2005) 0.99
Chemical-physical changes in cell membrane microdomains of breast cancer cells after omega-3 PUFA incorporation. Cell Biochem Biophys (2012) 0.99
Heavy chain ferritin activates regulatory T cells by induction of changes in dendritic cells. Blood (2002) 0.99
Association of increased levels of heavy-chain ferritin with increased CD4+ CD25+ regulatory T-cell levels in patients with melanoma. Clin Cancer Res (2003) 0.99
Structural description of the active sites of mouse L-chain ferritin at 1.2 A resolution. J Biol Inorg Chem (2002) 0.97
Microelectronic DNA chip for hereditary hyperferritinemia cataract syndrome, a model for large-scale analysis of disorders of iron metabolism. Hum Mutat (2006) 0.97
Mitochondrial ferritin in the substantia nigra in restless legs syndrome. J Neuropathol Exp Neurol (2009) 0.97
Identification of new mutations of hepcidin and hemojuvelin in patients with HFE C282Y allele. Blood Cells Mol Dis (2004) 0.96
Transferrin receptor 2 and HFE regulate furin expression via mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/Erk) signaling. Implications for transferrin-dependent hepcidin regulation. Haematologica (2010) 0.96
Oxidative stress and cell death in cells expressing L-ferritin variants causing neuroferritinopathy. Neurobiol Dis (2009) 0.94
Scanning mutations of the 5'UTR regulatory sequence of L-ferritin by denaturing high-performance liquid chromatography: identification of new mutations. Br J Haematol (2003) 0.94
Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation. J Biol Chem (2010) 0.92
Pantothenate kinase-2 (Pank2) silencing causes cell growth reduction, cell-specific ferroportin upregulation and iron deregulation. Neurobiol Dis (2010) 0.92
ELISA reveals a difference in the structure of substantia nigra ferritin in Parkinson's disease and incidental Lewy body compared to control. Parkinsonism Relat Disord (2007) 0.91
Ferritin prevents calcification and osteoblastic differentiation of vascular smooth muscle cells. J Am Soc Nephrol (2009) 0.90
Fusion of the antiferritin antibody VL domain to barnase results in enhanced solubility and altered pH stability. Protein Eng Des Sel (2004) 0.90
The putative "nucleation site" in human H-chain ferritin is not required for mineralization of the iron core. Biochemistry (2004) 0.89
Analysis of ferritin genes in Parkinson disease. Clin Chem Lab Med (2007) 0.89
Facilitated diffusion of iron(II) and dioxygen substrates into human H-chain ferritin. A fluorescence and absorbance study employing the ferroxidase center substitution Y34W. J Am Chem Soc (2008) 0.89
Role of iron and ferritin in TNFalpha-induced apoptosis in HeLa cells. FEBS Lett (2003) 0.88
Iron(II) and hydrogen peroxide detoxification by human H-chain ferritin. An EPR spin-trapping study. Biochemistry (2006) 0.87
New TFR2 mutations in young Italian patients with hemochromatosis. Haematologica (2008) 0.87
The sedimentation properties of ferritins. New insights and analysis of methods of nanoparticle preparation. Biochim Biophys Acta (2010) 0.87
Characterization of the l-ferritin variant 460InsA responsible of a hereditary ferritinopathy disorder. Neurobiol Dis (2006) 0.86
Correlation between the bone density recorded by a computerized implant motor and by a histomorphometric analysis: a preliminary in vitro study on bovine ribs. Clin Implant Dent Relat Res (2013) 0.86
Identification of two novel mutations in the 5'-untranslated region of H-ferritin using denaturing high performance liquid chromatography scanning. Haematologica (2003) 0.86
Comparative study between Hfe-/- and beta2m-/- mice: progression with age of iron status and liver pathology. Int J Exp Pathol (2006) 0.85
Defining metal ion inhibitor interactions with recombinant human H- and L-chain ferritins and site-directed variants: an isothermal titration calorimetry study. J Biol Inorg Chem (2003) 0.85
Ferritin--a mediator of apoptosis? J Cell Physiol (2007) 0.85
Mutations of ferritin H chain C-terminus produced by nucleotide insertions have altered stability and functional properties. J Biochem (2006) 0.84
Ferroportin gene silencing induces iron retention and enhances ferritin synthesis in human macrophages. Br J Haematol (2004) 0.84
Blotting analysis of native IRP1: a novel approach to distinguish the different forms of IRP1 in cells and tissues. Biochemistry (2004) 0.84
Mice lacking mitochondrial ferritin are more sensitive to doxorubicin-mediated cardiotoxicity. J Mol Med (Berl) (2014) 0.84
HFE gene mutations in a population of Italian Parkinson's disease patients. Parkinsonism Relat Disord (2008) 0.84
Recombinant human hepcidin expressed in Escherichia coli isolates as an iron containing protein. Blood Cells Mol Dis (2005) 0.82
Characterization of the H- and L-subunit ratios of ferritins by sodium dodecyl sulfate-capillary gel electrophoresis. Anal Biochem (2002) 0.82
Analysis of nucleotide variations in genes of iron management in patients of Parkinson's disease and other movement disorders. Parkinsons Dis (2010) 0.81
Inhibition of heme synthesis alters Amyloid Precursor Protein processing. J Neural Transm (Vienna) (2008) 0.81
Biology of ferritin in mammals: an update on iron storage, oxidative damage and neurodegeneration. Arch Toxicol (2014) 0.81
Kinetic studies of iron deposition catalyzed by recombinant human liver heavy and light ferritins and Azotobacter vinelandii bacterioferritin using O2 and H2O2 as oxidants. Biophys Chem (2005) 0.81
A novel deletion of the L-ferritin iron-responsive element responsible for severe hereditary hyperferritinaemia-cataract syndrome. Br J Haematol (2002) 0.80
Sequence variations in mitochondrial ferritin: distribution in healthy controls and different types of patients. Genet Test Mol Biomarkers (2010) 0.80
Coexistence of plasmonic and magnetic properties in Au89Fe11 nanoalloys. Nanoscale (2013) 0.80
Iron release from ferritin by flavin nucleotides. Biochim Biophys Acta (2013) 0.79
Self-assembling peptide and protein amyloids: from structure to tailored function in nanotechnology. Chem Soc Rev (2017) 0.78
A comparative Mössbauer study of the mineral cores of human H-chain ferritin employing dioxygen and hydrogen peroxide as iron oxidants. Biophys Chem (2007) 0.77
Denaturing HPLC analysis of DNA deletions and insertions. Hum Mutat (2003) 0.77
No evidence of relation between peripheral neuropathy and presence of hemochromatosis gene mutations in HIV-1-positive patients. J Acquir Immune Defic Syndr (2007) 0.77
A microfluidic platform for quantitative measurements of effective protein charges and single ion binding in solution. Phys Chem Chem Phys (2015) 0.77
Kinetic analysis of the multistep aggregation mechanism of monoclonal antibodies. J Phys Chem B (2014) 0.77
Biophysical approaches for the study of interactions between molecular chaperones and protein aggregates. Chem Commun (Camb) (2015) 0.76
Role of cosolutes in the aggregation kinetics of monoclonal antibodies. J Phys Chem B (2014) 0.76
Regional and cellular distribution of mitochondrial ferritin in the mouse brain. J Neurosci Res (2010) 0.76
Magnetic and relaxation properties of multifunctional polymer-based nanostructured bioferrofluids as MRI contrast agents. Magn Reson Med (2011) 0.76
Stability and gelation behavior of bovine serum albumin pre-aggregates in the presence of calcium chloride. Phys Chem Chem Phys (2012) 0.76
Superparamagnetic iron oxide nanoparticles stabilized by a poly(amidoamine)-rhenium complex as potential theranostic probe. Dalton Trans (2013) 0.75
A multiscale view of therapeutic protein aggregation: a colloid science perspective. Biotechnol J (2015) 0.75
Observing Xenopus laevis oocyte plasma membrane by Atomic Force Microscopy. Methods (2009) 0.75
Photoacoustic molecular imaging for in vivo liver iron quantitation. J Biomed Opt (2016) 0.75
Chemically and biologically harmless versus harmful ferritin/copper-metallothionein couples. Chemistry (2014) 0.75
Antiferritin VL homodimer binds human spleen ferritin with high specificity. J Struct Biol (2002) 0.75
Effect of surfactants on shear-induced gelation and gel morphology of soft strawberry-like particles. Langmuir (2011) 0.75
Mechanistic Origin of the Combined Effect of Surfaces and Mechanical Agitation on Amyloid Formation. ACS Nano (2017) 0.75
Correlation Between Bone Density and Instantaneous Torque at Implant Site Preparation: A Validation on Polyurethane Foam Blocks of a Device Assessing Density of Jawbones. Int J Oral Maxillofac Implants (2016) 0.75
A Molecular Logic Gate Enables Single-Molecule Imaging and Tracking of Lipids in Intracellular Domains. ACS Chem Biol (2020) 0.75
Mitochondrial ferritin deficiency reduces male fertility in mice. Reprod Fertil Dev (2017) 0.75