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Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes. Nature (2008) 10.11

Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol (2007) 9.36

Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature (2004) 7.42

Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice. J Cell Biol (2003) 5.74

DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes Dev (2008) 5.58

Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes. Genes Dev (2006) 4.97

ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation. Cell (2006) 4.61

Targets and dynamics of promoter DNA methylation during early mouse development. Nat Genet (2010) 4.27

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol (2011) 3.97

Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression. Mol Cell Biol (2005) 3.97

CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex. J Cell Biol (2005) 3.54

Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouse. Hum Mol Genet (2007) 3.27

Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells. J Cell Biol (2005) 3.05

Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development. Genes Dev (2008) 2.99

The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev Cell (2009) 2.96

Ethics. The ISSCR guidelines for human embryonic stem cell research. Science (2007) 2.62

Efficient establishment of human embryonic stem cell lines and long-term maintenance with stable karyotype by enzymatic bulk passage. Biochem Biophys Res Commun (2006) 2.52

Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity. Proc Natl Acad Sci U S A (2002) 2.34

Dynamic stage-specific changes in imprinted differentially methylated regions during early mammalian development and prevalence of non-CpG methylation in oocytes. Development (2011) 2.28

Efficient multicistronic expression of a transgene in human embryonic stem cells. Stem Cells (2007) 2.27

Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model. J Clin Invest (2005) 2.25

Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science (2011) 2.17

Highly efficient transient gene expression and gene targeting in primate embryonic stem cells with helper-dependent adenoviral vectors. Proc Natl Acad Sci U S A (2008) 2.17

Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and Nanog. Mol Cell Biol (2007) 2.15

Defining early lineage specification of human embryonic stem cells by the orchestrated balance of canonical Wnt/beta-catenin, Activin/Nodal and BMP signaling. Development (2008) 2.14

Tdrd1/Mtr-1, a tudor-related gene, is essential for male germ-cell differentiation and nuage/germinal granule formation in mice. Proc Natl Acad Sci U S A (2006) 2.09

Unregulated expression of the imprinted genes H19 and Igf2r in mouse uniparental fetuses. J Biol Chem (2002) 2.01

Pluripotential competence of cells associated with Nanog activity. Mech Dev (2005) 2.01

Homing of mouse spermatogonial stem cells to germline niche depends on beta1-integrin. Cell Stem Cell (2008) 1.98

Tsix silences Xist through modification of chromatin structure. Dev Cell (2005) 1.97

Multi-PDZ domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion molecule. J Biol Chem (2001) 1.96

External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers. J Exp Med (2009) 1.95

Efficient and scalable purification of cardiomyocytes from human embryonic and induced pluripotent stem cells by VCAM1 surface expression. PLoS One (2011) 1.95

MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline. Dev Cell (2011) 1.94

Establishment and characterization of cultured epithelial cells lacking expression of ZO-1. J Biol Chem (2004) 1.94

Generation of neural crest-derived peripheral neurons and floor plate cells from mouse and primate embryonic stem cells. Proc Natl Acad Sci U S A (2003) 1.93

Nanog expression in mouse germ cell development. Gene Expr Patterns (2005) 1.86

MVH in piRNA processing and gene silencing of retrotransposons. Genes Dev (2010) 1.84

A tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip. Nucleic Acids Res (2010) 1.83

Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution. PLoS Genet (2007) 1.79

Aberrant DNA methylation of imprinted loci in sperm from oligospermic patients. Hum Mol Genet (2007) 1.79

Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells. In Vitro Cell Dev Biol Anim (2010) 1.70

Laminin E8 fragments support efficient adhesion and expansion of dissociated human pluripotent stem cells. Nat Commun (2012) 1.70

Tight junctions in Schwann cells of peripheral myelinated axons: a lesson from claudin-19-deficient mice. J Cell Biol (2005) 1.69

Histone code modifications on pluripotential nuclei of reprogrammed somatic cells. Mol Cell Biol (2004) 1.67

Pathway for differentiation of human embryonic stem cells to vascular cell components and their potential for vascular regeneration. Arterioscler Thromb Vasc Biol (2007) 1.63

HLA-haplotype banking and iPS cells. Nat Biotechnol (2008) 1.61

A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions. Cell Rep (2012) 1.60

Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain composition, intracellular localization, and function in male germ cells in mice. Dev Biol (2006) 1.59

Progressive maturation in contracting cardiomyocytes derived from human embryonic stem cells: Qualitative effects on electrophysiological responses to drugs. Stem Cell Res (2010) 1.58

RNF17, a component of the mammalian germ cell nuage, is essential for spermiogenesis. Development (2005) 1.58

Mouse oocyte methylomes at base resolution reveal genome-wide accumulation of non-CpG methylation and role of DNA methyltransferases. PLoS Genet (2013) 1.57

Recombinant human laminin isoforms can support the undifferentiated growth of human embryonic stem cells. Biochem Biophys Res Commun (2008) 1.55

Mouse Tudor Repeat-1 (MTR-1) is a novel component of chromatoid bodies/nuages in male germ cells and forms a complex with snRNPs. Mech Dev (2003) 1.54

In vitro and in vivo characterization of pigment epithelial cells differentiated from primate embryonic stem cells. Invest Ophthalmol Vis Sci (2004) 1.52

Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions. Mol Biol Cell (2010) 1.51

De novo DNA methylation independent establishment of maternal imprint on X chromosome in mouse oocytes. Genesis (2008) 1.51

Ultrastructural characterization of spermatogenesis and its evolutionary conservation in the germline: germinal granules in mammals. Mol Cell Endocrinol (2008) 1.51

Crucial role of antisense transcription across the Xist promoter in Tsix-mediated Xist chromatin modification. Development (2007) 1.50

Compartmentalization established by claudin-11-based tight junctions in stria vascularis is required for hearing through generation of endocochlear potential. J Cell Sci (2004) 1.50

Claudin-2-deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules. Proc Natl Acad Sci U S A (2010) 1.49

Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia. J Cell Biol (2004) 1.47

LSR defines cell corners for tricellular tight junction formation in epithelial cells. J Cell Sci (2011) 1.47

Highly efficient differentiation and enrichment of spinal motor neurons derived from human and monkey embryonic stem cells. PLoS One (2009) 1.46

Adipogenic differentiation of human induced pluripotent stem cells: comparison with that of human embryonic stem cells. FEBS Lett (2009) 1.43

Loss of occludin affects tricellular localization of tricellulin. Mol Biol Cell (2008) 1.40

A method for the selection of human embryonic stem cell sublines with high replating efficiency after single-cell dissociation. Stem Cells (2006) 1.39

Re-investigation and RNA sequencing-based identification of genes with placenta-specific imprinted expression. Hum Mol Genet (2011) 1.39

De novo DNA methylation is dispensable for the initiation and propagation of X chromosome inactivation. Development (2004) 1.39

An atomic model of Zfp57 recognition of CpG methylation within a specific DNA sequence. Genes Dev (2012) 1.38

Establishment of novel embryonic stem cell lines derived from the common marmoset (Callithrix jacchus). Stem Cells (2005) 1.35

A proximal conserved repeat in the Xist gene is essential as a genomic element for X-inactivation in mouse. Development (2008) 1.35

Induction and enhancement of cardiac cell differentiation from mouse and human induced pluripotent stem cells with cyclosporin-A. PLoS One (2011) 1.33

Genomic imprinting in mammals: its life cycle, molecular mechanisms and reprogramming. Cell Res (2011) 1.33

Long-term culture of male germline stem cells from hamster testes. Biol Reprod (2007) 1.31

Tissue-specific demethylation in CpG-poor promoters during cellular differentiation. Hum Mol Genet (2011) 1.31

Associations between PIWI proteins and TDRD1/MTR-1 are critical for integrated subcellular localization in murine male germ cells. Genes Cells (2009) 1.27

Small RNA class transition from siRNA/piRNA to miRNA during pre-implantation mouse development. Nucleic Acids Res (2010) 1.27

Megaintestine in claudin-15-deficient mice. Gastroenterology (2007) 1.25

Stochastic imprinting in the progeny of Dnmt3L-/- females. Hum Mol Genet (2006) 1.24

PRDM14 suppresses expression of differentiation marker genes in human embryonic stem cells. Biochem Biophys Res Commun (2008) 1.24

Developing 100 ps-resolved X-ray structural analysis capabilities on beamline NW14A at the Photon Factory Advanced Ring. J Synchrotron Radiat (2007) 1.22

Meiotic and epigenetic aberrations in Dnmt3L-deficient male germ cells. Mol Reprod Dev (2006) 1.21

Tudor domain containing 7 (Tdrd7) is essential for dynamic ribonucleoprotein (RNP) remodeling of chromatoid bodies during spermatogenesis. Proc Natl Acad Sci U S A (2011) 1.21

Interaction of alpha1-adrenoceptor subtypes with different G proteins induces opposite effects on cardiac L-type Ca2+ channel. Circ Res (2008) 1.21

Targeted chromosome elimination from ES-somatic hybrid cells. Nat Methods (2006) 1.20

Gene targeting in human pluripotent stem cells with adeno-associated virus vectors. Biochem Biophys Res Commun (2009) 1.20

JACOP, a novel plaque protein localizing at the apical junctional complex with sequence similarity to cingulin. J Biol Chem (2004) 1.20

Conditional knockdown of Nanog induces apoptotic cell death in mouse migrating primordial germ cells. Development (2009) 1.20

Role of SOX2 in maintaining pluripotency of human embryonic stem cells. Genes Cells (2010) 1.19

Pluripotency of reprogrammed somatic genomes in embryonic stem hybrid cells. Dev Dyn (2003) 1.18

Three novel DNMT3B mutations in Japanese patients with ICF syndrome. Am J Med Genet (2002) 1.18

The E3 ubiquitin ligase LNX1p80 promotes the removal of claudins from tight junctions in MDCK cells. J Cell Sci (2009) 1.17

Human leukocyte antigen matching estimations in a hypothetical bank of human embryonic stem cell lines in the Japanese population for use in cell transplantation therapy. Stem Cells (2006) 1.16

Genetic evidence for Dnmt3a-dependent imprinting during oocyte growth obtained by conditional knockout with Zp3-Cre and complete exclusion of Dnmt3b by chimera formation. Genes Cells (2010) 1.14

Spermatogenesis from epiblast and primordial germ cells following transplantation into postnatal mouse testis. Development (2004) 1.14