Published in J Biol Chem on December 08, 2002
The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks. EMBO J (2006) 2.89
The Mus81 solution to resolution: generating meiotic crossovers without Holliday junctions. Genes Dev (2004) 2.89
Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes. Chromosoma (2011) 1.78
Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells. EMBO J (2003) 1.68
Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells. Proc Natl Acad Sci U S A (2013) 1.62
WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork. Mol Biol Cell (2003) 1.61
Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress. Genes Dev (2005) 1.60
Cooperative control of holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases. Mol Cell (2013) 1.57
Brh2 promotes a template-switching reaction enabling recombinational bypass of lesions during DNA synthesis. Mol Cell (2009) 1.51
Saccharomyces cerevisiae Mus81-Mms4 is a catalytic, DNA structure-selective endonuclease. Nucleic Acids Res (2008) 1.44
Mus81 cleavage of Holliday junctions: a failsafe for processing meiotic recombination intermediates? EMBO J (2007) 1.42
The involvement of Srs2 in post-replication repair and homologous recombination in fission yeast. Nucleic Acids Res (2004) 1.41
Cell cycle-dependent regulation of the nuclease activity of Mus81-Eme1/Mms4. Nucleic Acids Res (2012) 1.40
Requirement of Rrm3 helicase for repair of spontaneous DNA lesions in cells lacking Srs2 or Sgs1 helicase. Mol Cell Biol (2004) 1.40
MUS81 promotes common fragile site expression. Nat Cell Biol (2013) 1.40
DNA repair by a Rad22-Mus81-dependent pathway that is independent of Rhp51. Nucleic Acids Res (2004) 1.38
The role of DNA-PKcs and artemis in opening viral DNA hairpin termini in various tissues in mice. J Virol (2007) 1.35
Slx4 becomes phosphorylated after DNA damage in a Mec1/Tel1-dependent manner and is required for repair of DNA alkylation damage. Biochem J (2005) 1.32
Replication fork blockage by RTS1 at an ectopic site promotes recombination in fission yeast. EMBO J (2005) 1.32
Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway. J Cell Biol (2008) 1.31
Cleavage of stalled forks by fission yeast Mus81/Eme1 in absence of DNA replication checkpoint. Mol Biol Cell (2007) 1.28
The role of AtMUS81 in DNA repair and its genetic interaction with the helicase AtRecQ4A. Nucleic Acids Res (2006) 1.28
Rad54, the motor of homologous recombination. DNA Repair (Amst) (2010) 1.18
Mus81 endonuclease localizes to nucleoli and to regions of DNA damage in human S-phase cells. Mol Biol Cell (2003) 1.17
RNA interference inhibition of Mus81 reduces mitotic recombination in human cells. Mol Biol Cell (2003) 1.17
Roles of SGS1, MUS81, and RAD51 in the repair of lagging-strand replication defects in Saccharomyces cerevisiae. Curr Genet (2005) 1.14
Fbh1 limits Rad51-dependent recombination at blocked replication forks. Mol Cell Biol (2009) 1.13
Evidence that the S.cerevisiae Sgs1 protein facilitates recombinational repair of telomeres during senescence. Nucleic Acids Res (2006) 1.10
A junction branch point adjacent to a DNA backbone nick directs substrate cleavage by Saccharomyces cerevisiae Mus81-Mms4. Nucleic Acids Res (2009) 1.06
Rad22Rad52-dependent repair of ribosomal DNA repeats cleaved by Slx1-Slx4 endonuclease. Mol Biol Cell (2006) 1.05
Crystal structure of the Mus81-Eme1 complex. Genes Dev (2008) 1.04
The human Holliday junction resolvase GEN1 rescues the meiotic phenotype of a Schizosaccharomyces pombe mus81 mutant. Nucleic Acids Res (2009) 1.03
Cooperativity of Mus81.Mms4 with Rad54 in the resolution of recombination and replication intermediates. J Biol Chem (2009) 1.01
RAD5A, RECQ4A, and MUS81 have specific functions in homologous recombination and define different pathways of DNA repair in Arabidopsis thaliana. Plant Cell (2010) 0.99
Mms22 preserves genomic integrity during DNA replication in Schizosaccharomyces pombe. Genetics (2007) 0.98
Cooperation of RAD51 and RAD54 in regression of a model replication fork. Nucleic Acids Res (2010) 0.97
Genetic and functional interactions between Mus81-Mms4 and Rad27. Nucleic Acids Res (2010) 0.92
Temporal regulation of the Mus81-Mms4 endonuclease ensures cell survival under conditions of DNA damage. Nucleic Acids Res (2013) 0.91
The multifunctional SNM1 gene family: not just nucleases. Future Oncol (2010) 0.91
Regulation of Mus81-Eme1 Holliday junction resolvase in response to DNA damage. Nat Struct Mol Biol (2013) 0.89
Mus81-Eme1-dependent and -independent crossovers form in mitotic cells during double-strand break repair in Schizosaccharomyces pombe. Mol Cell Biol (2007) 0.89
Two distinct MUS81-EME1 complexes from Arabidopsis process Holliday junctions. Plant Physiol (2009) 0.87
Mus81 functions in the quality control of replication forks at the rDNA and is involved in the maintenance of rDNA repeat number in Saccharomyces cerevisiae. Mutat Res (2007) 0.86
Substrate specificity of the MUS81-EME2 structure selective endonuclease. Nucleic Acids Res (2013) 0.83
Biochemistry of Meiotic Recombination: Formation, Processing, and Resolution of Recombination Intermediates. Genome Dyn Stab (2008) 0.83
Survival of the replication checkpoint deficient cells requires MUS81-RAD52 function. PLoS Genet (2013) 0.83
The ATPase activity of Fml1 is essential for its roles in homologous recombination and DNA repair. Nucleic Acids Res (2012) 0.82
Crystal structures of the structure-selective nuclease Mus81-Eme1 bound to flap DNA substrates. EMBO J (2014) 0.81
Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein. Nucleic Acids Res (2013) 0.81
Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates. Nucleic Acids Res (2015) 0.81
Base excision repair of oxidative DNA damage coupled with removal of a CAG repeat hairpin attenuates trinucleotide repeat expansion. Nucleic Acids Res (2014) 0.80
A physiological significance of the functional interaction between Mus81 and Rad27 in homologous recombination repair. Nucleic Acids Res (2015) 0.78
Effect of single-strand break on branch migration and folding dynamics of Holliday junctions. Biophys J (2010) 0.76
The Intra-S Checkpoint Responses to DNA Damage. Genes (Basel) (2017) 0.76
Esc2 promotes Mus81 complex-activity via its SUMO-like and DNA binding domains. Nucleic Acids Res (2016) 0.75
Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response. Oncotarget (2015) 0.75
Resolvase OsGEN1 mediates DNA repair by homologous recombination. Plant Physiol (2017) 0.75
MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells. Nat Commun (2017) 0.75
Generating crossovers by resolution of nicked Holliday junctions: a role for Mus81-Eme1 in meiosis. Mol Cell (2003) 3.29
Mus81-Eme1 and Rqh1 involvement in processing stalled and collapsed replication forks. J Biol Chem (2002) 2.97
A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability. Mol Cell (2010) 2.36
The FANCM ortholog Fml1 promotes recombination at stalled replication forks and limits crossing over during DNA double-strand break repair. Mol Cell (2008) 2.19
The F-Box DNA helicase Fbh1 prevents Rhp51-dependent recombination without mediator proteins. Mol Cell Biol (2005) 1.82
Mus81 cleavage of Holliday junctions: a failsafe for processing meiotic recombination intermediates? EMBO J (2007) 1.42
DNA repair by a Rad22-Mus81-dependent pathway that is independent of Rhp51. Nucleic Acids Res (2004) 1.38
Replication fork blockage by RTS1 at an ectopic site promotes recombination in fission yeast. EMBO J (2005) 1.32
The fission yeast FANCM ortholog directs non-crossover recombination during meiosis. Science (2012) 1.26
Fbh1 limits Rad51-dependent recombination at blocked replication forks. Mol Cell Biol (2009) 1.13
The DNA helicase Pfh1 promotes fork merging at replication termination sites to ensure genome stability. Genes Dev (2012) 1.04
Ultrafine anaphase bridges, broken DNA and illegitimate recombination induced by a replication fork barrier. Nucleic Acids Res (2011) 1.01
A general role of the DNA glycosylase Nth1 in the abasic sites cleavage step of base excision repair in Schizosaccharomyces pombe. Nucleic Acids Res (2004) 1.00
Alternative induction of meiotic recombination from single-base lesions of DNA deaminases. Genetics (2009) 0.89
MHF1-2/CENP-S-X performs distinct roles in centromere metabolism and genetic recombination. Open Biol (2013) 0.88
A failure of meiotic chromosome segregation in a fbh1Delta mutant correlates with persistent Rad51-DNA associations. Nucleic Acids Res (2010) 0.83
Risk factors and seroprevalence of markers for hepatitis A, B and C in persons subject to homelessness in inner Sydney. Aust N Z J Public Health (2007) 0.83
Nurse specialist treatment of eye emergencies: five year follow up study of quality and effectiveness. Int Emerg Nurs (2009) 0.80
SAR of a novel 'Anthranilamide Like' series of VEGFR-2, multi protein kinase inhibitors for the treatment of cancer. Bioorg Med Chem Lett (2007) 0.79
Slx8 removes Pli1-dependent protein-SUMO conjugates including SUMOylated topoisomerase I to promote genome stability. PLoS One (2013) 0.77
Thinking the unthinkable: does mental health nursing have a future? J Psychiatr Ment Health Nurs (2009) 0.75
Patient perspective: what do palliative care patients think about their care? Int J Palliat Nurs (2008) 0.75