Published in Mol Cell on October 10, 2008
Mechanisms of change in gene copy number. Nat Rev Genet (2009) 9.01
Maintaining genome stability at the replication fork. Nat Rev Mol Cell Biol (2010) 5.88
How the fanconi anemia pathway guards the genome. Annu Rev Genet (2009) 4.94
Regulation of homologous recombination in eukaryotes. Annu Rev Genet (2010) 4.33
A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair. Mol Cell (2010) 3.51
Expanded roles of the Fanconi anemia pathway in preserving genomic stability. Genes Dev (2010) 3.33
Homologous recombination and its regulation. Nucleic Acids Res (2012) 2.44
MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM. Mol Cell (2010) 2.40
A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability. Mol Cell (2010) 2.36
Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M. Blood (2009) 2.33
Replication fork reversal and the maintenance of genome stability. Nucleic Acids Res (2009) 2.06
DNA damage tolerance: when it's OK to make mistakes. Nat Chem Biol (2009) 2.04
DNA interstrand crosslink repair in mammalian cells: step by step. Crit Rev Biochem Mol Biol (2010) 1.82
ATR activation and replication fork restart are defective in FANCM-deficient cells. EMBO J (2010) 1.75
The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair. Nucleic Acids Res (2009) 1.65
Brh2 promotes a template-switching reaction enabling recombinational bypass of lesions during DNA synthesis. Mol Cell (2009) 1.51
Role of double-stranded DNA translocase activity of human HLTF in replication of damaged DNA. Mol Cell Biol (2009) 1.50
Rescuing stalled or damaged replication forks. Cold Spring Harb Perspect Biol (2013) 1.34
Interplay between the Smc5/6 complex and the Mph1 helicase in recombinational repair. Proc Natl Acad Sci U S A (2009) 1.31
FANCM regulates DNA chain elongation and is stabilized by S-phase checkpoint signalling. EMBO J (2009) 1.31
Mechanisms and regulation of mitotic recombination in Saccharomyces cerevisiae. Genetics (2014) 1.27
The fission yeast FANCM ortholog directs non-crossover recombination during meiosis. Science (2012) 1.26
The Smc5/6 complex and Esc2 influence multiple replication-associated recombination processes in Saccharomyces cerevisiae. Mol Biol Cell (2010) 1.22
Ubiquitylation and the Fanconi anemia pathway. FEBS Lett (2011) 1.21
Functional significance of the Rad51-Srs2 complex in Rad51 presynaptic filament disruption. Nucleic Acids Res (2009) 1.21
Fbh1 limits Rad51-dependent recombination at blocked replication forks. Mol Cell Biol (2009) 1.13
The Fanconi anemia ortholog FANCM ensures ordered homologous recombination in both somatic and meiotic cells in Arabidopsis. Plant Cell (2012) 1.12
Homologous recombination-dependent rescue of deficiency in the structural maintenance of chromosomes (Smc) 5/6 complex. J Biol Chem (2010) 1.05
Restriction of replication fork regression activities by a conserved SMC complex. Mol Cell (2014) 1.04
Heteroduplex DNA position defines the roles of the Sgs1, Srs2, and Mph1 helicases in promoting distinct recombination outcomes. PLoS Genet (2013) 1.04
Impediments to replication fork movement: stabilisation, reactivation and genome instability. Chromosoma (2013) 1.02
Ultrafine anaphase bridges, broken DNA and illegitimate recombination induced by a replication fork barrier. Nucleic Acids Res (2011) 1.01
Processing of DNA structures via DNA unwinding and branch migration by the S. cerevisiae Mph1 protein. DNA Repair (Amst) (2011) 1.01
RecG protein and single-strand DNA exonucleases avoid cell lethality associated with PriA helicase activity in Escherichia coli. Genetics (2010) 1.00
DNA repair and global sumoylation are regulated by distinct Ubc9 noncovalent complexes. Mol Cell Biol (2011) 0.98
Cleavage of a model DNA replication fork by a Type I restriction endonuclease. Nucleic Acids Res (2009) 0.97
The BLM dissolvasome in DNA replication and repair. Cell Mol Life Sci (2013) 0.97
Resolving branched DNA intermediates with structure-specific nucleases during replication in eukaryotes. Chromosoma (2013) 0.95
Rad5-dependent DNA repair functions of the Saccharomyces cerevisiae FANCM protein homolog Mph1. J Biol Chem (2012) 0.95
Components of a Fanconi-like pathway control Pso2-independent DNA interstrand crosslink repair in yeast. PLoS Genet (2012) 0.93
Template switching during break-induced replication is promoted by the Mph1 helicase in Saccharomyces cerevisiae. Genetics (2014) 0.93
A prototypical Fanconi anemia pathway in lower eukaryotes? Cell Cycle (2012) 0.92
Mph1 and Mus81-Mms4 prevent aberrant processing of mitotic recombination intermediates. Mol Cell (2013) 0.91
Investigations of homologous recombination pathways and their regulation. Yale J Biol Med (2013) 0.90
Mph1 requires mismatch repair-independent and -dependent functions of MutSalpha to regulate crossover formation during homologous recombination repair. Nucleic Acids Res (2010) 0.90
The conserved Fanconi anemia nuclease Fan1 and the SUMO E3 ligase Pli1 act in two novel Pso2-independent pathways of DNA interstrand crosslink repair in yeast. DNA Repair (Amst) (2013) 0.88
MHF1-2/CENP-S-X performs distinct roles in centromere metabolism and genetic recombination. Open Biol (2013) 0.88
FANCM-associated proteins MHF1 and MHF2, but not the other Fanconi anemia factors, limit meiotic crossovers. Nucleic Acids Res (2014) 0.87
Regulation of DNA pairing in homologous recombination. Cold Spring Harb Perspect Biol (2014) 0.86
Genetic controls of DNA damage avoidance in response to acetaldehyde in fission yeast. Cell Cycle (2016) 0.86
The extent of error-prone replication restart by homologous recombination is controlled by Exo1 and checkpoint proteins. J Cell Sci (2014) 0.86
A failure of meiotic chromosome segregation in a fbh1Delta mutant correlates with persistent Rad51-DNA associations. Nucleic Acids Res (2010) 0.83
Biochemical studies of the Saccharomyces cerevisiae Mph1 helicase on junction-containing DNA structures. Nucleic Acids Res (2011) 0.82
Functional analysis of DNA replication fork reversal catalyzed by Mycobacterium tuberculosis RuvAB proteins. J Biol Chem (2011) 0.82
Drosophila FANCM helicase prevents spontaneous mitotic crossovers generated by the MUS81 and SLX1 nucleases. Genetics (2014) 0.82
Faithful after break-up: suppression of chromosomal translocations. Cell Mol Life Sci (2009) 0.82
The ATPase activity of Fml1 is essential for its roles in homologous recombination and DNA repair. Nucleic Acids Res (2012) 0.82
Functions and regulation of the multitasking FANCM family of DNA motor proteins. Genes Dev (2015) 0.82
The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes. Nat Commun (2014) 0.81
Nse1-dependent recruitment of Smc5/6 to lesion-containing loci contributes to the repair defects of mutant complexes. Mol Biol Cell (2011) 0.81
The histone-fold complex MHF is remodeled by FANCM to recognize branched DNA and protect genome stability. Cell Res (2014) 0.80
Cellular location and activity of Escherichia coli RecG proteins shed light on the function of its structurally unresolved C-terminus. Nucleic Acids Res (2014) 0.80
Roles of DNA helicases in the mediation and regulation of homologous recombination. Adv Exp Med Biol (2013) 0.79
Choices have consequences: the nexus between DNA repair pathways and genomic instability in cancer. Clin Transl Med (2016) 0.79
The chromatin assembly factor 1 promotes Rad51-dependent template switches at replication forks by counteracting D-loop disassembly by the RecQ-type helicase Rqh1. PLoS Biol (2014) 0.79
Selective modulation of the functions of a conserved DNA motor by a histone fold complex. Genes Dev (2015) 0.79
Essential domains of Schizosaccharomyces pombe Rad8 required for DNA damage response. G3 (Bethesda) (2014) 0.79
MTE1 Functions with MPH1 in Double-Strand Break Repair. Genetics (2016) 0.78
Multiple regulation of Rad51-mediated homologous recombination by fission yeast Fbh1. PLoS Genet (2014) 0.78
Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells. Genome Med (2014) 0.77
Differential regulation of the anti-crossover and replication fork regression activities of Mph1 by Mte1. Genes Dev (2016) 0.77
The RecQ DNA helicase Rqh1 constrains Exonuclease 1-dependent recombination at stalled replication forks. Sci Rep (2016) 0.77
Slx8 removes Pli1-dependent protein-SUMO conjugates including SUMOylated topoisomerase I to promote genome stability. PLoS One (2013) 0.77
Recombination occurs within minutes of replication blockage by RTS1 producing restarted forks that are prone to collapse. Elife (2015) 0.77
Biochemical Activities and Genetic Functions of the Drosophila melanogaster Fancm Helicase in DNA Repair. Genetics (2016) 0.76
Human Cell Assays for Synthesis-Dependent Strand Annealing and Crossing over During Double-Strand Break Repair. G3 (Bethesda) (2017) 0.76
Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombination. Nucleic Acids Res (2014) 0.76
Recovery from the DNA Replication Checkpoint. Genes (Basel) (2016) 0.75
Differential requirement of Srs2 helicase and Rad51 displacement activities in replication of hairpin-forming CAG/CTG repeats. Nucleic Acids Res (2017) 0.75
Involvement of Schizosaccharomyces pombe rrp1+ and rrp2+ in the Srs2- and Swi5/Sfr1-dependent pathway in response to DNA damage and replication inhibition. Nucleic Acids Res (2013) 0.75
DNA damage response and cancer therapeutics through the lens of the Fanconi Anemia DNA repair pathway. Cell Commun Signal (2017) 0.75
Mechanism of eukaryotic homologous recombination. Annu Rev Biochem (2008) 8.86
Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins. Nat Rev Genet (2007) 7.29
Yeast recombination: the association between double-strand gap repair and crossing-over. Proc Natl Acad Sci U S A (1983) 6.10
Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast. Cell (2003) 5.45
The Bloom's syndrome gene product promotes branch migration of holliday junctions. Proc Natl Acad Sci U S A (2000) 4.67
A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M. Nat Genet (2005) 4.57
A model for replication repair in mammalian cells. J Mol Biol (1976) 3.78
Recombinational repair and restart of damaged replication forks. Nat Rev Mol Cell Biol (2002) 3.64
Yeast Rad5 protein required for postreplication repair has a DNA helicase activity specific for replication fork regression. Mol Cell (2007) 3.51
Generating crossovers by resolution of nicked Holliday junctions: a role for Mus81-Eme1 in meiosis. Mol Cell (2003) 3.29
Modulation of RNA polymerase by (p)ppGpp reveals a RecG-dependent mechanism for replication fork progression. Cell (2000) 2.97
The Fanconi anemia protein FANCM can promote branch migration of Holliday junctions and replication forks. Mol Cell (2008) 2.68
The Bloom's syndrome helicase can promote the regression of a model replication fork. J Biol Chem (2006) 2.65
The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway. Nat Struct Mol Biol (2005) 2.55
Mobile D-loops are a preferred substrate for the Bloom's syndrome helicase. Nucleic Acids Res (2006) 2.48
Rad54 protein promotes branch migration of Holliday junctions. Nature (2006) 2.08
Uncoupling of leading- and lagging-strand DNA replication during lesion bypass in vivo. Science (2003) 2.02
The RecQ helicase-topoisomerase III-Rmi1 complex: a DNA structure-specific 'dissolvasome'? Trends Biochem Sci (2007) 1.97
RecA-dependent recovery of arrested DNA replication forks. Annu Rev Genet (2003) 1.85
Exploring the roles of Mus81-Eme1/Mms4 at perturbed replication forks. DNA Repair (Amst) (2007) 1.76
Yeast MPH1 gene functions in an error-free DNA damage bypass pathway that requires genes from Homologous recombination, but not from postreplicative repair. Genetics (2004) 1.76
Saccharomyces cerevisiae MPH1 gene, required for homologous recombination-mediated mutation avoidance, encodes a 3' to 5' DNA helicase. J Biol Chem (2005) 1.69
FANCM of the Fanconi anemia core complex is required for both monoubiquitination and DNA repair. Hum Mol Genet (2008) 1.65
The Srs2 helicase activity is stimulated by Rad51 filaments on dsDNA: implications for crossover incidence during mitotic recombination. Mol Cell (2008) 1.62
Rad54 dissociates homologous recombination intermediates by branch migration. Nat Struct Mol Biol (2007) 1.61
Smc5/6 is required for repair at collapsed replication forks. Mol Cell Biol (2006) 1.51
Role for the fission yeast RecQ helicase in DNA repair in G2. Mol Cell Biol (2003) 1.45
The involvement of Srs2 in post-replication repair and homologous recombination in fission yeast. Nucleic Acids Res (2004) 1.41
The RecG branch migration protein of Escherichia coli dissociates R-loops. J Mol Biol (1996) 1.38
DNA repair by a Rad22-Mus81-dependent pathway that is independent of Rhp51. Nucleic Acids Res (2004) 1.38
Replication fork blockage by RTS1 at an ectopic site promotes recombination in fission yeast. EMBO J (2005) 1.32
Spontaneous and double-strand break-induced recombination, and gene conversion tract lengths, are differentially affected by overexpression of wild-type or ATPase-defective yeast Rad54. Nucleic Acids Res (2002) 0.94
Crossover promotion and prevention. Biochem Soc Trans (2006) 0.86
Generating crossovers by resolution of nicked Holliday junctions: a role for Mus81-Eme1 in meiosis. Mol Cell (2003) 3.29
Mus81-Eme1 and Rqh1 involvement in processing stalled and collapsed replication forks. J Biol Chem (2002) 2.97
JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F-positive essential thrombocythemia. Blood (2010) 2.83
A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability. Mol Cell (2010) 2.36
Infarct volume is a major determiner of post-stroke immune cell function and susceptibility to infection. Stroke (2009) 2.28
The F-Box DNA helicase Fbh1 prevents Rhp51-dependent recombination without mediator proteins. Mol Cell Biol (2005) 1.82
Exploring the roles of Mus81-Eme1/Mms4 at perturbed replication forks. DNA Repair (Amst) (2007) 1.76
Cleavage of model replication forks by fission yeast Mus81-Eme1 and budding yeast Mus81-Mms4. J Biol Chem (2002) 1.76
Yeast nuclear envelope subdomains with distinct abilities to resist membrane expansion. Mol Biol Cell (2006) 1.48
Mus81 cleavage of Holliday junctions: a failsafe for processing meiotic recombination intermediates? EMBO J (2007) 1.42
The involvement of Srs2 in post-replication repair and homologous recombination in fission yeast. Nucleic Acids Res (2004) 1.41
DNA repair by a Rad22-Mus81-dependent pathway that is independent of Rhp51. Nucleic Acids Res (2004) 1.38
Replication fork blockage by RTS1 at an ectopic site promotes recombination in fission yeast. EMBO J (2005) 1.32
The fission yeast FANCM ortholog directs non-crossover recombination during meiosis. Science (2012) 1.26
Fbh1 limits Rad51-dependent recombination at blocked replication forks. Mol Cell Biol (2009) 1.13
The DNA helicase Pfh1 promotes fork merging at replication termination sites to ensure genome stability. Genes Dev (2012) 1.04
The human Holliday junction resolvase GEN1 rescues the meiotic phenotype of a Schizosaccharomyces pombe mus81 mutant. Nucleic Acids Res (2009) 1.03
Ultrafine anaphase bridges, broken DNA and illegitimate recombination induced by a replication fork barrier. Nucleic Acids Res (2011) 1.01
A general role of the DNA glycosylase Nth1 in the abasic sites cleavage step of base excision repair in Schizosaccharomyces pombe. Nucleic Acids Res (2004) 1.00
Coiled-coil interactions are required for post-Golgi R-SNARE trafficking. EMBO Rep (2009) 0.98
Biochemical characterization and DNA repair pathway interactions of Mag1-mediated base excision repair in Schizosaccharomyces pombe. Nucleic Acids Res (2005) 0.96
Atorvastatin partially prevents an inflammatory barrier breakdown of cultured human brain endothelial cells at a pharmacologically relevant concentration. J Neurochem (2007) 0.94
Roles of Hop1 and Mek1 in meiotic chromosome pairing and recombination partner choice in Schizosaccharomyces pombe. Mol Cell Biol (2010) 0.92
Differential activation of M26-containing meiotic recombination hot spots in Schizosaccharomyces pombe. Genetics (2005) 0.90
Correction of proliferation and drug sensitivity defects in the progeroid Werner's Syndrome by Holliday junction resolution. Rejuvenation Res (2007) 0.89
Alternative induction of meiotic recombination from single-base lesions of DNA deaminases. Genetics (2009) 0.89
The role of the SAP motif in promoting Holliday junction binding and resolution by SpCCE1. J Biol Chem (2003) 0.89
MHF1-2/CENP-S-X performs distinct roles in centromere metabolism and genetic recombination. Open Biol (2013) 0.88
Monitoring homologous recombination following replication fork perturbation in the fission yeast Schizosaccharomyces pombe. Methods Mol Biol (2009) 0.87
Reduced efficacy of circulating costimulatory cells after focal cerebral ischemia. Stroke (2011) 0.86
Junctions on the road to cancer. Nat Struct Mol Biol (2004) 0.85
Analysis of Schizosaccharomyces pombe meiosis by nuclear spreading. Methods Mol Biol (2009) 0.85
Polarization-independent phase modulation using a blue-phase liquid crystal over silicon device. Appl Opt (2014) 0.84
A failure of meiotic chromosome segregation in a fbh1Delta mutant correlates with persistent Rad51-DNA associations. Nucleic Acids Res (2010) 0.83
UV irradiation causes the loss of viable mitotic recombinants in Schizosaccharomyces pombe cells lacking the G(2)/M DNA damage checkpoint. Genetics (2002) 0.83
Structure-specific endonucleases xpf and mus81 play overlapping but essential roles in DNA repair by homologous recombination. Cancer Res (2013) 0.83
Efficient second strand cleavage during Holliday junction resolution by RuvC requires both increased junction flexibility and an exposed 5' phosphate. PLoS One (2009) 0.83
The ATPase activity of Fml1 is essential for its roles in homologous recombination and DNA repair. Nucleic Acids Res (2012) 0.82
Chromosome associations in budding yeast caused by integrated tandemly repeated transgenes. J Cell Sci (2002) 0.82
Mug20, a novel protein associated with linear elements in fission yeast meiosis. Curr Genet (2012) 0.81
Emerging roles for centromere-associated proteins in DNA repair and genetic recombination. Biochem Soc Trans (2013) 0.79
Slx8 removes Pli1-dependent protein-SUMO conjugates including SUMOylated topoisomerase I to promote genome stability. PLoS One (2013) 0.77
How not to get cross(ed): a novel role for FANCM orthologs in meiotic recombination. Cell Cycle (2012) 0.76
Laser-induced erasable patterns in a N* liquid crystal on an iron doped lithium niobate surface. Opt Express (2017) 0.75