Reduced sodium channel density, altered voltage dependence of inactivation, and increased susceptibility to seizures in mice lacking sodium channel beta 2-subunits.

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Published in Proc Natl Acad Sci U S A on December 12, 2002

Authors

Chunling Chen1, Vandana Bharucha, Yuan Chen, Ruth E Westenbroek, Angus Brown, Jyoti Dhar Malhotra, Dorothy Jones, Christy Avery, Patrick J Gillespie, Kristin A Kazen-Gillespie, Katie Kazarinova-Noyes, Peter Shrager, Thomas L Saunders, Robert L Macdonald, Bruce R Ransom, Todd Scheuer, William A Catterall, Lori L Isom

Author Affiliations

1: Departments of Pharmacology and Neurology, and Transgenic Animal Model Core Laboratory, University of Michigan, Ann Arbor, MI 48109, USA.

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