Published in J Cell Sci on January 15, 2003
Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation. EMBO J (2004) 3.31
Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells. PLoS Biol (2007) 3.01
WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility. EMBO J (2003) 1.98
A WAVE-1 and WRP signaling complex regulates spine density, synaptic plasticity, and memory. J Neurosci (2007) 1.97
Dynamics of membranes driven by actin polymerization. Biophys J (2005) 1.50
The ability of LCRMP-1 to promote cancer invasion by enhancing filopodia formation is antagonized by CRMP-1. J Clin Invest (2011) 1.44
Abl interactor 1 (Abi-1) wave-binding and SNARE domains regulate its nucleocytoplasmic shuttling, lamellipodium localization, and wave-1 levels. Mol Cell Biol (2004) 1.38
DISTORTED3/SCAR2 is a putative arabidopsis WAVE complex subunit that activates the Arp2/3 complex and is required for epidermal morphogenesis. Plant Cell (2005) 1.30
WAVE1 controls neuronal activity-induced mitochondrial distribution in dendritic spines. Proc Natl Acad Sci U S A (2008) 1.28
The WASP and WAVE family proteins. Genome Biol (2009) 1.18
Inclusion of Scar/WAVE3 in a similar complex to Scar/WAVE1 and 2. BMC Cell Biol (2005) 1.16
Rapid de-localization of actin leading edge components with BDM treatment. BMC Cell Biol (2003) 1.07
mDia1 and WAVE2 proteins interact directly with IRSp53 in filopodia and are involved in filopodium formation. J Biol Chem (2011) 1.06
CIP4 coordinates with phospholipids and actin-associated proteins to localize to the protruding edge and produce actin ribs and veils. J Cell Sci (2013) 1.00
The Nance-Horan syndrome protein encodes a functional WAVE homology domain (WHD) and is important for co-ordinating actin remodelling and maintaining cell morphology. Hum Mol Genet (2010) 0.99
The actin-binding protein UNC-115/abLIM controls formation of lamellipodia and filopodia and neuronal morphogenesis in Caenorhabditis elegans. Mol Cell Biol (2005) 0.94
Signaling pathways controlling the phosphorylation state of WAVE1, a regulator of actin polymerization. J Neurochem (2010) 0.93
The N-terminus of Dictyostelium Scar interacts with Abi and HSPC300 and is essential for proper regulation and function. Mol Biol Cell (2007) 0.89
Phosphoinositide-binding interface proteins involved in shaping cell membranes. Proc Jpn Acad Ser B Phys Biol Sci (2010) 0.84
Membrane-targeted WAVE mediates photoreceptor axon targeting in the absence of the WAVE complex in Drosophila. Mol Biol Cell (2011) 0.83
Ultrastructural abnormalities in CA1 hippocampus caused by deletion of the actin regulator WAVE-1. PLoS One (2013) 0.82
Actin-independent behavior and membrane deformation exhibited by the four-transmembrane protein M6a. PLoS One (2011) 0.82
A novel role for WAVE1 in controlling actin network growth rate and architecture. Mol Biol Cell (2014) 0.79
Contribution of the LIM domain and nebulin-repeats to the interaction of Lasp-2 with actin filaments and focal adhesions. PLoS One (2009) 0.78
A neural-specific splicing event generates an active form of the Wiskott-Aldrich syndrome protein. EMBO Rep (2004) 0.78
Retrolinkin recruits the WAVE1 protein complex to facilitate BDNF-induced TrkB endocytosis and dendrite outgrowth. Mol Biol Cell (2016) 0.76
SH2B1 orchestrates signaling events to filopodium formation during neurite outgrowth. Commun Integr Biol (2015) 0.75
Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin. J Cell Biol (2005) 4.75
Curved EFC/F-BAR-domain dimers are joined end to end into a filament for membrane invagination in endocytosis. Cell (2007) 4.73
Regulation of cancer cell motility through actin reorganization. Cancer Sci (2005) 3.87
Coordination between the actin cytoskeleton and membrane deformation by a novel membrane tubulation domain of PCH proteins is involved in endocytosis. J Cell Biol (2006) 3.17
The thioredoxin-related redox-regulating protein nucleoredoxin inhibits Wnt-beta-catenin signalling through dishevelled. Nat Cell Biol (2006) 2.83
Differential roles of WAVE1 and WAVE2 in dorsal and peripheral ruffle formation for fibroblast cell migration. Dev Cell (2003) 2.56
A novel serum metabolomics-based diagnostic approach to pancreatic cancer. Cancer Epidemiol Biomarkers Prev (2013) 2.34
Sequential signals toward podosome formation in NIH-src cells. J Cell Biol (2008) 2.18
Nebulin and N-WASP cooperate to cause IGF-1-induced sarcomeric actin filament formation. Science (2010) 2.14
Synaptopodin protects against proteinuria by disrupting Cdc42:IRSp53:Mena signaling complexes in kidney podocytes. Am J Pathol (2007) 2.13
WAVE2 is required for directed cell migration and cardiovascular development. Nature (2003) 2.09
Essential role of neural Wiskott-Aldrich syndrome protein in podosome formation and degradation of extracellular matrix in src-transformed fibroblasts. Cancer Res (2002) 1.96
PtdIns(3,4,5)P3 binding is necessary for WAVE2-induced formation of lamellipodia. Nat Cell Biol (2004) 1.92
Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex. J Biol Chem (2007) 1.85
Myotubularin regulates the function of the late endosome through the gram domain-phosphatidylinositol 3,5-bisphosphate interaction. J Biol Chem (2004) 1.73
Focal adhesion kinase regulation of N-WASP subcellular localization and function. J Biol Chem (2003) 1.70
Arp2/3 activity is necessary for efficient formation of E-cadherin adhesive contacts. J Biol Chem (2004) 1.66
CRMP-2 is involved in kinesin-1-dependent transport of the Sra-1/WAVE1 complex and axon formation. Mol Cell Biol (2005) 1.64
Regulation of actin dynamics by WASP family proteins. J Biochem (2003) 1.63
Sustained activation of N-WASP through phosphorylation is essential for neurite extension. Dev Cell (2002) 1.58
The RAC binding domain/IRSp53-MIM homology domain of IRSp53 induces RAC-dependent membrane deformation. J Biol Chem (2006) 1.56
Optimization of WAVE2 complex-induced actin polymerization by membrane-bound IRSp53, PIP(3), and Rac. J Cell Biol (2006) 1.50
Recombinant phospholipase Czeta has high Ca2+ sensitivity and induces Ca2+ oscillations in mouse eggs. J Biol Chem (2003) 1.46
Rac-WAVE2 signaling is involved in the invasive and metastatic phenotypes of murine melanoma cells. Oncogene (2005) 1.45
A novel serum metabolomics-based diagnostic approach for colorectal cancer. PLoS One (2012) 1.40
IRSp53 is colocalised with WAVE2 at the tips of protruding lamellipodia and filopodia independently of Mena. J Cell Sci (2003) 1.40
Small GTPase Rah/Rab34 is associated with membrane ruffles and macropinosomes and promotes macropinosome formation. J Biol Chem (2002) 1.40
Rac-WAVE-mediated actin reorganization is required for organization and maintenance of cell-cell adhesion. J Cell Sci (2006) 1.39
Essential role of the C. elegans Arp2/3 complex in cell migration during ventral enclosure. J Cell Sci (2003) 1.33
A metabolomic approach to lung cancer. Lung Cancer (2011) 1.30
The tyrosine kinase Fer is a downstream target of the PLD-PA pathway that regulates cell migration. Sci Signal (2009) 1.29
Phosphoinositide-binding domains: Functional units for temporal and spatial regulation of intracellular signalling. Cell Signal (2002) 1.28
IRSp53/Eps8 complex is important for positive regulation of Rac and cancer cell motility/invasiveness. Cancer Res (2004) 1.27
A distinct pool of phosphatidylinositol 4,5-bisphosphate in caveolae revealed by a nanoscale labeling technique. Proc Natl Acad Sci U S A (2009) 1.25
Small GTPase Tc10 and its homologue RhoT induce N-WASP-mediated long process formation and neurite outgrowth. J Cell Sci (2003) 1.21
The PtdIns(3,4)P(2) phosphatase INPP4A is a suppressor of excitotoxic neuronal death. Nature (2010) 1.21
Phosphoinositides regulate clathrin-dependent endocytosis at the tip of pollen tubes in Arabidopsis and tobacco. Plant Cell (2010) 1.20
Short-term retention of actin filament binding proteins on lamellipodial actin bundles. FEBS Lett (2006) 1.20
Regulation of actin cytoskeleton by mDab1 through N-WASP and ubiquitination of mDab1. Biochem J (2004) 1.20
Regulation of cortical actin networks in cell migration. Int Rev Cytol (2003) 1.18
The WASP and WAVE family proteins. Genome Biol (2009) 1.18
Serum metabolomics as a novel diagnostic approach for gastrointestinal cancer. Biomed Chromatogr (2011) 1.16
Discovery of candidate disease genes in ENU-induced mouse mutants by large-scale sequencing, including a splice-site mutation in nucleoredoxin. PLoS Genet (2009) 1.16
Sufu recruits GSK3beta for efficient processing of Gli3. Biochem Biophys Res Commun (2009) 1.15
SKIP negatively regulates insulin-induced GLUT4 translocation and membrane ruffle formation. Mol Cell Biol (2003) 1.15
Neural Wiskott-Aldrich syndrome protein (N-WASP) is the specific ligand for Shigella VirG among the WASP family and determines the host cell type allowing actin-based spreading. Cell Microbiol (2002) 1.15
Mycotoxins in rice. Int J Food Microbiol (2007) 1.13
SGIP1alpha is an endocytic protein that directly interacts with phospholipids and Eps15. J Biol Chem (2007) 1.11
Successful percutaneous transluminal angioplasty and stenting for symptomatic intracranial vertebral artery stenosis using intravascular ultrasound virtual histology. Radiat Med (2007) 1.11
Kif26b, a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme. Proc Natl Acad Sci U S A (2010) 1.09
Cerebellar hemorrhage after spine surgery. J Orthop Sci (2008) 1.09
WAVE/Scars in platelets. Blood (2004) 1.09
Nucleoredoxin, a novel thioredoxin family member involved in cell growth and differentiation. Antioxid Redox Signal (2007) 1.09
Visualization and force measurement of branching by Arp2/3 complex and N-WASP in actin filament. Biochem Biophys Res Commun (2002) 1.08
Neural Wiskott-Aldrich syndrome protein is recruited to rafts and associates with endophilin A in response to epidermal growth factor. J Biol Chem (2002) 1.08
DA-Raf1, a competent intrinsic dominant-negative antagonist of the Ras-ERK pathway, is required for myogenic differentiation. J Cell Biol (2007) 1.06
WASP-related proteins, Abi1 and Ena/VASP are required for Listeria invasion induced by the Met receptor. J Cell Sci (2005) 1.05
Phospholipase Cdelta4 is required for Ca2+ mobilization essential for acrosome reaction in sperm. J Cell Biol (2003) 1.05
Usefulness of white blood cell differential for early diagnosis of surgical wound infection following spinal instrumentation surgery. Spine (Phila Pa 1976) (2006) 1.05
Effect of WAVE2 phosphorylation on activation of the Arp2/3 complex. J Biochem (2007) 1.05
N-WASP and WAVE2 acting downstream of phosphatidylinositol 3-kinase are required for myogenic cell migration induced by hepatocyte growth factor. J Biol Chem (2004) 1.04
Pseudoarthrosis of vertebral fracture: radiographic and characteristic clinical features and natural history. J Orthop Sci (2006) 1.04
Translocation of N-WASP by nuclear localization and export signals into the nucleus modulates expression of HSP90. J Biol Chem (2003) 1.04
Nucleoredoxin sustains Wnt/β-catenin signaling by retaining a pool of inactive dishevelled protein. Curr Biol (2010) 1.04
WASP and WAVE family proteins: friends or foes in cancer invasion? Cancer Sci (2010) 1.03
Crystal structure of human DAAM1 formin homology 2 domain. Genes Cells (2007) 1.02
Phospholipase Cdelta1 is required for skin stem cell lineage commitment. EMBO J (2003) 1.02
Polarity-regulating kinase partitioning-defective 1/microtubule affinity-regulating kinase 2 negatively regulates development of dendrites on hippocampal neurons. J Neurosci (2007) 1.01
A unique gene expression signature discriminates familial Alzheimer's disease mutation carriers from their wild-type siblings. Proc Natl Acad Sci U S A (2005) 1.01
PtdIns(3,4)P2 instigates focal adhesions to generate podosomes. Cell Adh Migr (2009) 1.00
SH3YL1 regulates dorsal ruffle formation by a novel phosphoinositide-binding domain. J Cell Biol (2011) 1.00
WAVE2 serves a functional partner of IRSp53 by regulating its interaction with Rac. Biochem Biophys Res Commun (2002) 1.00
Spatial and temporal regulation of actin polymerization for cytoskeleton formation through Arp2/3 complex and WASP/WAVE proteins. Cell Motil Cytoskeleton (2002) 1.00
WICH, a novel verprolin homology domain-containing protein that functions cooperatively with N-WASP in actin-microspike formation. Biochem Biophys Res Commun (2002) 1.00
Cyclo(L-leucyl-L-prolyl) produced by Achromobacter xylosoxidans inhibits aflatoxin production by Aspergillus parasiticus. Appl Environ Microbiol (2004) 0.99
Transcriptional regulation of fruit ripening by tomato FRUITFULL homologs and associated MADS box proteins. Plant Cell (2014) 0.99
Thioredoxin mediates oxidation-dependent phosphorylation of CRMP2 and growth cone collapse. Sci Signal (2011) 0.99
A novel function of WAVE in lamellipodia: WAVE1 is required for stabilization of lamellipodial protrusions during cell spreading. Genes Cells (2005) 0.99