PubRank

Susan Bonner-Weir

Author PubWeight™ 137.96‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 2003 16.62
2 p16INK4a induces an age-dependent decline in islet regenerative potential. Nature 2006 9.09
3 Five stages of evolving beta-cell dysfunction during progression to diabetes. Diabetes 2004 4.73
4 Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth. Proc Natl Acad Sci U S A 2008 4.01
5 Selective beta-cell loss and alpha-cell expansion in patients with type 2 diabetes mellitus in Korea. J Clin Endocrinol Metab 2003 3.87
6 In vivo imaging of islet transplantation. Nat Med 2005 2.97
7 Residual insulin production and pancreatic ß-cell turnover after 50 years of diabetes: Joslin Medalist Study. Diabetes 2010 2.94
8 A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells. Dev Biol 2006 2.62
9 Downregulation of GLP-1 and GIP receptor expression by hyperglycemia: possible contribution to impaired incretin effects in diabetes. Diabetes 2007 1.99
10 Islet β cell mass in diabetes and how it relates to function, birth, and death. Ann N Y Acad Sci 2013 1.84
11 Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice. Proc Natl Acad Sci U S A 2008 1.83
12 Involvement of c-Jun N-terminal kinase in oxidative stress-mediated suppression of insulin gene expression. J Biol Chem 2002 1.76
13 Suppression of beta cell energy metabolism and insulin release by PGC-1alpha. Dev Cell 2003 1.71
14 Gene expression of purified beta-cell tissue obtained from human pancreas with laser capture microdissection. J Clin Endocrinol Metab 2007 1.68
15 Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes. PLoS One 2010 1.68
16 Tissue-specific disallowance of housekeeping genes: the other face of cell differentiation. Genome Res 2010 1.67
17 Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes. J Biol Chem 2002 1.67
18 In vivo imaging of immune rejection in transplanted pancreatic islets. Diabetes 2006 1.65
19 Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to beta-cell survival during chronic hyperglycemia. Diabetes 2002 1.51
20 Differentiation of affinity-purified human pancreatic duct cells to beta-cells. Diabetes 2007 1.50
21 Overexpression of c-Myc in beta-cells of transgenic mice causes proliferation and apoptosis, downregulation of insulin gene expression, and diabetes. Diabetes 2002 1.43
22 Quantitative analysis of cell composition and purity of human pancreatic islet preparations. Lab Invest 2010 1.43
23 Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia. J Biol Chem 2002 1.41
24 Ductal origin hypothesis of pancreatic regeneration under attack. Cell Metab 2010 1.41
25 Activation of pancreatic-duct-derived progenitor cells during pancreas regeneration in adult rats. J Cell Sci 2010 1.40
26 GLP-1/exendin-4 facilitates beta-cell neogenesis in rat and human pancreatic ducts. Diabetes Res Clin Pract 2006 1.37
27 Modification of adverse inflammation is required to cure new-onset type 1 diabetic hosts. Proc Natl Acad Sci U S A 2007 1.35
28 PDX-1 protein containing its own antennapedia-like protein transduction domain can transduce pancreatic duct and islet cells. Diabetes 2003 1.34
29 In vivo multimodal imaging of transplanted pancreatic islets. Nat Protoc 2006 1.29
30 Overexpression of inducible cyclic AMP early repressor inhibits transactivation of genes and cell proliferation in pancreatic beta cells. Mol Cell Biol 2004 1.28
31 Thyroid hormone promotes postnatal rat pancreatic β-cell development and glucose-responsive insulin secretion through MAFA. Diabetes 2013 1.22
32 A dominant role for glucose in beta cell compensation of insulin resistance. J Clin Invest 2007 1.22
33 Stem cell therapy for type 1 diabetes mellitus. Nat Rev Endocrinol 2010 1.21
34 Toward development of imaging modalities for islets after transplantation: insights from the National Institutes of Health Workshop on Beta Cell Imaging. Transplantation 2004 1.17
35 Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction. Proc Natl Acad Sci U S A 2009 1.17
36 Conversion of mature human β-cells into glucagon-producing α-cells. Diabetes 2013 1.16
37 Mice with a targeted deletion of the type 2 deiodinase are insulin resistant and susceptible to diet induced obesity. PLoS One 2011 1.15
38 Evidence for a role of the ubiquitin-proteasome pathway in pancreatic islets. Diabetes 2006 1.12
39 Protein-tyrosine phosphatase 1B deficiency reduces insulin resistance and the diabetic phenotype in mice with polygenic insulin resistance. J Biol Chem 2007 1.12
40 Adult mouse intrahepatic biliary epithelial cells induced in vitro to become insulin-producing cells. J Endocrinol 2009 1.10
41 Survival and maturation of microencapsulated porcine neonatal pancreatic cell clusters transplanted into immunocompetent diabetic mice. Diabetes 2003 1.10
42 Metabolic decompensation in pump users due to lispro insulin precipitation. BMJ 2002 1.07
43 Preferential reduction of beta cells derived from Pax6-MafB pathway in MafB deficient mice. Dev Biol 2007 1.07
44 Induction of pancreatic stem/progenitor cells into insulin-producing cells by adenoviral-mediated gene transfer technology. Cell Transplant 2006 1.06
45 BETA2/NeuroD protein can be transduced into cells due to an arginine- and lysine-rich sequence. Diabetes 2005 1.05
46 Imaging beta-cell death with a near-infrared probe. Diabetes 2005 1.03
47 Stem cell approaches for diabetes: towards beta cell replacement. Genome Med 2011 1.02
48 Laser capture microdissection of human pancreatic beta-cells and RNA preparation for gene expression profiling. Methods Mol Biol 2009 1.00
49 Timing and expression pattern of carbonic anhydrase II in pancreas. Dev Dyn 2006 1.00
50 Identification of markers for newly formed beta-cells in the perinatal period: a time of recognized beta-cell immaturity. J Histochem Cytochem 2010 0.99
51 Involvement of protein kinase C beta 2 in c-myc induction by high glucose in pancreatic beta-cells. J Biol Chem 2001 0.98
52 p38 MAPK is a major regulator of MafA protein stability under oxidative stress. Mol Endocrinol 2009 0.98
53 Concise review: pancreas regeneration: recent advances and perspectives. Stem Cells Transl Med 2012 0.98
54 Regenerating pancreatic beta-cells: plasticity of adult pancreatic cells and the feasibility of in-vivo neogenesis. Curr Opin Organ Transplant 2010 0.95
55 Porcine marginal mass islet autografts resist metabolic failure over time and are enhanced by early treatment with liraglutide. Endocrinology 2009 0.95
56 Induction of c-Myc expression suppresses insulin gene transcription by inhibiting NeuroD/BETA2-mediated transcriptional activation. J Biol Chem 2002 0.95
57 Preservation of beta-cell function by targeting beta-cell mass. Trends Pharmacol Sci 2008 0.94
58 Photo-acceleration of protein release from endosome in the protein transduction system. FEBS Lett 2004 0.94
59 Loss of Ncb5or results in impaired fatty acid desaturation, lipoatrophy, and diabetes. J Biol Chem 2008 0.92
60 Birth and death of human β-cells in pancreases from cadaver donors, autopsies, surgical specimens, and islets transplanted into mice. Cell Transplant 2013 0.92
61 Normal relationship of beta- and non-beta-cells not needed for successful islet transplantation. Diabetes 2007 0.91
62 Expression of MafA in pancreatic progenitors is detrimental for pancreatic development. Dev Biol 2009 0.91
63 Protective unfolded protein response in human pancreatic beta cells transplanted into mice. PLoS One 2010 0.90
64 Quantitative assessment of islets of Langerhans encapsulated in alginate. Tissue Eng Part C Methods 2011 0.89
65 Establishment of a diabetic mouse model with progressive diabetic nephropathy. Am J Pathol 2005 0.89
66 Mechanism of PDX-1 protein transduction. Biochem Biophys Res Commun 2005 0.89
67 Pancreatic duct ligation after almost complete β-cell loss: exocrine regeneration but no evidence of β-cell regeneration. Endocrinology 2013 0.88
68 Subpopulations of GFP-marked mouse pancreatic β-cells differ in size, granularity, and insulin secretion. Endocrinology 2012 0.88
69 Developmental pathways during in vitro progression of human islet neogenesis. Differentiation 2008 0.87
70 PDX1 in ducts is not required for postnatal formation of β-cells but is necessary for their subsequent maturation. Diabetes 2013 0.87
71 NeuroD and reaggregation induce beta-cell specific gene expression in cultured hepatocytes. Diabetes Metab Res Rev 2007 0.86
72 Transplantation of islets transduced with CTLA4-Ig and TGFbeta using adenovirus and lentivirus vectors. Transpl Immunol 2004 0.86
73 Importance of hyperglycemia on the primary function of allogeneic islet transplants. Transplantation 2003 0.85
74 TNF-like weak inducer of apoptosis (TWEAK) promotes beta cell neogenesis from pancreatic ductal epithelium in adult mice. PLoS One 2013 0.85
75 Macrophage depletion improves survival of porcine neonatal pancreatic cell clusters contained in alginate macrocapsules transplanted into rats. Xenotransplantation 2003 0.85
76 Induced ICER Igamma down-regulates cyclin A expression and cell proliferation in insulin-producing beta cells. Biochem Biophys Res Commun 2005 0.84
77 Accurate control of oxygen level in cells during culture on silicone rubber membranes with application to stem cell differentiation. Biotechnol Prog 2010 0.84
78 Beta-cell precursors--a work in progress. Nat Biotechnol 2004 0.83
79 Reprogramming Mouse Cells With a Pancreatic Duct Phenotype to Insulin-Producing β-Like Cells. Endocrinology 2015 0.81
80 Making β cells from adult cells within the pancreas. Curr Diab Rep 2013 0.81
81 Occurrence of spontaneous pancreatic lesions in normal and diabetic rats: a potential confounding factor in the nonclinical assessment of GLP-1-based therapies. Diabetes 2013 0.81
82 Sleeping islets and the relationship between β-cell mass and function. Diabetes 2011 0.81
83 Enumeration of islets by nuclei counting and light microscopic analysis. Lab Invest 2010 0.81
84 Bone marrow or foetal liver cells fail to induce islet regeneration in diabetic Akita mice. Diabetes Metab Res Rev 2008 0.79
85 β-Cell differentiation of human pancreatic duct-derived cells after in vitro expansion. Cell Reprogram 2014 0.79
86 Finally! A human pancreatic β cell line. J Clin Invest 2011 0.79
87 Development and retroviral transduction of porcine neonatal pancreatic islet cells in monolayer culture. Dev Growth Differ 2003 0.78
88 Lack of evidence for recipient precursor cells replenishing β-cells in transplanted islets. Cell Transplant 2010 0.78
89 Physiology: Pancreatic β-cell heterogeneity revisited. Nature 2016 0.77
90 How can we get more beta cells? Curr Diab Rep 2006 0.77
91 New clues to bariatric surgery's benefits. Nat Med 2012 0.77
92 Sustained NF-κB activation and inhibition in β-cells have minimal effects on function and islet transplant outcomes. PLoS One 2013 0.76
93 Dreams for type 1 diabetes: shutting off autoimmunity and stimulating beta-cell regeneration. Endocrinology 2010 0.76