Published in Diabetes on January 01, 2003
Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice. Nat Med (2016) 2.15
Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates. Nat Biotechnol (2016) 2.04
Update on islet transplantation. Cold Spring Harb Perspect Med (2012) 1.40
Challenges and emerging technologies in the immunoisolation of cells and tissues. Adv Drug Deliv Rev (2007) 1.24
Trimodal gadolinium-gold microcapsules containing pancreatic islet cells restore normoglycemia in diabetic mice and can be tracked by using US, CT, and positive-contrast MR imaging. Radiology (2011) 1.19
Islets transplanted in immunoisolation devices: a review of the progress and the challenges that remain. Endocr Rev (2011) 1.10
Islet transplantation and encapsulation: an update on recent developments. Rev Diabet Stud (2011) 0.98
Macro- or microencapsulation of pig islets to cure type 1 diabetes. World J Gastroenterol (2012) 0.91
Survival of human islets in microbeads containing high guluronic acid alginate crosslinked with Ca2+ and Ba2+. Xenotransplantation (2012) 0.82
Biocompatibility and immune acceptance of adult porcine islets transplanted intraperitoneally in diabetic NOD mice in calcium alginate poly-L-lysine microcapsules versus barium alginate microcapsules without poly-L-lysine. J Diabetes Sci Technol (2008) 0.81
Characterisation of the xenogeneic immune response to microencapsulated fetal pig islet-like cell clusters transplanted into immunocompetent C57BL/6 mice. PLoS One (2013) 0.79
Long-term graft function of cryostored alginate encapsulated rat islets. Eur J Med Res (2011) 0.79
Microencapsulation for the Therapeutic Delivery of Drugs, Live Mammalian and Bacterial Cells, and Other Biopharmaceutics: Current Status and Future Directions. J Pharm (Cairo) (2012) 0.78
Prospects and challenges for islet regeneration as a treatment for diabetes: a review of islet neogenesis associated protein. J Diabetes Sci Technol (2007) 0.78
Treatment of diabetes with encapsulated pig islets: an update on current developments. J Zhejiang Univ Sci B (2015) 0.75
Preparation and in vitro studies of microencapsulated cells releasing human tissue inhibitor of metalloproteinase-2. J Zhejiang Univ Sci B (2005) 0.75
Repeated gene transfection impairs the engraftment of transplanted porcine neonatal pancreatic cells. Diabetes Metab J (2011) 0.75
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes (2003) 16.62
p16INK4a induces an age-dependent decline in islet regenerative potential. Nature (2006) 9.09
Five stages of evolving beta-cell dysfunction during progression to diabetes. Diabetes (2004) 4.73
Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth. Proc Natl Acad Sci U S A (2008) 4.01
Selective beta-cell loss and alpha-cell expansion in patients with type 2 diabetes mellitus in Korea. J Clin Endocrinol Metab (2003) 3.87
New sources of pancreatic beta-cells. Nat Biotechnol (2005) 3.11
In vivo imaging of islet transplantation. Nat Med (2005) 2.97
Residual insulin production and pancreatic ß-cell turnover after 50 years of diabetes: Joslin Medalist Study. Diabetes (2010) 2.94
A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells. Dev Biol (2006) 2.62
Downregulation of GLP-1 and GIP receptor expression by hyperglycemia: possible contribution to impaired incretin effects in diabetes. Diabetes (2007) 1.99
Beta-cell growth and regeneration: replication is only part of the story. Diabetes (2010) 1.92
Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation. J Clin Endocrinol Metab (2008) 1.91
The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells. Proc Natl Acad Sci U S A (2005) 1.88
Islet β cell mass in diabetes and how it relates to function, birth, and death. Ann N Y Acad Sci (2013) 1.84
Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice. Proc Natl Acad Sci U S A (2008) 1.83
Involvement of c-Jun N-terminal kinase in oxidative stress-mediated suppression of insulin gene expression. J Biol Chem (2002) 1.76
A stirred microchamber for oxygen consumption rate measurements with pancreatic islets. Biotechnol Bioeng (2007) 1.73
The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation. Cell Metab (2005) 1.72
Suppression of beta cell energy metabolism and insulin release by PGC-1alpha. Dev Cell (2003) 1.71
Gene expression of purified beta-cell tissue obtained from human pancreas with laser capture microdissection. J Clin Endocrinol Metab (2007) 1.68
Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes. PLoS One (2010) 1.68
Tissue-specific disallowance of housekeeping genes: the other face of cell differentiation. Genome Res (2010) 1.67
Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes. J Biol Chem (2002) 1.67
Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes. J Biol Chem (2005) 1.65
In vivo imaging of immune rejection in transplanted pancreatic islets. Diabetes (2006) 1.65
Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to beta-cell survival during chronic hyperglycemia. Diabetes (2002) 1.51
Differentiation of affinity-purified human pancreatic duct cells to beta-cells. Diabetes (2007) 1.50
Overexpression of c-Myc in beta-cells of transgenic mice causes proliferation and apoptosis, downregulation of insulin gene expression, and diabetes. Diabetes (2002) 1.43
Quantitative analysis of cell composition and purity of human pancreatic islet preparations. Lab Invest (2010) 1.43
Current status of islet cell replacement and regeneration therapy. J Clin Endocrinol Metab (2010) 1.43
Ductal origin hypothesis of pancreatic regeneration under attack. Cell Metab (2010) 1.41
Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia. J Biol Chem (2002) 1.41
Activation of pancreatic-duct-derived progenitor cells during pancreas regeneration in adult rats. J Cell Sci (2010) 1.40
GLP-1/exendin-4 facilitates beta-cell neogenesis in rat and human pancreatic ducts. Diabetes Res Clin Pract (2006) 1.37
Modification of adverse inflammation is required to cure new-onset type 1 diabetic hosts. Proc Natl Acad Sci U S A (2007) 1.35
PDX-1 protein containing its own antennapedia-like protein transduction domain can transduce pancreatic duct and islet cells. Diabetes (2003) 1.34
In vivo multimodal imaging of transplanted pancreatic islets. Nat Protoc (2006) 1.29
Overexpression of inducible cyclic AMP early repressor inhibits transactivation of genes and cell proliferation in pancreatic beta cells. Mol Cell Biol (2004) 1.28
Prediction of marginal mass required for successful islet transplantation. J Invest Surg (2010) 1.23
Thyroid hormone promotes postnatal rat pancreatic β-cell development and glucose-responsive insulin secretion through MAFA. Diabetes (2013) 1.22
A dominant role for glucose in beta cell compensation of insulin resistance. J Clin Invest (2007) 1.22
Stem cell therapy for type 1 diabetes mellitus. Nat Rev Endocrinol (2010) 1.21
Retracted Wolfram syndrome 1 and adenylyl cyclase 8 interact at the plasma membrane to regulate insulin production and secretion. Nat Cell Biol (2012) 1.20
Toward development of imaging modalities for islets after transplantation: insights from the National Institutes of Health Workshop on Beta Cell Imaging. Transplantation (2004) 1.17
Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction. Proc Natl Acad Sci U S A (2009) 1.17
Conversion of mature human β-cells into glucagon-producing α-cells. Diabetes (2013) 1.16
Mice with a targeted deletion of the type 2 deiodinase are insulin resistant and susceptible to diet induced obesity. PLoS One (2011) 1.15
Improvement of islet function in a bioartificial pancreas by enhanced oxygen supply and growth hormone releasing hormone agonist. Proc Natl Acad Sci U S A (2012) 1.14
Protein-tyrosine phosphatase 1B deficiency reduces insulin resistance and the diabetic phenotype in mice with polygenic insulin resistance. J Biol Chem (2007) 1.12
Evidence for a role of the ubiquitin-proteasome pathway in pancreatic islets. Diabetes (2006) 1.12
Adult mouse intrahepatic biliary epithelial cells induced in vitro to become insulin-producing cells. J Endocrinol (2009) 1.10
Islets transplanted in immunoisolation devices: a review of the progress and the challenges that remain. Endocr Rev (2011) 1.10
Metabolic decompensation in pump users due to lispro insulin precipitation. BMJ (2002) 1.07
Preferential reduction of beta cells derived from Pax6-MafB pathway in MafB deficient mice. Dev Biol (2007) 1.07
Induction of pancreatic stem/progenitor cells into insulin-producing cells by adenoviral-mediated gene transfer technology. Cell Transplant (2006) 1.06
BETA2/NeuroD protein can be transduced into cells due to an arginine- and lysine-rich sequence. Diabetes (2005) 1.05
Pig islet xenograft rejection in a mouse model with an established human immune system. Xenotransplantation (2008) 1.04
Imaging beta-cell death with a near-infrared probe. Diabetes (2005) 1.03
Enhanced oxygen supply improves islet viability in a new bioartificial pancreas. Cell Transplant (2012) 1.03
Long-term normoglycemia in rats receiving transplants with encapsulated islets. Transplantation (2005) 1.02
Stem cell approaches for diabetes: towards beta cell replacement. Genome Med (2011) 1.02
Changes in diabetes-related complications in the United States. N Engl J Med (2014) 1.01
Laser capture microdissection of human pancreatic beta-cells and RNA preparation for gene expression profiling. Methods Mol Biol (2009) 1.00
Timing and expression pattern of carbonic anhydrase II in pancreas. Dev Dyn (2006) 1.00
Identification of markers for newly formed beta-cells in the perinatal period: a time of recognized beta-cell immaturity. J Histochem Cytochem (2010) 0.99
Effects of insulin replacements, inhibitors of angiotensin, and PKCbeta's actions to normalize cardiac gene expression and fuel metabolism in diabetic rats. Diabetes (2007) 0.98
Involvement of protein kinase C beta 2 in c-myc induction by high glucose in pancreatic beta-cells. J Biol Chem (2001) 0.98
p38 MAPK is a major regulator of MafA protein stability under oxidative stress. Mol Endocrinol (2009) 0.98
Concise review: pancreas regeneration: recent advances and perspectives. Stem Cells Transl Med (2012) 0.98
Regenerating pancreatic beta-cells: plasticity of adult pancreatic cells and the feasibility of in-vivo neogenesis. Curr Opin Organ Transplant (2010) 0.95
Induction of c-Myc expression suppresses insulin gene transcription by inhibiting NeuroD/BETA2-mediated transcriptional activation. J Biol Chem (2002) 0.95
Porcine marginal mass islet autografts resist metabolic failure over time and are enhanced by early treatment with liraglutide. Endocrinology (2009) 0.95
Core-shell hydrogel microcapsules for improved islets encapsulation. Adv Healthc Mater (2012) 0.95
Enhanced function of immuno-isolated islets in diabetes therapy by co-encapsulation with an anti-inflammatory drug. Biomaterials (2013) 0.94
Preservation of beta-cell function by targeting beta-cell mass. Trends Pharmacol Sci (2008) 0.94
Photo-acceleration of protein release from endosome in the protein transduction system. FEBS Lett (2004) 0.94
Loss of Ncb5or results in impaired fatty acid desaturation, lipoatrophy, and diabetes. J Biol Chem (2008) 0.92