Published in Nucleic Acids Res on January 15, 2003
Searching for IRES. RNA (2006) 2.78
A second look at cellular mRNA sequences said to function as internal ribosome entry sites. Nucleic Acids Res (2005) 1.93
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Identification of a motif that mediates polypyrimidine tract-binding protein-dependent internal ribosome entry. Genes Dev (2005) 1.53
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A polypyrimidine tract binding protein, pumpkin RBP50, forms the basis of a phloem-mobile ribonucleoprotein complex. Plant Cell (2009) 1.29
A search for structurally similar cellular internal ribosome entry sites. Nucleic Acids Res (2007) 1.29
The polypyrimidine tract-binding protein stimulates HIF-1alpha IRES-mediated translation during hypoxia. Nucleic Acids Res (2005) 1.25
The hnRNA-binding proteins hnRNP L and PTB are required for efficient translation of the Cat-1 arginine/lysine transporter mRNA during amino acid starvation. Mol Cell Biol (2009) 1.17
Dengue virus utilizes a novel strategy for translation initiation when cap-dependent translation is inhibited. J Virol (2006) 1.17
Alphavirus replicon approach to promoterless analysis of IRES elements. Virology (2006) 1.15
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Polypyrimidine tract-binding protein (PTB) differentially affects malignancy in a cell line-dependent manner. J Biol Chem (2008) 1.07
RNA helicase A interacts with divergent lymphotropic retroviruses and promotes translation of human T-cell leukemia virus type 1. Nucleic Acids Res (2007) 1.06
The polypyrimidine tract binding protein is a monomer. RNA (2005) 1.05
L-Myc protein synthesis is initiated by internal ribosome entry. RNA (2004) 1.03
Regulation of BAG-1 IRES-mediated translation following chemotoxic stress. Oncogene (2007) 1.01
Components of U3 snoRNA-containing complexes shuttle between nuclei and the cytoplasm and differentially localize in nucleoli: implications for assembly and function. Mol Biol Cell (2003) 0.99
Retrovirus translation initiation: Issues and hypotheses derived from study of HIV-1. Curr HIV Res (2006) 0.95
The hnRNP family: insights into their role in health and disease. Hum Genet (2016) 0.94
Remodelling of a polypyrimidine tract-binding protein complex during apoptosis activates cellular IRESs. Cell Death Differ (2013) 0.85
Multiple, but concerted cellular activities of the human protein Hap46/BAG-1M and isoforms. Int J Mol Sci (2009) 0.82
Incrimination of heterogeneous nuclear ribonucleoprotein E1 (hnRNP-E1) as a candidate sensor of physiological folate deficiency. J Biol Chem (2011) 0.82
The 5' leader of the mRNA encoding the mouse neurotrophin receptor TrkB contains two internal ribosomal entry sites that are differentially regulated. PLoS One (2007) 0.81
The Polycomb protein and E3 ubiquitin ligase Ring1B harbors an IRES in its highly conserved 5' UTR. PLoS One (2008) 0.79
Characterization of the internal IRES element of the zebrafish connexin55.5 reveals functional implication of the polypyrimidine tract binding protein. BMC Mol Biol (2008) 0.79
Promoter-Dependent Translation Controlled by p54nrb and hnRNPM during Myoblast Differentiation. PLoS One (2015) 0.78
Activities of the cochaperones Hap46/BAG-1M and Hap50/BAG-1L and isoforms. Cell Stress Chaperones (2006) 0.76
Evidence Favoring a Positive Feedback Loop for Physiologic Auto Upregulation of hnRNP-E1 during Prolonged Folate Deficiency in Human Placental Cells. J Nutr (2017) 0.75
The perinucleolar compartment associates with malignancy. Front Biol (Beijing) (2013) 0.75
Polypyrimidine tract-binding protein (PTB) and PTB-associated splicing factor in CVB3 infection: an ITAF for an ITAF. Nucleic Acids Res (2017) 0.75
Internal ribosome entry sites in eukaryotic mRNA molecules. Genes Dev (2001) 7.60
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Functional dissection of eukaryotic initiation factor 4F: the 4A subunit and the central domain of the 4G subunit are sufficient to mediate internal entry of 43S preinitiation complexes. Mol Cell Biol (1996) 4.42
The poly(C)-binding proteins: a multiplicity of functions and a search for mechanisms. RNA (2002) 3.62
Two functional complexes formed by KH domain containing proteins with the 5' noncoding region of poliovirus RNA. RNA (1997) 3.61
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Multiple RRMs contribute to RNA binding specificity and affinity for polypyrimidine tract binding protein. Biochemistry (1997) 2.35
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Analysis of the c-myc IRES; a potential role for cell-type specific trans-acting factors and the nuclear compartment. Nucleic Acids Res (2000) 2.22
Functional characterization of the X-linked inhibitor of apoptosis (XIAP) internal ribosome entry site element: role of La autoantigen in XIAP translation. Mol Cell Biol (2000) 2.22
Initiation of Apaf-1 translation by internal ribosome entry. Oncogene (2000) 2.01
Differential utilization of poly(rC) binding protein 2 in translation directed by picornavirus IRES elements. RNA (1999) 2.00
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Protein factor requirements of the Apaf-1 internal ribosome entry segment: roles of polypyrimidine tract binding protein and upstream of N-ras. Mol Cell Biol (2001) 1.73
A novel form of DAP5 protein accumulates in apoptotic cells as a result of caspase cleavage and internal ribosome entry site-mediated translation. Mol Cell Biol (2000) 1.72
Poly(rC) binding proteins mediate poliovirus mRNA stability. RNA (2001) 1.63
Expression and location of Hsp70/Hsc-binding anti-apoptotic protein BAG-1 and its variants in normal tissues and tumor cell lines. Cancer Res (1998) 1.57
c-myc Internal ribosome entry site activity is developmentally controlled and subjected to a strong translational repression in adult transgenic mice. Mol Cell Biol (2001) 1.53
Bag-1M accelerates nucleotide release for human Hsc70 and Hsp70 and can act concentration-dependent as positive and negative cofactor. J Biol Chem (2001) 1.52
A protein that interacts with members of the nuclear hormone receptor family: identification and cDNA cloning. Proc Natl Acad Sci U S A (1995) 1.50
Mammalian cells express two differently localized Bag-1 isoforms generated by alternative translation initiation. Biochem J (1997) 1.49
The p36 isoform of BAG-1 is translated by internal ribosome entry following heat shock. Oncogene (2001) 1.44
Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53. EMBO J (2001) 1.42
Modulation of in vivo HSP70 chaperone activity by Hip and Bag-1. J Biol Chem (2000) 1.42
The caspase-cleaved DAP5 protein supports internal ribosome entry site-mediated translation of death proteins. Proc Natl Acad Sci U S A (2002) 1.36
Polypyrimidine tract-binding protein inhibits translation of bip mRNA. J Mol Biol (2000) 1.31
Characterization of interactions between the anti-apoptotic protein BAG-1 and Hsc70 molecular chaperones. J Biol Chem (1998) 1.23
Human BAG-1/RAP46 protein is generated as four isoforms by alternative translation initiation and overexpressed in cancer cells. Oncogene (1998) 1.19
N-myc translation is initiated via an internal ribosome entry segment that displays enhanced activity in neuronal cells. Oncogene (2001) 1.17
The hsp70-associating protein Hap46 binds to DNA and stimulates transcription. Proc Natl Acad Sci U S A (1999) 1.09
Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice. Sci Transl Med (2013) 4.62
Sustained translational repression by eIF2α-P mediates prion neurodegeneration. Nature (2012) 3.54
Translational regulation of gene expression during conditions of cell stress. Mol Cell (2010) 3.38
Cellular internal ribosome entry segments: structures, trans-acting factors and regulation of gene expression. Oncogene (2004) 2.78
The implications of structured 5' untranslated regions on translation and disease. Semin Cell Dev Biol (2004) 2.78
The Apaf-1 internal ribosome entry segment attains the correct structural conformation for function via interactions with PTB and unr. Mol Cell (2003) 2.28
Re-programming of translation following cell stress allows IRES-mediated translation to predominate. Biol Cell (2008) 2.17
Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein. Biochem Soc Trans (2008) 2.12
The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene. Proc Natl Acad Sci U S A (2008) 2.09
Members of the poly (rC) binding protein family stimulate the activity of the c-myc internal ribosome entry segment in vitro and in vivo. Oncogene (2003) 1.83
p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication. Proc Natl Acad Sci U S A (2010) 1.77
Polypyrimidine tract binding protein regulates IRES-mediated gene expression during apoptosis. Mol Cell (2006) 1.71
A perspective on mammalian upstream open reading frame function. Int J Biochem Cell Biol (2013) 1.59
Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes. Genes Dev (2009) 1.56
A MAPK/HNRPK pathway controls BCR/ABL oncogenic potential by regulating MYC mRNA translation. Blood (2005) 1.56
The biological and therapeutic relevance of mRNA translation in cancer. Nat Rev Clin Oncol (2011) 1.54
Identification of a motif that mediates polypyrimidine tract-binding protein-dependent internal ribosome entry. Genes Dev (2005) 1.53
A novel method for poly(A) fractionation reveals a large population of mRNAs with a short poly(A) tail in mammalian cells. Nucleic Acids Res (2007) 1.45
Identification of internal ribosome entry segment (IRES)-trans-acting factors for the Myc family of IRESs. Mol Cell Biol (2007) 1.44
Bag-1 internal ribosome entry segment activity is promoted by structural changes mediated by poly(rC) binding protein 1 and recruitment of polypyrimidine tract binding protein 1. Mol Cell Biol (2004) 1.38
Canonical initiation factor requirements of the Myc family of internal ribosome entry segments. Mol Cell Biol (2009) 1.21
Dysregulation of protein synthesis and disease. J Pathol (2010) 1.21
The involvement of microRNAs in Type 2 diabetes. Biochem Soc Trans (2010) 1.17
The RNA binding protein Larp1 regulates cell division, apoptosis and cell migration. Nucleic Acids Res (2010) 1.17
CTCF mediates insulator function at the CFTR locus. Biochem J (2007) 1.16
The role of IRES trans-acting factors in regulating translation initiation. Biochem Soc Trans (2010) 1.15
L-Myc protein synthesis is initiated by internal ribosome entry. RNA (2004) 1.03
Ribosomal protein S25 dependency reveals a common mechanism for diverse internal ribosome entry sites and ribosome shunting. Mol Cell Biol (2012) 0.99
The human insulin receptor mRNA contains a functional internal ribosome entry segment. Nucleic Acids Res (2009) 0.96
Failure of translation of human adenovirus mRNA in murine cancer cells can be partially overcome by L4-100K expression in vitro and in vivo. Mol Ther (2012) 0.90
Low proliferative and high migratory activity in the area of Brachyury expressing mesoderm progenitor cells in the gastrulating rabbit embryo. Development (2002) 0.90
Aberrant regulation of translation initiation in tumorigenesis. Curr Mol Med (2003) 0.90
Viral strategies to subvert the mammalian translation machinery. Prog Mol Biol Transl Sci (2009) 0.89
ATR (ataxia telangiectasia mutated- and Rad3-related kinase) is activated by mild hypothermia in mammalian cells and subsequently activates p53. Biochem J (2011) 0.88
Generation of DeltaTAp73 proteins by translation from a putative internal ribosome entry site. Ann N Y Acad Sci (2007) 0.86
Rapamycin regulates biochemical metabolites. Cell Cycle (2013) 0.84
Evaluating bias-reducing protocols for RNA sequencing library preparation. BMC Genomics (2014) 0.83
eIF4A inhibition allows translational regulation of mRNAs encoding proteins involved in Alzheimer's disease. PLoS One (2010) 0.83
Metabolic profiling of human CD4+ cells following treatment with methotrexate and anti-TNF-α infliximab. Cell Cycle (2013) 0.83
Active regulator of SIRT1 is required for ribosome biogenesis and function. Nucleic Acids Res (2013) 0.82
Large scale integration of drug-target information reveals poly-pharmacological drug action mechanisms in tumor cell line growth inhibition assays. Oncotarget (2014) 0.79
Translation deregulation in B-cell lymphomas. Biochem Soc Trans (2010) 0.78
SF2/ASF TORCs up translation. Mol Cell (2008) 0.77
An integrative biological approach to the analysis of tissue culture data: application to the antitumour agent RHPS4. Integr Biol (Camb) (2011) 0.76
Co-ordinated regulation of translation following DNA damage. Cell Cycle (2009) 0.75