Published in J Neurosci on February 01, 2003
Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward. Science (2010) 5.48
Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nat Neurosci (2010) 3.41
Decoding the epigenetic language of neuronal plasticity. Neuron (2008) 3.23
MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212. Nat Neurosci (2010) 3.00
Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins. Neuron (2009) 2.97
Neuroplasticity in the mesolimbic dopamine system and cocaine addiction. Br J Pharmacol (2008) 2.83
Cocaine but not natural reward self-administration nor passive cocaine infusion produces persistent LTP in the VTA. Neuron (2008) 2.69
Neurobiology of the incubation of drug craving. Trends Neurosci (2011) 2.65
AMPA receptor plasticity in the nucleus accumbens after repeated exposure to cocaine. Neurosci Biobehav Rev (2010) 2.58
Epigenetic mechanisms in cognition. Neuron (2011) 2.31
Nuclear factor kappa B signaling regulates neuronal morphology and cocaine reward. J Neurosci (2009) 2.25
Epigenetic mechanisms in drug addiction. Trends Mol Med (2008) 2.14
The reinstatement model of drug relapse: recent neurobiological findings, emerging research topics, and translational research. Psychopharmacology (Berl) (2013) 2.01
Neurotrophic factors and structural plasticity in addiction. Neuropharmacology (2008) 1.99
Role of ventral medial prefrontal cortex in incubation of cocaine craving. Neuropharmacology (2008) 1.99
A role for repressive histone methylation in cocaine-induced vulnerability to stress. Neuron (2011) 1.92
Elevated BDNF after cocaine withdrawal facilitates LTP in medial prefrontal cortex by suppressing GABA inhibition. Neuron (2010) 1.90
Targeting extinction and reconsolidation mechanisms to combat the impact of drug cues on addiction. Neuropharmacology (2008) 1.84
Brain-derived neurotrophic factor and cocaine addiction. Brain Res (2009) 1.76
Involvement of AMPA/kainate, NMDA, and mGlu5 receptors in the nucleus accumbens core in cue-induced reinstatement of cocaine seeking in rats. Psychopharmacology (Berl) (2007) 1.69
AMPA receptor synaptic plasticity induced by psychostimulants: the past, present, and therapeutic future. Neuron (2010) 1.68
Escalated or suppressed cocaine reward, tegmental BDNF, and accumbal dopamine caused by episodic versus continuous social stress in rats. J Neurosci (2011) 1.62
Endogenous BDNF in the dorsolateral striatum gates alcohol drinking. J Neurosci (2009) 1.62
Increased serum brain-derived neurotrophic factor is predictive of cocaine relapse outcomes: a prospective study. Biol Psychiatry (2011) 1.61
AKT signaling within the ventral tegmental area regulates cellular and behavioral responses to stressful stimuli. Biol Psychiatry (2008) 1.60
Cocaine seeking over extended withdrawal periods in rats: different time courses of responding induced by cocaine cues versus cocaine priming over the first 6 months. Psychopharmacology (Berl) (2004) 1.59
The epigenetic landscape of addiction. Ann N Y Acad Sci (2011) 1.51
Role of accumbens BDNF and TrkB in cocaine-induced psychomotor sensitization, conditioned-place preference, and reinstatement in rats. Psychopharmacology (Berl) (2008) 1.48
Role of ventral tegmental area glial cell line-derived neurotrophic factor in incubation of cocaine craving. Biol Psychiatry (2009) 1.48
Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaine. J Neurosci (2010) 1.47
Chronic cocaine-induced H3 acetylation and transcriptional activation of CaMKIIalpha in the nucleus accumbens is critical for motivation for drug reinforcement. Neuropsychopharmacology (2009) 1.46
Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area. Nat Neurosci (2015) 1.43
Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine. Proc Natl Acad Sci U S A (2007) 1.42
Brain derived neurotrophic factor (BDNF) gene variants and Alzheimer's disease, affective disorders, posttraumatic stress disorder, schizophrenia, and substance dependence. Am J Med Genet B Neuropsychiatr Genet (2006) 1.41
Ventral tegmental area BDNF induces an opiate-dependent-like reward state in naive rats. Science (2009) 1.40
Central amygdala extracellular signal-regulated kinase signaling pathway is critical to incubation of opiate craving. J Neurosci (2008) 1.39
Addiction and brain reward and antireward pathways. Adv Psychosom Med (2011) 1.38
Role of BDNF and GDNF in drug reward and relapse: a review. Neurosci Biobehav Rev (2009) 1.31
Incubation of nicotine seeking is associated with enhanced protein kinase A-regulated signaling of dopamine- and cAMP-regulated phosphoprotein of 32 kDa in the insular cortex. Eur J Neurosci (2010) 1.30
Recent developments in animal models of drug relapse. Curr Opin Neurobiol (2013) 1.30
Short- and long-term effects of intermittent social defeat stress on brain-derived neurotrophic factor expression in mesocorticolimbic brain regions. Neuroscience (2010) 1.27
Loss of object recognition memory produced by extended access to methamphetamine self-administration is reversed by positive allosteric modulation of metabotropic glutamate receptor 5. Neuropsychopharmacology (2010) 1.25
Molecular mechanisms of psychostimulant-induced structural plasticity. Pharmacopsychiatry (2009) 1.25
Histone acetylation in drug addiction. Semin Cell Dev Biol (2009) 1.24
Effects of extended-access self-administration and deprivation on breakpoints maintained by cocaine in rats. Psychopharmacology (Berl) (2005) 1.23
Global and local morphometric differences in recently abstinent methamphetamine-dependent individuals. Neuroimage (2010) 1.23
Nicotinic acetylcholine receptors in the ventral tegmental area mediate the dopamine activating and reinforcing properties of ethanol cues. Psychopharmacology (Berl) (2007) 1.22
Attenuation of cocaine-seeking by progesterone treatment in female rats. Psychoneuroendocrinology (2008) 1.21
Aberrant learning and memory in addiction. Neurobiol Learn Mem (2011) 1.19
The role of histone acetylation in cocaine-induced neural plasticity and behavior. Neuropsychopharmacology (2012) 1.19
Individual differences and social influences on the neurobehavioral pharmacology of abused drugs. Pharmacol Rev (2013) 1.16
Endocrine and gene expression changes following forced swim stress exposure during cocaine abstinence in mice. Psychopharmacology (Berl) (2008) 1.14
Neurobiology of dysregulated motivational systems in drug addiction. Future Neurol (2010) 1.14
Escalating ethanol intake is associated with altered corticostriatal BDNF expression. J Neurochem (2009) 1.13
Making a bad thing worse: adverse effects of stress on drug addiction. J Clin Invest (2008) 1.13
Forced abstinence model of relapse to study pharmacological treatments of substance use disorder. Curr Drug Abuse Rev (2009) 1.11
Molecular and genetic substrates linking stress and addiction. Brain Res (2009) 1.11
microRNA-206 in rat medial prefrontal cortex regulates BDNF expression and alcohol drinking. J Neurosci (2014) 1.11
The neural rejuvenation hypothesis of cocaine addiction. Trends Pharmacol Sci (2014) 1.10
CREB phosphorylation regulates striatal transcriptional responses in the self-administration model of methamphetamine addiction in the rat. Neurobiol Dis (2013) 1.10
Exercise as a novel treatment for drug addiction: a neurobiological and stage-dependent hypothesis. Neurosci Biobehav Rev (2013) 1.10
Relapse to drug seeking following prolonged abstinence: the role of environmental stimuli. Drug Discov Today Dis Models (2008) 1.10
Adaptations in AMPA receptor transmission in the nucleus accumbens contributing to incubation of cocaine craving. Neuropharmacology (2013) 1.10
Review. Psychological and neural mechanisms of relapse. Philos Trans R Soc Lond B Biol Sci (2008) 1.09
Association of the met66 allele of brain-derived neurotrophic factor (BDNF) with smoking. Psychopharmacology (Berl) (2006) 1.09
Understanding the neurobiological consequences of early exposure to psychotropic drugs: linking behavior with molecules. Neuropharmacology (2004) 1.09
Neurochemistry of the nucleus accumbens and its relevance to depression and antidepressant action in rodents. Curr Neuropharmacol (2006) 1.07
The contribution of drug history and time since termination of drug taking to footshock stress-induced cocaine seeking in rats. Psychopharmacology (Berl) (2005) 1.07
Liking and wanting of drug and non-drug rewards in active cocaine users: the STRAP-R questionnaire. J Psychopharmacol (2008) 1.07
Heroin self-administration: II. CNS gene expression following withdrawal and cue-induced drug-seeking behavior. Pharmacol Biochem Behav (2008) 1.07
Upregulation of Arc mRNA expression in the prefrontal cortex following cue-induced reinstatement of extinguished cocaine-seeking behavior. Synapse (2008) 1.05
Protein kinases and addiction. Ann N Y Acad Sci (2008) 1.05
Synaptic mechanisms underlying persistent cocaine craving. Nat Rev Neurosci (2016) 1.03
Increased brain-derived neurotrophic factor (BDNF) expression in the ventral tegmental area during cocaine abstinence is associated with increased histone acetylation at BDNF exon I-containing promoters. J Neurochem (2011) 1.02
TrkB signaling is required for behavioral sensitization and conditioned place preference induced by a single injection of cocaine. Neuropharmacology (2010) 1.01
Molecular, cellular, and structural mechanisms of cocaine addiction: a key role for microRNAs. Neuropsychopharmacology (2012) 1.01
Endogenous GDNF in ventral tegmental area and nucleus accumbens does not play a role in the incubation of heroin craving. Addict Biol (2010) 1.00
A role for BDNF in cocaine reward and relapse. Nat Neurosci (2007) 0.99
Brain-derived neurotrophic factor rapidly increases AMPA receptor surface expression in rat nucleus accumbens. Eur J Neurosci (2011) 0.98
Different roles of BDNF in nucleus accumbens core versus shell during the incubation of cue-induced cocaine craving and its long-term maintenance. J Neurosci (2013) 0.97
Effects of environmental enrichment on the incubation of cocaine craving. Neuropharmacology (2012) 0.97
CRACKing the histone code: cocaine's effects on chromatin structure and function. Horm Behav (2010) 0.96
Emergence of context-associated GluR(1) and ERK phosphorylation in the nucleus accumbens core during withdrawal from cocaine self-administration. Addict Biol (2011) 0.96
Epigenetic Readers of Lysine Acetylation Regulate Cocaine-Induced Plasticity. J Neurosci (2015) 0.96
Epigenetics and psychiatry. Neurotherapeutics (2013) 0.96
Long-lasting dysregulation of gene expression in corticostriatal circuits after repeated cocaine treatment in adult rats: effects on zif 268 and homer 1a. Eur J Neurosci (2009) 0.96
Association of time-dependent changes in mu opioid receptor mRNA, but not BDNF, TrkB, or MeCP2 mRNA and protein expression in the rat nucleus accumbens with incubation of heroin craving. Psychopharmacology (Berl) (2012) 0.96
Time-dependent decreases in nucleus accumbens AMPA/NMDA ratio and incubation of sucrose craving in adolescent and adult rats. Psychopharmacology (Berl) (2013) 0.96
Heroin self-administration: I. Incubation of goal-directed behavior in rats. Pharmacol Biochem Behav (2008) 0.95
Exercise as a potential treatment for drug abuse: evidence from preclinical studies. Front Psychiatry (2012) 0.94
Amphetamine-induced locomotion and gene expression are altered in BDNF heterozygous mice. Genes Brain Behav (2008) 0.94
Environmental enrichment counters cocaine abstinence-induced stress and brain reactivity to cocaine cues but fails to prevent the incubation effect. Addict Biol (2011) 0.93
Region-specific involvement of AMPA/Kainate receptors in Fos protein expression induced by cocaine-conditioned cues. Eur Neuropsychopharmacol (2008) 0.92
Blockade of dopamine D3 receptors in the nucleus accumbens and central amygdala inhibits incubation of cocaine craving in rats. Addict Biol (2012) 0.92
How the epigenome contributes to the development of psychiatric disorders. Dev Psychobiol (2010) 0.92
Epigenetics of drug abuse: predisposition or response. Pharmacogenomics (2012) 0.91
Rapamycin attenuates the expression of cocaine-induced place preference and behavioral sensitization. Addict Biol (2011) 0.90
Escalation of drug self-administration as a hallmark of persistent addiction liability. Behav Pharmacol (2013) 0.90
Multiple faces of BDNF in cocaine addiction. Behav Brain Res (2014) 0.90
The reinstatement model of drug relapse: history, methodology and major findings. Psychopharmacology (Berl) (2002) 9.90
Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival. Cell (2007) 6.13
Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving. Nature (2008) 6.01
MAM: more than just a housekeeper. Trends Cell Biol (2009) 4.27
Neurobiology of relapse to heroin and cocaine seeking: a review. Pharmacol Rev (2002) 4.23
Toward a model of drug relapse: an assessment of the validity of the reinstatement procedure. Psychopharmacology (Berl) (2006) 4.23
A memory retrieval-extinction procedure to prevent drug craving and relapse. Science (2012) 4.04
The pharmacology of sigma-1 receptors. Pharmacol Ther (2009) 3.12
Incubation of cocaine craving after withdrawal: a review of preclinical data. Neuropharmacology (2004) 2.99
Review. Context-induced relapse to drug seeking: a review. Philos Trans R Soc Lond B Biol Sci (2008) 2.98
Central amygdala ERK signaling pathway is critical to incubation of cocaine craving. Nat Neurosci (2005) 2.90
Cocaine experience establishes control of midbrain glutamate and dopamine by corticotropin-releasing factor: a role in stress-induced relapse to drug seeking. J Neurosci (2005) 2.76
Renewal of drug seeking by contextual cues after prolonged extinction in rats. Behav Neurosci (2002) 2.76
Neurobiology of the incubation of drug craving. Trends Neurosci (2011) 2.65
The HIV epidemic in Yunnan Province, China, 1989-2007. J Acquir Immune Defic Syndr (2010) 2.61
A single infusion of brain-derived neurotrophic factor into the ventral tegmental area induces long-lasting potentiation of cocaine seeking after withdrawal. J Neurosci (2004) 2.47
Dopamine uptake through the norepinephrine transporter in brain regions with low levels of the dopamine transporter: evidence from knock-out mouse lines. J Neurosci (2002) 2.46
Role of ERK in cocaine addiction. Trends Neurosci (2006) 2.43
Differential effects of blockade of dopamine D1-family receptors in nucleus accumbens core or shell on reinstatement of heroin seeking induced by contextual and discrete cues. J Neurosci (2007) 2.43
Ventral medial prefrontal cortex neuronal ensembles mediate context-induced relapse to heroin. Nat Neurosci (2011) 2.42
The anxiogenic drug yohimbine reinstates methamphetamine seeking in a rat model of drug relapse. Biol Psychiatry (2004) 2.41
Dominance of HIV-1 subtype CRF01_AE in sexually acquired cases leads to a new epidemic in Yunnan province of China. PLoS Med (2006) 2.37
Rodent BDNF genes, novel promoters, novel splice variants, and regulation by cocaine. Brain Res (2005) 2.34
Neurobiology of relapse to heroin and cocaine seeking: an update and clinical implications. Eur J Pharmacol (2005) 2.32
Targeted disruption of cocaine-activated nucleus accumbens neurons prevents context-specific sensitization. Nat Neurosci (2009) 2.30
Indoor air pollution and blood pressure in adult women living in rural China. Environ Health Perspect (2011) 2.25
A role of ventral tegmental area glutamate in contextual cue-induced relapse to heroin seeking. J Neurosci (2004) 2.23
The sigma-1 receptor chaperone as an inter-organelle signaling modulator. Trends Pharmacol Sci (2010) 2.11
Cocaine-experienced rats exhibit learning deficits in a task sensitive to orbitofrontal cortex lesions. Eur J Neurosci (2004) 2.08
Opiate versus psychostimulant addiction: the differences do matter. Nat Rev Neurosci (2011) 2.05
The reinstatement model of drug relapse: recent neurobiological findings, emerging research topics, and translational research. Psychopharmacology (Berl) (2013) 2.01
VIDEOS IN CLINICAL MEDICINE. Examination of the Retina. N Engl J Med (2015) 1.99
Role of ventral medial prefrontal cortex in incubation of cocaine craving. Neuropharmacology (2008) 1.99
Self-renewing endodermal progenitor lines generated from human pluripotent stem cells. Cell Stem Cell (2012) 1.94
Effect of environmental stressors on opiate and psychostimulant reinforcement, reinstatement and discrimination in rats: a review. Neurosci Biobehav Rev (2003) 1.93
The role of orbitofrontal cortex in drug addiction: a review of preclinical studies. Biol Psychiatry (2007) 1.89
Activation of group II metabotropic glutamate receptors in the nucleus accumbens shell attenuates context-induced relapse to heroin seeking. Neuropsychopharmacology (2005) 1.79
The CRF1 receptor antagonist antalarmin attenuates yohimbine-induced increases in operant alcohol self-administration and reinstatement of alcohol seeking in rats. Psychopharmacology (Berl) (2007) 1.74
Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia. Blood (2013) 1.73
Extensive primary repair of the thoracic aorta in acute type a aortic dissection by means of ascending aorta replacement combined with open placement of triple-branched stent graft: early results. Circulation (2010) 1.73
HIV and STIs in clients and female sex workers in mining regions of Gejiu City, China. Sex Transm Dis (2008) 1.72
Genetics of dopamine receptors and drug addiction: a comprehensive review. Behav Pharmacol (2009) 1.72
Molecular neuroadaptations in the accumbens and ventral tegmental area during the first 90 days of forced abstinence from cocaine self-administration in rats. J Neurochem (2003) 1.72
The anxiogenic drug yohimbine reinstates palatable food seeking in a rat relapse model: a role of CRF1 receptors. Neuropsychopharmacology (2005) 1.68
Sigma-1 receptors (sigma(1) binding sites) form raft-like microdomains and target lipid droplets on the endoplasmic reticulum: roles in endoplasmic reticulum lipid compartmentalization and export. J Pharmacol Exp Ther (2003) 1.67
Rare ADH variant constellations are specific for alcohol dependence. Alcohol Alcohol (2012) 1.66
Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving. Nat Neurosci (2013) 1.65
Effect of dopamine receptor antagonists on renewal of cocaine seeking by reexposure to drug-associated contextual cues. Neuropsychopharmacology (2002) 1.63
In vivo immune modulatory activity of hepatic stellate cells in mice. Hepatology (2006) 1.63
Intracellular dynamics of sigma-1 receptors (sigma(1) binding sites) in NG108-15 cells. J Pharmacol Exp Ther (2003) 1.61
Sigma-1 receptor ligands: potential in the treatment of neuropsychiatric disorders. CNS Drugs (2004) 1.60
Cocaine seeking over extended withdrawal periods in rats: different time courses of responding induced by cocaine cues versus cocaine priming over the first 6 months. Psychopharmacology (Berl) (2004) 1.59
Glycated albumin is superior to hemoglobin A1c for evaluating the presence and severity of coronary artery disease in type 2 diabetic patients. Cardiology (2012) 1.59
Withdrawal from cocaine self-administration produces long-lasting deficits in orbitofrontal-dependent reversal learning in rats. Learn Mem (2007) 1.59
Expansion of HIV/AIDS in China: lessons from Yunnan Province. Soc Sci Med (2006) 1.58
Role of projections from ventral medial prefrontal cortex to nucleus accumbens shell in context-induced reinstatement of heroin seeking. J Neurosci (2012) 1.56
The role of neuroadaptations in relapse to drug seeking. Nat Neurosci (2005) 1.51
The impact of orbitofrontal dysfunction on cocaine addiction. Nat Neurosci (2012) 1.50
Effects of stress on decision-making deficits in formerly heroin-dependent patients after different durations of abstinence. Am J Psychiatry (2011) 1.50
Systemic and central amygdala injections of the mGluR(2/3) agonist LY379268 attenuate the expression of incubation of cocaine craving. Biol Psychiatry (2006) 1.49
A meta-analysis of retention in methadone maintenance by dose and dosing strategy. Am J Drug Alcohol Abuse (2009) 1.49
Role of ventral tegmental area glial cell line-derived neurotrophic factor in incubation of cocaine craving. Biol Psychiatry (2009) 1.48
The neuropharmacology of relapse to food seeking: methodology, main findings, and comparison with relapse to drug seeking. Prog Neurobiol (2009) 1.48
New technologies for examining the role of neuronal ensembles in drug addiction and fear. Nat Rev Neurosci (2013) 1.45
Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration. Blood (2010) 1.44
Incubation of cue-induced cigarette craving during abstinence in human smokers. Biol Psychiatry (2011) 1.44
Increased serum HMGB1 level is associated with coronary artery disease in nondiabetic and type 2 diabetic patients. Atherosclerosis (2008) 1.43
Role of CRF and other neuropeptides in stress-induced reinstatement of drug seeking. Brain Res (2009) 1.42
Oxidized Low-Density Lipoprotein Promotes Macrophage Lipid Accumulation via the Toll-Like Receptor 4-Src Pathway. Circ J (2015) 1.42
Inhibition of PKMzeta in nucleus accumbens core abolishes long-term drug reward memory. J Neurosci (2011) 1.40
Central amygdala extracellular signal-regulated kinase signaling pathway is critical to incubation of opiate craving. J Neurosci (2008) 1.39
Relationship between full-thickness macular hole and retinal break/lattice degeneration. Eye Sci (2015) 1.39
Cocaine-induced CREB phosphorylation in nucleus accumbens of cocaine-sensitized rats is enabled by enhanced activation of extracellular signal-related kinase, but not protein kinase A. J Neurochem (2005) 1.39
Running is the neurogenic and neurotrophic stimulus in environmental enrichment. Learn Mem (2011) 1.36
Estimates of HIV prevalence in a highly endemic area of China: Dehong Prefecture, Yunnan Province. Int J Epidemiol (2008) 1.35
Effect of prazosin and guanfacine on stress-induced reinstatement of alcohol and food seeking in rats. Psychopharmacology (Berl) (2011) 1.33
Translational and reverse translational research on the role of stress in drug craving and relapse. Psychopharmacology (Berl) (2011) 1.33
Dynamic interaction between sigma-1 receptor and Kv1.2 shapes neuronal and behavioral responses to cocaine. Cell (2013) 1.31
Role of BDNF and GDNF in drug reward and relapse: a review. Neurosci Biobehav Rev (2009) 1.31
Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: implications for striatal neuronal function. Proc Natl Acad Sci U S A (2002) 1.30
Recent developments in animal models of drug relapse. Curr Opin Neurobiol (2013) 1.30
Understanding the molecular mechanism of sigma-1 receptors: towards a hypothesis that sigma-1 receptors are intracellular amplifiers for signal transduction. Curr Med Chem (2003) 1.28