Published in Blood on February 06, 2003
Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation. Blood (2011) 2.27
Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis. J Biol Chem (2009) 1.78
Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathway. J Immunol (2009) 1.70
Two distinct roles of mitogen-activated protein kinases in platelets and a novel Rac1-MAPK-dependent integrin outside-in retractile signaling pathway. Blood (2008) 1.47
Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3. Blood (2005) 1.44
Ginsenoside-Rp1 inhibits platelet activation and thrombus formation via impaired glycoprotein VI signalling pathway, tyrosine phosphorylation and MAPK activation. Br J Pharmacol (2012) 1.01
cGMP increases antioxidant function and attenuates oxidant cell death in mouse lung microvascular endothelial cells by a protein kinase G-dependent mechanism. Am J Physiol Lung Cell Mol Physiol (2010) 0.93
A rapid, PPAR-gamma-dependent effect of pioglitazone on the phosphorylation of MYPT. Am J Physiol Cell Physiol (2009) 0.92
Signaling-mediated functional activation of inducible nitric-oxide synthase and its role in stimulating platelet activation. J Biol Chem (2008) 0.92
Dual Roles of Quercetin in Platelets: Phosphoinositide-3-Kinase and MAP Kinases Inhibition, and cAMP-Dependent Vasodilator-Stimulated Phosphoprotein Stimulation. Evid Based Complement Alternat Med (2012) 0.88
Current concepts of platelet activation: possibilities for therapeutic modulation of heterotypic vs. homotypic aggregation. Br J Clin Pharmacol (2011) 0.86
Phosphodiesterase-5A (PDE5A) is localized to the endothelial caveolae and modulates NOS3 activity. Cardiovasc Res (2011) 0.83
Roles of cGMP/cGMP-dependent protein kinase in platelet activation. Blood (2004) 0.82
Conditional inactivation of Akt three isoforms causes tau hyperphosphorylation in the brain. Mol Neurodegener (2015) 0.78
Pistacia chinensis Methanolic Extract Attenuated MAPK and Akt Phosphorylations in ADP Stimulated Rat Platelets In Vitro. Evid Based Complement Alternat Med (2012) 0.78
Onion (Allium cepa L.) peel extract has anti-platelet effects in rat platelets. Springerplus (2015) 0.78
Staphylococcus aureus lipoteichoic acid inhibits platelet activation and thrombus formation via the Paf receptor. J Infect Dis (2013) 0.77
PPARγ agonists negatively regulate αIIbβ3 integrin outside-in signalling and platelet function through upregulation of protein kinase A activity. J Thromb Haemost (2016) 0.77
Pharmacological actions of nobiletin in the modulation of platelet function. Br J Pharmacol (2015) 0.77
BF066, a novel dual target antiplatelet agent without significant bleeding. PLoS One (2012) 0.77
Effect of Cordycepin-Enriched WIB801C from Cordyceps militaris Suppressing Fibrinogen Binding to Glycoprotein IIb/IIIa. Biomol Ther (Seoul) (2015) 0.76
Activation of Protein Kinase G (PKG) Reduces Neointimal Hyperplasia, Inhibits Platelet Aggregation, and Facilitates Re-endothelialization. Sci Rep (2016) 0.75
Signaling during platelet adhesion and activation. Arterioscler Thromb Vasc Biol (2010) 2.43
Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation. Blood (2011) 2.27
G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin "outside-in" signaling. Science (2010) 2.09
Suppression of endothelial progenitor cells in human coronary artery disease by the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine. J Am Coll Cardiol (2005) 1.99
Resistance to thienopyridines: clinical detection of coronary stent thrombosis by monitoring of vasodilator-stimulated phosphoprotein phosphorylation. Catheter Cardiovasc Interv (2003) 1.95
A molecular switch that controls cell spreading and retraction. J Cell Biol (2007) 1.93
A directional switch of integrin signalling and a new anti-thrombotic strategy. Nature (2013) 1.92
Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathway. J Immunol (2009) 1.70
Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases. J Biol Chem (2003) 1.63
A stimulatory role for cGMP-dependent protein kinase in platelet activation. Cell (2003) 1.54
Hearing evaluation of intratympanic methylprednisolone perfusion for refractory sudden sensorineural hearing loss. Otolaryngol Head Neck Surg (2010) 1.49
Two distinct roles of mitogen-activated protein kinases in platelets and a novel Rac1-MAPK-dependent integrin outside-in retractile signaling pathway. Blood (2008) 1.47
Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3. Blood (2005) 1.44
ADP-induced platelet aggregation frequently fails to detect impaired clopidogrel-responsiveness in patients with coronary artery disease compared to a P2Y12-specific assay. Thromb Haemost (2008) 1.40
G protein-dependent basal and evoked endothelial cell vWF secretion. Blood (2013) 1.39
IP-10 induces dissociation of newly formed blood vessels. J Cell Sci (2009) 1.38
A phosphoinositide 3-kinase-AKT-nitric oxide-cGMP signaling pathway in stimulating platelet secretion and aggregation. J Biol Chem (2006) 1.38
Critical roles for the COOH-terminal NITY and RGT sequences of the integrin beta3 cytoplasmic domain in inside-out and outside-in signaling. J Cell Biol (2003) 1.34
The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activation. Blood (2007) 1.33
Fibronectin mediates Opc-dependent internalization of Neisseria meningitidis in human brain microvascular endothelial cells. Mol Microbiol (2002) 1.33
Vasodilator-stimulated phosphoprotein regulates proliferation and growth inhibition by nitric oxide in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol (2004) 1.31
Inside-out, outside-in, and inside-outside-in: G protein signaling in integrin-mediated cell adhesion, spreading, and retraction. Curr Opin Cell Biol (2012) 1.21
A critical role for 14-3-3zeta protein in regulating the VWF binding function of platelet glycoprotein Ib-IX and its therapeutic implications. Blood (2005) 1.20
Tyrosine phosphorylation of the integrin beta 3 subunit regulates beta 3 cleavage by calpain. J Biol Chem (2006) 1.20
An important role for Akt3 in platelet activation and thrombosis. Blood (2011) 1.19
Rapid regulation of platelet activation in vivo by nitric oxide. Circulation (2004) 1.17
Stimulatory roles of nitric-oxide synthase 3 and guanylyl cyclase in platelet activation. J Biol Chem (2005) 1.16
Enhanced in vivo platelet adhesion in vasodilator-stimulated phosphoprotein (VASP)-deficient mice. Blood (2003) 1.13
Antioxidant treatment reduces blast-induced cochlear damage and hearing loss. Hear Res (2012) 1.12
Heat-shock protein gp96/grp94 is an essential chaperone for the platelet glycoprotein Ib-IX-V complex. Blood (2011) 1.12
Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway. Blood (2008) 1.11
On the roles of cGMP and glycoprotein Ib in platelet activation. Blood (2004) 1.10
Regulation of glycoprotein Ib-IX-von Willebrand factor interaction by cAMP-dependent protein kinase-mediated phosphorylation at Ser 166 of glycoprotein Ib(beta). J Biol Chem (2002) 1.09
Morphological and functional alterations of the cochlea in apolipoprotein E gene deficient mice. Hear Res (2005) 1.09
Interaction of Neisseria meningitidis with human brain microvascular endothelial cells: role of MAP- and tyrosine kinases in invasion and inflammatory cytokine release. Cell Microbiol (2004) 1.08
cDNA cloning and characterization of a novel gene encoding the MLF1-interacting protein MLF1IP. Oncogene (2004) 1.06
A platelet secretion pathway mediated by cGMP-dependent protein kinase. J Biol Chem (2004) 1.05
Neutrophil AKT2 regulates heterotypic cell-cell interactions during vascular inflammation. J Clin Invest (2014) 1.05
RGS3 interacts with 14-3-3 via the N-terminal region distinct from the RGS (regulator of G-protein signalling) domain. Biochem J (2002) 1.01
Novel role of the membrane-bound chemokine fractalkine in platelet activation and adhesion. Blood (2003) 1.01
An important role of the SRC family kinase Lyn in stimulating platelet granule secretion. J Biol Chem (2010) 1.00
Variable extent of clopidogrel responsiveness in patients after coronary stenting. Thromb Haemost (2004) 0.99
Vasodilator-stimulated phosphoprotein activation of serum-response element-dependent transcription occurs downstream of RhoA and is inhibited by cGMP-dependent protein kinase phosphorylation. J Biol Chem (2003) 0.99
Consistent up-regulation of Stat3 Independently of Jak2 mutations in a new murine model of essential thrombocythemia. Cancer Res (2009) 0.98
Regulation of leukocyte degranulation by cGMP-dependent protein kinase and phosphoinositide 3-kinase: potential roles in phosphorylation of target membrane SNARE complex proteins in rat mast cells. J Immunol (2007) 0.97
Gene expression pattern in human brain endothelial cells in response to Neisseria meningitidis. Infect Immun (2006) 0.96
A critical role for Lyn kinase in strengthening endothelial integrity and barrier function. Blood (2013) 0.95
Antioxidants reduce cellular and functional changes induced by intense noise in the inner ear and cochlear nucleus. J Assoc Res Otolaryngol (2014) 0.93
Reduced vascular NO bioavailability in diabetes increases platelet activation in vivo. Arterioscler Thromb Vasc Biol (2004) 0.93
Soluble guanylyl cyclase activation with HMR1766 attenuates platelet activation in diabetic rats. Arterioscler Thromb Vasc Biol (2006) 0.93
Rosuvastatin reduces platelet activation in heart failure: role of NO bioavailability. Arterioscler Thromb Vasc Biol (2005) 0.93
The role of Rac1 in glycoprotein Ib-IX-mediated signal transduction and integrin activation. Arterioscler Thromb Vasc Biol (2012) 0.92
Signaling-mediated functional activation of inducible nitric-oxide synthase and its role in stimulating platelet activation. J Biol Chem (2008) 0.92
Cyclic nucleotide-regulated proliferation and differentiation vary in human hematopoietic progenitor cells derived from healthy persons, tumor patients, and chronic myelocytic leukemia patients. Stem Cells Dev (2008) 0.91
ADP-stimulated activation of Akt during integrin outside-in signaling promotes platelet spreading by inhibiting glycogen synthase kinase-3β. Arterioscler Thromb Vasc Biol (2012) 0.91
Role for platelet glycoprotein Ib-IX and effects of its inhibition in endotoxemia-induced thrombosis, thrombocytopenia, and mortality. Arterioscler Thromb Vasc Biol (2013) 0.89
LIM kinase-1 selectively promotes glycoprotein Ib-IX-mediated TXA2 synthesis, platelet activation, and thrombosis. Blood (2013) 0.88
Tetrahydroxystilbene glucoside improves the learning and memory of amyloid-β(₁₋₄₂)-injected rats and may be connected to synaptic changes in the hippocampus. Can J Physiol Pharmacol (2012) 0.87
Impaired stria vascularis in the inner ear of apolipoprotein E gene knockout mice. ORL J Otorhinolaryngol Relat Spec (2008) 0.86
Effects of delayed and extended antioxidant treatment on acute acoustic trauma. Free Radic Res (2011) 0.85
The CX3C chemokine fractalkine induces vascular dysfunction by generation of superoxide anions. Arterioscler Thromb Vasc Biol (2006) 0.84
Opposing effects of platelet-activating factor and lyso-platelet-activating factor on neutrophil and platelet activation. Mol Pharmacol (2008) 0.84
Increased noise sensitivity and altered inner ear MENA distribution in VASP-/- mice. Cell Tissue Res (2004) 0.83
Reduced basal nitric oxide bioavailability and platelet activation in young spontaneously hypertensive rats. Biochem Pharmacol (2004) 0.83
Effects of simvastatin on plasma lipoproteins and hearing loss in apolipoprotein E gene-deficient mice. ORL J Otorhinolaryngol Relat Spec (2009) 0.82
Group B streptococcus isolates from septic patients and healthy carriers differentially activate platelet signaling cascades. Thromb Haemost (2006) 0.82
Expanding the spectrum of PTH1R mutations in patients with primary failure of tooth eruption. Clin Oral Investig (2013) 0.82
Hyperprolactinemia in patients on antipsychotic drugs causes ADP-stimulated platelet activation that might explain the increased risk for venous thromboembolism: pilot study. J Clin Psychopharmacol (2003) 0.82
Infection of human coronary artery endothelial cells by group B streptococcus contributes to dysregulation of apoptosis, hemostasis, and innate immune responses. Mediators Inflamm (2011) 0.82
Phosphatidylserine surface expression and integrin alpha IIb beta 3 activity on thrombin/convulxin stimulated platelets/particles of different sizes. Br J Haematol (2008) 0.81
Treatment of subjective tinnitus: a comparative clinical study of intratympanic steroid injection vs. oral carbamazepine. Med Sci Monit (2009) 0.81
Inhibition of platelet activation in congestive heart failure by aldosterone receptor antagonism and ACE inhibition. Thromb Haemost (2003) 0.80
Tetrahydroxystilbene glucoside improves learning and (or) memory ability of aged rats and may be connected to the APP pathway. Can J Physiol Pharmacol (2011) 0.79
Increased platelet activation in young Zucker rats with impaired glucose tolerance is improved by acarbose. Thromb Haemost (2004) 0.79
Enhanced platelet activation by prolactin in patients with ischemic stroke. Thromb Haemost (2006) 0.78
The 14-3-3zeta-GPIb-IX-V complex as an antiplatelet target. Drug News Perspect (2007) 0.78
Platelet activation in heart failure. Clin Lab (2004) 0.78
Induction of tolerance by oral administration of beta-tubulin in an animal model of autoimmune inner ear disease. ORL J Otorhinolaryngol Relat Spec (2009) 0.78
Hearing development and spiral ganglion neurite growth in VASP deficient mice. Brain Res (2007) 0.78
TA205, an anti-talin monoclonal antibody, inhibits integrin-talin interaction. FEBS Lett (2006) 0.78
Delayed formation of actin filaments in the outer pillar head plate of VASP-/- mice. Cells Tissues Organs (2006) 0.78
Inhibition of platelet activation in rats with severe congestive heart failure by a novel endothelial nitric oxide synthase transcription enhancer. Eur J Heart Fail (2009) 0.77
Severe neutropenia under clopidogrel treatment three weeks after coronary stenting. Thromb Haemost (2007) 0.77
Association study between C7673T polymorphism in apolipoprotein B gene and cerebral infarction with family history in a Chinese population. Neurol India (2009) 0.77
Neisseria meningitidis induces platelet inhibition and increases vascular endothelial permeability via nitric oxide regulated pathways. Thromb Haemost (2011) 0.76
Relationship of glucocorticoid receptor expression in peripheral blood mononuclear cells and the cochlea of guinea pigs and effects of dexamethasone administration. PLoS One (2013) 0.75
Small tympanic membrane perforations in the inferior quadrants do not impact the manubrium vibration in guinea pigs. PLoS One (2012) 0.75
Expression of VASP and zyxin in cochlear pillar cells: indication for actin-based dynamics? Cell Tissue Res (2003) 0.75
Late thrombosis of a drug-eluting stent during combined anti-platelet therapy in a clopidogrel nonresponsive diabetic patient: shall we routinely test platelet function? Thromb Haemost (2007) 0.75
Association of protein Z and factor VII gene polymorphisms with risk of cerebral hemorrhage: a case-control and a family-based association study in a Chinese Han population. J Genet (2016) 0.75
[Reconsideration of tinnitus diagnosis and treatment]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi (2014) 0.75
[A short term study on the efficacies of intratympanic prednisolone and dexamethasone injection for subjective tinnitus]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi (2008) 0.75
High resolution flash three-dimensional LIDAR systems based on polarization modulation. Appl Opt (2017) 0.75
[Clopidogrel--clinical use and potential therapeutic problems]. Herz (2008) 0.75