Published in J Immunol on June 15, 2009
Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4. Blood (2011) 3.25
Thrombosis as an intravascular effector of innate immunity. Nat Rev Immunol (2012) 2.98
Platelets as cellular effectors of inflammation in vascular diseases. Circ Res (2013) 2.62
Cellular fibronectin containing extra domain A promotes arterial thrombosis in mice through platelet Toll-like receptor 4. Blood (2015) 1.50
Platelets in defense against bacterial pathogens. Cell Mol Life Sci (2009) 1.35
Platelet activation attracts a subpopulation of effector monocytes to sites of Leishmania major infection. J Exp Med (2011) 1.28
Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum. Semin Immunopathol (2011) 1.26
Engagement of platelet toll-like receptor 9 by novel endogenous ligands promotes platelet hyperreactivity and thrombosis. Circ Res (2012) 1.24
The septic milieu triggers expression of spliced tissue factor mRNA in human platelets. J Thromb Haemost (2011) 1.15
Nucleotide-binding oligomerization domain 2 receptor is expressed in platelets and enhances platelet activation and thrombosis. Circulation (2015) 1.12
Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway. Nat Commun (2013) 1.05
Thrombocytopenia in Dengue: Interrelationship between Virus and the Imbalance between Coagulation and Fibrinolysis and Inflammatory Mediators. Mediators Inflamm (2015) 1.05
Platelets as immune mediators: their role in host defense responses and sepsis. Thromb Res (2010) 1.04
Crosstalk between Platelets and the Immune System: Old Systems with New Discoveries. Adv Hematol (2012) 1.01
Platelet function beyond hemostasis and thrombosis. Curr Opin Hematol (2013) 0.96
Cantharidin and norcantharidin inhibit the ability of MCF-7 cells to adhere to platelets via protein kinase C pathway-dependent downregulation of α2 integrin. Oncol Rep (2013) 0.96
Inhibition of MCF-7 breast cancer cell-induced platelet aggregation using a combination of antiplatelet drugs. Oncol Lett (2012) 0.94
Bacterial Adaptation during Chronic Respiratory Infections. Pathogens (2015) 0.92
Do aspirin and other antiplatelet drugs reduce the mortality in critically ill patients? Thrombosis (2011) 0.92
Lipopolysaccharide stimulates platelets through an IL-1β autocrine loop. J Immunol (2013) 0.91
Platelet-derived HMGB1 is a critical mediator of thrombosis. J Clin Invest (2015) 0.91
The role of inflammation in regulating platelet production and function: Toll-like receptors in platelets and megakaryocytes. Thromb Res (2009) 0.90
Platelets and infections - complex interactions with bacteria. Front Immunol (2015) 0.90
Platelet-derived Toll-like receptor 4 (Tlr-4) is sufficient to promote microvascular thrombosis in endotoxemia. PLoS One (2012) 0.89
Role for platelet glycoprotein Ib-IX and effects of its inhibition in endotoxemia-induced thrombosis, thrombocytopenia, and mortality. Arterioscler Thromb Vasc Biol (2013) 0.89
The Inflammatory Role of Platelets via Their TLRs and Siglec Receptors. Front Immunol (2015) 0.88
Cardiotoxicity during invasive pneumococcal disease. Am J Respir Crit Care Med (2015) 0.86
Genetic deletion of toll-like receptor 4 on platelets attenuates experimental pulmonary hypertension. Circ Res (2014) 0.86
Down-regulation of platelet surface CD47 expression in Escherichia coli O157:H7 infection-induced thrombocytopenia. PLoS One (2009) 0.85
Sex differences in platelet toll-like receptors and their association with cardiovascular risk factors. Arterioscler Thromb Vasc Biol (2015) 0.84
P2X7 receptor activation contributes to an initial upstream mechanism of lipopolysaccharide-induced vascular dysfunction. Clin Sci (Lond) (2013) 0.84
Clopidogrel treatment and the incidence and severity of community acquired pneumonia in a cohort study and meta-analysis of antiplatelet therapy in pneumonia and critical illness. J Thromb Thrombolysis (2013) 0.84
Effect of dietary supplementation of procyanidin on growth performance and immune response in pigs. Asian-Australas J Anim Sci (2014) 0.83
The role of calpain-myosin 9-Rab7b pathway in mediating the expression of Toll-like receptor 4 in platelets: a novel mechanism involved in α-granules trafficking. PLoS One (2014) 0.83
Procoagulatory state in inflammatory bowel diseases is promoted by impaired intestinal barrier function. Gastroenterol Res Pract (2015) 0.83
Review of cellular and molecular pathways linking thrombosis and innate immune system during sepsis. J Res Med Sci (2010) 0.82
Human coagulation factor X-adenovirus type 5 complexes poorly stimulate an innate immune response in human mononuclear phagocytes. J Virol (2014) 0.81
Leukocyte- and platelet-derived microvesicle interactions following in vitro and in vivo activation of toll-like receptor 4 by lipopolysaccharide. PLoS One (2011) 0.80
Type 2 scavenger receptor CD36 in platelet activation: the role of hyperlipemia and oxidative stress. Clin Lipidol (2009) 0.79
Inflammation and thrombosis in cardiovascular disease. Curr Opin Hematol (2013) 0.79
Suppressive effect of exogenous carbon monoxide on endotoxin-stimulated platelet over-activation via the glycoprotein-mediated PI3K-Akt-GSK3β pathway. Sci Rep (2016) 0.78
Reactive oxygen and nitrogen species in sepsis-induced hepatic microvascular dysfunction. Inflamm Res (2012) 0.78
LPS stimulation of purified human platelets is partly dependent on plasma soluble CD14 to secrete their main secreted product, soluble-CD40-Ligand. BMC Immunol (2015) 0.78
Kinase activity profiling of gram-negative pneumonia. Mol Med (2011) 0.78
Amelioration of murine passive immune thrombocytopenia by IVIg and a therapeutic monoclonal CD44 antibody does not require the Myd88 signaling pathway. PLoS One (2013) 0.78
Slowed decay of mRNAs enhances platelet specific translation. Blood (2017) 0.78
Toll-like receptor 4 regulates platelet function and contributes to coagulation abnormality and organ injury in hemorrhagic shock and resuscitation. Circ Cardiovasc Genet (2014) 0.77
P2Y12 Receptor Modulates Sepsis-Induced Inflammation. Arterioscler Thromb Vasc Biol (2016) 0.77
Calpain activity and Toll-like receptor 4 expression in platelet regulate haemostatic situation in patients undergoing cardiac surgery and coagulation in mice. Mediators Inflamm (2014) 0.76
Suppressive effect of CORM-2 on LPS-induced platelet activation by glycoprotein mediated HS1 phosphorylation interference. PLoS One (2013) 0.76
Expression and functionality of Toll-like receptor 3 in the megakaryocytic lineage. J Thromb Haemost (2015) 0.76
Antiplatelet antibody may cause delayed transfusion-related acute lung injury. Int J Gen Med (2011) 0.76
Elevated Toll-Like Receptor-Induced CXCL8 Secretion in Human Blood Basophils from Allergic Donors Is Independent of Toll-Like Receptor Expression Levels. PLoS One (2016) 0.76
Intercellular Interactions as Regulators of NETosis. Front Immunol (2016) 0.75
Annexin A5 increases survival in murine sepsis model by inhibiting HMGB1-mediated pro-inflammation and coagulation. Mol Med (2016) 0.75
Non-Lethal Endotoxin Injection: A Rat Model of Hypercoagulability. PLoS One (2017) 0.75
Platelets in neutrophil recruitment to sites of inflammation. Curr Opin Hematol (2017) 0.75
New Concepts and Mechanisms of Platelet Activation Signaling. Physiology (Bethesda) (2017) 0.75
Toll-Like Receptor Signalling Is Not Involved in Platelet Response to Streptococcus pneumoniae In Vitro or In Vivo. PLoS One (2016) 0.75
NF-κB Links TLR2 and PAR1 to Soluble Immunomodulator Factor Secretion in Human Platelets. Front Immunol (2017) 0.75
TLR2 Plays a Key Role in Platelet Hyperreactivity and Accelerated Thrombosis Associated with Hyperlipidemia. Circ Res (2017) 0.75
A Randomized Placebo Controlled Trial of Aspirin Effects on Immune Activation in Chronically Human Immunodeficiency Virus-Infected Adults on Virologically Suppressive Antiretroviral Therapy. Open Forum Infect Dis (2017) 0.75
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science (1998) 37.15
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature (1997) 23.92
CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science (1990) 17.86
Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity (1999) 11.64
Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat Med (2007) 8.58
Structure and function of lipopolysaccharide binding protein. Science (1990) 7.76
Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism. Nat Immunol (2001) 4.13
Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4. Immunology (2004) 4.09
Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation. Nature (2008) 3.14
Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4. J Lipid Res (2006) 2.85
Ligands "activate" integrin alpha IIb beta 3 (platelet GPIIb-IIIa). Cell (1991) 2.81
Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both toll-like receptors 2 and 4. Infect Immun (2004) 2.74
Platelets express functional Toll-like receptor-4. Blood (2005) 2.37
TIR domain-containing adaptors define the specificity of TLR signaling. Mol Immunol (2004) 2.26
TLR4 signaling induces TLR2 expression in endothelial cells via neutrophil NADPH oxidase. J Clin Invest (2003) 2.16
Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-alpha production in vivo. Blood (2005) 2.03
Immediate effects of intravenous endotoxin on serotonin concentrations and blood platelets. Circ Res (1960) 1.84
A family of lipopolysaccharide binding proteins involved in responses to gram-negative sepsis. J Biol Chem (1988) 1.79
Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases. J Biol Chem (2003) 1.63
Lipopolysaccharides of Bacteroides fragilis, Chlamydia trachomatis and Pseudomonas aeruginosa signal via toll-like receptor 2. J Med Microbiol (2004) 1.63
Evidence of Toll-like receptor molecules on human platelets. Immunol Cell Biol (2005) 1.58
A stimulatory role for cGMP-dependent protein kinase in platelet activation. Cell (2003) 1.54
A phosphoinositide 3-kinase-AKT-nitric oxide-cGMP signaling pathway in stimulating platelet secretion and aggregation. J Biol Chem (2006) 1.38
Platelet function in sepsis. Crit Care Med (2002) 1.29
Nitric oxide released from activated platelets inhibits platelet recruitment. J Clin Invest (1997) 1.28
Endotoxin enhances microvascular thrombosis in mouse cremaster venules via a TLR4-dependent, neutrophil-independent mechanism. Am J Physiol Heart Circ Physiol (2005) 1.27
Lipopolysaccharide is a direct agonist for platelet RNA splicing. J Immunol (2008) 1.24
Increased adhesion and aggregation of platelets lacking cyclic guanosine 3',5'-monophosphate kinase I. J Exp Med (1999) 1.24
Agonists of toll-like receptor (TLR)2 and TLR4 are unable to modulate platelet activation by adenosine diphosphate and platelet activating factor. Thromb Haemost (2005) 1.23
Stimulatory roles of nitric-oxide synthase 3 and guanylyl cyclase in platelet activation. J Biol Chem (2005) 1.16
Toll-like receptor 4 ligand can differentially modulate the release of cytokines by human platelets. Br J Haematol (2008) 1.12
A platelet secretion pathway mediated by cGMP-dependent protein kinase. J Biol Chem (2004) 1.05
Effects of a variety of endotoxins on human and rabbit platelet function. Thromb Diath Haemorrh (1971) 1.05
LPS-induced platelet response and rapid shock in mice: contribution of O-antigen region of LPS and involvement of the lectin pathway of the complement system. Blood (2002) 1.04
Aggregation behavior of an ultra-pure lipopolysaccharide that stimulates TLR-4 receptors. Biophys J (2008) 1.01
Platelet-bound lipopolysaccharide enhances Fc receptor-mediated phagocytosis of IgG-opsonized platelets. Blood (2007) 0.99
Mechanisms of the priming effect of low doses of lipopoly-saccharides on leukocyte-dependent platelet aggregation in whole blood. Thromb Haemost (2003) 0.97
Compensatory mechanisms influence hemostasis in setting of eNOS deficiency. Am J Physiol Heart Circ Physiol (2004) 0.96
Regulation of cementoblast function by P. gingivalis lipopolysaccharide via TLR2. J Dent Res (2006) 0.92
Endotoxin concentration in neutropenic patients with suspected gram-negative sepsis: correlation with clinical outcome and determination of anti-endotoxin core antibodies during therapy with polyclonal immunoglobulin M-enriched immunoglobulins. Antimicrob Agents Chemother (1992) 0.92
Beneficial effect of glycoprotein IIb/IIIa inhibitor (AZ-1) on endothelium in Escherichia coli endotoxin-induced shock. Crit Care Med (2001) 0.90
Complement-dependent accumulation and degradation of platelets in the lung and liver induced by injection of lipopolysaccharides. Infect Immun (1999) 0.89
Contrasting effects of lipopolysaccharides (endotoxins) from oral black-pigmented bacteria and Enterobacteriaceae on platelets, a major source of serotonin, and on histamine-forming enzyme in mice. J Infect Dis (1997) 0.88
The antiplatelet activity of Escherichia coli lipopolysaccharide is mediated through a nitric oxide/cyclic GMP pathway. Eur J Haematol (1999) 0.83
Effect of gram-negative bacterial lipopolysaccharide-derived polysaccharides, glycolipids, and lipopolysaccharides on rabbit and human platelets in vitro. Immunobiology (1980) 0.79
SOAPdenovo2: an empirically improved memory-efficient short-read de novo assembler. Gigascience (2012) 20.89
Assemblathon 1: a competitive assessment of de novo short read assembly methods. Genome Res (2011) 8.38
The genome of the mesopolyploid crop species Brassica rapa. Nat Genet (2011) 8.23
Signaling mechanisms regulating endothelial permeability. Physiol Rev (2006) 7.63
Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species. Gigascience (2013) 4.11
Regulation of endothelial junctional permeability. Ann N Y Acad Sci (2008) 3.39
NF-kappa B activation as a pathological mechanism of septic shock and inflammation. Am J Physiol Lung Cell Mol Physiol (2006) 3.15
Impairment of store-operated Ca2+ entry in TRPC4(-/-) mice interferes with increase in lung microvascular permeability. Circ Res (2002) 3.05
Regulation of endothelial permeability via paracellular and transcellular transport pathways. Annu Rev Physiol (2010) 2.86
Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage. Nat Cell Biol (2006) 2.85
Reactive oxygen species in inflammation and tissue injury. Antioxid Redox Signal (2013) 2.59
Signaling during platelet adhesion and activation. Arterioscler Thromb Vasc Biol (2010) 2.43
NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology. Antioxid Redox Signal (2009) 2.29
Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation. Blood (2011) 2.27
Role of TRPM2 channel in mediating H2O2-induced Ca2+ entry and endothelial hyperpermeability. Circ Res (2007) 2.24
Caveolin regulation of endothelial function. Am J Physiol Lung Cell Mol Physiol (2003) 2.22
TLR4 signaling induces TLR2 expression in endothelial cells via neutrophil NADPH oxidase. J Clin Invest (2003) 2.16
Toll-like receptor-4 (TLR4) signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors. Nat Med (2003) 2.14
G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin "outside-in" signaling. Science (2010) 2.09
Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration. J Clin Invest (2009) 2.02
pIRS: Profile-based Illumina pair-end reads simulator. Bioinformatics (2012) 2.00
RhoGDI-1 modulation of the activity of monomeric RhoGTPase RhoA regulates endothelial barrier function in mouse lungs. Circ Res (2007) 1.99
Neutrophil caveolin-1 expression contributes to mechanism of lung inflammation and injury. Am J Physiol Lung Cell Mol Physiol (2007) 1.97
Role of Src-induced dynamin-2 phosphorylation in caveolae-mediated endocytosis in endothelial cells. J Biol Chem (2004) 1.94
A molecular switch that controls cell spreading and retraction. J Cell Biol (2007) 1.93
Novel mechanism of endothelial nitric oxide synthase activation mediated by caveolae internalization in endothelial cells. Circ Res (2006) 1.92
Serum amyloid A induces IL-8 secretion through a G protein-coupled receptor, FPRL1/LXA4R. Blood (2002) 1.92
A directional switch of integrin signalling and a new anti-thrombotic strategy. Nature (2013) 1.92
Caveolin-1 regulates store-operated Ca2+ influx by binding of its scaffolding domain to transient receptor potential channel-1 in endothelial cells. Mol Pharmacol (2006) 1.92
Cutting edge: TLR2 is a functional receptor for acute-phase serum amyloid A. J Immunol (2008) 1.89
Toll-like receptor 4 mediates neutrophil sequestration and lung injury induced by endotoxin and hyperinflation. Crit Care Med (2010) 1.87
Caveolin-1 regulates NF-kappaB activation and lung inflammatory response to sepsis induced by lipopolysaccharide. J Immunol (2006) 1.86
Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells. Circ Res (2008) 1.85
COPE: an accurate k-mer-based pair-end reads connection tool to facilitate genome assembly. Bioinformatics (2012) 1.83
Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization. Proc Natl Acad Sci U S A (2007) 1.81
Quantitative analysis of albumin uptake and transport in the rat microvessel endothelial monolayer. Am J Physiol Lung Cell Mol Physiol (2003) 1.81
Caveolin-1 scaffold domain interacts with TRPC1 and IP3R3 to regulate Ca2+ store release-induced Ca2+ entry in endothelial cells. Am J Physiol Cell Physiol (2008) 1.80
Suppression of RhoA activity by focal adhesion kinase-induced activation of p190RhoGAP: role in regulation of endothelial permeability. J Biol Chem (2005) 1.74
Protein kinase C-delta (PKC-delta ) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727. J Biol Chem (2002) 1.72
Endothelial cell-restricted disruption of FoxM1 impairs endothelial repair following LPS-induced vascular injury. J Clin Invest (2006) 1.71
Ca2+ signaling, TRP channels, and endothelial permeability. Microcirculation (2006) 1.70
Role of Ca2+ signaling in the regulation of endothelial permeability. Vascul Pharmacol (2002) 1.69
Dual regulation of endothelial junctional permeability. Sci STKE (2007) 1.67
Synthesis and anti-HIV activity evaluation of 2-(4-(naphthalen-2-yl)-1,2,3-thiadiazol-5-ylthio)-N-acetamides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. Eur J Med Chem (2009) 1.64
Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases. J Biol Chem (2003) 1.63
Intercellular adhesion molecule-1-dependent neutrophil adhesion to endothelial cells induces caveolae-mediated pulmonary vascular hyperpermeability. Circ Res (2008) 1.63
Role of NADPH oxidase in the mechanism of lung neutrophil sequestration and microvessel injury induced by Gram-negative sepsis: studies in p47phox-/- and gp91phox-/- mice. J Immunol (2002) 1.60
Serum amyloid A is an endogenous ligand that differentially induces IL-12 and IL-23. J Immunol (2006) 1.57
ATM activates p53 by regulating MDM2 oligomerization and E3 processivity. EMBO J (2009) 1.56
Increased pulmonary vascular resistance and defective pulmonary artery filling in caveolin-1-/- mice. Am J Physiol Lung Cell Mol Physiol (2008) 1.56
The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation. Nat Immunol (2011) 1.55
Constitutive eNOS-derived nitric oxide is a determinant of endothelial junctional integrity. Am J Physiol Lung Cell Mol Physiol (2005) 1.54
A stimulatory role for cGMP-dependent protein kinase in platelet activation. Cell (2003) 1.54
Protein kinase Calpha phosphorylates the TRPC1 channel and regulates store-operated Ca2+ entry in endothelial cells. J Biol Chem (2004) 1.53
Molecular determinants of endothelial transcytosis and their role in endothelial permeability. Am J Physiol Lung Cell Mol Physiol (2007) 1.53
Sphingosine 1-phosphate-induced mobilization of intracellular Ca2+ mediates rac activation and adherens junction assembly in endothelial cells. J Biol Chem (2005) 1.52
Nonmuscle myosin light-chain kinase mediates neutrophil transmigration in sepsis-induced lung inflammation by activating beta2 integrins. Nat Immunol (2008) 1.51
Regulation of surfactant secretion in alveolar type II cells. Am J Physiol Lung Cell Mol Physiol (2007) 1.50
Protein kinase Calpha-induced p115RhoGEF phosphorylation signals endothelial cytoskeletal rearrangement. J Biol Chem (2003) 1.50
Phosphatidylinositol 3-kinase gamma signaling through protein kinase Czeta induces NADPH oxidase-mediated oxidant generation and NF-kappaB activation in endothelial cells. J Biol Chem (2006) 1.49
Hearing evaluation of intratympanic methylprednisolone perfusion for refractory sudden sensorineural hearing loss. Otolaryngol Head Neck Surg (2010) 1.49
siRNA-induced caveolin-1 knockdown in mice increases lung vascular permeability via the junctional pathway. Am J Physiol Lung Cell Mol Physiol (2005) 1.48
Two distinct roles of mitogen-activated protein kinases in platelets and a novel Rac1-MAPK-dependent integrin outside-in retractile signaling pathway. Blood (2008) 1.47
Serum amyloid A induces G-CSF expression and neutrophilia via Toll-like receptor 2. Blood (2008) 1.46
PKCzeta regulates TNF-alpha-induced activation of NADPH oxidase in endothelial cells. Circ Res (2002) 1.46
Angiopoietin-1 opposes VEGF-induced increase in endothelial permeability by inhibiting TRPC1-dependent Ca2 influx. Circ Res (2005) 1.44
Galphaq-TRPC6-mediated Ca2+ entry induces RhoA activation and resultant endothelial cell shape change in response to thrombin. J Biol Chem (2006) 1.44
Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3. Blood (2005) 1.44
Tumor necrosis factor-alpha induces early-onset endothelial adhesivity by protein kinase Czeta-dependent activation of intercellular adhesion molecule-1. Circ Res (2003) 1.44
Bidirectional regulation of neutrophil migration by mitogen-activated protein kinases. Nat Immunol (2012) 1.43
RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability. J Biol Chem (2003) 1.43
Tumor necrosis factor-alpha-induced TRPC1 expression amplifies store-operated Ca2+ influx and endothelial permeability. Am J Physiol Lung Cell Mol Physiol (2004) 1.41
Recurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections. Am J Hum Genet (2013) 1.40
G protein-dependent basal and evoked endothelial cell vWF secretion. Blood (2013) 1.39
IP-10 induces dissociation of newly formed blood vessels. J Cell Sci (2009) 1.38
A phosphoinositide 3-kinase-AKT-nitric oxide-cGMP signaling pathway in stimulating platelet secretion and aggregation. J Biol Chem (2006) 1.38
RNA interference targeting transforming growth factor-beta type II receptor suppresses ocular inflammation and fibrosis. Mol Vis (2004) 1.36
Galpha(q) and Gbetagamma regulate PAR-1 signaling of thrombin-induced NF-kappaB activation and ICAM-1 transcription in endothelial cells. Circ Res (2002) 1.36
Critical roles for the COOH-terminal NITY and RGT sequences of the integrin beta3 cytoplasmic domain in inside-out and outside-in signaling. J Cell Biol (2003) 1.34
The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activation. Blood (2007) 1.33
Size and dynamics of caveolae studied using nanoparticles in living endothelial cells. ACS Nano (2009) 1.33
SirT1 is an inhibitor of proliferation and tumor formation in colon cancer. J Biol Chem (2009) 1.33
Emodin enhances arsenic trioxide-induced apoptosis via generation of reactive oxygen species and inhibition of survival signaling. Cancer Res (2004) 1.33
Cdc42 regulates the restoration of endothelial barrier function. Circ Res (2003) 1.31
Gbetagamma activation of Src induces caveolae-mediated endocytosis in endothelial cells. J Biol Chem (2004) 1.31