Published in Blood on June 07, 2005
Platelet glycoprotein Ib alpha supports experimental lung metastasis. Proc Natl Acad Sci U S A (2007) 1.68
Signaling-mediated cooperativity between glycoprotein Ib-IX and protease-activated receptors in thrombin-induced platelet activation. Blood (2015) 1.48
Glycoprotein Ibalpha forms disulfide bonds with 2 glycoprotein Ibbeta subunits in the resting platelet. Blood (2006) 1.39
The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activation. Blood (2007) 1.33
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The membrane-proximal intermolecular disulfide bonds in glycoprotein Ib influence receptor binding to von Willebrand factor. J Thromb Haemost (2008) 0.89
LIM kinase-1 selectively promotes glycoprotein Ib-IX-mediated TXA2 synthesis, platelet activation, and thrombosis. Blood (2013) 0.88
Effect of statins on platelet function in patients with hyperlipidemia. Arch Med Sci (2013) 0.84
Modularity of the oncoprotein-like properties of platelet glycoprotein Ibalpha. J Biol Chem (2008) 0.82
Platelet interaction with von Willebrand factor is enhanced by shear-induced clustering of glycoprotein Ibα. Haematologica (2013) 0.80
Analysis of inter-subunit contacts reveals the structural malleability of extracellular domains in platelet glycoprotein Ib-IX complex. J Thromb Haemost (2014) 0.80
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Accessible Synthetic Probes for Staining Actin inside Platelets and Megakaryocytes by Employing Lifeact Peptide. Chembiochem (2015) 0.75
14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function. Nat Commun (2016) 0.75
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Cooperative unfolding of distinctive mechanoreceptor domains transduces force into signals. Elife (2016) 0.75
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Phosphoinositide 3-kinase forms a complex with platelet membrane glycoprotein Ib-IX-V complex and 14-3-3zeta. Blood (2000) 1.11
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14-3-3 zeta mediates integrin-induced activation of Cdc42 and Rac. Platelet glycoprotein Ib-IX regulates integrin-induced signaling by sequestering 14-3-3 zeta. J Biol Chem (2003) 1.09
A novel ligand-binding site in the zeta-form 14-3-3 protein recognizing the platelet glycoprotein Ibalpha and distinct from the c-Raf-binding site. J Biol Chem (1998) 1.08
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The cytoplasmic domain of glycoprotein (GP) Ibalpha constrains the lateral diffusion of the GP Ib-IX complex and modulates von Willebrand factor binding. Biochemistry (1997) 1.03
Association of a phospholipase A2 (14-3-3 protein) with the platelet glycoprotein Ib-IX complex. J Biol Chem (1994) 1.02
A murine antiglycoprotein Ib complex monoclonal antibody, SZ 2, inhibits platelet aggregation induced by both ristocetin and collagen. Blood (1987) 1.01
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Identification of a novel 14-3-3zeta binding site within the cytoplasmic tail of platelet glycoprotein Ibalpha. Blood (2004) 0.99
Interaction of calmodulin with the cytoplasmic domain of the platelet membrane glycoprotein Ib-IX-V complex. Blood (2001) 0.99
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Signaling across the platelet adhesion receptor glycoprotein Ib-IX induces alpha IIbbeta 3 activation both in platelets and a transfected Chinese hamster ovary cell system. J Biol Chem (2000) 0.97
Identification of a region in the cytoplasmic domain of the platelet membrane glycoprotein Ib-IX complex that binds to purified actin-binding protein. J Biol Chem (1992) 0.92
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Cytoplasmic domains of GpIbalpha and GpIbbeta regulate 14-3-3zeta binding to GpIb/IX/V. Blood (2000) 0.90
Cytoplasmic truncation of glycoprotein Ib alpha weakens its interaction with von Willebrand factor and impairs cell adhesion. Biochemistry (2003) 0.89
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Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation. Blood (2011) 2.27
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Evidence for activation of tissue factor by an allosteric disulfide bond. Biochemistry (2006) 1.99
A molecular switch that controls cell spreading and retraction. J Cell Biol (2007) 1.93
A directional switch of integrin signalling and a new anti-thrombotic strategy. Nature (2013) 1.92
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High shear-dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIbα-filamin interaction. Blood (2010) 1.75
Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathway. J Immunol (2009) 1.70
Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases. J Biol Chem (2003) 1.63
A stimulatory role for cGMP-dependent protein kinase in platelet activation. Cell (2003) 1.54
Hearing evaluation of intratympanic methylprednisolone perfusion for refractory sudden sensorineural hearing loss. Otolaryngol Head Neck Surg (2010) 1.49
The dimeric versus monomeric status of 14-3-3zeta is controlled by phosphorylation of Ser58 at the dimer interface. J Biol Chem (2003) 1.49
Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members. Blood (2005) 1.47
Two distinct roles of mitogen-activated protein kinases in platelets and a novel Rac1-MAPK-dependent integrin outside-in retractile signaling pathway. Blood (2008) 1.47
Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3. Blood (2005) 1.44
Coagulation-induced shedding of platelet glycoprotein VI mediated by factor Xa. Blood (2011) 1.44
Association of Fyn and Lyn with the proline-rich domain of glycoprotein VI regulates intracellular signaling. J Biol Chem (2002) 1.39
G protein-dependent basal and evoked endothelial cell vWF secretion. Blood (2013) 1.39
IP-10 induces dissociation of newly formed blood vessels. J Cell Sci (2009) 1.38
A phosphoinositide 3-kinase-AKT-nitric oxide-cGMP signaling pathway in stimulating platelet secretion and aggregation. J Biol Chem (2006) 1.38
Delayed and deficient dermal maturation in mice lacking the CXCR3 ELR-negative CXC chemokine receptor. Am J Pathol (2007) 1.38
P-selectin anchors newly released ultralarge von Willebrand factor multimers to the endothelial cell surface. Blood (2003) 1.34
Critical roles for the COOH-terminal NITY and RGT sequences of the integrin beta3 cytoplasmic domain in inside-out and outside-in signaling. J Cell Biol (2003) 1.34
The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activation. Blood (2007) 1.33
Activation of dopamine D1-like receptors in nucleus accumbens is critical for the acquisition, but not the expression, of nutrient-conditioned flavor preferences in rats. Eur J Neurosci (2008) 1.31
Bruton tyrosine kinase is essential for botrocetin/VWF-induced signaling and GPIb-dependent thrombus formation in vivo. Blood (2006) 1.22
Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an alphaIIbbeta3- and aggregation-independent manner. Blood (2005) 1.21
Inside-out, outside-in, and inside-outside-in: G protein signaling in integrin-mediated cell adhesion, spreading, and retraction. Curr Opin Cell Biol (2012) 1.21
Tyrosine phosphorylation of the integrin beta 3 subunit regulates beta 3 cleavage by calpain. J Biol Chem (2006) 1.20
An important role for Akt3 in platelet activation and thrombosis. Blood (2011) 1.19
Stimulatory roles of nitric-oxide synthase 3 and guanylyl cyclase in platelet activation. J Biol Chem (2005) 1.16
Transforming growth factor beta suppresses human telomerase reverse transcriptase (hTERT) by Smad3 interactions with c-Myc and the hTERT gene. J Biol Chem (2006) 1.12
Antioxidant treatment reduces blast-induced cochlear damage and hearing loss. Hear Res (2012) 1.12
Heat-shock protein gp96/grp94 is an essential chaperone for the platelet glycoprotein Ib-IX-V complex. Blood (2011) 1.12
Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway. Blood (2008) 1.11
On the roles of cGMP and glycoprotein Ib in platelet activation. Blood (2004) 1.10
Interaction between von Willebrand factor and glycoprotein Ib activates Src kinase in human platelets: role of phosphoinositide 3-kinase. Blood (2002) 1.09
Regulation of glycoprotein Ib-IX-von Willebrand factor interaction by cAMP-dependent protein kinase-mediated phosphorylation at Ser 166 of glycoprotein Ib(beta). J Biol Chem (2002) 1.09
Anti-beta2-glycoprotein I antibodies in complex with beta2-glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib-IX-V. Arthritis Rheum (2006) 1.09
Morphological and functional alterations of the cochlea in apolipoprotein E gene deficient mice. Hear Res (2005) 1.09
Lack of CXC chemokine receptor 3 signaling leads to hypertrophic and hypercellular scarring. Am J Pathol (2010) 1.07
Dual ITAM-mediated proteolytic pathways for irreversible inactivation of platelet receptors: de-ITAM-izing FcgammaRIIa. Blood (2007) 1.06
cDNA cloning and characterization of a novel gene encoding the MLF1-interacting protein MLF1IP. Oncogene (2004) 1.06
A platelet secretion pathway mediated by cGMP-dependent protein kinase. J Biol Chem (2004) 1.05
Neutrophil AKT2 regulates heterotypic cell-cell interactions during vascular inflammation. J Clin Invest (2014) 1.05
Regulation of platelet membrane levels of glycoprotein VI by a platelet-derived metalloproteinase. Blood (2004) 1.04
Leucine-rich repeats 2-4 (Leu60-Glu128) of platelet glycoprotein Ibalpha regulate shear-dependent cell adhesion to von Willebrand factor. J Biol Chem (2006) 1.03
RGS3 interacts with 14-3-3 via the N-terminal region distinct from the RGS (regulator of G-protein signalling) domain. Biochem J (2002) 1.01
Bernard-Soulier syndrome. Haematologica (2011) 1.00
Platelet adhesion: a game of catch and release. J Clin Invest (2008) 1.00
An important role of the SRC family kinase Lyn in stimulating platelet granule secretion. J Biol Chem (2010) 1.00
Identification of a novel 14-3-3zeta binding site within the cytoplasmic tail of platelet glycoprotein Ibalpha. Blood (2004) 0.99
Glycoprotein VI is associated with GPIb-IX-V on the membrane of resting and activated platelets. Thromb Haemost (2005) 0.98
Consistent up-regulation of Stat3 Independently of Jak2 mutations in a new murine model of essential thrombocythemia. Cancer Res (2009) 0.98
Regulation of leukocyte degranulation by cGMP-dependent protein kinase and phosphoinositide 3-kinase: potential roles in phosphorylation of target membrane SNARE complex proteins in rat mast cells. J Immunol (2007) 0.97
The LFA-1-associated molecule PTA-1 (CD226) on T cells forms a dynamic molecular complex with protein 4.1G and human discs large. J Biol Chem (2004) 0.96
Angiotensin II-inducible platelet-derived growth factor-D transcription requires specific Ser/Thr residues in the second zinc finger region of Sp1. Circ Res (2008) 0.95
A critical role for Lyn kinase in strengthening endothelial integrity and barrier function. Blood (2013) 0.95
Antioxidants reduce cellular and functional changes induced by intense noise in the inner ear and cochlear nucleus. J Assoc Res Otolaryngol (2014) 0.93
Matrix control of scarring. Cell Mol Life Sci (2011) 0.93
Delineation of the region in the glycoprotein VI tail required for association with the Fc receptor gamma-chain. J Biol Chem (2003) 0.93
Platelet receptor proteolysis: a mechanism for downregulating platelet reactivity. Arterioscler Thromb Vasc Biol (2007) 0.92
The role of Rac1 in glycoprotein Ib-IX-mediated signal transduction and integrin activation. Arterioscler Thromb Vasc Biol (2012) 0.92
Antihemostatic activity of human granzyme B mediated by cleavage of von Willebrand factor. J Biol Chem (2008) 0.92
Signaling-mediated functional activation of inducible nitric-oxide synthase and its role in stimulating platelet activation. J Biol Chem (2008) 0.92
Constitutive dimerization of glycoprotein VI (GPVI) in resting platelets is essential for binding to collagen and activation in flowing blood. J Biol Chem (2012) 0.92
ADP-stimulated activation of Akt during integrin outside-in signaling promotes platelet spreading by inhibiting glycogen synthase kinase-3β. Arterioscler Thromb Vasc Biol (2012) 0.91
Role for platelet glycoprotein Ib-IX and effects of its inhibition in endotoxemia-induced thrombosis, thrombocytopenia, and mortality. Arterioscler Thromb Vasc Biol (2013) 0.89
Platelet receptor redox regulation. Platelets (2008) 0.88
The cryptome: a subset of the proteome, comprising cryptic peptides with distinct bioactivities. Drug Discov Today (2006) 0.88
LIM kinase-1 selectively promotes glycoprotein Ib-IX-mediated TXA2 synthesis, platelet activation, and thrombosis. Blood (2013) 0.88
Tetrahydroxystilbene glucoside improves the learning and memory of amyloid-β(₁₋₄₂)-injected rats and may be connected to synaptic changes in the hippocampus. Can J Physiol Pharmacol (2012) 0.87
Interaction of calmodulin with the cytoplasmic domain of platelet glycoprotein VI. Blood (2002) 0.87
Pathologic shear triggers shedding of vascular receptors: a novel mechanism for down-regulation of platelet glycoprotein VI in stenosed coronary vessels. Blood (2012) 0.87
SHIP-2 forms a tetrameric complex with filamin, actin, and GPIb-IX-V: localization of SHIP-2 to the activated platelet actin cytoskeleton. Blood (2003) 0.86
Transmembrane and trans-subunit regulation of ectodomain shedding of platelet glycoprotein Ibalpha. J Biol Chem (2010) 0.86
Impaired stria vascularis in the inner ear of apolipoprotein E gene knockout mice. ORL J Otorhinolaryngol Relat Spec (2008) 0.86
Platelet interactions in thrombosis. IUBMB Life (2004) 0.86
Effects of delayed and extended antioxidant treatment on acute acoustic trauma. Free Radic Res (2011) 0.85
Soluble glycoprotein VI is raised in the plasma of patients with acute ischemic stroke. Stroke (2010) 0.85
Opposing effects of platelet-activating factor and lyso-platelet-activating factor on neutrophil and platelet activation. Mol Pharmacol (2008) 0.84
Binding of von Willebrand factor to the small proteoglycan decorin. FEBS Lett (2004) 0.84
Ligand binding rapidly induces disulfide-dependent dimerization of glycoprotein VI on the platelet plasma membrane. J Biol Chem (2007) 0.84
Role of calmodulin in platelet receptor function. Curr Med Chem Cardiovasc Hematol Agents (2005) 0.84
Snake venom probes of platelet adhesion receptors and their ligands. Toxicon (2005) 0.83
Anti-glycoprotein VI monoclonal antibodies directly aggregate platelets independently of FcgammaRIIa and induce GPVI ectodomain shedding. Platelets (2009) 0.83
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Effects of simvastatin on plasma lipoproteins and hearing loss in apolipoprotein E gene-deficient mice. ORL J Otorhinolaryngol Relat Spec (2009) 0.82