Published in Brain Res Mol Brain Res on February 20, 2003
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Genetic variation in SCN10A influences cardiac conduction. Nat Genet (2010) 2.30
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Novel isoforms of the sodium channels Nav1.8 and Nav1.5 are produced by a conserved mechanism in mouse and rat. J Biol Chem (2004) 1.04
Dissecting the role of sodium currents in visceral sensory neurons in a model of chronic hyperexcitability using Nav1.8 and Nav1.9 null mice. J Physiol (2006) 1.01
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Exon 11 skipping of SCN10A coding for voltage-gated sodium channels in dorsal root ganglia. Channels (Austin) (2014) 0.75
An SCN9A channelopathy causes congenital inability to experience pain. Nature (2006) 7.01
Wait-and-see prescription for the treatment of acute otitis media: a randomized controlled trial. JAMA (2006) 4.18
SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes. Neuron (2006) 3.96
The cell and molecular basis of mechanical, cold, and inflammatory pain. Science (2008) 3.46
A gain-of-function mutation in TRPA1 causes familial episodic pain syndrome. Neuron (2010) 3.31
Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain. Proc Natl Acad Sci U S A (2004) 3.07
Parallel "pain" pathways arise from subpopulations of primary afferent nociceptor. Neuron (2005) 3.03
Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures. Nature (2007) 2.71
The TTX-resistant sodium channel Nav1.8 (SNS/PN3): expression and correlation with membrane properties in rat nociceptive primary afferent neurons. J Physiol (2003) 2.59
Acid-sensing ion channels ASIC2 and ASIC3 do not contribute to mechanically activated currents in mammalian sensory neurones. J Physiol (2004) 2.48
Distinct mechanosensitive properties of capsaicin-sensitive and -insensitive sensory neurons. J Neurosci (2002) 2.40
Nav1.8 expression is not restricted to nociceptors in mouse peripheral nervous system. Pain (2012) 2.34
Loss-of-function mutations in sodium channel Nav1.7 cause anosmia. Nature (2011) 2.31
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The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons. Nat Neurosci (2012) 2.28
VGLUT2-dependent sensory neurons in the TRPV1 population regulate pain and itch. Neuron (2010) 2.22
Human visceral afferent recordings: preliminary report. Gut (2010) 2.15
Intense isolectin-B4 binding in rat dorsal root ganglion neurons distinguishes C-fiber nociceptors with broad action potentials and high Nav1.9 expression. J Neurosci (2006) 2.05
Voltage-gated sodium channels and pain pathways. J Neurobiol (2004) 1.97
Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia. Pain (2011) 1.90
Annexin II light chain regulates sensory neuron-specific sodium channel expression. Nature (2002) 1.88
Neuropathic pain develops normally in mice lacking both Na(v)1.7 and Na(v)1.8. Mol Pain (2005) 1.86
Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons. Nat Commun (2012) 1.72
Nociceptor-specific gene deletion using heterozygous NaV1.8-Cre recombinase mice. Pain (2005) 1.72
GTP-induced tetrodotoxin-resistant Na+ current regulates excitability in mouse and rat small diameter sensory neurones. J Physiol (2003) 1.62
Remote optogenetic activation and sensitization of pain pathways in freely moving mice. J Neurosci (2013) 1.62
Neurological perspectives on voltage-gated sodium channels. Brain (2012) 1.62
The tetrodotoxin-resistant Na+ channel Nav1.8 is essential for the expression of spontaneous activity in damaged sensory axons of mice. J Physiol (2003) 1.54
Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron (2008) 1.52
GTP up-regulated persistent Na+ current and enhanced nociceptor excitability require NaV1.9. J Physiol (2007) 1.49
Deficits in visceral pain and referred hyperalgesia in Nav1.8 (SNS/PN3)-null mice. J Neurosci (2002) 1.48
High-threshold mechanosensitive ion channels blocked by a novel conopeptide mediate pressure-evoked pain. PLoS One (2007) 1.38
Modulation of sensory neuron mechanotransduction by PKC- and nerve growth factor-dependent pathways. Proc Natl Acad Sci U S A (2006) 1.38
Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis. Proc Natl Acad Sci U S A (2013) 1.34
Pain as a channelopathy. J Clin Invest (2010) 1.33
Small RNAs control sodium channel expression, nociceptor excitability, and pain thresholds. J Neurosci (2010) 1.28
trkA is expressed in nociceptive neurons and influences electrophysiological properties via Nav1.8 expression in rapidly conducting nociceptors. J Neurosci (2005) 1.24
Nociceptor-derived brain-derived neurotrophic factor regulates acute and inflammatory but not neuropathic pain. Mol Cell Neurosci (2006) 1.24
The roles of sodium channels in nociception: implications for mechanisms of neuropathic pain. Pain Med (2011) 1.23
Pain genes. PLoS Genet (2008) 1.23
Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice. Mol Pain (2006) 1.21
Increasingly irritable and close to tears: TRPA1 in inflammatory pain. Cell (2006) 1.18
Excitability parameters and sensitivity to anemone toxin ATX-II in rat small diameter primary sensory neurones discriminated by Griffonia simplicifolia isolectin IB4. J Physiol (2009) 1.16
Genetic tracing of Nav1.8-expressing vagal afferents in the mouse. J Comp Neurol (2011) 1.16
TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells. Open Biol (2012) 1.16
GRK2: a novel cell-specific regulator of severity and duration of inflammatory pain. J Neurosci (2010) 1.15
Ciguatoxins activate specific cold pain pathways to elicit burning pain from cooling. EMBO J (2012) 1.15
FM1-43 is a permeant blocker of mechanosensitive ion channels in sensory neurons and inhibits behavioural responses to mechanical stimuli. Mol Pain (2007) 1.12
Comparison of dorsal root ganglion gene expression in rat models of traumatic and HIV-associated neuropathic pain. Eur J Pain (2008) 1.12
Deletion of annexin 2 light chain p11 in nociceptors causes deficits in somatosensory coding and pain behavior. J Neurosci (2006) 1.11
Kinetic properties of mechanically activated currents in spinal sensory neurons. J Physiol (2009) 1.10
Pain channelopathies. J Physiol (2010) 1.09
Annexin II light chain p11 promotes functional expression of acid-sensing ion channel ASIC1a. J Biol Chem (2005) 1.08
Low nociceptor GRK2 prolongs prostaglandin E2 hyperalgesia via biased cAMP signaling to Epac/Rap1, protein kinase Cepsilon, and MEK/ERK. J Neurosci (2010) 1.06
Sensory neuron voltage-gated sodium channels as analgesic drug targets. Curr Opin Neurobiol (2008) 1.06
Extensive co-localization and heteromultimer formation of the vanilloid receptor-like protein TRPV2 and the capsaicin receptor TRPV1 in the adult rat cerebral cortex. Eur J Neurosci (2005) 1.06
Electrophysiological characterization of the tetrodotoxin-resistant Na+ channel, Na(v)1.9, in mouse dorsal root ganglion neurons. Pflugers Arch (2004) 1.04
Alternative splicing of Nav1.5: an electrophysiological comparison of 'neonatal' and 'adult' isoforms and critical involvement of a lysine residue. J Cell Physiol (2008) 1.03
RET signaling is required for survival and normal function of nonpeptidergic nociceptors. J Neurosci (2010) 1.03
Nerve growth factor and pain. N Engl J Med (2010) 1.03
Protein-protein interactions involving voltage-gated sodium channels: Post-translational regulation, intracellular trafficking and functional expression. Int J Biochem Cell Biol (2009) 1.00
No pain, more gain. Nat Genet (2013) 1.00
Sensory axon-derived neuregulin-1 is required for axoglial signaling and normal sensory function but not for long-term axon maintenance. J Neurosci (2009) 1.00
Identification of binding domains in the sodium channel Na(V)1.8 intracellular N-terminal region and annexin II light chain p11. FEBS Lett (2004) 1.00
Recovery of deficient homologous recombination in Brca2-depleted mouse cells by wild-type Rad51 expression. DNA Repair (Amst) (2008) 1.00
A clinically relevant rodent model of the HIV antiretroviral drug stavudine induced painful peripheral neuropathy. Pain (2013) 1.00
Proteomic profiling of neuromas reveals alterations in protein composition and local protein synthesis in hyper-excitable nerves. Mol Pain (2008) 0.98
Association between tetrodotoxin resistant channels and lipid rafts regulates sensory neuron excitability. PLoS One (2012) 0.98
The mechanosensitive cell line ND-C does not express functional thermoTRP channels. Neuropharmacology (2009) 0.95
Identification of a receptor for neuropeptide VGF and its role in neuropathic pain. J Biol Chem (2013) 0.94
Temporal control of gene deletion in sensory ganglia using a tamoxifen-inducible Advillin-Cre-ERT2 recombinase mouse. Mol Pain (2011) 0.94
A sensory subpopulation depends on vesicular glutamate transporter 2 for mechanical pain, and together with substance P, inflammatory pain. Proc Natl Acad Sci U S A (2011) 0.94
20-Hydroxyeicosatetraenoic acid (20-HETE) is a novel activator of transient receptor potential vanilloid 1 (TRPV1) channel. J Biol Chem (2012) 0.92
Regulation of ASIC activity by ASIC4--new insights into ASIC channel function revealed by a yeast two-hybrid assay. Eur J Neurosci (2008) 0.92
Roles of ASIC3, TRPV1, and NaV1.8 in the transition from acute to chronic pain in a mouse model of fibromyalgia. Mol Pain (2014) 0.92
Sodium channels and mammalian sensory mechanotransduction. Mol Pain (2012) 0.91
Transient receptor potential channels and mechanosensation. Annu Rev Neurosci (2013) 0.91
Ion channel activities implicated in pathological pain. Novartis Found Symp (2004) 0.91
A peripheral nervous system actin-binding protein regulates neurite outgrowth. Eur J Neurosci (2002) 0.90
Mechanical allodynia. Pflugers Arch (2014) 0.90
A multi PDZ-domain protein Pdzd2 contributes to functional expression of sensory neuron-specific sodium channel Na(V)1.8. Mol Cell Neurosci (2009) 0.89