Published in J Am Chem Soc on March 05, 2003
Identification of cross-linked peptides from large sequence databases. Nat Methods (2008) 4.03
Probing native protein structures by chemical cross-linking, mass spectrometry, and bioinformatics. Mol Cell Proteomics (2010) 3.44
Expanding the chemical cross-linking toolbox by the use of multiple proteases and enrichment by size exclusion chromatography. Mol Cell Proteomics (2012) 1.77
Development of a novel cross-linking strategy for fast and accurate identification of cross-linked peptides of protein complexes. Mol Cell Proteomics (2010) 1.61
Chemistry of periodate-mediated cross-linking of 3,4-dihydroxylphenylalanine-containing molecules to proteins. J Am Chem Soc (2006) 1.60
Identification of protein-protein interactions and topologies in living cells with chemical cross-linking and mass spectrometry. Mol Cell Proteomics (2008) 1.58
Unraveling the interface of signal recognition particle and its receptor by using chemical cross-linking and tandem mass spectrometry. Proc Natl Acad Sci U S A (2004) 1.30
Integrative structure modeling of macromolecular assemblies from proteomics data. Mol Cell Proteomics (2010) 1.28
Finding chimeras: a bioinformatics strategy for identification of cross-linked peptides. Mol Cell Proteomics (2009) 1.27
Quantitative encoding of the effect of a partial agonist on individual opioid receptors by multisite phosphorylation and threshold detection. Sci Signal (2011) 1.25
Identification of cross-linked peptides after click-based enrichment using sequential collision-induced dissociation and electron transfer dissociation tandem mass spectrometry. Anal Chem (2009) 1.20
A new cross-linking strategy: protein interaction reporter (PIR) technology for protein-protein interaction studies. Mol Biosyst (2010) 1.14
CLPM: a cross-linked peptide mapping algorithm for mass spectrometric analysis. BMC Bioinformatics (2005) 1.08
Mass spectrometry analysis of HIV-1 Vif reveals an increase in ordered structure upon oligomerization in regions necessary for viral infectivity. Proteins (2007) 1.04
Selective enrichment and identification of azide-tagged cross-linked peptides using chemical ligation and mass spectrometry. J Am Soc Mass Spectrom (2010) 1.01
Elucidating the higher-order structure of biopolymers by structural probing and mass spectrometry: MS3D. J Mass Spectrom (2010) 1.00
Synthesis of biotin-tagged chemical cross-linkers and their applications for mass spectrometry. Rapid Commun Mass Spectrom (2009) 0.99
Incorporation of paramagnetic, fluorescent and PET/SPECT contrast agents into liposomes for multimodal imaging. Biomaterials (2012) 0.96
A simple and reliable approach to docking protein-protein complexes from very sparse NOE-derived intermolecular distance restraints. J Biomol NMR (2006) 0.96
Xlink-identifier: an automated data analysis platform for confident identifications of chemically cross-linked peptides using tandem mass spectrometry. J Proteome Res (2011) 0.96
Free energies of protein-protein association determined by electrospray ionization mass spectrometry correlate accurately with values obtained by solution methods. Protein Sci (2006) 0.93
Nonprotein based enrichment method to analyze peptide cross-linking in protein complexes. Anal Chem (2009) 0.91
Covalent capture of phospho-dependent protein oligomerization by site-specific incorporation of a diazirine photo-cross-linker. J Am Chem Soc (2007) 0.91
Probabilistic cross-link analysis and experiment planning for high-throughput elucidation of protein structure. Protein Sci (2004) 0.90
Quaternary diamines as mass spectrometry cleavable crosslinkers for protein interactions. J Am Soc Mass Spectrom (2011) 0.89
Identifying an interaction site between MutH and the C-terminal domain of MutL by crosslinking, affinity purification, chemical coding and mass spectrometry. Nucleic Acids Res (2006) 0.89
Investigation of stable and transient protein-protein interactions: Past, present, and future. Proteomics (2013) 0.88
Trifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational states. Elife (2016) 0.88
The diverse and expanding role of mass spectrometry in structural and molecular biology. EMBO J (2016) 0.87
Designer reagents for mass spectrometry-based proteomics: clickable cross-linkers for elucidation of protein structures and interactions. Anal Chem (2012) 0.87
A high-resolution interaction map of three transcriptional activation domains with a key coactivator from photo-cross-linking and multiplexed mass spectrometry. Angew Chem Int Ed Engl (2009) 0.86
Deciphering structure and topology of conserved COG2042 orphan proteins. BMC Struct Biol (2005) 0.79
Evaluating protein interactions through cross-linking mass spectrometry. Nat Methods (2012) 0.79
Revealing Higher Order Protein Structure Using Mass Spectrometry. J Am Soc Mass Spectrom (2016) 0.78
Photocleavable peptide-oligonucleotide conjugates for protein kinase assays by MALDI-TOF MS. Mol Biosyst (2012) 0.78
Novel octavalent cross-linker displays efficient trapping of protein-protein interactions. Chem Commun (Camb) (2007) 0.75
A reinforced composite structure composed of polydiacetylene assemblies deposited on polystyrene microspheres and its application to H5N1 virus detection. Int J Nanomedicine (2013) 0.75
Mass spectrometry tools for analysis of intermolecular interactions. Methods Mol Biol (2012) 0.75
Induction of Antibodies Directed Against Branched Core O-Mannosyl Glycopeptides - Selectivity Complimentary to the ConA Lectin. Chemistry (2017) 0.75
X-ray structure of a voltage-dependent K+ channel. Nature (2003) 14.50
A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature (2006) 10.73
Crystal structure and mechanism of a calcium-gated potassium channel. Nature (2002) 10.03
X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity. Nature (2002) 9.96
The open pore conformation of potassium channels. Nature (2002) 9.09
Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding. Science (2011) 9.00
The molecular architecture of the nuclear pore complex. Nature (2007) 6.93
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nat Cell Biol (2009) 6.69
Proteomic analysis of the mammalian nuclear pore complex. J Cell Biol (2002) 6.38
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma. Science (2013) 6.29
Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Cell (2005) 6.12
Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement. Nat Immunol (2002) 5.67
Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB. Nature (2010) 5.23
Determining the architectures of macromolecular assemblies. Nature (2007) 4.94
Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin. Proc Natl Acad Sci U S A (2009) 4.88
The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2. Mol Cell (2002) 3.99
Protein production and purification. Nat Methods (2008) 3.97
Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration. Proc Natl Acad Sci U S A (2007) 3.92
Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs. Mol Cell (2006) 3.87
RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Cell (2009) 3.82
Crystal structure of the MazE/MazF complex: molecular bases of antidote-toxin recognition. Mol Cell (2003) 3.66
Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation. Nature (2008) 3.55
Methylation of a histone mimic within the histone methyltransferase G9a regulates protein complex assembly. Mol Cell (2007) 3.51
X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by proto-oncogenic transcription factors. Cell (2003) 3.37
Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator. EMBO J (2003) 3.35
Crystal structure of a Kir3.1-prokaryotic Kir channel chimera. EMBO J (2007) 3.31
ABI5 acts downstream of ABI3 to execute an ABA-dependent growth arrest during germination. Plant J (2002) 3.28
Induction of autophagy in axonal dystrophy and degeneration. J Neurosci (2006) 3.28
POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex. Genes Dev (2004) 3.25
Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching. Science (2013) 3.02
Fluorescent proteins as proteomic probes. Mol Cell Proteomics (2005) 2.98
ModBase, a database of annotated comparative protein structure models, and associated resources. Nucleic Acids Res (2010) 2.96
Components of coated vesicles and nuclear pore complexes share a common molecular architecture. PLoS Biol (2004) 2.90
Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions. Cell (2011) 2.68
Virtual gating and nuclear transport: the hole picture. Trends Cell Biol (2003) 2.68
Protein ligation: an enabling technology for the biophysical analysis of proteins. Nat Methods (2006) 2.60
Comprehensive analysis of diverse ribonucleoprotein complexes. Nat Methods (2007) 2.55
Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins. J Mol Biol (2002) 2.53
Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini. Proc Natl Acad Sci U S A (2007) 2.43
Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction. Nat Chem Biol (2011) 2.39
TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres. J Biol Chem (2004) 2.36
Simple fold composition and modular architecture of the nuclear pore complex. Proc Natl Acad Sci U S A (2006) 2.35
A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae. Mol Cell Proteomics (2011) 2.34
Outcome of a workshop on archiving structural models of biological macromolecules. Structure (2006) 2.32
Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly. Dev Cell (2007) 2.25
Chromatin-bound Xenopus Dppa2 shapes the nucleus by locally inhibiting microtubule assembly. Dev Cell (2013) 2.09
RADARS, a bioinformatics solution that automates proteome mass spectral analysis, optimises protein identification, and archives data in a relational database. Proteomics (2002) 2.08
Outcome of a workshop on applications of protein models in biomedical research. Structure (2009) 2.05
Activation of protein splicing with light in yeast. Nat Methods (2008) 2.02
Tracking and elucidating alphavirus-host protein interactions. J Biol Chem (2006) 2.01
Ion selectivity in a semisynthetic K+ channel locked in the conductive conformation. Science (2006) 2.00
Two structurally atypical HEAT domains in the C-terminal portion of human eIF4G support binding to eIF4A and Mnk1. Structure (2006) 1.99
Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration. Proc Natl Acad Sci U S A (2005) 1.97
Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation. Proc Natl Acad Sci U S A (2006) 1.95
Proteomic and genomic characterization of chromatin complexes at a boundary. J Cell Biol (2005) 1.92
Structural genomics: a pipeline for providing structures for the biologist. Protein Sci (2002) 1.91
E protein silencing by the leukemogenic AML1-ETO fusion protein. Science (2004) 1.89
X-ray structure of a Rex-family repressor/NADH complex insights into the mechanism of redox sensing. Structure (2005) 1.89
Artificial nanopores that mimic the transport selectivity of the nuclear pore complex. Nature (2008) 1.89
I-DIRT, a general method for distinguishing between specific and nonspecific protein interactions. J Proteome Res (2005) 1.87
MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription. Mol Cell (2005) 1.85
Human cytomegalovirus protein UL38 inhibits host cell stress responses by antagonizing the tuberous sclerosis protein complex. Cell Host Microbe (2008) 1.85
Key determinants of receptor activation in the agr autoinducing peptides of Staphylococcus aureus. Biochemistry (2002) 1.84
Disulfide-directed histone ubiquitylation reveals plasticity in hDot1L activation. Nat Chem Biol (2010) 1.80
Regulation of class switch recombination and somatic mutation by AID phosphorylation. J Exp Med (2008) 1.78
Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein. J Virol (2010) 1.78
Simple kinetic relationships and nonspecific competition govern nuclear import rates in vivo. J Cell Biol (2006) 1.78
The cholesterol-regulated StarD4 gene encodes a StAR-related lipid transfer protein with two closely related homologues, StarD5 and StarD6. Proc Natl Acad Sci U S A (2002) 1.76
Identification of SMARCAL1 as a component of the DNA damage response. J Biol Chem (2009) 1.74
Evidence for a shared nuclear pore complex architecture that is conserved from the last common eukaryotic ancestor. Mol Cell Proteomics (2009) 1.74
Post-translational enzyme activation in an animal via optimized conditional protein splicing. Nat Chem Biol (2006) 1.71
SGX393 inhibits the CML mutant Bcr-AblT315I and preempts in vitro resistance when combined with nilotinib or dasatinib. Proc Natl Acad Sci U S A (2008) 1.71
Long range allosteric control of cytoplasmic dynein ATPase activity by the stalk and C-terminal domains. J Biol Chem (2005) 1.68
Ku80 removal from DNA through double strand break-induced ubiquitylation. J Cell Biol (2008) 1.64
Crystal structure of shikimate 5-dehydrogenase (SDH) bound to NADP: insights into function and evolution. Structure (2003) 1.64
Uncoupling of initiation factor eIF5B/IF2 GTPase and translational activities by mutations that lower ribosome affinity. Cell (2002) 1.64
Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex. Proc Natl Acad Sci U S A (2007) 1.64
Detection of secreted peptides by using hypothesis-driven multistage mass spectrometry. Proc Natl Acad Sci U S A (2003) 1.63
The mobile nucleoporin Nup2p and chromatin-bound Prp20p function in endogenous NPC-mediated transcriptional control. J Cell Biol (2005) 1.59
Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1. J Biol Chem (2005) 1.57
Targeted proteomic study of the cyclin-Cdk module. Mol Cell (2004) 1.56
Structure of microcin J25, a peptide inhibitor of bacterial RNA polymerase, is a lassoed tail. J Am Chem Soc (2003) 1.56
A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase. J Biol Chem (2004) 1.55
Synergistic functions of SII and p300 in productive activator-dependent transcription of chromatin templates. Cell (2006) 1.54
A semisynthetic Eph receptor tyrosine kinase provides insight into ligand-induced kinase activation. Chem Biol (2011) 1.54
Analysis of protein phosphorylation by hypothesis-driven multiple-stage mass spectrometry. Anal Chem (2004) 1.52
RNA ligase RtcB splices 3'-phosphate and 5'-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3')pp(5')G intermediates. Proc Natl Acad Sci U S A (2012) 1.51
Semisynthesis of a segmental isotopically labeled protein splicing precursor: NMR evidence for an unusual peptide bond at the N-extein-intein junction. Proc Natl Acad Sci U S A (2004) 1.51
Carbon dioxide-induced anesthesia results in a rapid increase in plasma levels of vasopressin. Endocrinology (2009) 1.49
Improved beta-elimination-based affinity purification strategy for enrichment of phosphopeptides. Anal Chem (2003) 1.48
PET imaging of leptin biodistribution and metabolism in rodents and primates. Cell Metab (2009) 1.47
Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4) containing a StAR-related lipid transfer domain. Proc Natl Acad Sci U S A (2002) 1.47
Conditional protein splicing: a new tool to control protein structure and function in vitro and in vivo. J Am Chem Soc (2003) 1.46
GINS motion reveals replication fork progression is remarkably uniform throughout the yeast genome. Mol Syst Biol (2010) 1.45
Chromatin as an expansive canvas for chemical biology. Nat Chem Biol (2012) 1.45
Structural basis for autoinhibition and mutational activation of eukaryotic initiation factor 2alpha protein kinase GCN2. J Biol Chem (2005) 1.44
Molecular mechanisms of agr quorum sensing in virulent staphylococci. Chembiochem (2007) 1.44
Structure-function mapping of a heptameric module in the nuclear pore complex. J Cell Biol (2012) 1.44
Genetically encoded 1,2-aminothiols facilitate rapid and site-specific protein labeling via a bio-orthogonal cyanobenzothiazole condensation. J Am Chem Soc (2011) 1.42