Published in Hypertension on May 12, 2003
Renal Transplant Injury and the Renin-Angiotensin System in Kids (RETASK) (RETASK) | NCT03317925
Uric acid and cardiovascular risk. N Engl J Med (2008) 12.20
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Uric acid and inflammatory markers. Eur Heart J (2006) 2.81
Ketohexokinase-dependent metabolism of fructose induces proinflammatory mediators in proximal tubular cells. J Am Soc Nephrol (2009) 2.70
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Uric acid transport and disease. J Clin Invest (2010) 2.33
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Hyperuricemia and risk of stroke: a systematic review and meta-analysis. Arthritis Rheum (2009) 2.07
Hyperuricemia as a mediator of the proinflammatory endocrine imbalance in the adipose tissue in a murine model of the metabolic syndrome. Diabetes (2011) 1.82
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High-normal serum uric acid is associated with impaired glomerular filtration rate in nonproteinuric patients with type 1 diabetes. Clin J Am Soc Nephrol (2008) 1.74
Effect of lowering uric acid on renal disease in the type 2 diabetic db/db mice. Am J Physiol Renal Physiol (2009) 1.69
Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia. Am J Physiol Renal Physiol (2008) 1.68
Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructose-dependent and -independent fatty liver. J Biol Chem (2012) 1.67
Systemic inflammation, metabolic syndrome and progressive renal disease. Nephrol Dial Transplant (2009) 1.63
Longitudinal association between serum urate and subclinical atherosclerosis: the Coronary Artery Risk Development in Young Adults (CARDIA) study. J Intern Med (2013) 1.50
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Endogenous fructose production and fructokinase activation mediate renal injury in diabetic nephropathy. J Am Soc Nephrol (2014) 1.13
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Uric acid-induced endothelial dysfunction is associated with mitochondrial alterations and decreased intracellular ATP concentrations. Nephron Exp Nephrol (2012) 1.12
Serum uric acid is associated with carotid plaques: the National Heart, Lung, and Blood Institute Family Heart Study. J Rheumatol (2009) 1.11
Uric acid as a mediator of diabetic nephropathy. Semin Nephrol (2011) 1.11
Elevated serum uric acid is associated with high circulating inflammatory cytokines in the population-based Colaus study. PLoS One (2011) 1.11
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The relationship between hyperuricemia and the risk of contrast-induced acute kidney injury after percutaneous coronary intervention in patients with relatively normal serum creatinine. Clinics (Sao Paulo) (2013) 0.98
Uric acid is an independent risk factor for carotid atherosclerosis in a Japanese elderly population without metabolic syndrome. Cardiovasc Diabetol (2012) 0.95
Hyperuricemia causes pancreatic β-cell death and dysfunction through NF-κB signaling pathway. PLoS One (2013) 0.95
The planetary biology of ascorbate and uric acid and their relationship with the epidemic of obesity and cardiovascular disease. Med Hypotheses (2008) 0.94
Febuxostat, an inhibitor of xanthine oxidase, suppresses lipopolysaccharide-induced MCP-1 production via MAPK phosphatase-1-mediated inactivation of JNK. PLoS One (2013) 0.93
Synergistic effect of uricase blockade plus physiological amounts of fructose-glucose on glomerular hypertension and oxidative stress in rats. Am J Physiol Renal Physiol (2013) 0.93
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Uric acid promotes apoptosis in human proximal tubule cells by oxidative stress and the activation of NADPH oxidase NOX 4. PLoS One (2014) 0.91
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Serum uric acid is associated with high blood pressure in pediatric hemodialysis patients. Pediatr Nephrol (2011) 0.88
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Long-term effects of L- and N-type calcium channel blocker on uric acid levels and left atrial volume in hypertensive patients. Heart Vessels (2016) 0.85
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Relationship between Plasma Pentraxin-3, Neutrophil-to-Lymphocyte Ratio, and Atherosclerosis in Renal Transplant Patients. Cardiorenal Med (2012) 0.84
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Hyperuricemia and untreated gout are poor prognostic markers among those with a recent acute myocardial infarction. Arthritis Res Ther (2012) 0.83
Serum uric acid as an index of impaired renal function in congestive heart failure. J Geriatr Cardiol (2012) 0.83
Inflammation and pyroptosis mediate muscle expansion in an interleukin-1β (IL-1β)-dependent manner. J Biol Chem (2015) 0.82
Serum urate is not associated with coronary artery calcification: the NHLBI Family Heart Study. J Rheumatol (2010) 0.82
Mitochondria: a new therapeutic target in chronic kidney disease. Nutr Metab (Lond) (2015) 0.82
Vascular endothelial function is not related to serum uric acid in healthy adults. Am J Hypertens (2012) 0.82
EGF Receptor Inhibition Alleviates Hyperuricemic Nephropathy. J Am Soc Nephrol (2015) 0.82
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Comorbidities in patients with crystal diseases and hyperuricemia. Rheum Dis Clin North Am (2014) 0.81
Role of xanthine oxidoreductase in cardiac nitroso-redox imbalance. Front Biosci (Landmark Ed) (2009) 0.81
Various forms of tissue damage and danger signals following hematopoietic stem-cell transplantation. Front Immunol (2015) 0.81
Uric acid, hypertension, and chronic kidney disease among Alaska Eskimos: the Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) study. J Clin Hypertens (Greenwich) (2012) 0.81
Serum uric Acid level and diverse impacts on regional arterial stiffness and wave reflection. Iran J Public Health (2012) 0.80
Relationship between uric acid and subtle cognitive dysfunction in chronic kidney disease. Am J Nephrol (2011) 0.80
Hyperuricemia: A Biomarker of Renal Hemodynamic Impairment. Cardiorenal Med (2015) 0.80
The association between hyperuricemia and betel nut chewing in Taiwanese men: a cross-sectional study. BMC Public Health (2013) 0.80
Prevention of comorbidity and acute attack of gout by uric acid lowering therapy. J Korean Med Sci (2014) 0.80
Gout and Risk of Myocardial Infarction: A Systematic Review and Meta-Analysis of Cohort Studies. PLoS One (2015) 0.80
Association of Serum Uric Acid with Cardiovascular Disease in Taiwanese Patients with Primary Hypertension. Zhonghua Minguo Xin Zang Xue Hui Za Zhi (2015) 0.80
The Association between Serum Uric Acid Levels and the Prevalence of Vulnerable Atherosclerotic Carotid Plaque: A Cross-sectional Study. Sci Rep (2015) 0.79
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Serum uric acid levels and cerebral microbleeds in patients with acute ischemic stroke. PLoS One (2013) 0.77
Associations of the uric acid related genetic variants in SLC2A9 and ABCG2 loci with coronary heart disease risk. BMC Genet (2015) 0.77
Inhibition of Inducible Nitric Oxide Synthase Attenuates Monosodium Urate-induced Inflammation in Mice. Korean J Physiol Pharmacol (2011) 0.77
A cross-sectional analysis of the relationship between uric acid and coronary atherosclerosis in patients with suspected coronary artery disease in China. BMC Cardiovasc Disord (2014) 0.76
Longitudinal Association Between Serum Uric Acid and Arterial Stiffness: Results From the Baltimore Longitudinal Study of Aging. Hypertension (2016) 0.76
Relationship between Serum Uric Acid Concentration and Acute Kidney Injury after Coronary Artery Bypass Surgery. J Korean Med Sci (2015) 0.76
Opposite Expression of SPARC between the Liver and Pancreas in Streptozotocin-Induced Diabetic Rats. PLoS One (2015) 0.76
Uric acid level and erectile dysfunction in patients with coronary artery disease. J Sex Med (2013) 0.76
A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78
Uric acid and cardiovascular risk. N Engl J Med (2008) 12.20
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell (2004) 10.89
Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases. Am J Pathol (2003) 8.61
Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet (2003) 7.98
T-cell accumulation and regulated on activation, normal T cell expressed and secreted upregulation in adipose tissue in obesity. Circulation (2007) 6.23
Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways. Nat Med (2011) 6.21
Chronic dialysis and death among survivors of acute kidney injury requiring dialysis. JAMA (2009) 6.06
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Effect of allopurinol on blood pressure of adolescents with newly diagnosed essential hypertension: a randomized trial. JAMA (2008) 5.59
Is there a pathogenetic role for uric acid in hypertension and cardiovascular and renal disease? Hypertension (2003) 5.47
Hyperuricemia induces endothelial dysfunction. Kidney Int (2005) 5.36
Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease. Am J Clin Nutr (2007) 5.28
A causal role for uric acid in fructose-induced metabolic syndrome. Am J Physiol Renal Physiol (2005) 4.95
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Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis. Cell (2010) 4.01
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A role for uric acid in the progression of renal disease. J Am Soc Nephrol (2002) 3.77
Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease. Hepatology (2010) 3.73
Uric acid-induced C-reactive protein expression: implication on cell proliferation and nitric oxide production of human vascular cells. J Am Soc Nephrol (2005) 3.73
When laboratories report estimated glomerular filtration rates in addition to serum creatinines, nephrology consults increase. Kidney Int (2009) 3.70
A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer. Cell Stem Cell (2010) 3.43
Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism. Am J Physiol Renal Physiol (2002) 3.37
Fructose consumption as a risk factor for non-alcoholic fatty liver disease. J Hepatol (2008) 3.33
Evolving importance of kidney disease: from subspecialty to global health burden. Lancet (2013) 3.30
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Mirid bug outbreaks in multiple crops correlated with wide-scale adoption of Bt cotton in China. Science (2010) 3.09
Diabetic endothelial nitric oxide synthase knockout mice develop advanced diabetic nephropathy. J Am Soc Nephrol (2007) 3.08
An integrated physical and genetic map of the rice genome. Plant Cell (2002) 3.07
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TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29. J Am Soc Nephrol (2011) 2.78
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Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress. Am J Physiol Cell Physiol (2007) 2.71
Smad3-mediated upregulation of miR-21 promotes renal fibrosis. J Am Soc Nephrol (2011) 2.71
Ketohexokinase-dependent metabolism of fructose induces proinflammatory mediators in proximal tubular cells. J Am Soc Nephrol (2009) 2.70
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Essential role of Smad3 in angiotensin II-induced vascular fibrosis. Circ Res (2006) 2.59
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miR-192 mediates TGF-beta/Smad3-driven renal fibrosis. J Am Soc Nephrol (2010) 2.51
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STAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells. Blood (2010) 2.48
Urinary CD80 is elevated in minimal change disease but not in focal segmental glomerulosclerosis. Kidney Int (2010) 2.47
Uric acid, hominoid evolution, and the pathogenesis of salt-sensitivity. Hypertension (2002) 2.47
Nephrologist follow-up improves all-cause mortality of severe acute kidney injury survivors. Kidney Int (2013) 2.42
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Lamp-2a facilitates MHC class II presentation of cytoplasmic antigens. Immunity (2005) 2.40
Hyperuricemia in childhood primary hypertension. Hypertension (2003) 2.39
Smad3 mediates cardiac inflammation and fibrosis in angiotensin II-induced hypertensive cardiac remodeling. Hypertension (2010) 2.39
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CIITA-regulated plexin-A1 affects T-cell-dendritic cell interactions. Nat Immunol (2003) 2.13
14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition. Cancer Cell (2009) 2.09
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Knockdown of NOB1 expression by RNAi inhibits cellular proliferation and migration in human gliomas. Gene (2013) 2.03
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Mild hyperuricemia induces vasoconstriction and maintains glomerular hypertension in normal and remnant kidney rats. Kidney Int (2005) 2.02
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Fructose-induced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats. Am J Physiol Renal Physiol (2006) 1.94
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