Published in J Immunol on April 01, 2003
T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype. Blood (2006) 2.34
The transcription factor STAT3 is required for T helper 2 cell development. Immunity (2011) 2.03
Recurrent mutations of the STAT6 DNA binding domain in primary mediastinal B-cell lymphoma. Blood (2009) 1.92
Transcriptional regulation by STAT6. Immunol Res (2011) 1.81
Shp1 regulates T cell homeostasis by limiting IL-4 signals. J Exp Med (2013) 1.64
IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation. J Immunol (2010) 1.49
Increased Th2 activity and diminished skin barrier function cooperate in allergic skin inflammation. Eur J Immunol (2016) 1.42
The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation. Nat Immunol (2013) 1.26
Stat6 signaling suppresses VLA-4 expression by CD8+ T cells and limits their ability to infiltrate tumor lesions in vivo. J Immunol (2008) 1.01
Genome-wide approaches reveal functional interleukin-4-inducible STAT6 binding to the vascular cell adhesion molecule 1 promoter. Mol Cell Biol (2011) 1.00
Receptor crosstalk: reprogramming B cell receptor signalling to an alternate pathway results in expression and secretion of the autoimmunity-associated cytokine, osteopontin. J Intern Med (2009) 0.90
Constitutively active STAT6 predisposes toward a lymphoproliferative disorder. Blood (2007) 0.90
Wheezing and itching: The requirement for STAT proteins in allergic inflammation. JAKSTAT (2012) 0.84
Increased skin barrier disruption by sodium lauryl sulfate in mice expressing a constitutively active STAT6 in T cells. Arch Dermatol Res (2011) 0.84
Mast Cells Regulate Epidermal Barrier Function and the Development of Allergic Skin Inflammation. J Invest Dermatol (2016) 0.84
Topical application of a vitamin D analogue exacerbates atopic dermatitis and induces the atopic dermatitis-like phenotype in Stat6VT mice. Pediatr Dermatol (2013) 0.83
The signal transducer and activator of transcription 6 gene (STAT6) increases the propensity of patients with atopic dermatitis toward disseminated viral skin infections. J Allergy Clin Immunol (2011) 0.81
Role of IL-9 and STATs in hematological malignancies (Review). Oncol Lett (2013) 0.79
Induction of GITRL expression in human keratinocytes by Th2 cytokines and TNF-α: implications for atopic dermatitis. Clin Exp Allergy (2012) 0.79
STAT6-mediated keratitis and blepharitis: a novel murine model of ocular atopic dermatitis. Invest Ophthalmol Vis Sci (2014) 0.78
Altered cytokine production by dendritic cells from infants with atopic dermatitis. Clin Immunol (2010) 0.76
Transcriptional regulation of T helper type 2 differentiation. Immunology (2014) 0.76
IL-4 impairs wound healing potential in the skin by repressing fibronectin expression. J Allergy Clin Immunol (2016) 0.75
STAT6 and PARP Family Members in the Development of T Cell-dependent Allergic Inflammation. Immune Netw (2016) 0.75
PARP14 limits severity of allergic skin disease. Immunology (2017) 0.75
A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function. Cell Metab (2017) 0.75
Translational Animal Models of Atopic Dermatitis for Preclinical Studies . Yale J Biol Med (2017) 0.75
Stat3 and Stat4 direct development of IL-17-secreting Th cells. J Immunol (2007) 5.16
The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation. Nat Immunol (2010) 3.97
IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells. Proc Natl Acad Sci U S A (2008) 3.04
T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype. Blood (2006) 2.34
A brief history of IL-9. J Immunol (2011) 2.27
IL-23 promotes maintenance but not commitment to the Th17 lineage. J Immunol (2008) 2.06
Signal transducer and activator of transcription 4 is required for the transcription factor T-bet to promote T helper 1 cell-fate determination. Immunity (2008) 2.04
Interferon regulatory factor 4 sustains CD8(+) T cell expansion and effector differentiation. Immunity (2013) 2.03
The transcription factor STAT3 is required for T helper 2 cell development. Immunity (2011) 2.03
PU.1 expression delineates heterogeneity in primary Th2 cells. Immunity (2005) 1.93
Proinflammatory cytokine signaling required for the generation of natural killer cell memory. J Exp Med (2012) 1.89
Transcriptional regulation by STAT6. Immunol Res (2011) 1.81
Human endogenous retrovirus K (HML-2) elements in the plasma of people with lymphoma and breast cancer. J Virol (2008) 1.79
Autonomous murine T-cell progenitor production in the extra-embryonic yolk sac before HSC emergence. Blood (2012) 1.72
STAT6-dependent regulation of Th9 development. J Immunol (2011) 1.60
Interleukin (IL)-4 inhibits IL-10 to promote IL-12 production by dendritic cells. J Exp Med (2005) 1.59
Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins. J Immunol (2007) 1.56
IFN regulatory factor 4 regulates the expression of a subset of Th2 cytokines. J Immunol (2009) 1.51
IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation. J Immunol (2010) 1.49
Interleukin-9 is required for allergic airway inflammation mediated by the cytokine TSLP. Immunity (2013) 1.43
Detection of HERV-K(HML-2) viral RNA in plasma of HIV type 1-infected individuals. AIDS Res Hum Retroviruses (2006) 1.40
Distinct requirements for the naturally occurring splice forms Stat4alpha and Stat4beta in IL-12 responses. EMBO J (2003) 1.39
Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation. EMBO J (2007) 1.34
Stat6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma. Am J Pathol (2002) 1.34
Infected atopic dermatitis lesions contain pharmacologic amounts of lipoteichoic acid. J Allergy Clin Immunol (2009) 1.31
Characterization of human endogenous retroviral elements in the blood of HIV-1-infected individuals. J Virol (2011) 1.26
PU.1 regulates TCR expression by modulating GATA-3 activity. J Immunol (2009) 1.20
BATF transgenic mice reveal a role for activator protein-1 in NKT cell development. J Immunol (2003) 1.19
Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells. Immunology (2009) 1.16
Th9 cell development requires a BATF-regulated transcriptional network. J Clin Invest (2013) 1.15
Thymic selection pathway regulates the effector function of CD4 T cells. J Exp Med (2007) 1.15
Bcl6 controls the Th2 inflammatory activity of regulatory T cells by repressing Gata3 function. J Immunol (2012) 1.13
Regulating Il9 transcription in T helper cells. Trends Immunol (2011) 1.12
IL-4 is a critical determinant in the generation of allergic inflammation initiated by a constitutively active Stat6. J Immunol (2008) 1.12
STAT4 is required for interleukin-12-induced chromatin remodeling of the CD25 locus. J Biol Chem (2003) 1.12
The symphony of the ninth: the development and function of Th9 cells. Curr Opin Immunol (2012) 1.12
Scratching the surface: towards understanding the pathogenesis of atopic dermatitis. Crit Rev Immunol (2008) 1.10
The role of constitutively active Stat6 in leukemia and lymphoma. Crit Rev Oncol Hematol (2005) 1.10
Expression of human endogenous retrovirus type K (HML-2) is activated by the Tat protein of HIV-1. J Virol (2012) 1.10
Predisposition to the development of IL-9-secreting T cells in atopic infants. J Allergy Clin Immunol (2011) 1.10
Gcn5 is required for PU.1-dependent IL-9 induction in Th9 cells. J Immunol (2012) 1.10
Temporal induction pattern of STAT4 target genes defines potential for Th1 lineage-specific programming. J Immunol (2009) 1.10
Cutting edge: induction of the antigen-processing enzyme IFN-gamma-inducible lysosomal thiol reductase in melanoma cells Is STAT1-dependent but CIITA-independent. J Immunol (2004) 1.09
Innate Stat3-mediated induction of the antimicrobial protein Reg3γ is required for host defense against MRSA pneumonia. J Exp Med (2013) 1.08
Th1 cells regulate hematopoietic progenitor cell homeostasis by production of oncostatin M. Immunity (2002) 1.08
Impaired development of human Th1 cells in patients with deficient expression of STAT4. Blood (2009) 1.07
NGSQC: cross-platform quality analysis pipeline for deep sequencing data. BMC Genomics (2010) 1.07
Evaluation of airway reactivity and immune characteristics as risk factors for wheezing early in life. J Allergy Clin Immunol (2010) 1.06
Tc17 cells are capable of mediating immunity to vaccinia virus by acquisition of a cytotoxic phenotype. J Immunol (2010) 1.06
The Bcl6 target gene microRNA-21 promotes Th2 differentiation by a T cell intrinsic pathway. Mol Immunol (2013) 1.06
The environmental stressor ultraviolet B radiation inhibits murine antitumor immunity through its ability to generate platelet-activating factor agonists. Carcinogenesis (2012) 1.05
Bruton's tyrosine kinase is required for TLR-induced IL-10 production. J Immunol (2006) 1.04
HIV infection reveals widespread expansion of novel centromeric human endogenous retroviruses. Genome Res (2013) 1.03
Twist1 regulates Ifng expression in Th1 cells by interfering with Runx3 function. J Immunol (2012) 1.02
Stat6 signaling suppresses VLA-4 expression by CD8+ T cells and limits their ability to infiltrate tumor lesions in vivo. J Immunol (2008) 1.01
Thymic stromal lymphopoietin interferes with airway tolerance by suppressing the generation of antigen-specific regulatory T cells. J Immunol (2011) 1.00
Vaccinia virus blocks Stat1-dependent and Stat1-independent gene expression induced by type I and type II interferons. J Interferon Cytokine Res (2008) 0.99
Stat4 isoforms differentially regulate inflammation and demyelination in experimental allergic encephalomyelitis. J Immunol (2008) 0.98
STAT4 signal pathways regulate inflammation and airway physiology changes in allergic airway inflammation locally via alteration of chemokines. J Immunol (2003) 0.97
Impaired interferon-gamma production as a consequence of STAT4 deficiency after autologous hematopoietic stem cell transplantation for lymphoma. Blood (2005) 0.97
Tobacco and HIV. Clin Occup Environ Med (2006) 0.97
STAT4 requires the N-terminal domain for efficient phosphorylation. J Biol Chem (2003) 0.96
Transcription factor-dependent chromatin remodeling of Il18r1 during Th1 and Th2 differentiation. J Immunol (2008) 0.94
IL-4-stimulated NF-kappaB activity is required for Stat6 DNA binding. J Leukoc Biol (2007) 0.94
Inhibition of weak-affinity epitope-IgE interactions prevents mast cell degranulation. Nat Chem Biol (2013) 0.94
Periostin regulates goblet cell metaplasia in a model of allergic airway inflammation. J Immunol (2011) 0.93
STAT4 deficiency reduces obesity-induced insulin resistance and adipose tissue inflammation. Diabetes (2013) 0.93
Differential roles of C-terminal activation motifs in the establishment of Stat6 transcriptional specificity. J Biol Chem (2003) 0.92
An efferocytosis-induced, IL-4-dependent macrophage-iNKT cell circuit suppresses sterile inflammation and is defective in murine CGD. Blood (2013) 0.92
Cytokine-dependent induction of CD4+ T cells with cytotoxic potential during influenza virus infection. J Virol (2013) 0.92
Constitutive expression of CIITA directs CD4 T cells to produce Th2 cytokines in the thymus. Cell Immunol (2005) 0.92
Agonist-driven development of CD4+CD25+Foxp3+ regulatory T cells requires a second signal mediated by Stat6. J Immunol (2007) 0.91
The homeostasis but not the differentiation of T cells is regulated by p27(Kip1). J Immunol (2002) 0.91
STAT4 isoforms differentially regulate Th1 cytokine production and the severity of inflammatory bowel disease. J Immunol (2008) 0.91
DNA methyltransferase 3a limits the expression of interleukin-13 in T helper 2 cells and allergic airway inflammation. Proc Natl Acad Sci U S A (2011) 0.90
Grap negatively regulates T-cell receptor-elicited lymphocyte proliferation and interleukin-2 induction. Mol Cell Biol (2002) 0.89
Human endogenous retrovirus K Gag coassembles with HIV-1 Gag and reduces the release efficiency and infectivity of HIV-1. J Virol (2012) 0.88
Epigenetic regulation of WTH3 in primary and cultured drug-resistant breast cancer cells. Cancer Res (2005) 0.87
Signal transducer and activator of transcription (Stat)-6-dependent, but not Stat4-dependent, immunity is required for the development of autoimmunity in Graves' hyperthyroidism. Endocrinology (2004) 0.86
Respiratory syncytial virus causes increased bronchial epithelial permeability. Chest (2004) 0.86
Molecular mechanisms of repression of eotaxin expression with fluticasone propionate in airway epithelial cells. Int Arch Allergy Immunol (2004) 0.85
Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation. J Immunol (2013) 0.85
Increased skin barrier disruption by sodium lauryl sulfate in mice expressing a constitutively active STAT6 in T cells. Arch Dermatol Res (2011) 0.84
Wheezing and itching: The requirement for STAT proteins in allergic inflammation. JAKSTAT (2012) 0.84
The transcription factor Twist1 limits T helper 17 and T follicular helper cell development by repressing the gene encoding the interleukin-6 receptor α chain. J Biol Chem (2013) 0.83
Changing the STATus quo in T helper cells. Transcription (2011) 0.83
Topical application of a vitamin D analogue exacerbates atopic dermatitis and induces the atopic dermatitis-like phenotype in Stat6VT mice. Pediatr Dermatol (2013) 0.83
T cell regulation of hematopoiesis. Front Biosci (2008) 0.83
CD4+ T-cell-mediated anti-tumor immunity can be uncoupled from autoimmunity via the STAT4/STAT6 signaling axis. Eur J Immunol (2009) 0.81
The signal transducer and activator of transcription 6 gene (STAT6) increases the propensity of patients with atopic dermatitis toward disseminated viral skin infections. J Allergy Clin Immunol (2011) 0.81
Neonatal tolerance in the absence of Stat4- and Stat6- dependent Th cell differentiation. J Immunol (2002) 0.81
Differential requirement of signal transducer and activator of transcription-4 (Stat4) and Stat6 in a thyrotropin receptor-289-adenovirus-induced model of Graves' hyperthyroidism. Endocrinology (2005) 0.81
Regulation of IL-17 expression by the developmental pathway of CD4 T cells in the thymus. Mol Immunol (2010) 0.81
The transcriptional repressor Bcl6 controls the stability of regulatory T cells by intrinsic and extrinsic pathways. Immunology (2015) 0.80
Elevated IL-6 expression in CD4 T cells via PKCtheta and NF-kappaB induces Th2 cytokine production. Mol Immunol (2009) 0.80
Influence of increased CD4 cell counts on the genetic variability of hepatitis C virus in patients co-infected with human immunodeficiency virus I. J Biomol Tech (2006) 0.80
Identification of staphylococcal protein A in infected atopic dermatitis lesions. J Invest Dermatol (2010) 0.80
T helper cell subsets in the development of atopic dermatitis. J Drugs Dermatol (2012) 0.80
Antisocial networking in T helper cells. Immunity (2010) 0.79