Published in J Immunol on April 01, 2003
Regulatory CD56(bright) natural killer cells mediate immunomodulatory effects of IL-2Ralpha-targeted therapy (daclizumab) in multiple sclerosis. Proc Natl Acad Sci U S A (2006) 4.26
Effect of NKG2D ligand expression on host immune responses. Immunol Rev (2010) 3.08
Regulation of ligands for the NKG2D activating receptor. Annu Rev Immunol (2013) 2.98
Natural killer cells act as rheostats modulating antiviral T cells. Nature (2011) 2.68
Immune surveillance: a balance between protumor and antitumor immunity. Curr Opin Genet Dev (2008) 2.62
Regulation of activated CD4+ T cells by NK cells via the Qa-1-NKG2A inhibitory pathway. Immunity (2007) 2.23
Visualizing fewer than 10 mouse T cells with an enhanced firefly luciferase in immunocompetent mouse models of cancer. Proc Natl Acad Sci U S A (2008) 2.20
Immune reconstitution after double umbilical cord blood stem cell transplantation: comparison with unrelated peripheral blood stem cell transplantation. Biol Blood Marrow Transplant (2011) 2.11
Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells. Nat Med (2013) 2.02
Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity. Proc Natl Acad Sci U S A (2011) 1.98
2B4 acts as a non-major histocompatibility complex binding inhibitory receptor on mouse natural killer cells. J Exp Med (2004) 1.88
Regulation of ligands for the activating receptor NKG2D. Immunology (2007) 1.55
Cytokine complex-expanded natural killer cells improve allogeneic lung transplant function via depletion of donor dendritic cells. Am J Respir Crit Care Med (2013) 1.50
NK cells mediate reduction of GVHD by inhibiting activated, alloreactive T cells while retaining GVT effects. Blood (2010) 1.49
Absence of mouse 2B4 promotes NK cell-mediated killing of activated CD8+ T cells, leading to prolonged viral persistence and altered pathogenesis. J Clin Invest (2010) 1.47
Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell-mediated deletion. J Exp Med (2012) 1.32
Mixed chimerism, lymphocyte recovery, and evidence for early donor-specific unresponsiveness in patients receiving combined kidney and bone marrow transplantation to induce tolerance. Transplantation (2010) 1.25
An integrated view of the regulation of NKG2D ligands. Immunology (2009) 1.23
Unexpected role for granzyme K in CD56bright NK cell-mediated immunoregulation of multiple sclerosis. J Immunol (2011) 1.18
NK cells are effectors for resolvin E1 in the timely resolution of allergic airway inflammation. J Immunol (2011) 1.13
Regulatory NK-cell functions in inflammation and autoimmunity. Mol Med (2009) 1.09
Cytotoxicity of CD56(bright) NK cells towards autologous activated CD4+ T cells is mediated through NKG2D, LFA-1 and TRAIL and dampened via CD94/NKG2A. PLoS One (2012) 1.09
The depletion of NK cells prevents T cell exhaustion to efficiently control disseminating virus infection. J Immunol (2012) 1.03
NK cells controlling virus-specific T cells: Rheostats for acute vs. persistent infections. Virology (2013) 1.01
Evolving role of 2B4/CD244 in T and NK cell responses during virus infection. Front Immunol (2012) 0.99
NKG2D Ligands in Tumor Immunity: Two Sides of a Coin. Front Immunol (2015) 0.98
Elimination in vivo of developing T cells by natural killer cells. J Exp Med (2003) 0.98
Human NK cells kill resting but not activated microglia via NKG2D- and NKp46-mediated recognition. J Immunol (2008) 0.98
Cross-Talks between Natural Killer Cells and Distinct Subsets of Dendritic Cells. Front Immunol (2014) 0.94
Natural killer cells in allogeneic transplantation: effect on engraftment, graft- versus-tumor, and graft-versus-host responses. Biol Blood Marrow Transplant (2009) 0.94
Immune regulatory cells in umbilical cord blood and their potential roles in transplantation tolerance. Crit Rev Oncol Hematol (2010) 0.92
NKG2D splice variants: a reexamination of adaptor molecule associations. Immunogenetics (2006) 0.92
Clinical relevance of natural killer cells following hematopoietic stem cell transplantation. J Cancer (2012) 0.91
Beyond Stressed Self: Evidence for NKG2D Ligand Expression on Healthy Cells. Curr Immunol Rev (2009) 0.91
Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease. Mucosal Immunol (2015) 0.91
Shaping of NK cell responses by the tumor microenvironment. Cancer Microenviron (2012) 0.87
Natural killer cells and their receptors in multiple sclerosis. Brain (2012) 0.87
NKG2D and DNAM-1 activating receptors and their ligands in NK-T cell interactions: role in the NK cell-mediated negative regulation of T cell responses. Front Immunol (2013) 0.86
Recipient NK cell inactivation and intestinal barrier loss are required for MHC-matched graft-versus-host disease. Sci Transl Med (2014) 0.85
Cysteine cathepsins as regulators of the cytotoxicity of NK and T cells. Front Immunol (2014) 0.83
IL-12/15/18-preactivated NK cells suppress GvHD in a mouse model of mismatched hematopoietic cell transplantation. Eur J Immunol (2015) 0.82
Boosting vaccine efficacy the natural (killer) way. Trends Immunol (2015) 0.82
NK cells and their ability to modulate T cells during virus infections. Crit Rev Immunol (2014) 0.80
NK cells interfere with the generation of resistance against mycoplasma respiratory infection following nasal-pulmonary immunization. J Immunol (2009) 0.77
Natural Killer Cells in Graft-versus-Host-Disease after Allogeneic Hematopoietic Cell Transplantation. Front Immunol (2017) 0.75
NKp46+ Innate Lymphoid Cells Dampen Vaginal CD8 T Cell Responses following Local Immunization with a Cholera Toxin-Based Vaccine. PLoS One (2015) 0.75
Recognition and Regulation of T Cells by NK Cells. Front Immunol (2016) 0.75
"Natural Regulators": NK Cells as Modulators of T Cell Immunity. Front Immunol (2016) 0.75
Trypanosoma brucei Co-opts NK Cells to Kill Splenic B2 B Cells. PLoS Pathog (2016) 0.75
T Cells Infiltrating Diseased Liver Express Ligands for the NKG2D Stress Surveillance System. J Immunol (2016) 0.75
Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation. J Exp Med (2017) 0.75
Chronic In Vivo Interaction of Dendritic Cells Expressing the Ligand Rae-1ε with NK Cells Impacts NKG2D Expression and Function. Immunohorizons (2017) 0.75
The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science (2011) 6.01
Maternal immune activation alters fetal brain development through interleukin-6. J Neurosci (2007) 4.06
Neurodevelopmental outcomes in children with congenital heart disease: evaluation and management: a scientific statement from the American Heart Association. Circulation (2012) 3.02
Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia. Cancer Cell (2011) 2.68
Human cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against natural killer cell cytotoxicity. J Exp Med (2003) 2.20
Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells. Blood (2009) 1.99
HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells. Blood (2004) 1.95
Prevalent expression of the immunostimulatory MHC class I chain-related molecule is counteracted by shedding in prostate cancer. J Clin Invest (2004) 1.89
NKp46 and NKG2D recognition of infected dendritic cells is necessary for NK cell activation in the human response to influenza infection. J Immunol (2007) 1.78
Self-reported nonmusculoskeletal responses to chiropractic intervention: a multination survey. J Manipulative Physiol Ther (2005) 1.71
Regional distribution of cortical interneurons and development of inhibitory tone are regulated by Cxcl12/Cxcr4 signaling. J Neurosci (2008) 1.67
Human immunodeficiency virus 1 Nef protein downmodulates the ligands of the activating receptor NKG2D and inhibits natural killer cell-mediated cytotoxicity. J Gen Virol (2007) 1.63
Use of the complete blood cell count in late-onset neonatal sepsis. Pediatr Infect Dis J (2012) 1.63
Down-regulation of the NKG2D ligand MICA by the human cytomegalovirus glycoprotein UL142. Biochem Biophys Res Commun (2006) 1.62
UL16-binding proteins, novel MHC class I-related proteins, bind to NKG2D and activate multiple signaling pathways in primary NK cells. J Immunol (2002) 1.61
LIR-1 expression on lymphocytes, and cytomegalovirus disease in lung-transplant recipients. Lancet (2003) 1.59
A RANK/TRAF6-dependent signal transduction pathway is essential for osteoclast cytoskeletal organization and resorptive function. J Biol Chem (2002) 1.54
ULBP4 is a novel ligand for human NKG2D. Biochem Biophys Res Commun (2003) 1.47
Role of NK cell-activating receptors and their ligands in the lysis of mononuclear phagocytes infected with an intracellular bacterium. J Immunol (2005) 1.39
Cell surface organization of stress-inducible proteins ULBP and MICA that stimulate human NK cells and T cells via NKG2D. J Exp Med (2004) 1.32
NKG2D ligands are expressed on stressed human airway epithelial cells. Am J Physiol Lung Cell Mol Physiol (2006) 1.31
Activation of human eosinophils through leukocyte immunoglobulin-like receptor 7. Proc Natl Acad Sci U S A (2003) 1.30
NK cells lyse T regulatory cells that expand in response to an intracellular pathogen. J Immunol (2008) 1.26
The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma. Blood (2010) 1.24
Intracellular retention of the MHC class I-related chain B ligand of NKG2D by the human cytomegalovirus UL16 glycoprotein. J Immunol (2003) 1.21
A novel inhibitor of glucose uptake sensitizes cells to FAS-induced cell death. Mol Cancer Ther (2008) 1.21
Inhibition of the sodium potassium adenosine triphosphatase pump sensitizes cancer cells to anoikis and prevents distant tumor formation. Cancer Res (2009) 1.18
Inhibition of the sodium/potassium ATPase impairs N-glycan expression and function. Cancer Res (2008) 1.17
Wnt inhibitor screen reveals iron dependence of β-catenin signaling in cancers. Cancer Res (2011) 1.13
Identification of small molecules that sensitize resistant tumor cells to tumor necrosis factor-family death receptors. Cancer Res (2006) 1.11
Soluble ULBP suppresses natural killer cell activity via down-regulating NKG2D expression. Cell Immunol (2006) 1.09
A small-molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway. Blood (2010) 1.09
Cyproheptadine displays preclinical activity in myeloma and leukemia. Blood (2008) 1.08
Use of the complete blood cell count in early-onset neonatal sepsis. Pediatr Infect Dis J (2012) 1.07
The role of BDNF in the pathophysiology and treatment of schizophrenia. J Psychiatr Res (2011) 1.06
Serum B-cell maturation antigen is elevated in multiple myeloma and correlates with disease status and survival. Br J Haematol (2012) 1.06
Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors. J Clin Invest (2012) 1.04
A chemical biology screen identifies glucocorticoids that regulate c-maf expression by increasing its proteasomal degradation through up-regulation of ubiquitin. Blood (2007) 1.03
Selective inhibition of histone deacetylases sensitizes malignant cells to death receptor ligands. Mol Cancer Ther (2010) 1.03
A chemical screen identifies anisomycin as an anoikis sensitizer that functions by decreasing FLIP protein synthesis. Cancer Res (2007) 1.02
The co-expression of activating and inhibitory leukocyte immunoglobulin-like receptors in rheumatoid synovium. Am J Pathol (2002) 1.02
Novel insights into capillary vessel basement membrane damage by snake venom hemorrhagic metalloproteinases: a biochemical and immunohistochemical study. Arch Biochem Biophys (2006) 1.01
KHYG-1, a model for the study of enhanced natural killer cell cytotoxicity. Exp Hematol (2005) 0.98
Critical role for Fas-associated death domain-like interleukin-1-converting enzyme-like inhibitory protein in anoikis resistance and distant tumor formation. J Natl Cancer Inst (2007) 0.97
Oral ciclopirox olamine displays biological activity in a phase I study in patients with advanced hematologic malignancies. Am J Hematol (2014) 0.95
Bisphosphonates and osteonecrosis of the jaw. J Am Geriatr Soc (2011) 0.95
Effect of maternal and postweaning folic acid supplementation on global and gene-specific DNA methylation in the liver of the rat offspring. Mol Nutr Food Res (2013) 0.95
ULBPs, human ligands of the NKG2D receptor, stimulate tumor immunity with enhancement by IL-15. Blood (2006) 0.94
Impact of budget cuts to environmental health services at local health departments: key findings. J Environ Health (2014) 0.93
The tricyclic antidepressant amitriptyline inhibits D-cyclin transactivation and induces myeloma cell apoptosis by inhibiting histone deacetylases: in vitro and in silico evidence. Mol Pharmacol (2011) 0.92
NKG2D splice variants: a reexamination of adaptor molecule associations. Immunogenetics (2006) 0.92
Characterisation of carbon paste electrodes for real-time amperometric monitoring of brain tissue oxygen. J Neurosci Methods (2010) 0.91
Disruption of the endoplasmic reticulum and increases in cytoplasmic calcium are early events in cell death induced by the natural triterpenoid Asiatic acid. Apoptosis (2006) 0.90
Response surface optimization of the heparosan N-deacetylation in producing bioengineered heparin. J Biotechnol (2011) 0.90
Deoxyribonucleic acid methyltransferase 3B promotes epigenetic silencing through histone 3 chromatin modifications in pituitary cells. J Clin Endocrinol Metab (2008) 0.87
Rerouting chlorambucil to mitochondria combats drug deactivation and resistance in cancer cells. Chem Biol (2011) 0.87
Congenital heart disease in Cornelia de Lange syndrome: phenotype and genotype analysis. Am J Med Genet A (2012) 0.86
Inhibition of SREBP1 sensitizes cells to death ligands. Oncotarget (2011) 0.86
Spontaneous mutations in the human CMV HLA class I homologue UL18 affect its binding to the inhibitory receptor LIR-1/ILT2/CD85j. Eur J Immunol (2006) 0.86
The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells. Blood (2010) 0.85
Hemodynamic responses in amygdala and hippocampus distinguish between aversive and neutral cues during Pavlovian fear conditioning in behaving rats. Eur J Neurosci (2012) 0.84
Expression cloning and function of the rat NK activating and inhibitory receptors NKR-P1A and -P1B. Int Immunol (2003) 0.84
Expression of the NKG2D ligand UL16 binding protein-1 (ULBP-1) on dendritic cells. Eur J Immunol (2006) 0.83
Proteomics of wound exudate in snake venom-induced pathology: search for biomarkers to assess tissue damage and therapeutic success. J Proteome Res (2011) 0.83
Endothelial keratoplasty: the relationship between donor tissue size and donor endothelial survival. Ophthalmology (2011) 0.83
Re-directing an alkylating agent to mitochondria alters drug target and cell death mechanism. PLoS One (2013) 0.83
A role for the MHC class I-like Mill molecules in nutrient metabolism and wound healing. Immunol Cell Biol (2008) 0.82
NKG2D-dependent IL-17 production by human T cells in response to an intracellular pathogen. J Immunol (2009) 0.82
Suppression of cancer progression by MGAT1 shRNA knockdown. PLoS One (2012) 0.81
The human cytomegalovirus protein UL16 mediates increased resistance to natural killer cell cytotoxicity through resistance to cytolytic proteins. J Virol (2003) 0.81
A genome wide shRNA screen identifies α/β hydrolase domain containing 4 (ABHD4) as a novel regulator of anoikis resistance. Apoptosis (2012) 0.81
Eight-channel multidetector computed tomography: unique potential for pediatric chest computed tomography angiography. J Thorac Imaging (2002) 0.80
Inactivation of the LysR regulator Cj1000 of Campylobacter jejuni affects host colonization and respiration. Microbiology (2013) 0.80
Characteristics and thirty-day outcomes of emergency department patients with elevated creatine kinase. Acad Emerg Med (2014) 0.80
Structural elements underlying the high binding affinity of human cytomegalovirus UL18 to leukocyte immunoglobulin-like receptor-1. J Mol Biol (2007) 0.80
Preliminary study of the safety and efficacy of donepezil hydrochloride in children with Down syndrome: a clinical report series. Am J Med Genet A (2007) 0.80
Molecular mechanism of telokin-mediated disinhibition of myosin light chain phosphatase and cAMP/cGMP-induced relaxation of gastrointestinal smooth muscle. J Biol Chem (2012) 0.80
Metabolic adaptation to chronic inhibition of mitochondrial protein synthesis in acute myeloid leukemia cells. PLoS One (2013) 0.80
CEP-18770 (delanzomib) in combination with dexamethasone and lenalidomide inhibits the growth of multiple myeloma. Leuk Res (2012) 0.79
Dexamethasone increases ubiquitin transcription through an SP-1 dependent mechanism in multiple myeloma cells. Leuk Res (2008) 0.79
Survival versus neglect: redefining thymocyte subsets based on expression of NKG2D ligand(s) and MHC class I. Eur J Immunol (2005) 0.79
Influence of xenogeneic beta2-microglobulin on functional recognition of H-2Kb by the NK cell inhibitory receptor Ly49C. J Immunol (2005) 0.78
Anti-myeloma effects of the novel anthracycline derivative INNO-206. Clin Cancer Res (2012) 0.78
Mucosa-Associated Ileal Microbiota in New-Onset Pediatric Crohn's Disease. Inflamm Bowel Dis (2016) 0.76
Timing and expression of the angiopoietin-1-Tie-2 pathway in murine lung development and congenital diaphragmatic hernia. Dis Model Mech (2012) 0.76
Mitochondrial DNA damage by bleomycin induces AML cell death. Apoptosis (2015) 0.76
Carnitine transporter CT2 (SLC22A16) is over-expressed in acute myeloid leukemia (AML) and target knockdown reduces growth and viability of AML cells. Apoptosis (2015) 0.76