Published in Proc Natl Acad Sci U S A on April 08, 2003
Identification of a second bovine amyloidotic spongiform encephalopathy: molecular similarities with sporadic Creutzfeldt-Jakob disease. Proc Natl Acad Sci U S A (2004) 3.29
Transmission of prions from mule deer and elk with chronic wasting disease to transgenic mice expressing cervid PrP. J Virol (2004) 2.34
Diagnosis of human prion disease. Proc Natl Acad Sci U S A (2005) 2.13
Transmission of elk and deer prions to transgenic mice. J Virol (2006) 2.03
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Efficient transmission and characterization of Creutzfeldt-Jakob disease strains in bank voles. PLoS Pathog (2006) 1.70
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Conformational transformation and selection of synthetic prion strains. J Mol Biol (2011) 1.66
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Observation of sequence specificity in the seeding of protein amyloid fibrils. Protein Sci (2004) 1.44
Transmission barriers for bovine, ovine, and human prions in transgenic mice. J Virol (2005) 1.43
Inactivation of prions by acidic sodium dodecyl sulfate. J Virol (2006) 1.43
Characterization of truncated forms of abnormal prion protein in Creutzfeldt-Jakob disease. J Biol Chem (2008) 1.40
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Prominent and persistent extraneural infection in human PrP transgenic mice infected with variant CJD. PLoS One (2008) 1.24
Runaway domain swapping in amyloid-like fibrils of T7 endonuclease I. Proc Natl Acad Sci U S A (2006) 1.16
Humanized knock-in mice expressing chimeric prion protein showed varied susceptibility to different human prions. Am J Pathol (2003) 1.16
Prion strain-dependent differences in conversion of mutant prion proteins in cell culture. J Virol (2006) 1.14
Resistance of bovine spongiform encephalopathy (BSE) prions to inactivation. PLoS Pathog (2008) 1.14
Antihypertensive drug guanabenz is active in vivo against both yeast and mammalian prions. PLoS One (2008) 1.13
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Small protease sensitive oligomers of PrPSc in distinct human prions determine conversion rate of PrP(C). PLoS Pathog (2012) 1.07
Human prion strain selection in transgenic mice. Ann Neurol (2010) 1.06
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Evidence that bank vole PrP is a universal acceptor for prions. PLoS Pathog (2014) 1.03
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Molecular pathology of human prion disease. Acta Neuropathol (2010) 1.01
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Mouse models for studying the formation and propagation of prions. J Biol Chem (2014) 0.98
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Rapid and Quantitative Assay of Amyloid-Seeding Activity in Human Brains Affected with Prion Diseases. PLoS One (2015) 0.93
Pharmacokinetics and metabolism of 2-aminothiazoles with antiprion activity in mice. Pharm Res (2013) 0.92
Identification of I137M and other mutations that modulate incubation periods for two human prion strains. J Virol (2012) 0.86
Chimeric elk/mouse prion proteins in transgenic mice. J Gen Virol (2012) 0.85
Co-existence of distinct prion types enables conformational evolution of human PrPSc by competitive selection. J Biol Chem (2013) 0.83
Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation. Ann Neurol (2015) 0.82
Phosphorothioate oligonucleotides reduce PrP levels and prion infectivity in cultured cells. Mol Med (2007) 0.82
Prion protein misfolding, strains, and neurotoxicity: an update from studies on Mammalian prions. Int J Cell Biol (2013) 0.82
No major change in vCJD agent strain after secondary transmission via blood transfusion. PLoS One (2008) 0.81
The glycosylation status of PrPC is a key factor in determining transmissible spongiform encephalopathy transmission between species. J Virol (2015) 0.81
Live cell fluorescence resonance energy transfer predicts an altered molecular association of heterologous PrPSc with PrPC. J Biol Chem (2010) 0.81
Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS. PLoS Pathog (2015) 0.78
Structural effects of PrP polymorphisms on intra- and interspecies prion transmission. Proc Natl Acad Sci U S A (2014) 0.78
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Conserved properties of human and bovine prion strains on transmission to guinea pigs. Lab Invest (2011) 0.78
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Guinea Pig Prion Protein Supports Rapid Propagation of Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease Prions. J Virol (2016) 0.75
Assessing transmissible spongiform encephalopathy species barriers with an in vitro prion protein conversion assay. J Vis Exp (2015) 0.75
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