Published in J Am Chem Soc on April 23, 2003
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep (2013) 5.38
Follow the leader: the use of leader peptides to guide natural product biosynthesis. Nat Chem Biol (2010) 3.16
Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds. Nat Prod Rep (2009) 2.32
Radical S-adenosylmethionine enzymes. Chem Rev (2014) 1.64
The radical SAM enzyme AlbA catalyzes thioether bond formation in subtilosin A. Nat Chem Biol (2012) 1.39
Isolation and characterization of carnocyclin a, a novel circular bacteriocin produced by Carnobacterium maltaromaticum UAL307. Appl Environ Microbiol (2008) 1.19
Ribosomally synthesized and post-translationally modified peptide natural products: new insights into the role of leader and core peptides during biosynthesis. Chemistry (2013) 1.15
Use of a copper-chelated lipid speeds up NMR measurements from membrane proteins. J Am Chem Soc (2010) 1.01
The three-dimensional structure of carnocyclin A reveals that many circular bacteriocins share a common structural motif. J Biol Chem (2009) 0.97
Subtilosin production by two Bacillus subtilis subspecies and variance of the sbo-alb cluster. Appl Environ Microbiol (2004) 0.97
Bacteriocins of lactic acid bacteria: extending the family. Appl Microbiol Biotechnol (2016) 0.96
Amylocyclicin, a novel circular bacteriocin produced by Bacillus amyloliquefaciens FZB42. J Bacteriol (2014) 0.95
The maltose ABC transporter in Lactococcus lactis facilitates high-level sensitivity to the circular bacteriocin garvicin ML. Antimicrob Agents Chemother (2012) 0.95
Revealing nature's synthetic potential through the study of ribosomal natural product biosynthesis. ACS Chem Biol (2013) 0.94
Genome mining for ribosomally synthesized and post-translationally modified peptides (RiPPs) in anaerobic bacteria. BMC Genomics (2014) 0.93
Biochemical and Spectroscopic Characterization of a Radical S-Adenosyl-l-methionine Enzyme Involved in the Formation of a Peptide Thioether Cross-Link. Biochemistry (2016) 0.92
Discovering the bacterial circular proteins: bacteriocins, cyanobactins, and pilins. J Biol Chem (2012) 0.89
Insights into the functionality of the putative residues involved in enterocin AS-48 maturation. Appl Environ Microbiol (2010) 0.87
Cycloquest: identification of cyclopeptides via database search of their mass spectra against genome databases. J Proteome Res (2011) 0.85
Isolation of a variant of subtilosin A with hemolytic activity. J Bacteriol (2009) 0.84
The Enterococcal Cytolysin Synthetase Coevolves with Substrate for Stereoselective Lanthionine Synthesis. ACS Chem Biol (2016) 0.78
Cyclisation mechanisms in the biosynthesis of ribosomally synthesised and post-translationally modified peptides. Beilstein J Org Chem (2016) 0.77
Ribosomal Natural Products, Tailored To Fit. Acc Chem Res (2017) 0.75
Functional Analysis of Genes Involved in the Biosynthesis of Enterocin NKR-5-3B, a Novel Circular Bacteriocin. J Bacteriol (2015) 0.75
Identification and classification of known and putative antimicrobial compounds produced by a wide variety of Bacillales species. BMC Genomics (2016) 0.75
Radical SAM enzymes involved in RiPP biosynthesis. Biochemistry (2017) 0.75
Drug discovery and natural products: end of an era or an endless frontier? Science (2009) 7.54
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep (2013) 5.38
Targeted profiling: quantitative analysis of 1H NMR metabolomics data. Anal Chem (2006) 4.36
Complete reconstitution of a highly reducing iterative polyketide synthase. Science (2009) 2.68
Spx-dependent global transcriptional control is induced by thiol-specific oxidative stress in Bacillus subtilis. Proc Natl Acad Sci U S A (2003) 2.15
Thuricin CD, a posttranslationally modified bacteriocin with a narrow spectrum of activity against Clostridium difficile. Proc Natl Acad Sci U S A (2010) 1.89
A regulatory protein that interferes with activator-stimulated transcription in bacteria. Proc Natl Acad Sci U S A (2003) 1.82
Redox-sensitive transcriptional control by a thiol/disulphide switch in the global regulator, Spx. Mol Microbiol (2005) 1.79
Two-peptide bacteriocins produced by lactic acid bacteria. Biochimie (2002) 1.72
Multiple pathways of Spx (YjbD) proteolysis in Bacillus subtilis. J Bacteriol (2002) 1.65
Structural characterization of lacticin 3147, a two-peptide lantibiotic with synergistic activity. Biochemistry (2004) 1.61
Spatial variability overwhelms seasonal patterns in bacterioplankton communities across a river to ocean gradient. ISME J (2011) 1.56
A molecular explanation for the recessive nature of parkin-linked Parkinson's disease. Nat Commun (2013) 1.51
Structure of subtilosin A, a cyclic antimicrobial peptide from Bacillus subtilis with unusual sulfur to alpha-carbon cross-links: formation and reduction of alpha-thio-alpha-amino acid derivatives. Biochemistry (2004) 1.50
Traceless solid phase synthesis of 2-substituted pyrimidines using an 'off-the-shelf' chlorogermane-functionalised resin. Org Biomol Chem (2003) 1.45
Enzymatic synthesis of resorcylic acid lactones by cooperation of fungal iterative polyketide synthases involved in hypothemycin biosynthesis. J Am Chem Soc (2010) 1.41
The ClpX chaperone modulates assembly of the tubulin-like protein FtsZ. Mol Microbiol (2005) 1.36
Crystal structure of the Bacillus subtilis anti-alpha, global transcriptional regulator, Spx, in complex with the alpha C-terminal domain of RNA polymerase. Proc Natl Acad Sci U S A (2005) 1.32
Metabolite profiling of the intraerythrocytic malaria parasite Plasmodium falciparum by (1)H NMR spectroscopy. NMR Biomed (2009) 1.30
Serine and threonine beta-lactones: a new class of hepatitis A virus 3C cysteine proteinase inhibitors. J Org Chem (2002) 1.25
Competing allosteric mechanisms modulate substrate binding in a dimeric enzyme. Nat Struct Mol Biol (2011) 1.20
Isolation and characterization of carnocyclin a, a novel circular bacteriocin produced by Carnobacterium maltaromaticum UAL307. Appl Environ Microbiol (2008) 1.19
A fungal ketoreductase domain that displays substrate-dependent stereospecificity. Nat Chem Biol (2012) 1.17
In situ orientations of protein domains: troponin C in skeletal muscle fibers. Mol Cell (2003) 1.17
Insights into radicicol biosynthesis via heterologous synthesis of intermediates and analogs. J Biol Chem (2010) 1.17
Biosynthesis of lovastatin and related metabolites formed by fungal iterative PKS enzymes. Biopolymers (2010) 1.15
Sulfate-dependent repression of genes that function in organosulfur metabolism in Bacillus subtilis requires Spx. J Bacteriol (2005) 1.15
Spx (YjbD), a negative effector of competence in Bacillus subtilis, enhances ClpC-MecA-ComK interaction. Mol Microbiol (2002) 1.15
Structural insights into stereochemical inversion by diaminopimelate epimerase: an antibacterial drug target. Proc Natl Acad Sci U S A (2006) 1.14
Regulation of quinone detoxification by the thiol stress sensing DUF24/MarR-like repressor, YodB in Bacillus subtilis. Mol Microbiol (2008) 1.09
The YjbH protein of Bacillus subtilis enhances ClpXP-catalyzed proteolysis of Spx. J Bacteriol (2008) 1.09
Structure and genetics of circular bacteriocins. Trends Microbiol (2011) 1.08
Solid supported chemical syntheses of both components of the lantibiotic lacticin 3147. J Am Chem Soc (2011) 1.08
Structural model of the BCL-w-BID peptide complex and its interactions with phospholipid micelles. Biochemistry (2006) 1.08
Mutational analysis of the Bacillus subtilis RNA polymerase alpha C-terminal domain supports the interference model of Spx-dependent repression. J Bacteriol (2006) 1.06
Isolation, structural characterization, and properties of mattacin (polymyxin M), a cyclic peptide antibiotic produced by Paenibacillus kobensis M. J Biol Chem (2003) 1.05
Crystal structure of LL-diaminopimelate aminotransferase from Arabidopsis thaliana: a recently discovered enzyme in the biosynthesis of L-lysine by plants and Chlamydia. J Mol Biol (2007) 1.05
The global regulator Spx functions in the control of organosulfur metabolism in Bacillus subtilis. J Bacteriol (2006) 1.05
Loss of Apelin exacerbates myocardial infarction adverse remodeling and ischemia-reperfusion injury: therapeutic potential of synthetic Apelin analogues. J Am Heart Assoc (2013) 1.05
Membrane permeabilization, orientation, and antimicrobial mechanism of subtilosin A. Chem Phys Lipids (2005) 1.03
Dual negative control of spx transcription initiation from the P3 promoter by repressors PerR and YodB in Bacillus subtilis. J Bacteriol (2006) 1.03
Synthesis of oxytocin analogues with replacement of sulfur by carbon gives potent antagonists with increased stability. J Org Chem (2005) 1.03
Proteomic signatures uncover thiol-specific electrophile resistance mechanisms in Bacillus subtilis. Expert Rev Proteomics (2008) 1.02
Fundamental functionality: recent developments in understanding the structure-activity relationships of lantibiotic peptides. J Antibiot (Tokyo) (2010) 1.02
Apoptotic regulation by MCL-1 through heterodimerization. J Biol Chem (2010) 1.02
Synthesis of the lantibiotic lactocin S using peptide cyclizations on solid phase. J Am Chem Soc (2010) 1.01
Use of a copper-chelated lipid speeds up NMR measurements from membrane proteins. J Am Chem Soc (2010) 1.01
Activation of transcription initiation by Spx: formation of transcription complex and identification of a Cis-acting element required for transcriptional activation. Mol Microbiol (2008) 1.01
Synthesis and evaluation of keto-glutamine analogues as potent inhibitors of severe acute respiratory syndrome 3CLpro. J Med Chem (2004) 1.01
Biosynthesis of aminovinyl-cysteine-containing peptides and its application in the production of potential drug candidates. Acc Chem Res (2011) 1.00
Synthesis of beta-cyclopropylalanines by photolysis of diacyl peroxides. Org Lett (2003) 1.00
Structural characterization of the highly cyclized lantibiotic paenicidin A via a partial desulfurization/reduction strategy. J Am Chem Soc (2012) 0.99
Promoter recognition by a complex of Spx and the C-terminal domain of the RNA polymerase alpha subunit. PLoS One (2010) 0.99
Photolysis of diacyl peroxides: a radical-based approach for the synthesis of functionalized amino acids. Org Lett (2003) 0.99
Identification and comparison of natural rubber from two Lactuca species. Phytochemistry (2006) 0.98
The 3D structure of thuricin CD, a two-component bacteriocin with cysteine sulfur to α-carbon cross-links. J Am Chem Soc (2011) 0.97
The three-dimensional structure of carnocyclin A reveals that many circular bacteriocins share a common structural motif. J Biol Chem (2009) 0.97
Heat-induced dimerization of BCL-xL through alpha-helix swapping. Biochemistry (2007) 0.97
Crystal structure and biochemical studies of the trans-acting polyketide enoyl reductase LovC from lovastatin biosynthesis. Proc Natl Acad Sci U S A (2012) 0.96
Development of Class IIa Bacteriocins as Therapeutic Agents. Int J Microbiol (2011) 0.96
Structure and biosynthesis of carnolysin, a homologue of enterococcal cytolysin with D-amino acids. J Am Chem Soc (2014) 0.96
Response of methicillin-resistant Staphylococcus aureus to amicoumacin A. PLoS One (2012) 0.95
The circular bacteriocin, carnocyclin A, forms anion-selective channels in lipid bilayers. Biochim Biophys Acta (2009) 0.94
Synthesis of biologically active dicarba analogues of the peptide hormone oxytocin using ring-closing metathesis. Org Lett (2003) 0.94
Requirement of the zinc-binding domain of ClpX for Spx proteolysis in Bacillus subtilis and effects of disulfide stress on ClpXP activity. J Bacteriol (2007) 0.93
The dilated cardiomyopathy G159D mutation in cardiac troponin C weakens the anchoring interaction with troponin I. Biochemistry (2008) 0.93
Exploration of inhibitors for diaminopimelate aminotransferase. Bioorg Med Chem (2010) 0.92
Seasonal changes in bacterial and archaeal gene expression patterns across salinity gradients in the Columbia River coastal margin. PLoS One (2010) 0.92
Double oxidation of the cyclic nonaketide dihydromonacolin L to monacolin J by a single cytochrome P450 monooxygenase, LovA. J Am Chem Soc (2011) 0.92
Biochemical, structural, and genetic characterization of tridecaptin A₁, an antagonist of Campylobacter jejuni. Chembiochem (2013) 0.92
NMR solution structure of the precursor for carnobacteriocin B2, an antimicrobial peptide from Carnobacterium piscicola. Eur J Biochem (2004) 0.92
Synthesis of mono- and disaccharide analogs of moenomycin and lipid II for inhibition of transglycosylase activity of penicillin-binding protein 1b. Bioorg Med Chem (2004) 0.92
Paenibacillus polymyxa PKB1 produces variants of polymyxin B-type antibiotics. Chem Biol (2011) 0.92
LovG: the thioesterase required for dihydromonacolin L release and lovastatin nonaketide synthase turnover in lovastatin biosynthesis. Angew Chem Int Ed Engl (2013) 0.92
The MarR-type repressor MhqR (YkvE) regulates multiple dioxygenases/glyoxalases and an azoreductase which confer resistance to 2-methylhydroquinone and catechol in Bacillus subtilis. Mol Microbiol (2007) 0.91
Dual modes of modification of hepatitis A virus 3C protease by a serine-derived beta-lactone: selective crystallization and formation of a functional catalytic triad in the active site. J Mol Biol (2005) 0.91
The 3D solution structure of thurincin H, a bacteriocin with four sulfur to α-carbon crosslinks. Angew Chem Int Ed Engl (2011) 0.90
Syntheses of conjugated pyrones for the enzymatic assay of lovastatin nonaketide synthase, an iterative polyketide synthase. Org Lett (2007) 0.90
Solid-supported synthesis and biological evaluation of the lantibiotic peptide bis(desmethyl) lacticin 3147 A2. Angew Chem Int Ed Engl (2008) 0.90
NMR solution structure of ImB2, a protein conferring immunity to antimicrobial activity of the type IIa bacteriocin, carnobacteriocin B2. Biochemistry (2004) 0.89
NMR solution structure of a highly stable de novo heterodimeric coiled-coil. Biopolymers (2004) 0.89
Crystal structure of diaminopimelate epimerase from Arabidopsis thaliana, an amino acid racemase critical for L-lysine biosynthesis. J Mol Biol (2008) 0.89
Mechanism of substrate recognition and PLP-induced conformational changes in LL-diaminopimelate aminotransferase from Arabidopsis thaliana. J Mol Biol (2008) 0.89
Design, synthesis, and evaluation of inhibitors for severe acute respiratory syndrome 3C-like protease based on phthalhydrazide ketones or heteroaromatic esters. J Med Chem (2007) 0.89
Solution structure of the orphan PABC domain from Saccharomyces cerevisiae poly(A)-binding protein. J Biol Chem (2002) 0.89
The substrate-bound crystal structure of a Baeyer-Villiger monooxygenase exhibits a Criegee-like conformation. J Am Chem Soc (2012) 0.89
Dynamic relationships among type IIa bacteriocins: temperature effects on antimicrobial activity and on structure of the C-terminal amphipathic alpha helix as a receptor-binding region. Biochemistry (2004) 0.88
Transcriptomic and phenotypic analysis of paralogous spx gene function in Bacillus anthracis Sterne. Microbiologyopen (2013) 0.87
Ubiquitous dissolved inorganic carbon assimilation by marine bacteria in the Pacific Northwest coastal ocean as determined by stable isotope probing. PLoS One (2012) 0.87
Multiple on-resin olefin metathesis to form ring-expanded analogues of the lantibiotic peptide, lacticin 3147 A2. Org Lett (2007) 0.87