Published in Biol Chem on March 01, 2003
Murine cystathionine gamma-lyase: complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expression. Biochem J (2004) 2.59
Current therapeutics, their problems, and sulfur-containing-amino-acid metabolism as a novel target against infections by "amitochondriate" protozoan parasites. Clin Microbiol Rev (2007) 1.45
PLP-dependent H(2)S biogenesis. Biochim Biophys Acta (2011) 1.29
Identification and functional analysis of the gene encoding methionine-gamma-lyase in Brevibacterium linens. Appl Environ Microbiol (2004) 1.09
Kinetic properties of polymorphic variants and pathogenic mutants in human cystathionine gamma-lyase. Biochemistry (2008) 0.98
Cystathionine gamma-lyase is a component of cystine-mediated oxidative defense in Lactobacillus reuteri BR11. J Bacteriol (2009) 0.91
The widespread role of non-enzymatic reactions in cellular metabolism. Curr Opin Biotechnol (2015) 0.89
Structure of the cystathionine γ-synthase MetB from Mycobacterium ulcerans. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.83
Characterization of site-directed mutants of residues R58, R59, D116, W340 and R372 in the active site of E. coli cystathionine beta-lyase. Protein Sci (2010) 0.80
Identification of methionine γ-lyase in genomes of some pathogenic bacteria. Dokl Biochem Biophys (2012) 0.80
A novel mechanism of sulfur transfer catalyzed by O-acetylhomoserine sulfhydrylase in the methionine-biosynthetic pathway of Wolinella succinogenes. Acta Crystallogr D Biol Crystallogr (2011) 0.78
Exploration of the active site of Escherichia coli cystathionine γ-synthase. Protein Sci (2012) 0.75
Expression, purification and preliminary crystallographic analysis of O-acetylhomoserine sulfhydrylase from Mycobacterium tuberculosis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.75
Crystallographic and mutational analyses of cystathionine β-synthase in the H2 S-synthetic gene cluster in Lactobacillus plantarum. Protein Sci (2017) 0.75
Structural snapshots of an engineered cystathionine-Υ-lyase reveal the critical role of electrostatic interactions in the active-site. Biochemistry (2017) 0.75
Expression, crystallization and preliminary X-ray crystallographic analysis of cystathionine γ-synthase (XometB) from Xanthomonas oryzae pv. oryzae. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.75
Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease. Cell (2004) 3.54
Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5. J Mol Biol (2008) 3.27
CASK Functions as a Mg2+-independent neurexin kinase. Cell (2008) 3.10
Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine. Nature (2002) 3.05
Multi-megahertz OCT: High quality 3D imaging at 20 million A-scans and 4.5 GVoxels per second. Opt Express (2010) 3.04
A NusE:NusG complex links transcription and translation. Science (2010) 3.03
Ultrahigh-speed optical coherence tomography for three-dimensional and en face imaging of the retina and optic nerve head. Invest Ophthalmol Vis Sci (2008) 3.01
Structural basis for the function of the ribosomal L7/12 stalk in factor binding and GTPase activation. Cell (2005) 2.97
The genome sequence of the extreme thermophile Thermus thermophilus. Nat Biotechnol (2004) 2.95
Helical extension of the neuronal SNARE complex into the membrane. Nature (2009) 2.92
Fighting fruit flies: a model system for the study of aggression. Proc Natl Acad Sci U S A (2002) 2.66
Megahertz OCT for ultrawide-field retinal imaging with a 1050 nm Fourier domain mode-locked laser. Opt Express (2011) 2.62
Structural basis for the regulated protease and chaperone function of DegP. Nature (2008) 2.56
The crystal structure of the proprotein processing proteinase furin explains its stringent specificity. Nat Struct Biol (2003) 2.42
1.8 A bright-state structure of the reversibly switchable fluorescent protein Dronpa guides the generation of fast switching variants. Biochem J (2007) 2.33
Photothermal detection of gold nanoparticles using phase-sensitive optical coherence tomography. Opt Express (2008) 2.24
A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism. Nature (2008) 2.22
Structure and mechanism of the reversible photoswitch of a fluorescent protein. Proc Natl Acad Sci U S A (2005) 2.21
Structural basis for reversible photoswitching in Dronpa. Proc Natl Acad Sci U S A (2007) 2.08
Molecular details of cAMP generation in mammalian cells: a tale of two systems. J Mol Biol (2006) 2.05
Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons? Hum Mol Genet (2002) 2.05
Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range. Opt Express (2009) 2.03
HTRA proteases: regulated proteolysis in protein quality control. Nat Rev Mol Cell Biol (2011) 2.01
Gender-selective patterns of aggressive behavior in Drosophila melanogaster. Proc Natl Acad Sci U S A (2004) 1.99
Crystal structures of Salinosporamide A (NPI-0052) and B (NPI-0047) in complex with the 20S proteasome reveal important consequences of beta-lactone ring opening and a mechanism for irreversible binding. J Am Chem Soc (2006) 1.96
Proteolysis as a regulatory mechanism. Annu Rev Genet (2004) 1.93
Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation. Nature (2003) 1.92
The role of human HtrA1 in arthritic disease. J Biol Chem (2005) 1.91
Molecular machines for protein degradation. Chembiochem (2005) 1.81
Crystal structures of transcription factor NusG in light of its nucleic acid- and protein-binding activities. EMBO J (2002) 1.79
Crystal structure of protoporphyrinogen IX oxidase: a key enzyme in haem and chlorophyll biosynthesis. EMBO J (2004) 1.75
A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching. Nat Biotechnol (2011) 1.74
Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa. Mol Cell (2007) 1.70
Phase-sensitive optical coherence tomography at up to 370,000 lines per second using buffered Fourier domain mode-locked lasers. Opt Lett (2007) 1.69
Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP. Science (2007) 1.64
K-space linear Fourier domain mode locked laser and applications for optical coherence tomography. Opt Express (2008) 1.62
The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism. Proc Natl Acad Sci U S A (2003) 1.62
Improved spectral optical coherence tomography using optical frequency comb. Opt Express (2008) 1.58
Catalysis at a dinuclear [CuSMo(==O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution. Proc Natl Acad Sci U S A (2002) 1.57
Aggression in invertebrates. Curr Opin Neurobiol (2003) 1.53
SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase. Mol Cell (2013) 1.52
A functional Ni-Ni-[4Fe-4S] cluster in the monomeric acetyl-CoA synthase from Carboxydothermus hydrogenoformans. Proc Natl Acad Sci U S A (2003) 1.52
Behavioral functions of the mesolimbic dopaminergic system: an affective neuroethological perspective. Brain Res Rev (2007) 1.50
Structure and function of an RNase H domain at the heart of the spliceosome. EMBO J (2008) 1.49
Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins. Proc Natl Acad Sci U S A (2008) 1.48
Implications of the serine protease HtrA1 in amyloid precursor protein processing. Proc Natl Acad Sci U S A (2005) 1.47
Structure of the metal-independent restriction enzyme BfiI reveals fusion of a specific DNA-binding domain with a nonspecific nuclease. Proc Natl Acad Sci U S A (2005) 1.47
Gene transfer and genome plasticity in Thermotoga maritima, a model hyperthermophilic species. J Bacteriol (2005) 1.45
Crystal structure of the guanylyl cyclase Cya2. Proc Natl Acad Sci U S A (2008) 1.44
Mutations in the β-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities. Cell Rep (2012) 1.43
Crystal structure of the p14/MP1 scaffolding complex: how a twin couple attaches mitogen-activated protein kinase signaling to late endosomes. Proc Natl Acad Sci U S A (2004) 1.43
Augmenting β-augmentation: structural basis of how BamB binds BamA and may support folding of outer membrane proteins. J Mol Biol (2011) 1.42
Cryptococcus neoformans senses CO2 through the carbonic anhydrase Can2 and the adenylyl cyclase Cac1. Eukaryot Cell (2006) 1.41
Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol 4-phosphate synthase (IspC). Implications for the catalytic mechanism and anti-malaria drug development. J Biol Chem (2003) 1.40
Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity. Structure (2003) 1.39
The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link. Proc Natl Acad Sci U S A (2002) 1.38
Structural and functional analysis of the E. coli NusB-S10 transcription antitermination complex. Mol Cell (2008) 1.37
Multi-MHz retinal OCT. Biomed Opt Express (2013) 1.36
Mechanism of the six-electron reduction of nitrite to ammonia by cytochrome c nitrite reductase. J Am Chem Soc (2002) 1.36
Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach. Biochim Biophys Acta (2004) 1.36
Functional organization of the Sm core in the crystal structure of human U1 snRNP. EMBO J (2010) 1.35
Expansion of the genetic code enables design of a novel "gold" class of green fluorescent proteins. J Mol Biol (2003) 1.34
Structure of the streptococcal endopeptidase IdeS, a cysteine proteinase with strict specificity for IgG. Proc Natl Acad Sci U S A (2004) 1.32
Common design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase. Mol Cell (2009) 1.32
Investigations on the maturation and regulation of archaebacterial proteasomes. J Mol Biol (2003) 1.32
High-resolution positional tracking for long-term analysis of Drosophila sleep and locomotion using the "tracker" program. PLoS One (2012) 1.30
Structure of the stapled p53 peptide bound to Mdm2. J Am Chem Soc (2011) 1.30
Early endosomal SNAREs form a structurally conserved SNARE complex and fuse liposomes with multiple topologies. EMBO J (2006) 1.30
HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues. Nat Struct Mol Biol (2010) 1.30
Substrate access and processing by the 20S proteasome core particle. Int J Biochem Cell Biol (2003) 1.29
Protein quality control in the bacterial periplasm. Annu Rev Microbiol (2011) 1.29
Catalytic domain structures of MT-SP1/matriptase, a matrix-degrading transmembrane serine proteinase. J Biol Chem (2001) 1.27
Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein. Proc Natl Acad Sci U S A (2003) 1.27
A molecular mechanism for direct sirtuin activation by resveratrol. PLoS One (2012) 1.26
Structure and catalytic mechanism of eukaryotic selenocysteine synthase. J Biol Chem (2007) 1.26
Ultrahigh-speed non-invasive widefield angiography. J Biomed Opt (2012) 1.25
Crystal structures of the tricorn interacting factor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations. J Mol Biol (2005) 1.25
New isolates and physiological properties of the Aquificales and description of Thermocrinis albus sp. nov. Extremophiles (2002) 1.24
Crystal structure of the Bse634I restriction endonuclease: comparison of two enzymes recognizing the same DNA sequence. Nucleic Acids Res (2002) 1.24
Crystal structure of 12-oxophytodienoate reductase 3 from tomato: self-inhibition by dimerization. Proc Natl Acad Sci U S A (2006) 1.24
Gene sequence and the 1.8 A crystal structure of the tungsten-containing formate dehydrogenase from Desulfovibrio gigas. Structure (2002) 1.23
A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors. EMBO J (2013) 1.21
Stress-induced GSK3 regulates the redox stress response by phosphorylating glucose-6-phosphate dehydrogenase in Arabidopsis. Plant Cell (2012) 1.20
Crystal structure of the dinuclear zinc aminopeptidase PepV from Lactobacillus delbrueckii unravels its preference for dipeptides. Structure (2002) 1.20
Biochemical characterization of Bacillus subtilis type II isopentenyl diphosphate isomerase, and phylogenetic distribution of isoprenoid biosynthesis pathways. Eur J Biochem (2004) 1.20
Allosteric activation of HtrA protease DegP by stress signals during bacterial protein quality control. Angew Chem Int Ed Engl (2008) 1.19
The unique structure of archaeal 'hami', highly complex cell appendages with nano-grappling hooks. Mol Microbiol (2005) 1.19
Flavin mononucleotide-based fluorescent reporter proteins outperform green fluorescent protein-like proteins as quantitative in vivo real-time reporters. Appl Environ Microbiol (2010) 1.19
Crystal structure of the human CCA-adding enzyme: insights into template-independent polymerization. J Mol Biol (2003) 1.19
McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR. Science (2009) 1.19