Published in Proc Natl Acad Sci U S A on April 26, 2005
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Cerebral small vessel disease-related protease HtrA1 processes latent TGF-β binding protein 1 and facilitates TGF-β signaling. Proc Natl Acad Sci U S A (2014) 1.19
Identification of a novel HtrA1-susceptible cleavage site in human aggrecan: evidence for the involvement of HtrA1 in aggrecan proteolysis in vivo. J Biol Chem (2009) 1.17
Serine protease HtrA1 associates with microtubules and inhibits cell migration. Mol Cell Biol (2009) 1.12
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Newly folded substrates inside the molecular cage of the HtrA chaperone DegQ. Nat Struct Mol Biol (2012) 0.93
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The novel role of HtrA1 in gingivitis, chronic and aggressive periodontitis. PLoS One (2014) 0.77
Alpha-1-antitrypsin: a novel human high temperature requirement protease A1 (HTRA1) substrate in human placental tissue. PLoS One (2014) 0.77
Protoporphyrins enhance oligomerization and enzymatic activity of HtrA1 serine protease. PLoS One (2014) 0.76
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Uptake of the proteins HTRA1 and HTRA2 by cells mediated by calcium phosphate nanoparticles. Beilstein J Nanotechnol (2017) 0.75
Protective effects of an HTRA1 insertion-deletion variant against age-related macular degeneration in the Chinese populations. Lab Invest (2016) 0.75
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Escherichia coli DegP protease cleaves between paired hydrophobic residues in a natural substrate: the PapA pilin. J Bacteriol (2002) 1.16
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High resolution proteome analysis of cryoglobulins using Fourier transform-ion cyclotron resonance mass spectrometry. Proteomics (2003) 0.78
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration. Science (2006) 5.67
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Structural basis for the regulated protease and chaperone function of DegP. Nature (2008) 2.56
Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer. J Biol Chem (2003) 2.40
Increased myocardial apoptosis in patients with unfavorable left ventricular remodeling and early symptomatic post-infarction heart failure. J Am Coll Cardiol (2003) 2.30
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Widespread myocardial inflammation and infarct-related artery patency. Circulation (2004) 2.27
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Effect of class IV laser therapy on chemotherapy-induced oral mucositis: a clinical and experimental study. Am J Pathol (2013) 2.09
Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling. Nat Med (2005) 2.06
Successful immune tolerance induction to enzyme replacement therapy in CRIM-negative infantile Pompe disease. Genet Med (2012) 2.05
ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome. Nat Methods (2007) 2.04
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Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils. Blood (2007) 1.92
The role of human HtrA1 in arthritic disease. J Biol Chem (2005) 1.91
Human CHN1 mutations hyperactivate alpha2-chimaerin and cause Duane's retraction syndrome. Science (2008) 1.84
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Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins. Proc Natl Acad Sci U S A (2008) 1.48
A candidate tumor suppressor HtrA1 is downregulated in ovarian cancer. Oncogene (2004) 1.47
Pathophysiologic role of myocardial apoptosis in post-infarction left ventricular remodeling. J Cell Physiol (2002) 1.47
Early detection of ovarian cancer: promise and reality. Cancer Treat Res (2002) 1.45
A role for IL-27p28 as an antagonist of gp130-mediated signaling. Nat Immunol (2010) 1.44
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APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma. Cancer Res (2013) 1.43
Crystal structure of the p14/MP1 scaffolding complex: how a twin couple attaches mitogen-activated protein kinase signaling to late endosomes. Proc Natl Acad Sci U S A (2004) 1.43
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Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31. Nat Commun (2013) 1.36
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