Published in Nat Cell Biol on May 01, 2003
Polo-like kinases: conservation and divergence in their functions and regulation. Nat Rev Mol Cell Biol (2009) 4.09
The Mus81 solution to resolution: generating meiotic crossovers without Holliday junctions. Genes Dev (2004) 2.89
Economy, speed and size matter: evolutionary forces driving nuclear genome miniaturization and expansion. Ann Bot (2005) 2.43
Delineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvase. Cell (2012) 2.36
Chiasma formation: chromatin/axis interplay and the role(s) of the synaptonemal complex. Chromosoma (2006) 2.20
Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis. Cell (2011) 2.08
Kinetochore orientation during meiosis is controlled by Aurora B and the monopolin complex. Cell (2007) 2.00
Meiotic chromosome synapsis-promoting proteins antagonize the anti-crossover activity of sgs1. PLoS Genet (2006) 1.98
Sporulation in the budding yeast Saccharomyces cerevisiae. Genetics (2011) 1.88
BLM helicase ortholog Sgs1 is a central regulator of meiotic recombination intermediate metabolism. Mol Cell (2012) 1.81
RecQ helicase, Sgs1, and XPF family endonuclease, Mus81-Mms4, resolve aberrant joint molecules during meiotic recombination. Mol Cell (2008) 1.68
Mutations in Drosophila Greatwall/Scant reveal its roles in mitosis and meiosis and interdependence with Polo kinase. PLoS Genet (2007) 1.66
Polo-like kinase Cdc5 drives exit from pachytene during budding yeast meiosis. Genes Dev (2008) 1.66
Rec8 phosphorylation by casein kinase 1 and Cdc7-Dbf4 kinase regulates cohesin cleavage by separase during meiosis. Dev Cell (2010) 1.61
Mus81/Mms4 endonuclease and Sgs1 helicase collaborate to ensure proper recombination intermediate metabolism during meiosis. Mol Cell (2008) 1.61
Evolution of Ime2 phosphorylation sites on Cdk1 substrates provides a mechanism to limit the effects of the phosphatase Cdc14 in meiosis. Mol Cell (2007) 1.48
Infrequent co-conversion of markers flanking a meiotic recombination initiation site in Saccharomyces cerevisiae. Genetics (2005) 1.45
GEN1/Yen1 and the SLX4 complex: Solutions to the problem of Holliday junction resolution. Genes Dev (2010) 1.44
Meiotic telomere clustering requires actin for its formation and cohesin for its resolution. J Cell Biol (2005) 1.42
Shugoshin-PP2A counteracts casein-kinase-1-dependent cleavage of Rec8 by separase. Nat Cell Biol (2010) 1.40
Casein kinase 1 is required for efficient removal of Rec8 during meiosis I. Cell Cycle (2010) 1.36
LAB-1 antagonizes the Aurora B kinase in C. elegans. Genes Dev (2008) 1.29
Dissociation of the Nuf2-Ndc80 complex releases centromeres from the spindle-pole body during meiotic prophase in fission yeast. Mol Biol Cell (2005) 1.27
Role of cleavage by separase of the Rec8 kleisin subunit of cohesin during mammalian meiosis I. J Cell Sci (2009) 1.24
The multiple roles of cohesin in meiotic chromosome morphogenesis and pairing. Mol Biol Cell (2008) 1.24
Coupling meiotic chromosome axis integrity to recombination. Genes Dev (2008) 1.23
Meikin is a conserved regulator of meiosis-I-specific kinetochore function. Nature (2014) 1.14
Emerging roles for centromeres in meiosis I chromosome segregation. Nat Rev Genet (2008) 1.14
Mus81-Mms4 functions as a single heterodimer to cleave nicked intermediates in recombinational DNA repair. Mol Cell Biol (2012) 1.13
Meiotic recombination intermediates are resolved with minimal crossover formation during return-to-growth, an analogue of the mitotic cell cycle. PLoS Genet (2011) 1.13
Integration of a splicing regulatory network within the meiotic gene expression program of Saccharomyces cerevisiae. Genes Dev (2010) 1.10
Studies of meiosis disclose distinct roles of cohesion in the core centromere and pericentromeric regions. Chromosome Res (2009) 1.08
Shugoshin prevents cohesin cleavage by PP2A(Cdc55)-dependent inhibition of separase. Genes Dev (2009) 1.08
Meiosis I chromosome segregation is established through regulation of microtubule-kinetochore interactions. Elife (2012) 1.08
The Sum1/Ndt80 transcriptional switch and commitment to meiosis in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (2012) 1.07
Novel functional dissection of the localization-specific roles of budding yeast polo kinase Cdc5p. Mol Cell Biol (2004) 1.07
Cdc7-Dbf4 regulates NDT80 transcription as well as reductional segregation during budding yeast meiosis. Mol Biol Cell (2008) 1.02
Positive regulation of meiotic DNA double-strand break formation by activation of the DNA damage checkpoint kinase Mec1(ATR). Open Biol (2013) 1.02
From equator to pole: splitting chromosomes in mitosis and meiosis. Genes Dev (2015) 1.01
What makes centromeric cohesion resistant to separase cleavage during meiosis I but not during meiosis II? Cell Cycle (2007) 1.01
Condensins promote coorientation of sister chromatids during meiosis I in budding yeast. Genetics (2010) 1.01
DNA double-strand break repair in Caenorhabditis elegans. Chromosoma (2010) 1.00
The role of shugoshin in meiotic chromosome segregation. Cytogenet Genome Res (2011) 0.99
Smc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisions. PLoS Genet (2013) 0.99
Mek1 kinase governs outcomes of meiotic recombination and the checkpoint response. Curr Biol (2010) 0.98
Yeast axial-element protein, Red1, binds SUMO chains to promote meiotic interhomologue recombination and chromosome synapsis. EMBO J (2009) 0.98
Chromosome segregation in budding yeast: sister chromatid cohesion and related mechanisms. Genetics (2014) 0.97
Recombination protein Tid1p controls resolution of cohesin-dependent linkages in meiosis in Saccharomyces cerevisiae. J Cell Biol (2005) 0.97
Cis-effects on meiotic recombination across distinct a1-sh2 intervals in a common Zea genetic background. Genetics (2005) 0.97
Top3-Rmi1 DNA single-strand decatenase is integral to the formation and resolution of meiotic recombination intermediates. Mol Cell (2015) 0.95
The Lrs4-Csm1 monopolin complex associates with kinetochores during anaphase and is required for accurate chromosome segregation. Cell Cycle (2010) 0.94
Meiotic cohesin promotes pairing of nonhomologous centromeres in early meiotic prophase. Mol Biol Cell (2010) 0.93
The Aurora kinase Ipl1 is necessary for spindle pole body cohesion during budding yeast meiosis. J Cell Sci (2011) 0.91
Polo-like kinase is required for synaptonemal complex disassembly and phosphorylation in mouse spermatocytes. J Cell Sci (2012) 0.91
Ipl1/Aurora B kinase coordinates synaptonemal complex disassembly with cell cycle progression and crossover formation in budding yeast meiosis. Genes Dev (2009) 0.89
Smc5/6-Mms21 prevents and eliminates inappropriate recombination intermediates in meiosis. PLoS Genet (2013) 0.89
Shugoshins: tension-sensitive pericentromeric adaptors safeguarding chromosome segregation. Mol Cell Biol (2014) 0.89
Meiosis: an overview of key differences from mitosis. Cold Spring Harb Perspect Biol (2015) 0.88
The budding yeast polo-like kinase Cdc5 regulates the Ndt80 branch of the meiotic recombination checkpoint pathway. Mol Biol Cell (2011) 0.88
Targeted protein depletion in Saccharomyces cerevisiae by activation of a bidirectional degron. BMC Syst Biol (2010) 0.88
Monopolin subunit Csm1 associates with MIND complex to establish monopolar attachment of sister kinetochores at meiosis I. PLoS Genet (2013) 0.85
Polo kinase Cdc5 is a central regulator of meiosis I. Proc Natl Acad Sci U S A (2013) 0.85
Genetic analysis of mlh3 mutations reveals interactions between crossover promoting factors during meiosis in baker's yeast. G3 (Bethesda) (2013) 0.84
LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. PLoS Biol (2012) 0.84
Meiosis: DDK is not just for replication. Curr Biol (2009) 0.82
Remodeling of the Rad51 DNA strand-exchange protein by the Srs2 helicase. Genetics (2013) 0.82
Male hypogonadism and germ cell loss caused by a mutation in Polo-like kinase 4. Endocrinology (2011) 0.82
Deconstructing meiosis one kinase at a time: polo pushes past pachytene. Genes Dev (2008) 0.82
Cohesin subunit Rad21L, the new kid on the block has new ideas. EMBO Rep (2011) 0.81
Differentiating the roles of microtubule-associated proteins at meiotic kinetochores during chromosome segregation. Chromosoma (2015) 0.80
Kinetochore rearrangement in meiosis II requires attachment to the spindle. Chromosoma (2005) 0.80
Mechanism of haploidy-dependent unreductional meiotic cell division in polyploid wheat. Chromosoma (2010) 0.80
Dot1-dependent histone H3K79 methylation promotes the formation of meiotic double-strand breaks in the absence of histone H3K4 methylation in budding yeast. PLoS One (2014) 0.79
Reconstruction of the kinetochore: a prelude to meiosis. Cell Div (2007) 0.79
Control of the mitotic exit network during meiosis. Mol Biol Cell (2012) 0.79
Meiosis I: when chromosomes undergo extreme makeover. Curr Opin Cell Biol (2013) 0.79
Co-segregation of yeast plasmid sisters under monopolin-directed mitosis suggests association of plasmid sisters with sister chromatids. Nucleic Acids Res (2013) 0.79
Trans-Lesion DNA Polymerases May Be Involved in Yeast Meiosis. G3 (Bethesda) (2013) 0.78
Meiotic prophase roles of Rec8 in crossover recombination and chromosome structure. Nucleic Acids Res (2016) 0.78
Interorganelle interactions and inheritance patterns of nuclei and vacuoles in budding yeast meiosis. Autophagy (2013) 0.77
Condensin suppresses recombination and regulates double-strand break processing at the repetitive ribosomal DNA array to ensure proper chromosome segregation during meiosis in budding yeast. Mol Biol Cell (2014) 0.77
Ipl1/Aurora kinase suppresses S-CDK-driven spindle formation during prophase I to ensure chromosome integrity during meiosis. PLoS One (2013) 0.77
Unique subcellular distribution of phosphorylated Plk1 (Ser137 and Thr210) in mouse oocytes during meiotic division and pPlk1(Ser137) involvement in spindle formation and REC8 cleavage. Cell Cycle (2015) 0.76
Ipl1/Aurora-B is necessary for kinetochore restructuring in meiosis I in Saccharomyces cerevisiae. Mol Biol Cell (2015) 0.76
A meiotic mystery: How sister kinetochores avoid being pulled in opposite directions during the first division. Bioessays (2015) 0.76
Monopolar attachment by Polo. Nat Cell Biol (2003) 0.75
Generation of an inducible system to express polo-like kinase, Cdc5 as TAP fusion protein during meiosis in Saccharomyces cerevisiae. 3 Biotech (2016) 0.75
Coordination of Double Strand Break Repair and Meiotic Progression in Yeast by a Mek1- Ndt80 Negative Feedback Loop. Genetics (2017) 0.75
PP2A(Cdc55)'s role in reductional chromosome segregation during achiasmate meiosis in budding yeast is independent of its FEAR function. Sci Rep (2016) 0.75
polo Is Identified as a Suppressor of bubR1 Nondisjunction in a Deficiency Screen of the Third Chromosome in Drosophila melanogaster. G3 (Bethesda) (2011) 0.75
Impact of histone H4K16 acetylation on the meiotic recombination checkpoint in Saccharomyces cerevisiae. Microb Cell (2016) 0.75
Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections. Cell (2002) 6.59
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals. Nat Methods (2008) 6.51
Natural variation in human membrane transporter genes reveals evolutionary and functional constraints. Proc Natl Acad Sci U S A (2003) 5.77
Molecular architecture of SMC proteins and the yeast cohesin complex. Mol Cell (2002) 5.36
Un ménage à quatre: the molecular biology of chromosome segregation in meiosis. Cell (2003) 4.82
Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science (2010) 4.69
DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain. Mol Cell (2004) 4.54
Chromosomal cohesin forms a ring. Cell (2003) 4.38
Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break. Curr Biol (2004) 4.35
Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I. Nature (2006) 3.81
Single-cell quantification of molecules and rates using open-source microscope-based cytometry. Nat Methods (2007) 3.77
The cohesin ring concatenates sister DNA molecules. Nature (2008) 3.58
Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells. PLoS Biol (2005) 3.33
Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity. Mol Cell (2009) 3.33
Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals. Proc Natl Acad Sci U S A (2002) 3.28
Unique and redundant roles for HOG MAPK pathway components as revealed by whole-genome expression analysis. Mol Biol Cell (2003) 2.92
Cell-type-specific TEV protease cleavage reveals cohesin functions in Drosophila neurons. Dev Cell (2008) 2.82
Structure and stability of cohesin's Smc1-kleisin interaction. Mol Cell (2004) 2.81
Control of landmark events in meiosis by the CDK Cdc28 and the meiosis-specific kinase Ime2. Genes Dev (2003) 2.79
Mapping meiotic single-strand DNA reveals a new landscape of DNA double-strand breaks in Saccharomyces cerevisiae. PLoS Biol (2007) 2.71
Monopolar attachment of sister kinetochores at meiosis I requires casein kinase 1. Cell (2006) 2.70
ATP hydrolysis is required for cohesin's association with chromosomes. Curr Biol (2003) 2.69
Tension between two kinetochores suffices for their bi-orientation on the mitotic spindle. Nature (2004) 2.64
Evidence that loading of cohesin onto chromosomes involves opening of its SMC hinge. Cell (2006) 2.58
A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation. Nature (2011) 2.58
Yeast go the whole HOG for the hyperosmotic response. Trends Genet (2002) 2.45
Cdc14 phosphatase induces rDNA condensation and resolves cohesin-independent cohesion during budding yeast anaphase. Cell (2004) 2.40
A topological interaction between cohesin rings and a circular minichromosome. Cell (2005) 2.35
Two fission yeast homologs of Drosophila Mei-S332 are required for chromosome segregation during meiosis I and II. Curr Biol (2004) 2.28
A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Mol Cell (2004) 2.27
An Smc3 acetylation cycle is essential for establishment of sister chromatid cohesion. Mol Cell (2010) 2.23
Kinetochore recruitment of two nucleolar proteins is required for homolog segregation in meiosis I. Dev Cell (2003) 2.17
Phosphorylation by cyclin B-Cdk underlies release of mitotic exit activator Cdc14 from the nucleolus. Science (2004) 2.14
Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin. Proc Natl Acad Sci U S A (2012) 2.06
Human Scc4 is required for cohesin binding to chromatin, sister-chromatid cohesion, and mitotic progression. Curr Biol (2006) 2.04
Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion. Curr Biol (2002) 2.04
Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes. Genes Dev (2010) 2.04
Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1. Proc Natl Acad Sci U S A (2003) 2.03
Meiotic chromosome synapsis-promoting proteins antagonize the anti-crossover activity of sgs1. PLoS Genet (2006) 1.98
Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita. Genes Dev (2011) 1.98
Resolution of chiasmata in oocytes requires separase-mediated proteolysis. Cell (2006) 1.96
Association of Mre11p with double-strand break sites during yeast meiosis. Mol Cell (2004) 1.95
Maintenance of cohesin at centromeres after meiosis I in budding yeast requires a kinetochore-associated protein related to MEI-S332. Curr Biol (2004) 1.93
Cohesin's concatenation of sister DNAs maintains their intertwining. Mol Cell (2011) 1.91
Sum1 and Ndt80 proteins compete for binding to middle sporulation element sequences that control meiotic gene expression. Mol Cell Biol (2003) 1.90
A direct role for cohesin in gene regulation and ecdysone response in Drosophila salivary glands. Curr Biol (2010) 1.86
Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners. Mol Cell (2003) 1.85
BLM helicase ortholog Sgs1 is a central regulator of meiotic recombination intermediate metabolism. Mol Cell (2012) 1.81
Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression. J Cell Biol (2006) 1.80
Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene. Pharmacogenetics (2003) 1.79
Novel genes required for meiotic chromosome segregation are identified by a high-throughput knockout screen in fission yeast. Curr Biol (2005) 1.76
Regulation of APC/C activity in oocytes by a Bub1-dependent spindle assembly checkpoint. Curr Biol (2009) 1.76
Cohesin's DNA exit gate is distinct from its entrance gate and is regulated by acetylation. Cell (2012) 1.75
Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei. Nat Cell Biol (2010) 1.74
Anatomy and dynamics of DNA replication fork movement in yeast telomeric regions. Mol Cell Biol (2004) 1.69
Polo-like kinase Cdc5 drives exit from pachytene during budding yeast meiosis. Genes Dev (2008) 1.66
Structure and function of the PP2A-shugoshin interaction. Mol Cell (2009) 1.66
The Khd1 protein, which has three KH RNA-binding motifs, is required for proper localization of ASH1 mRNA in yeast. EMBO J (2002) 1.62
Rec8 phosphorylation by casein kinase 1 and Cdc7-Dbf4 kinase regulates cohesin cleavage by separase during meiosis. Dev Cell (2010) 1.61
Techniques for gamma-H2AX detection. Methods Enzymol (2006) 1.61
Building and breaking bridges between sister chromatids. Bioessays (2003) 1.61
Mus81/Mms4 endonuclease and Sgs1 helicase collaborate to ensure proper recombination intermediate metabolism during meiosis. Mol Cell (2008) 1.61
A third osmosensing branch in Saccharomyces cerevisiae requires the Msb2 protein and functions in parallel with the Sho1 branch. Mol Cell Biol (2002) 1.58
Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function. Pharmacogenetics (2002) 1.57
Frequent and efficient use of the sister chromatid for DNA double-strand break repair during budding yeast meiosis. PLoS Biol (2010) 1.54
Condensin binding at distinct and specific chromosomal sites in the Saccharomyces cerevisiae genome. Mol Cell Biol (2005) 1.53
Genomic dissection of the cell-type-specification circuit in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2004) 1.52
Sister-chromatid cohesion mediated by the alternative RF-CCtf18/Dcc1/Ctf8, the helicase Chl1 and the polymerase-alpha-associated protein Ctf4 is essential for chromatid disjunction during meiosis II. J Cell Sci (2004) 1.51
Division of the nucleolus and its release of CDC14 during anaphase of meiosis I depends on separase, SPO12, and SLK19. Dev Cell (2003) 1.48
Infrequent co-conversion of markers flanking a meiotic recombination initiation site in Saccharomyces cerevisiae. Genetics (2005) 1.45
A physical assay for sister chromatid cohesion in vitro. Mol Cell (2007) 1.35
Loss of the anaphase-promoting complex in quiescent cells causes unscheduled hepatocyte proliferation. Genes Dev (2004) 1.34
The kinetochore proteins Pcs1 and Mde4 and heterochromatin are required to prevent merotelic orientation. Curr Biol (2007) 1.33
Spo13 facilitates monopolin recruitment to kinetochores and regulates maintenance of centromeric cohesion during yeast meiosis. Curr Biol (2004) 1.33
Cohesin's ATPase activity is stimulated by the C-terminal Winged-Helix domain of its kleisin subunit. Curr Biol (2006) 1.32
Construction of conditional analog-sensitive kinase alleles in the fission yeast Schizosaccharomyces pombe. Nat Protoc (2007) 1.32
Control of Shugoshin function during fission-yeast meiosis. Curr Biol (2005) 1.31
High-throughput knockout screen in fission yeast. Nat Protoc (2006) 1.30
Role of cleavage by separase of the Rec8 kleisin subunit of cohesin during mammalian meiosis I. J Cell Sci (2009) 1.24
Cohesin cleavage is insufficient for centriole disengagement in Drosophila. Curr Biol (2013) 1.21
Correlation between premeiotic DNA replication and chromatin transition at yeast recombination initiation sites. Nucleic Acids Res (2003) 1.19
Evolution of eukaryotic cell cycle regulation: stepwise addition of regulatory kinases and late advent of the CDKs. Curr Biol (2003) 1.17
Disengaging the Smc3/kleisin interface releases cohesin from Drosophila chromosomes during interphase and mitosis. EMBO J (2013) 1.16
Tandem affinity purification of functional TAP-tagged proteins from human cells. Nat Protoc (2007) 1.15
Meiotic recombination intermediates are resolved with minimal crossover formation during return-to-growth, an analogue of the mitotic cell cycle. PLoS Genet (2011) 1.13
Scaffold number in yeast signaling system sets tradeoff between system output and dynamic range. Proc Natl Acad Sci U S A (2011) 1.11
The Drosophila meiotic kleisin C(2)M functions before the meiotic divisions. Chromosoma (2004) 1.09
A REC8-dependent plant Shugoshin is required for maintenance of centromeric cohesion during meiosis and has no mitotic functions. Curr Biol (2005) 1.09
Stabilization and electrophoretic analysis of meiotic recombination intermediates in Saccharomyces cerevisiae. Methods Mol Biol (2009) 1.08
A positively charged channel within the Smc1/Smc3 hinge required for sister chromatid cohesion. EMBO J (2010) 1.06
Sgol2 provides a regulatory platform that coordinates essential cell cycle processes during meiosis I in oocytes. Elife (2013) 1.04
Both interaction surfaces within cohesin's hinge domain are essential for its stable chromosomal association. Curr Biol (2010) 1.04
Function-altering SNPs in the human multidrug transporter gene ABCB1 identified using a Saccharomyces-based assay. PLoS Genet (2007) 1.04
Pds5 promotes and protects cohesin acetylation. Proc Natl Acad Sci U S A (2013) 1.03
The Smk1p MAP kinase negatively regulates Gsc2p, a 1,3-beta-glucan synthase, during spore wall morphogenesis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2005) 1.02