Published in Circulation on May 05, 2003
Hydroethidine- and MitoSOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: another inconvenient truth. Free Radic Biol Med (2010) 2.32
Anti-inflammatory apoA-I-mimetic peptides bind oxidized lipids with much higher affinity than human apoA-I. J Lipid Res (2008) 2.27
In vitro stimulation of HDL anti-inflammatory activity and inhibition of LDL pro-inflammatory activity in the plasma of patients with end-stage renal disease by an apoA-1 mimetic peptide. Kidney Int (2009) 2.09
Effects of D-4F on vasodilation and vessel wall thickness in hypercholesterolemic LDL receptor-null and LDL receptor/apolipoprotein A-I double-knockout mice on Western diet. Circ Res (2005) 2.06
The L-4F mimetic peptide prevents insulin resistance through increased levels of HO-1, pAMPK, and pAKT in obese mice. J Lipid Res (2009) 1.48
Sickle cell disease increases high mobility group box 1: a novel mechanism of inflammation. Blood (2014) 1.44
Structure and function of HDL mimetics. Arterioscler Thromb Vasc Biol (2009) 1.40
Apolipoprotein A-I mimetic peptide helix number and helix linker influence potentially anti-atherogenic properties. J Lipid Res (2008) 1.39
HDL metabolism and activity in chronic kidney disease. Nat Rev Nephrol (2010) 1.32
Novel biological functions of high-density lipoprotein cholesterol. Circ Res (2012) 1.19
HDL as a biomarker, potential therapeutic target, and therapy. Diabetes (2009) 1.19
The 5A apolipoprotein A-I mimetic peptide displays antiinflammatory and antioxidant properties in vivo and in vitro. Arterioscler Thromb Vasc Biol (2009) 1.19
Proteomic identification of altered apolipoprotein patterns in pulmonary hypertension and vasculopathy of sickle cell disease. Blood (2008) 1.18
D-4F, an apoA-1 mimetic, decreases airway hyperresponsiveness, inflammation, and oxidative stress in a murine model of asthma. J Lipid Res (2010) 1.14
Genetic deletion of apolipoprotein A-I increases airway hyperresponsiveness, inflammation, and collagen deposition in the lung. J Lipid Res (2010) 1.12
Vascular dysfunction in a murine model of severe hemolysis. Blood (2008) 1.08
A systems biology consideration of the vasculopathy of sickle cell anemia: the need for multi-modality chemo-prophylaxsis. Cardiovasc Hematol Disord Drug Targets (2009) 1.07
Multiple indications for anti-inflammatory apolipoprotein mimetic peptides. Curr Opin Investig Drugs (2008) 1.06
Evolution of novel small-molecule therapeutics targeting sickle cell vasculopathy. JAMA (2008) 1.02
Apolipoprotein A-I mimetic peptide 4F rescues pulmonary hypertension by inducing microRNA-193-3p. Circulation (2014) 1.00
Apolipoprotein A-I and A-I mimetic peptides: a role in atherosclerosis. J Inflamm Res (2011) 1.00
HDL and endothelial protection. Br J Pharmacol (2013) 0.99
The effect of apolipoprotein mimetic peptides in inflammatory disorders other than atherosclerosis. Trends Cardiovasc Med (2008) 0.99
Biological properties of apolipoprotein a-I mimetic peptides. Curr Atheroscler Rep (2010) 0.95
Redox-dependent impairment of vascular function in sickle cell disease. Free Radic Biol Med (2007) 0.93
Anti-inflammatory and cholesterol-reducing properties of apolipoprotein mimetics: a review. J Lipid Res (2014) 0.92
Apolipoprotein A-I and serum amyloid A plasma levels are biomarkers of acute painful episodes in patients with sickle cell disease. Haematologica (2010) 0.90
HDL apolipoprotein-related peptides in the treatment of atherosclerosis and other inflammatory disorders. Curr Pharm Des (2010) 0.87
Dysfunctional high-density lipoprotein and the potential of apolipoprotein A-1 mimetic peptides to normalize the composition and function of lipoproteins. Circ J (2011) 0.87
HDL, Atherosclerosis, and Emerging Therapies. Cholesterol (2013) 0.87
New kids on the block: the emerging role of apolipoproteins in the pathogenesis and treatment of asthma. Chest (2011) 0.86
Isolated low high density lipoprotein-cholesterol (HDL-C): implications of global risk reduction. Case report and systematic scientific review. Cardiovasc Diabetol (2005) 0.86
Novel small molecule therapeutics for sickle cell disease: nitric oxide, carbon monoxide, nitrite, and apolipoprotein A-I. Hematology Am Soc Hematol Educ Program (2008) 0.84
Peptide Mimetics of Apolipoproteins Improve HDL Function. J Clin Lipidol (2007) 0.83
A novel hemoglobin-binding peptide reduces cell-free hemoglobin in murine hemolytic anemia. Am J Physiol Heart Circ Physiol (2012) 0.81
Vasculoprotective Effects of Apolipoprotein Mimetic Peptides: An Evolving Paradigm In Hdl Therapy (Vascular Disease Prevention, In Press.). Vasc Dis Prev (2009) 0.80
Pathophisiology of sickle cell disease and new drugs for the treatment. Mediterr J Hematol Infect Dis (2009) 0.80
Amelioration of nephropathy with apoA-1 mimetic peptide in apoE-deficient mice. Nephrol Dial Transplant (2010) 0.80
4F decreases IRF5 expression and activation in hearts of tight skin mice. PLoS One (2012) 0.80
Association of pro-inflammatory high-density lipoprotein cholesterol with clinical and laboratory variables in sickle cell disease. Hematology (2014) 0.79
The combination of L-4F and simvastatin stimulate cholesterol efflux and related proteins expressions to reduce atherosclerotic lesions in apoE knockout mice. Lipids Health Dis (2013) 0.78
Role of oxidized lipids in pulmonary arterial hypertension. Pulm Circ (2016) 0.77
High-density lipoprotein mimetics: promises and challenges. Biochem J (2015) 0.76
Dysregulation of ubiquitin-proteasome pathway and apolipoprotein A metabolism in sickle cell disease-related pulmonary arterial hypertension. Pulm Circ (2013) 0.76
An IRF5 Decoy Peptide Reduces Myocardial Inflammation and Fibrosis and Improves Endothelial Cell Function in Tight-Skin Mice. PLoS One (2016) 0.75
Executive summary: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 5.88
Bariatric surgery for severely overweight adolescents: concerns and recommendations. Pediatrics (2004) 5.01
Pathology of Berkeley sickle cell mice: similarities and differences with human sickle cell disease. Blood (2005) 2.37
Angiostatin inhibits coronary angiogenesis during impaired production of nitric oxide. Circulation (2002) 2.35
Mitochondrial sources of H2O2 generation play a key role in flow-mediated dilation in human coronary resistance arteries. Circ Res (2003) 2.31
Mitochondrial reactive oxygen species-mediated signaling in endothelial cells. Am J Physiol Heart Circ Physiol (2007) 2.24
Role for hydrogen peroxide in flow-induced dilation of human coronary arterioles. Circ Res (2003) 2.09
Hypoxia-induced acute lung injury in murine models of sickle cell disease. Am J Physiol Lung Cell Mol Physiol (2003) 2.08
Effects of D-4F on vasodilation and vessel wall thickness in hypercholesterolemic LDL receptor-null and LDL receptor/apolipoprotein A-I double-knockout mice on Western diet. Circ Res (2005) 2.06
Diabetes mellitus impairs vasodilation to hypoxia in human coronary arterioles: reduced activity of ATP-sensitive potassium channels. Circ Res (2003) 2.01
The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humans. J Clin Invest (2008) 1.82
Phosphorylation of threonine 497 in endothelial nitric-oxide synthase coordinates the coupling of L-arginine metabolism to efficient nitric oxide production. J Biol Chem (2003) 1.80
Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BK(Ca) channels: implications for soluble epoxide hydrolase inhibition. Am J Physiol Heart Circ Physiol (2005) 1.76
TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress. Am J Physiol Heart Circ Physiol (2009) 1.76
Effects of 5-aza-2'-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease. Blood (2003) 1.76
Measuring FMD in the brachial artery: how important is QRS gating? J Appl Physiol (1985) (2010) 1.75
Delayed hemolytic transfusion reaction/hyperhemolysis syndrome in children with sickle cell disease. Pediatrics (2003) 1.67
Coagulation activation and inflammation in sickle cell disease-associated pulmonary hypertension. Haematologica (2008) 1.67
20-hydroxyeicosatetraenoic acid causes endothelial dysfunction via eNOS uncoupling. Am J Physiol Heart Circ Physiol (2007) 1.59
The mechanism of flow-induced dilation in human adipose arterioles involves hydrogen peroxide during CAD. Am J Physiol Heart Circ Physiol (2006) 1.55
Transient receptor potential vanilloid type 4-deficient mice exhibit impaired endothelium-dependent relaxation induced by acetylcholine in vitro and in vivo. Hypertension (2009) 1.51
Variation in treatment of pediatric spleen injury at trauma centers versus nontrauma centers: a call for dissemination of American Pediatric Surgical Association benchmarks and guidelines. J Am Coll Surg (2005) 1.50
H2O2 is the transferrable factor mediating flow-induced dilation in human coronary arterioles. Circ Res (2011) 1.49
Peroxynitrite inhibits Ca2+-activated K+ channel activity in smooth muscle of human coronary arterioles. Circ Res (2002) 1.49
Intestinal alkaline phosphatase prevents the systemic inflammatory response associated with necrotizing enterocolitis. J Surg Res (2012) 1.48
Outcomes and delivery of care in pediatric injury. J Pediatr Surg (2006) 1.45
Acquired microvascular dysfunction in inflammatory bowel disease: Loss of nitric oxide-mediated vasodilation. Gastroenterology (2003) 1.44
Altered mitochondrial membrane potential, mass, and morphology in the mononuclear cells of humans with type 2 diabetes. Transl Res (2010) 1.40
Firearm injuries and children: a policy statement of the American Pediatric Surgical Association. J Am Coll Surg (2013) 1.39
Patients with sickle cell disease have increased sensitivity to cold and heat. Am J Hematol (2012) 1.38
First, do no harm: less training ≠ quality care. Am J Crit Care (2012) 1.38
Hydrogen peroxide inhibits cytochrome p450 epoxygenases: interaction between two endothelium-derived hyperpolarizing factors. Circ Res (2007) 1.36
Variation in hospitalizations and hospital length of stay in children with vaso-occlusive crises in sickle cell disease. Pediatr Blood Cancer (2005) 1.35
Decreased association of HSP90 impairs endothelial nitric oxide synthase in fetal lambs with persistent pulmonary hypertension. Am J Physiol Heart Circ Physiol (2003) 1.34
Effects of D-4F on vasodilation, oxidative stress, angiostatin, myocardial inflammation, and angiogenic potential in tight-skin mice. Am J Physiol Heart Circ Physiol (2007) 1.32
Oxidative stress and potassium channel function. Clin Exp Pharmacol Physiol (2002) 1.28
Beyond vasodilatation: non-vasomotor roles of epoxyeicosatrienoic acids in the cardiovascular system. Trends Pharmacol Sci (2006) 1.28
Pulmonary hypertension and NO in sickle cell. Blood (2010) 1.28
Erythropoietin protects the infant heart against ischemia-reperfusion injury by triggering multiple signaling pathways. Basic Res Cardiol (2004) 1.27
H2O2-induced dilation in human coronary arterioles: role of protein kinase G dimerization and large-conductance Ca2+-activated K+ channel activation. Circ Res (2011) 1.27
Protective effects of epoxyeicosatrienoic acids on human endothelial cells from the pulmonary and coronary vasculature. Am J Physiol Heart Circ Physiol (2006) 1.26
Regulation of endothelial function by mitochondrial reactive oxygen species. Antioxid Redox Signal (2011) 1.25
Mechanisms of activation of eNOS by 20-HETE and VEGF in bovine pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol (2006) 1.25
The vascular contribution in the pathogenesis of inflammatory bowel disease. Am J Physiol Heart Circ Physiol (2003) 1.23
MCP-1 contributes to arteriovenous fistula failure. J Am Soc Nephrol (2010) 1.23
Mechanism of vasodilation to adenosine in coronary arterioles from patients with heart disease. Am J Physiol Heart Circ Physiol (2005) 1.22
Activation of endothelial TRPV4 channels mediates flow-induced dilation in human coronary arterioles: role of Ca2+ entry and mitochondrial ROS signaling. Am J Physiol Heart Circ Physiol (2011) 1.20
Acute exposure to low glucose rapidly induces endothelial dysfunction and mitochondrial oxidative stress: role for AMP kinase. Arterioscler Thromb Vasc Biol (2011) 1.20
L-4F, an apolipoprotein A-1 mimetic, restores nitric oxide and superoxide anion balance in low-density lipoprotein-treated endothelial cells. Circulation (2003) 1.18
Clinical and hematologic benefits of partial splenectomy for congenital hemolytic anemias in children. Ann Surg (2003) 1.18
A heat shock protein 90 binding domain in endothelial nitric-oxide synthase influences enzyme function. J Biol Chem (2007) 1.18
The effect of exertional hypertension evoked by weight lifting on vascular endothelial function. J Am Coll Cardiol (2006) 1.17
Renal hemodynamic, inflammatory, and apoptotic responses to lipopolysaccharide in HO-1-/- mice. Am J Pathol (2007) 1.16
Characterization of a model of an arteriovenous fistula in the rat: the effect of L-NAME. Am J Pathol (2010) 1.15
Human microvascular dysfunction and apoptotic injury induced by AL amyloidosis light chain proteins. Am J Physiol Heart Circ Physiol (2011) 1.14
Elevated glucose impairs cAMP-mediated dilation by reducing Kv channel activity in rat small coronary smooth muscle cells. Am J Physiol Heart Circ Physiol (2003) 1.14
Chronic hypoxia increases endothelial nitric oxide synthase generation of nitric oxide by increasing heat shock protein 90 association and serine phosphorylation. Circ Res (2002) 1.14
Systemic and microvascular oxidative stress induced by light chain amyloidosis. Int J Cardiol (2009) 1.13
Renal upregulation of HO-1 reduces albumin-driven MCP-1 production: implications for chronic kidney disease. Am J Physiol Renal Physiol (2006) 1.12
Acute cardioprotective effects of erythropoietin in infant rabbits are mediated by activation of protein kinases and potassium channels. Basic Res Cardiol (2004) 1.12
Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Proteomics (2008) 1.12
Histopathology of experimentally induced asthma in a murine model of sickle cell disease. Blood (2008) 1.12
Resistance and aerobic exercise protects against acute endothelial impairment induced by a single exposure to hypertension during exertion. J Appl Physiol (1985) (2011) 1.12
Genetic deletion of apolipoprotein A-I increases airway hyperresponsiveness, inflammation, and collagen deposition in the lung. J Lipid Res (2010) 1.12
ROS-induced ROS release in vascular biology: redox-redox signaling. Am J Physiol Heart Circ Physiol (2011) 1.11
Traumatic injury and children: a national assessment. J Trauma (2007) 1.10
Are statewide trauma registries comparable? Reaching for a national trauma dataset. Acad Emerg Med (2006) 1.10
BN phenome: detailed characterization of the cardiovascular, renal, and pulmonary systems of the sequenced rat. Physiol Genomics (2006) 1.09
A practical algorithmic approach to the diagnosis and management of solitary pulmonary nodules: part 1: radiologic characteristics and imaging modalities. Chest (2013) 1.09
Vascular dysfunction in a murine model of severe hemolysis. Blood (2008) 1.08
Diversity in mechanisms of endothelium-dependent vasodilation in health and disease. Microcirculation (2013) 1.07
Endothelium-derived microparticles induce endothelial dysfunction and acute lung injury. Shock (2006) 1.06
Mechanism of dilation to reactive oxygen species in human coronary arterioles. Am J Physiol Heart Circ Physiol (2003) 1.06
Thymic transplantation for complete DiGeorge syndrome: medical and surgical considerations. J Pediatr Surg (2004) 1.06