Published in Am J Physiol Heart Circ Physiol on May 11, 2007
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The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases. Cell (2007) 6.04
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New nomenclature for chromatin-modifying enzymes. Cell (2007) 5.34
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Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells. Mol Cell (2011) 4.89
Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression. Nature (2007) 4.49
Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans. Nature (2011) 4.41
RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Nature (2007) 4.35
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Yin Yang 1 is a negative regulator of p53. Cell (2004) 3.24
The phosphothreonine lyase activity of a bacterial type III effector family. Science (2007) 3.18
Yin Yang 1 is a critical regulator of B-cell development. Genes Dev (2007) 3.06
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Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases. Nat Struct Mol Biol (2009) 2.87
SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation. Nature (2008) 2.84
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Identification of a Ctcf cofactor, Yy1, for the X chromosome binary switch. Mol Cell (2007) 2.69
JAK2V617F-mediated phosphorylation of PRMT5 downregulates its methyltransferase activity and promotes myeloproliferation. Cancer Cell (2011) 2.56
Prolyl 4-hydroxylation regulates Argonaute 2 stability. Nature (2008) 2.51
Essential dosage-dependent functions of the transcription factor yin yang 1 in late embryonic development and cell cycle progression. Mol Cell Biol (2006) 2.48
Lid2 is required for coordinating H3K4 and H3K9 methylation of heterochromatin and euchromatin. Cell (2008) 2.42
The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation. Neuron (2007) 2.38
CDK-9/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C. elegans embryo. Genes Dev (2002) 2.36
Mutations in CHD7, encoding a chromatin-remodeling protein, cause idiopathic hypogonadotropic hypogonadism and Kallmann syndrome. Am J Hum Genet (2008) 2.33
Impact of Clostridium difficile on inflammatory bowel disease. Clin Gastroenterol Hepatol (2007) 2.20
Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development. Nature (2010) 2.20
ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome. Nat Struct Mol Biol (2011) 2.18
Reconstituted membrane fusion requires regulatory lipids, SNAREs and synergistic SNARE chaperones. EMBO J (2008) 2.16
Patrol detection for replica attacks on wireless sensor networks. Sensors (Basel) (2011) 2.14
Hypoxia-induced acute lung injury in murine models of sickle cell disease. Am J Physiol Lung Cell Mol Physiol (2003) 2.08
Effects of D-4F on vasodilation and vessel wall thickness in hypercholesterolemic LDL receptor-null and LDL receptor/apolipoprotein A-I double-knockout mice on Western diet. Circ Res (2005) 2.06
The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression. Mol Cell Biol (2010) 1.96
CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation. Mol Cell (2008) 1.94
Developmental roles of the histone lysine demethylases. Development (2009) 1.92
Measuring disease activity and functional status in patients with scleroderma and Raynaud's phenomenon. Arthritis Rheum (2002) 1.91
Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis. Aging Cell (2003) 1.88
S. pombe LSD1 homologs regulate heterochromatin propagation and euchromatic gene transcription. Mol Cell (2007) 1.84
Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins. Nat Struct Mol Biol (2009) 1.81
Phosphorylation of threonine 497 in endothelial nitric-oxide synthase coordinates the coupling of L-arginine metabolism to efficient nitric oxide production. J Biol Chem (2003) 1.80
YY1 functions with INO80 to activate transcription. Nat Struct Mol Biol (2007) 1.79
Technical factors related to the incidence of adjacent superior segment facet joint violation after transpedicular instrumentation in the lumbar spine. Eur Spine J (2008) 1.75
Structural basis of the recognition of a methylated histone tail by JMJD2A. Proc Natl Acad Sci U S A (2007) 1.74
Phosphorylation by the beta-catenin/MAPK complex promotes 14-3-3-mediated nuclear export of TCF/POP-1 in signal-responsive cells in C. elegans. Cell (2004) 1.73
Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation. Mol Cell (2010) 1.73
Ineffectiveness of histone deacetylase inhibitors to induce apoptosis involves the transcriptional activation of NF-kappa B through the Akt pathway. J Biol Chem (2003) 1.73
A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair. Nat Struct Mol Biol (2007) 1.68
Relation of low vitamin D to nonvalvular persistent atrial fibrillation in Chinese patients. Ann Noninvasive Electrocardiol (2013) 1.66
Eosinophilic esophagitis in adults: an emerging problem with unique esophageal features. Gastrointest Endosc (2004) 1.65
Emerging roles for chromatin as a signal integration and storage platform. Nat Rev Mol Cell Biol (2013) 1.65
Study on the tongue manifestations for the blood-stasis and toxin syndrome in the stable patients of coronary heart disease. Chin J Integr Med (2011) 1.65
Translocations disrupting PHF21A in the Potocki-Shaffer-syndrome region are associated with intellectual disability and craniofacial anomalies. Am J Hum Genet (2012) 1.64
The histone demethylase UTX enables RB-dependent cell fate control. Genes Dev (2010) 1.62
20-hydroxyeicosatetraenoic acid causes endothelial dysfunction via eNOS uncoupling. Am J Physiol Heart Circ Physiol (2007) 1.59
NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression. Proc Natl Acad Sci U S A (2006) 1.59
Par-4 links dopamine signaling and depression. Cell (2005) 1.58
Characterization of human cardiac mitochondrial ATP-sensitive potassium channel and its regulation by phorbol ester in vitro. Am J Physiol Heart Circ Physiol (2005) 1.57
Determination of oleanolic acid and ursolic acid contents in Ziziphora clinopodioides Lam. by HPLC method. Pharmacogn Mag (2010) 1.57
Photodynamic characterization and in vitro application of methylene blue-containing nanoparticle platforms. Photochem Photobiol (2005) 1.56
Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire. Immunity (2013) 1.56
L-4F, an apolipoprotein A-1 mimetic, dramatically improves vasodilation in hypercholesterolemia and sickle cell disease. Circulation (2003) 1.53
Age-associated difference in circadian sleep-wake and rest-activity rhythms. Physiol Behav (2002) 1.53
Human thrombopoietin reduces myocardial infarct size, apoptosis, and stunning following ischaemia/reperfusion in rats. Cardiovasc Res (2007) 1.52
Selective tumor hypoxia targeting by hypoxia-activated prodrug TH-302 inhibits tumor growth in preclinical models of cancer. Clin Cancer Res (2011) 1.51
Differential contributions of Caenorhabditis elegans histone deacetylases to huntingtin polyglutamine toxicity. J Neurosci (2006) 1.51
DNA unwinding by ASCC3 helicase is coupled to ALKBH3-dependent DNA alkylation repair and cancer cell proliferation. Mol Cell (2011) 1.51
Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature (2011) 1.50
Variation in treatment of pediatric spleen injury at trauma centers versus nontrauma centers: a call for dissemination of American Pediatric Surgical Association benchmarks and guidelines. J Am Coll Surg (2005) 1.50
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. Science (2011) 1.49
Intestinal alkaline phosphatase prevents the systemic inflammatory response associated with necrotizing enterocolitis. J Surg Res (2012) 1.48
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A Legionella type IV effector activates the NF-kappaB pathway by phosphorylating the IkappaB family of inhibitors. Proc Natl Acad Sci U S A (2009) 1.48
The multifunctional human p100 protein 'hooks' methylated ligands. Nat Struct Mol Biol (2007) 1.46
Endoplasmic reticulum stress induction of the Grp78/BiP promoter: activating mechanisms mediated by YY1 and its interactive chromatin modifiers. Mol Cell Biol (2005) 1.46
Outcomes and delivery of care in pediatric injury. J Pediatr Surg (2006) 1.45
The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation. Genes Dev (2012) 1.43