Muscle hypertrophy, hormonal adaptations and strength development during strength training in strength-trained and untrained men.

PubWeight™: 1.15‹?› | Rank: Top 10%

🔗 View Article (PMID 12734759)

Published in Eur J Appl Physiol on May 07, 2003

Authors

Juha P Ahtiainen1, Arto Pakarinen, Markku Alen, William J Kraemer, Keijo Häkkinen

Author Affiliations

1: Neuromuscular Research Center and Department of Biology of Physical Activity, University of Jyväskylä, P.O. Box 35, 40014 Jyväskylä, Finland. ahtiainen@sport.jyu.fi

Articles citing this

Physiological elevation of endogenous hormones results in superior strength training adaptation. Eur J Appl Physiol (2011) 1.68

Effects of vibration and resistance training on neuromuscular and hormonal measures. Eur J Appl Physiol (2006) 1.13

Muscular and systemic correlates of resistance training-induced muscle hypertrophy. PLoS One (2013) 1.05

Independent and combined effects of liquid carbohydrate/essential amino acid ingestion on hormonal and muscular adaptations following resistance training in untrained men. Eur J Appl Physiol (2006) 1.05

The effects of 12 weeks of beta-hydroxy-beta-methylbutyrate free acid supplementation on muscle mass, strength, and power in resistance-trained individuals: a randomized, double-blind, placebo-controlled study. Eur J Appl Physiol (2014) 1.02

Cytokine and hormone responses to resistance training. Eur J Appl Physiol (2009) 1.02

Hypertrophy with unilateral resistance exercise occurs without increases in endogenous anabolic hormone concentration. Eur J Appl Physiol (2006) 0.96

Associations of exercise-induced hormone profiles and gains in strength and hypertrophy in a large cohort after weight training. Eur J Appl Physiol (2011) 0.92

Effects of strength training with eccentric overload on muscle adaptation in male athletes. Eur J Appl Physiol (2009) 0.90

Circadian rhythms in exercise performance: implications for hormonal and muscular adaptation. J Sports Sci Med (2011) 0.87

Suppression of testosterone does not blunt mRNA expression of myoD, myogenin, IGF, myostatin or androgen receptor post strength training in humans. J Physiol (2006) 0.85

International Society of Sports Nutrition Position Stand: beta-hydroxy-beta-methylbutyrate (HMB). J Int Soc Sports Nutr (2013) 0.85

What is the best moment to apply phototherapy when associated to a strength training program? A randomized, double-blinded, placebo-controlled trial : Phototherapy in association to strength training. Lasers Med Sci (2016) 0.84

Motor performance changes induced by muscle vibration. Eur J Appl Physiol (2006) 0.84

Intramuscular anabolic signaling and endocrine response following high volume and high intensity resistance exercise protocols in trained men. Physiol Rep (2015) 0.84

Pea proteins oral supplementation promotes muscle thickness gains during resistance training: a double-blind, randomized, Placebo-controlled clinical trial vs. Whey protein. J Int Soc Sports Nutr (2015) 0.81

Effect of protein source and resistance training on body composition and sex hormones. J Int Soc Sports Nutr (2007) 0.81

Acute and cumulative effects of focused high-frequency vibrations on the endocrine system and muscle strength. Eur J Appl Physiol (2010) 0.81

Effects of soluble milk protein or casein supplementation on muscle fatigue following resistance training program: a randomized, double-blind, and placebo-controlled study. J Int Soc Sports Nutr (2014) 0.80

Effects of whole body vibration training on body composition, skeletal muscle strength, and cardiovascular health. J Exerc Rehabil (2015) 0.80

Greater Strength Gains after Training with Accentuated Eccentric than Traditional Isoinertial Loads in Already Strength-Trained Men. Front Physiol (2016) 0.80

Skeletal muscle homeostasis and plasticity in youth and ageing: impact of nutrition and exercise. Acta Physiol (Oxf) (2015) 0.79

Neuromuscular adaptations during combined strength and endurance training in endurance runners: maximal versus explosive strength training or a mix of both. Eur J Appl Physiol (2012) 0.79

Effects of electromyostimulation on muscle and bone in men with acute traumatic spinal cord injury: A randomized clinical trial. J Spinal Cord Med (2013) 0.79

Acute hormonal and force responses to combined strength and endurance loadings in men and women: the "order effect". PLoS One (2013) 0.79

Effect of resistance training on C-reactive protein, blood glucose and lipid profile in older women with differing levels of RT experience. Age (Dordr) (2015) 0.78

Prior sprint cycling did not enhance training adaptation, but resting salivary hormones were related to workout power and strength. Eur J Appl Physiol (2009) 0.78

Time-course response in serum markers of bone turnover to a single-bout of electrical stimulation in patients with recent spinal cord injury. Eur J Appl Physiol (2012) 0.78

Changes of Serum Adiponectin and Testosterone Concentrations Following Twelve Weeks Resistance Training in Obese Young Men. Asian J Sports Med (2015) 0.77

Three and six grams supplementation of d-aspartic acid in resistance trained men. J Int Soc Sports Nutr (2015) 0.77

Comparison of the effects of two resistance training regimens on muscular and bone responses in premenopausal women. Osteoporos Int (2010) 0.77

Maximal strength, power, and aerobic endurance adaptations to concurrent strength and sprint interval training. Eur J Appl Physiol (2014) 0.77

Endocrine response to acute resistance exercise in obese versus lean physically active men. Eur J Appl Physiol (2015) 0.76

Anatomical and neuromuscular variables strongly predict maximum knee extension torque in healthy men. Eur J Appl Physiol (2016) 0.76

Role of hormones and blood lipids in the pathogenesis of acne vulgaris in non-obese, non-hirsute females. Indian Dermatol Online J (2014) 0.75

Clinical applications of vibration therapy in orthopaedic practice. Muscles Ligaments Tendons J (2016) 0.75

CURRENT CONCEPTS OF MUSCLE AND TENDON ADAPTATION TO STRENGTH AND CONDITIONING. Int J Sports Phys Ther (2015) 0.75

The Differential Hormonal Milieu of Morning versus Evening May Have an Impact on Muscle Hypertrophic Potential. PLoS One (2016) 0.75

Physiological and Neural Adaptations to Eccentric Exercise: Mechanisms and Considerations for Training. Biomed Res Int (2015) 0.75

Acute elevations in serum hormones are attenuated after chronic training with traditional isoinertial but not accentuated eccentric loads in strength-trained men. Physiol Rep (2017) 0.75

Effect of tendon vibration during wide-pulse neuromuscular electrical stimulation (NMES) on the decline and recovery of muscle force. BMC Neurol (2017) 0.75

Resistance training status modifies inflammatory response to explosive and hypertrophic resistance exercise bouts. J Physiol Biochem (2017) 0.75

The order effect of combined endurance and strength loadings on force and hormone responses: effects of prolonged training. Eur J Appl Physiol (2014) 0.75

Crescent pyramid and drop-set systems do not promote greater strength gains, muscle hypertrophy, and changes on muscle architecture compared with traditional resistance training in well-trained men. Eur J Appl Physiol (2017) 0.75

Comparison of Periodized and Non-Periodized Resistance Training on Maximal Strength: A Meta-Analysis. Sports Med (2017) 0.75

Articles cited by this

The assessment of the amount of fat in the human body from measurements of skinfold thickness. Br J Nutr (1967) 10.30

Neural factors versus hypertrophy in the time course of muscle strength gain. Am J Phys Med (1979) 2.86

Testosterone secretion and metabolism in male senescence. J Clin Endocrinol Metab (1972) 2.29

A mechanism for increased contractile strength of human pennate muscle in response to strength training: changes in muscle architecture. J Physiol (2001) 1.89

Skeletal muscle adaptations during early phase of heavy-resistance training in men and women. J Appl Physiol (1985) (1994) 1.59

Compatibility of high-intensity strength and endurance training on hormonal and skeletal muscle adaptations. J Appl Physiol (1985) (1995) 1.46

Cardiovascular, ventilatory and catecholamine responses to maximal dynamic exercise in partially curarized man. J Physiol (1987) 1.45

Hormonal and growth factor responses to heavy resistance exercise protocols. J Appl Physiol (1985) (1990) 1.31

Physiologic responses to heavy-resistance exercise with very short rest periods. Int J Sports Med (1987) 1.17

Role of motor center activity for hormonal changes and substrate mobilization in humans. Am J Physiol (1987) 1.14

Effects of heavy-resistance training on hormonal response patterns in younger vs. older men. J Appl Physiol (1985) (1999) 1.13

Selective muscle hypertrophy, changes in EMG and force, and serum hormones during strength training in older women. J Appl Physiol (1985) (2001) 1.10

Acute and chronic hormonal responses to resistance training designed to promote muscle hypertrophy. Can J Appl Physiol (1999) 1.10

Overtraining in athletes. An update. Sports Med (1991) 1.09

Acute hormonal responses to two different fatiguing heavy-resistance protocols in male athletes. J Appl Physiol (1985) (1993) 1.06

Basal concentrations and acute responses of serum hormones and strength development during heavy resistance training in middle-aged and elderly men and women. J Gerontol A Biol Sci Med Sci (2000) 1.06

Endogenous anabolic hormonal and growth factor responses to heavy resistance exercise in males and females. Int J Sports Med (1991) 1.04

Neuromuscular and hormonal adaptations in athletes to strength training in two years. J Appl Physiol (1985) (1988) 1.02

Hormonal responses of multiset versus single-set heavy-resistance exercise protocols. Can J Appl Physiol (1997) 1.00

Androgens, estrogens, and sex hormone-binding globulin in middle-aged men. J Clin Endocrinol Metab (1990) 0.94

Biochemical adaptation of human skeletal muscle to heavy resistance training and immobilization. J Appl Physiol Respir Environ Exerc Physiol (1977) 0.94

Changes in hormonal concentrations after different heavy-resistance exercise protocols in women. J Appl Physiol (1985) (1993) 0.90

Hormonal and metabolic responses to exercise in humans: effect of sensory nervous blockade. Am J Physiol (1989) 0.89

Effects of endurance exercise on free testosterone concentration and the binding affinity of sex hormone binding globulin (SHBG). Int J Sports Med (1998) 0.89

Relationships between training volume, physical performance capacity, and serum hormone concentrations during prolonged training in elite weight lifters. Int J Sports Med (1987) 0.89

Characteristics of circulating growth hormone in women after acute heavy resistance exercise. Am J Physiol Endocrinol Metab (2001) 0.88

Acute hormonal responses in elite junior weightlifters. Int J Sports Med (1992) 0.86

Lactate and the effects of exercise on testosterone secretion: evidence for the involvement of a cAMP-mediated mechanism. Med Sci Sports Exerc (1997) 0.85

Reproductive hormone increases in response to acute exercise in men. Med Sci Sports Exerc (1986) 0.83

Effects of progressive resistance training on growth hormone and testosterone levels in young and elderly subjects. Mech Ageing Dev (1989) 0.83

Successive time courses of strength development and steroid hormone responses to heavy-resistance training. J Appl Physiol (1985) (1994) 0.83

Acute hormonal responses to heavy resistance exercise in younger and older men. Eur J Appl Physiol Occup Physiol (1998) 0.82

Effect of acid-base balance on the growth hormone response to acute high-intensity cycle exercise. J Appl Physiol (1985) (1994) 0.81

Glucocorticoids in metabolic control during exercise: glycogen metabolism. J Sports Med Phys Fitness (1994) 0.79

Neuromuscular fatigue in males and females during strenuous heavy resistance loading. Electromyogr Clin Neurophysiol (1994) 0.77

Testosterone response to exercise during blockade and stimulation of adrenergic receptors in man. Horm Res (1981) 0.76

The effect of acute exercise on the serum levels of testosterone and luteinizing (LH) hormone in human male athletes. J Sports Med Phys Fitness (1980) 0.75

Articles by these authors

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48

American College of Sports Medicine position stand. Progression models in resistance training for healthy adults. Med Sci Sports Exerc (2002) 4.33

Muscular adaptations in response to three different resistance-training regimens: specificity of repetition maximum training zones. Eur J Appl Physiol (2002) 2.08

Youth resistance training: updated position statement paper from the national strength and conditioning association. J Strength Cond Res (2009) 1.90

Adverse metabolic response to regular exercise: is it a rare or common occurrence? PLoS One (2012) 1.84

Interexaminer reliability of low back pain assessment using the McKenzie method. Spine (Phila Pa 1976) (2002) 1.70

Serum insulin and leptin levels in valproate-associated obesity. Epilepsia (2002) 1.60

Relationship of sex hormones to bone geometric properties and mineral density in early pubertal girls. J Clin Endocrinol Metab (2004) 1.57

Carbohydrate restriction has a more favorable impact on the metabolic syndrome than a low fat diet. Lipids (2008) 1.57

Association of low 25-hydroxyvitamin D concentrations with elevated parathyroid hormone concentrations and low cortical bone density in early pubertal and prepubertal Finnish girls. Am J Clin Nutr (2003) 1.55

Preoperative predictors for postoperative clinical outcome in lumbar spinal stenosis: systematic review. Spine (Phila Pa 1976) (2006) 1.54

Foot strike patterns of runners at the 15-km point during an elite-level half marathon. J Strength Cond Res (2007) 1.51

Serum osteocalcin is not associated with glucose but is inversely associated with leptin across generations of nondiabetic women. J Clin Endocrinol Metab (2012) 1.49

Are skeletal muscle FNDC5 gene expression and irisin release regulated by exercise and related to health? J Physiol (2013) 1.47

Improving cardiovascular fitness by strength or endurance training in women aged 76-78 years. A population-based, randomized controlled trial. Age Ageing (2002) 1.46

Comparison of low fat and low carbohydrate diets on circulating fatty acid composition and markers of inflammation. Lipids (2007) 1.45

Effects of exercise at different times on postprandial lipemia and endothelial function. Med Sci Sports Exerc (2008) 1.42

Body composition and hormonal responses to a carbohydrate-restricted diet. Metabolism (2002) 1.39

Aging, muscle fiber type, and contractile function in sprint-trained athletes. J Appl Physiol (1985) (2006) 1.34

Acute and long-term effects of resistance exercise with or without protein ingestion on muscle hypertrophy and gene expression. Amino Acids (2008) 1.31

Physical fitness profiles in young Finnish men during the years 1975-2004. Med Sci Sports Exerc (2006) 1.30

A ketogenic diet favorably affects serum biomarkers for cardiovascular disease in normal-weight men. J Nutr (2002) 1.30

Heritability of maximal isometric muscle strength in older female twins. J Appl Physiol (1985) (2003) 1.27

Testosterone physiology in resistance exercise and training: the up-stream regulatory elements. Sports Med (2010) 1.25

Evaluation of a lower-body compression garment. J Sports Sci (2003) 1.23

Performance and physiologic adaptations to resistance training. Am J Phys Med Rehabil (2002) 1.22

Determining variables of plyometric training for improving vertical jump height performance: a meta-analysis. J Strength Cond Res (2009) 1.21

Relationship between the number of repetitions and selected percentages of one repetition maximum in free weight exercises in trained and untrained men. J Strength Cond Res (2006) 1.20

Resistance exercise biology: manipulation of resistance exercise programme variables determines the responses of cellular and molecular signalling pathways. Sports Med (2008) 1.19

Determination of functional strength imbalance of the lower extremities. J Strength Cond Res (2006) 1.16

Differential effects of strength training leading to failure versus not to failure on hormonal responses, strength, and muscle power gains. J Appl Physiol (1985) (2006) 1.16

Individual responses to combined endurance and strength training in older adults. Med Sci Sports Exerc (2011) 1.15

Influence of exercise mode and osteogenic index on bone biomarker responses during short-term physical training. Bone (2009) 1.15

Position statement on youth resistance training: the 2014 International Consensus. Br J Sports Med (2013) 1.15

Very low-carbohydrate and low-fat diets affect fasting lipids and postprandial lipemia differently in overweight men. J Nutr (2004) 1.15

Changes in dynamic exercise performance following a sequence of preconditioning isometric muscle actions. J Strength Cond Res (2003) 1.15

Effects of long-term training specificity on maximal strength and power of the upper and lower extremities in athletes from different sports. Eur J Appl Physiol (2002) 1.11

Hydration and muscular performance: does fluid balance affect strength, power and high-intensity endurance? Sports Med (2007) 1.11

Comparison of a very low-carbohydrate and low-fat diet on fasting lipids, LDL subclasses, insulin resistance, and postprandial lipemic responses in overweight women. J Am Coll Nutr (2004) 1.11

Life events and change in leisure time physical activity: a systematic review. Sports Med (2012) 1.10

Panoramic ultrasonography is a valid method to measure changes in skeletal muscle cross-sectional area. Eur J Appl Physiol (2009) 1.08

Comparison of methods for assessing body composition changes during weight loss. Med Sci Sports Exerc (2002) 1.08

Metabolic syndrome and the progression of carotid intima-media thickness in elderly women. Arch Intern Med (2006) 1.08

Acute heavy-resistance exercise-induced pain and neuromuscular fatigue in elderly women with fibromyalgia and in healthy controls: effects of strength training. Arthritis Rheum (2006) 1.07

An isoenergetic very low carbohydrate diet improves serum HDL cholesterol and triacylglycerol concentrations, the total cholesterol to HDL cholesterol ratio and postprandial pipemic responses compared with a low fat diet in normal weight, normolipidemic women. J Nutr (2003) 1.06

Mixed-methods resistance training increases power and strength of young and older men. Med Sci Sports Exerc (2002) 1.06

Histological and molecular analysis of the biceps tendon long head post-tenotomy. J Orthop Res (2009) 1.06

Neural factors account for strength decrements observed after short-term muscle unloading. Am J Physiol Regul Integr Comp Physiol (2002) 1.04

The effects of ten weeks of lower-body unstable surface training on markers of athletic performance. J Strength Cond Res (2007) 1.04

Reliability of performance measurements derived from ground reaction force data during countermovement jump and the influence of sampling frequency. J Strength Cond Res (2009) 1.04

Association of physical fitness with health-related quality of life in Finnish young men. Health Qual Life Outcomes (2010) 1.03

Once weekly combined resistance and cardiovascular training in healthy older men. Med Sci Sports Exerc (2004) 1.03

Maximal power at different percentages of one repetition maximum: influence of resistance and gender. J Strength Cond Res (2007) 1.02

Effects of strength training on muscle strength characteristics, functional capabilities, and balance in middle-aged and older women. J Strength Cond Res (2006) 1.02

Cytokine and hormone responses to resistance training. Eur J Appl Physiol (2009) 1.02

Consortium for Health and Military Performance and American College of Sports Medicine consensus paper on extreme conditioning programs in military personnel. Curr Sports Med Rep (2011) 1.02

Differences in muscle and adipose tissue gene expression and cardio-metabolic risk factors in the members of physical activity discordant twin pairs. PLoS One (2010) 1.02

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. Hum Mol Genet (2014) 1.02

Changes in exercise performance and hormonal concentrations over a big ten soccer season in starters and nonstarters. J Strength Cond Res (2004) 1.02

Biomechanical and skeletal muscle determinants of maximum running speed with aging. Med Sci Sports Exerc (2009) 1.01

Effect of hydration state on strength, power, and resistance exercise performance. Med Sci Sports Exerc (2007) 1.01

Body composition, fitness, and metabolic health during strength and endurance training and their combination in middle-aged and older women. Eur J Appl Physiol (2009) 0.99

Comparison between different off-season resistance training programs in Division III American college football players. J Strength Cond Res (2009) 0.99

Whey protein supplementation during resistance training augments lean body mass. J Am Coll Nutr (2013) 0.98

Effects of combined resistance and cardiovascular training on strength, power, muscle cross-sectional area, and endurance markers in middle-aged men. Eur J Appl Physiol (2004) 0.97

Thermoregulatory responses and hydration practices in heat-acclimatized adolescents during preseason high school football. J Athl Train (2010) 0.97

Postexercise myostatin and activin IIb mRNA levels: effects of strength training. Med Sci Sports Exerc (2007) 0.96

Effects of amino acids supplement on physiological adaptations to resistance training. Med Sci Sports Exerc (2009) 0.96

Improvements of muscle strength predicted benefits in HRQOL and postural balance in women with fibromyalgia: an 8-month randomized controlled trial. Rheumatology (Oxford) (2009) 0.96

Limited effect of dietary saturated fat on plasma saturated fat in the context of a low carbohydrate diet. Lipids (2010) 0.96

Aquatic training and detraining on fitness and quality of life in fibromyalgia. Med Sci Sports Exerc (2007) 0.96

Orthopaedic manual therapy, McKenzie method or advice only for low back pain in working adults: a randomized controlled trial with one year follow-up. J Rehabil Med (2008) 0.96

Muscle activity and inactivity periods during normal daily life. PLoS One (2013) 0.96

Insulin-related metabolic changes during treatment with valproate in patients with epilepsy. Epilepsy Behav (2006) 0.95

L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress. Am J Physiol Endocrinol Metab (2002) 0.95

Creatine supplementation improves muscular performance in older men. Med Sci Sports Exerc (2002) 0.95

Heart rate dynamics after combined endurance and strength training in older men. Med Sci Sports Exerc (2009) 0.95

The effects of amino acid supplementation on hormonal responses to resistance training overreaching. Metabolism (2006) 0.95

Strength and power profiles of the lower and upper extremities in master throwers at different ages. J Strength Cond Res (2007) 0.95

Fatigue in a simulated cross-country skiing sprint competition. J Sports Sci (2009) 0.93

Performance, biochemical, and endocrine changes during a competitive football game. Med Sci Sports Exerc (2002) 0.93

Changes in height, body weight, and body composition in American football players from 1942 to 2011. J Strength Cond Res (2013) 0.93

Biological constraints that limit compensation of a common skeletal trait variant lead to inequivalence of tibial function among healthy young adults. J Bone Miner Res (2011) 0.93

The effects of creatine supplementation on muscular performance and body composition responses to short-term resistance training overreaching. Eur J Appl Physiol (2003) 0.93

Caffeine use in sports: considerations for the athlete. J Strength Cond Res (2008) 0.93

Influence of exercise order in a resistance-training exercise session. J Strength Cond Res (2006) 0.92

Serum metabolic profiles in overweight and obese women with and without metabolic syndrome. Diabetol Metab Syndr (2014) 0.92

Effect of hydration state on resistance exercise-induced endocrine markers of anabolism, catabolism, and metabolism. J Appl Physiol (1985) (2008) 0.92

Eight months of physical training in warm water improves physical and mental health in women with fibromyalgia: a randomized controlled trial. J Rehabil Med (2008) 0.92

Body composition and fitness during strength and/or endurance training in older men. Med Sci Sports Exerc (2008) 0.92