Carbohydrate restriction has a more favorable impact on the metabolic syndrome than a low fat diet.

PubWeight™: 1.57‹?› | Rank: Top 4%

🔗 View Article (PMID 19082851)

Published in Lipids on December 12, 2008

Authors

Jeff S Volek1, Stephen D Phinney, Cassandra E Forsythe, Erin E Quann, Richard J Wood, Michael J Puglisi, William J Kraemer, Doug M Bibus, Maria Luz Fernandez, Richard D Feinman

Author Affiliations

1: Department of Kinesiology, University of Connecticut, 2095 Hillside Road, Storrs, CT 06269-1110, USA. jeff.volek@uconn.edu

Associated clinical trials:

The Effects of Consuming Palm Oil With Different Macronutrient Intakes on Blood Lipids | NCT02922062

Dietary Intervention in Type-2 Diabetes and Pre-Diabetes | NCT02519309

Articles citing this

Calorie restriction increases fatty acid synthesis and whole body fat oxidation rates. Am J Physiol Endocrinol Metab (2009) 1.70

Efficacy and safety of a high protein, low carbohydrate diet for weight loss in severely obese adolescents. J Pediatr (2010) 1.57

Is there a role for carbohydrate restriction in the treatment and prevention of cancer? Nutr Metab (Lond) (2011) 1.35

Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets. Eur J Clin Nutr (2013) 1.25

Prevalence and Management of Dyslipidemia in Korea: Korea National Health and Nutrition Examination Survey during 1998 to 2010. Diabetes Metab J (2013) 1.12

Weight gain, metabolic syndrome, and breast cancer recurrence: are dietary recommendations supported by the data? Int J Breast Cancer (2012) 1.09

Low-fat versus low-carbohydrate weight reduction diets: effects on weight loss, insulin resistance, and cardiovascular risk: a randomized control trial. Diabetes (2009) 1.01

Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS). Dose Response (2014) 1.00

Effects of exogenous ketone supplementation on blood ketone, glucose, triglyceride, and lipoprotein levels in Sprague-Dawley rats. Nutr Metab (Lond) (2016) 0.96

Limited effect of dietary saturated fat on plasma saturated fat in the context of a low carbohydrate diet. Lipids (2010) 0.96

Fructose in perspective. Nutr Metab (Lond) (2013) 0.96

Low-carbohydrate diets and prostate cancer: how low is "low enough"? Cancer Prev Res (Phila) (2010) 0.94

The effects of a ketogenic diet on exercise metabolism and physical performance in off-road cyclists. Nutrients (2014) 0.94

Serum leptin concentrations are not related to dietary patterns but are related to sex, age, body mass index, serum triacylglycerol, serum insulin, and plasma glucose in the US population. Nutr Metab (Lond) (2009) 0.93

Tackling overweight and obesity: does the public health message match the science? BMC Med (2013) 0.92

Influence of a ketogenic diet, fish-oil, and calorie restriction on plasma metabolites and lipids in C57BL/6J mice. Nutr Metab (Lond) (2014) 0.90

Egg consumption modulates HDL lipid composition and increases the cholesterol-accepting capacity of serum in metabolic syndrome. Lipids (2013) 0.90

Is the metabolic syndrome caused by a high fructose, and relatively low fat, low cholesterol diet? Arch Med Sci (2011) 0.88

Effects of dairy on metabolic syndrome parameters: a review. Yale J Biol Med (2014) 0.88

Response of C57Bl/6 mice to a carbohydrate-free diet. Nutr Metab (Lond) (2012) 0.87

Acute effects of different diet compositions on skeletal muscle insulin signalling in obese individuals during caloric restriction. Metabolism (2012) 0.86

Acute metabolic responses to a high-carbohydrate meal in outpatients with type 2 diabetes treated with a low-carbohydrate diet: a crossover meal tolerance study. Nutr Metab (Lond) (2009) 0.85

Ketogenic diet for obesity: friend or foe? Int J Environ Res Public Health (2014) 0.84

Effects of dietary cold-pressed turnip rapeseed oil and butter on serum lipids, oxidized LDL and arterial elasticity in men with metabolic syndrome. Lipids Health Dis (2010) 0.83

Insulin sensitivity and glucose tolerance are altered by maintenance on a ketogenic diet. Endocrinology (2010) 0.82

Effects of consuming a high carbohydrate diet after eight weeks of exposure to a ketogenic diet. Nutr Metab (Lond) (2009) 0.82

Resistance training in overweight women on a ketogenic diet conserved lean body mass while reducing body fat. Nutr Metab (Lond) (2010) 0.82

Exercise and dietary-mediated reductions in postprandial lipemia. J Nutr Metab (2014) 0.80

High-intensity exercise and carbohydrate-reduced energy-restricted diet in obese individuals. Eur J Appl Physiol (2010) 0.80

Caloric Restriction as a Strategy to Improve Vascular Dysfunction in Metabolic Disorders. Nutrients (2016) 0.79

Advice to follow a low-carbohydrate diet has a favourable impact on low-grade inflammation in type 2 diabetes compared with advice to follow a low-fat diet. Ann Med (2014) 0.78

Reduction in urinary albumin excretion with a moderate low-carbohydrate diet in patients with type 2 diabetes: a 12-month intervention. Diabetes Metab Syndr Obes (2012) 0.78

Retinol Binding Protein 4 in Relation to Diet, Inflammation, Immunity, and Cardiovascular Diseases. Adv Nutr (2015) 0.77

Dietary magnesium intake and risk of metabolic syndrome: a meta-analysis. Diabet Med (2014) 0.77

The Effectiveness of Different Diet Strategies to Reduce Type 2 Diabetes Risk in Youth. Nutrients (2016) 0.77

Short term effects of a low-carbohydrate diet in overweight and obese subjects with low HDL-C levels. BMC Endocr Disord (2010) 0.76

Integrated Yoga and Naturopathy module in management of Metabolic Syndrome: A case report. J Ayurveda Integr Med (2017) 0.75

Impact of Nutrition on Cerebral Circulation and Cognition in the Metabolic Syndrome. Nutrients (2015) 0.75

An Online Intervention Comparing a Very Low-Carbohydrate Ketogenic Diet and Lifestyle Recommendations Versus a Plate Method Diet in Overweight Individuals With Type 2 Diabetes: A Randomized Controlled Trial. J Med Internet Res (2017) 0.75

The impact of weight gain during adjuvant chemotherapy on survival in breast cancer. Ulus Cerrahi Derg (2015) 0.75

Dietary Intake and Cardiovascular Risk Factors in Icelanders Following Voluntarily a Low Carbohydrate Diet. PLoS One (2016) 0.75

Man shall not live by bread alone. Nutrition (2014) 0.75

The Effects of Low-Carbohydrate Diets on Psychosocial Outcomes in Obesity/Overweight: A Systematic Review of Randomized, Controlled Studies. Nutrients (2016) 0.75

Dietary Intervention for Overweight and Obese Adults: Comparison of Low-Carbohydrate and Low-Fat Diets. A Meta-Analysis. PLoS One (2015) 0.75

Effects of an Ad Libitum Consumed Low-Fat Plant-Based Diet Supplemented with Plant-Based Meal Replacements on Body Composition Indices. Biomed Res Int (2017) 0.75

Dietary macronutrient distribution influences post-exercise substrate utilization in women: a cross-sectional evaluation of metabolic flexibility. J Sports Med Phys Fitness (2016) 0.75

Postprandial changes in cardiometabolic disease risk in young Chinese men following isocaloric high or low protein diets, stratified by either high or low meal frequency - a randomized controlled crossover trial. Nutr J (2016) 0.75

Muscle PGC-1α is required for long term systemic and local adaptations to a ketogenic diet in mice. Am J Physiol Endocrinol Metab (2017) 0.75

Articles by these authors

American College of Sports Medicine position stand. Progression models in resistance training for healthy adults. Med Sci Sports Exerc (2002) 4.33

Weight loss with self-help compared with a structured commercial program: a randomized trial. JAMA (2003) 3.36

Dietary factors associated with the risk of high iron stores in the elderly Framingham Heart Study cohort. Am J Clin Nutr (2002) 2.29

Muscular adaptations in response to three different resistance-training regimens: specificity of repetition maximum training zones. Eur J Appl Physiol (2002) 2.08

A prospective study of serum C-reactive protein and colorectal cancer risk in men. Cancer Res (2006) 2.02

Youth resistance training: updated position statement paper from the national strength and conditioning association. J Strength Cond Res (2009) 1.90

Relative bioavailability of calcium-rich dietary sources in the elderly. Am J Clin Nutr (2002) 1.59

Carbohydrate restriction improves the features of Metabolic Syndrome. Metabolic Syndrome may be defined by the response to carbohydrate restriction. Nutr Metab (Lond) (2005) 1.59

Foot strike patterns of runners at the 15-km point during an elite-level half marathon. J Strength Cond Res (2007) 1.51

Comparison of low fat and low carbohydrate diets on circulating fatty acid composition and markers of inflammation. Lipids (2007) 1.45

Dietary carbohydrate restriction in type 2 diabetes mellitus and metabolic syndrome: time for a critical appraisal. Nutr Metab (Lond) (2008) 1.44

Vitamin D status and the metabolic syndrome. Nutr Rev (2006) 1.42

Effects of exercise at different times on postprandial lipemia and endothelial function. Med Sci Sports Exerc (2008) 1.42

Low-carbohydrate nutrition and metabolism. Am J Clin Nutr (2007) 1.42

Body composition and hormonal responses to a carbohydrate-restricted diet. Metabolism (2002) 1.39

Cardioprotective effects of dietary polyphenols. J Nutr (2005) 1.39

Targeting insulin inhibition as a metabolic therapy in advanced cancer: a pilot safety and feasibility dietary trial in 10 patients. Nutrition (2012) 1.39

Impact of increased adipose tissue mass on inflammation, insulin resistance, and dyslipidemia. Curr Diab Rep (2009) 1.36

Grape polyphenols exert a cardioprotective effect in pre- and postmenopausal women by lowering plasma lipids and reducing oxidative stress. J Nutr (2005) 1.36

Acute and long-term effects of resistance exercise with or without protein ingestion on muscle hypertrophy and gene expression. Amino Acids (2008) 1.31

Dietary cholesterol from eggs increases plasma HDL cholesterol in overweight men consuming a carbohydrate-restricted diet. J Nutr (2008) 1.30

A ketogenic diet favorably affects serum biomarkers for cardiovascular disease in normal-weight men. J Nutr (2002) 1.30

Modulation of C-reactive protein, tumor necrosis factor-alpha, and adiponectin by diet, exercise, and weight loss. J Nutr (2008) 1.29

Dietary carbohydrate restriction induces a unique metabolic state positively affecting atherogenic dyslipidemia, fatty acid partitioning, and metabolic syndrome. Prog Lipid Res (2008) 1.28

Thermodynamics and metabolic advantage of weight loss diets. Metab Syndr Relat Disord (2003) 1.28

Waist circumference is a better predictor than body mass index of coronary heart disease risk in overweight premenopausal women. J Nutr (2004) 1.26

Modification of lipoproteins by very low-carbohydrate diets. J Nutr (2005) 1.26

Testosterone physiology in resistance exercise and training: the up-stream regulatory elements. Sports Med (2010) 1.25

Toll-like receptor 4 deficiency promotes the alternative activation of adipose tissue macrophages. Diabetes (2012) 1.25

Evaluation of a lower-body compression garment. J Sports Sci (2003) 1.23

Preconception hemoglobin and ferritin concentrations are associated with pregnancy outcome in a prospective cohort of Chinese women. J Nutr (2004) 1.23

Performance and physiologic adaptations to resistance training. Am J Phys Med Rehabil (2002) 1.22

Determining variables of plyometric training for improving vertical jump height performance: a meta-analysis. J Strength Cond Res (2009) 1.21

Relationship between the number of repetitions and selected percentages of one repetition maximum in free weight exercises in trained and untrained men. J Strength Cond Res (2006) 1.20

Resistance exercise biology: manipulation of resistance exercise programme variables determines the responses of cellular and molecular signalling pathways. Sports Med (2008) 1.19

National trends in beverage consumption in children from birth to 5 years: analysis of NHANES across three decades. Nutr J (2012) 1.18

Thermodynamics of weight loss diets. Nutr Metab (Lond) (2004) 1.17

Determination of functional strength imbalance of the lower extremities. J Strength Cond Res (2006) 1.16

Differential effects of strength training leading to failure versus not to failure on hormonal responses, strength, and muscle power gains. J Appl Physiol (1985) (2006) 1.16

Influence of exercise mode and osteogenic index on bone biomarker responses during short-term physical training. Bone (2009) 1.15

Position statement on youth resistance training: the 2014 International Consensus. Br J Sports Med (2013) 1.15

Very low-carbohydrate and low-fat diets affect fasting lipids and postprandial lipemia differently in overweight men. J Nutr (2004) 1.15

Muscle hypertrophy, hormonal adaptations and strength development during strength training in strength-trained and untrained men. Eur J Appl Physiol (2003) 1.15

Physical limits to spatial resolution of optical recording: clarifying the spatial structure of cortical hypercolumns. Proc Natl Acad Sci U S A (2005) 1.15

Changes in dynamic exercise performance following a sequence of preconditioning isometric muscle actions. J Strength Cond Res (2003) 1.15

Dietary phylloquinone depletion and repletion in older women. J Nutr (2003) 1.13

Hydration and muscular performance: does fluid balance affect strength, power and high-intensity endurance? Sports Med (2007) 1.11

Comparison of a very low-carbohydrate and low-fat diet on fasting lipids, LDL subclasses, insulin resistance, and postprandial lipemic responses in overweight women. J Am Coll Nutr (2004) 1.11

Comparison of methods for assessing body composition changes during weight loss. Med Sci Sports Exerc (2002) 1.08

Dietary cholesterol does not increase biomarkers for chronic disease in a pediatric population from northern Mexico. Am J Clin Nutr (2004) 1.08

Meeting and exceeding dairy recommendations: effects of dairy consumption on nutrient intakes and risk of chronic disease. Nutr Rev (2013) 1.07

An isoenergetic very low carbohydrate diet improves serum HDL cholesterol and triacylglycerol concentrations, the total cholesterol to HDL cholesterol ratio and postprandial pipemic responses compared with a low fat diet in normal weight, normolipidemic women. J Nutr (2003) 1.06

Mixed-methods resistance training increases power and strength of young and older men. Med Sci Sports Exerc (2002) 1.06

Histological and molecular analysis of the biceps tendon long head post-tenotomy. J Orthop Res (2009) 1.06

Carbohydrate restriction alters lipoprotein metabolism by modifying VLDL, LDL, and HDL subfraction distribution and size in overweight men. J Nutr (2006) 1.06

Effect of post-exercise supplement consumption on adaptations to resistance training. J Am Coll Nutr (2004) 1.05

Rapamycin, an mTOR inhibitor, disrupts triglyceride metabolism in guinea pigs. Metabolism (2006) 1.05

Neural factors account for strength decrements observed after short-term muscle unloading. Am J Physiol Regul Integr Comp Physiol (2002) 1.04

The effects of ten weeks of lower-body unstable surface training on markers of athletic performance. J Strength Cond Res (2007) 1.04

Reliability of performance measurements derived from ground reaction force data during countermovement jump and the influence of sampling frequency. J Strength Cond Res (2009) 1.04

The lowering of plasma lipids following a weight reduction program is related to increased expression of the LDL receptor and lipoprotein lipase. J Nutr (2005) 1.04

Once weekly combined resistance and cardiovascular training in healthy older men. Med Sci Sports Exerc (2004) 1.03

Maximal power at different percentages of one repetition maximum: influence of resistance and gender. J Strength Cond Res (2007) 1.02

Effects of strength training on muscle strength characteristics, functional capabilities, and balance in middle-aged and older women. J Strength Cond Res (2006) 1.02

Cytokine and hormone responses to resistance training. Eur J Appl Physiol (2009) 1.02

Iron and colorectal cancer risk in the alpha-tocopherol, beta-carotene cancer prevention study. Int J Cancer (2006) 1.02

Consortium for Health and Military Performance and American College of Sports Medicine consensus paper on extreme conditioning programs in military personnel. Curr Sports Med Rep (2011) 1.02

Grape polyphenols reduce blood pressure and increase flow-mediated vasodilation in men with metabolic syndrome. J Nutr (2012) 1.02

Grape polyphenols decrease plasma triglycerides and cholesterol accumulation in the aorta of ovariectomized guinea pigs. J Nutr (2003) 1.02

Carbohydrate-restricted versus low-glycemic-index diets for the treatment of insulin resistance and metabolic syndrome. Nutr Rev (2009) 1.02

Men classified as hypo- or hyperresponders to dietary cholesterol feeding exhibit differences in lipoprotein metabolism. J Nutr (2003) 1.02

Effect of hydration state on strength, power, and resistance exercise performance. Med Sci Sports Exerc (2007) 1.01

The ABCG5 polymorphism contributes to individual responses to dietary cholesterol and carotenoids in eggs. J Nutr (2006) 1.00

Consuming eggs for breakfast influences plasma glucose and ghrelin, while reducing energy intake during the next 24 hours in adult men. Nutr Res (2010) 1.00

Vitamin D-inducible calcium transport and gene expression in three Caco-2 cell lines. Am J Physiol Gastrointest Liver Physiol (2002) 0.99

Body composition, fitness, and metabolic health during strength and endurance training and their combination in middle-aged and older women. Eur J Appl Physiol (2009) 0.99

Rethinking fat as a fuel for endurance exercise. Eur J Sport Sci (2014) 0.99

Comparison between different off-season resistance training programs in Division III American college football players. J Strength Cond Res (2009) 0.99

SC-435, an ileal apical sodium co-dependent bile acid transporter (ASBT) inhibitor lowers plasma cholesterol and reduces atherosclerosis in guinea pigs. Atherosclerosis (2003) 0.99

Eggs distinctly modulate plasma carotenoid and lipoprotein subclasses in adult men following a carbohydrate-restricted diet. J Nutr Biochem (2009) 0.98

JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs. BMC Cardiovasc Disord (2005) 0.98

Pre-menopausal women, classified as hypo- or hyperresponders, do not alter their LDL/HDL ratio following a high dietary cholesterol challenge. J Am Coll Nutr (2002) 0.98

Whey protein supplementation during resistance training augments lean body mass. J Am Coll Nutr (2013) 0.98

Whole egg consumption improves lipoprotein profiles and insulin sensitivity to a greater extent than yolk-free egg substitute in individuals with metabolic syndrome. Metabolism (2012) 0.98

Effects of combined resistance and cardiovascular training on strength, power, muscle cross-sectional area, and endurance markers in middle-aged men. Eur J Appl Physiol (2004) 0.97

Carbohydrate restriction, as a first-line dietary intervention, effectively reduces biomarkers of metabolic syndrome in Emirati adults. J Nutr (2009) 0.97