Published in Traffic on June 01, 2003
Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments. J Cell Biol (2004) 1.52
Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I. J Immunol (2010) 1.20
Low frequency stimulation of mouse adrenal slices reveals a clathrin-independent, protein kinase C-mediated endocytic mechanism. J Physiol (2003) 1.12
From junior to senior: advice from the benefit of 20/20 hindsight. Mol Biol Cell (2014) 0.75
Use of the supported membrane tube assay system for real-time analysis of membrane fission reactions. Nat Protoc (2017) 0.75
Regulated portals of entry into the cell. Nature (2003) 15.33
Robust single-particle tracking in live-cell time-lapse sequences. Nat Methods (2008) 9.43
A dynamic actin cytoskeleton functions at multiple stages of clathrin-mediated endocytosis. Mol Biol Cell (2004) 3.80
Real-time visualization of dynamin-catalyzed membrane fission and vesicle release. Cell (2008) 3.75
Cargo and dynamin regulate clathrin-coated pit maturation. PLoS Biol (2009) 3.72
GTPase cycle of dynamin is coupled to membrane squeeze and release, leading to spontaneous fission. Cell (2008) 3.69
SNX9 couples actin assembly to phosphoinositide signals and is required for membrane remodeling during endocytosis. Dev Cell (2007) 2.73
The dynamin middle domain is critical for tetramerization and higher-order self-assembly. EMBO J (2006) 2.44
G domain dimerization controls dynamin's assembly-stimulated GTPase activity. Nature (2010) 2.31
Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis. J Cell Biol (2002) 2.18
Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals. J Cell Biol (2002) 2.17
SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis. Mol Biol Cell (2005) 2.08
The evolution of dynamin to regulate clathrin-mediated endocytosis: speculations on the evolutionarily late appearance of dynamin relative to clathrin-mediated endocytosis. Bioessays (2012) 2.07
Real-time detection reveals that effectors couple dynamin's GTP-dependent conformational changes to the membrane. EMBO J (2007) 2.00
Geometric catalysis of membrane fission driven by flexible dynamin rings. Science (2013) 1.95
Differential requirements for AP-2 in clathrin-mediated endocytosis. J Cell Biol (2003) 1.93
Conserved functions of membrane active GTPases in coated vesicle formation. Science (2009) 1.90
Isoform and splice-variant specific functions of dynamin-2 revealed by analysis of conditional knock-out cells. Mol Biol Cell (2008) 1.84
Cargo- and adaptor-specific mechanisms regulate clathrin-mediated endocytosis. J Cell Biol (2010) 1.83
Dissecting dynamin's role in clathrin-mediated endocytosis. Biochem Soc Trans (2009) 1.79
Discovery of antivirals against smallpox. Proc Natl Acad Sci U S A (2004) 1.76
Modulation of Rac localization and function by dynamin. Mol Biol Cell (2003) 1.75
A molecular motor or a regulator? Dynamin's in a class of its own. Biochemistry (2003) 1.69
Robust colorimetric assays for dynamin's basal and stimulated GTPase activities. Methods Enzymol (2005) 1.69
Advances in analysis of low signal-to-noise images link dynamin and AP2 to the functions of an endocytic checkpoint. Dev Cell (2013) 1.68
An intramolecular signaling element that modulates dynamin function in vitro and in vivo. Mol Biol Cell (2009) 1.68
An assembly-incompetent mutant establishes a requirement for dynamin self-assembly in clathrin-mediated endocytosis in vivo. Mol Biol Cell (2004) 1.67
The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways. J Cell Biol (2007) 1.66
Local clustering of transferrin receptors promotes clathrin-coated pit initiation. J Cell Biol (2010) 1.60
A pseudoatomic model of the dynamin polymer identifies a hydrolysis-dependent powerstroke. Cell (2011) 1.59
Endocytic accessory proteins are functionally distinguished by their differential effects on the maturation of clathrin-coated pits. Mol Biol Cell (2009) 1.58
An internal GAP domain negatively regulates presynaptic dynamin in vivo: a two-step model for dynamin function. J Cell Biol (2005) 1.57
Dynamin GTPase domain mutants that differentially affect GTP binding, GTP hydrolysis, and clathrin-mediated endocytosis. J Biol Chem (2004) 1.52
Membrane insertion of the pleckstrin homology domain variable loop 1 is critical for dynamin-catalyzed vesicle scission. Mol Biol Cell (2009) 1.42
Clusters of bioactive compounds target dynamic endomembrane networks in vivo. Proc Natl Acad Sci U S A (2011) 1.41
Phosphatidylinositol-(4,5)-bisphosphate regulates clathrin-coated pit initiation, stabilization, and size. Mol Biol Cell (2011) 1.41
SNX9 activities are regulated by multiple phosphoinositides through both PX and BAR domains. Traffic (2007) 1.40
A new role for the dynamin GTPase in the regulation of fusion pore expansion. Mol Biol Cell (2011) 1.28
Crystal structure of the GTPase domain of rat dynamin 1. Proc Natl Acad Sci U S A (2005) 1.28
Multivalent display and receptor-mediated endocytosis of transferrin on virus-like particles. Chembiochem (2010) 1.24
Hsc70 is required for endocytosis and clathrin function in Drosophila. J Cell Biol (2002) 1.21
Phosphatidic acid plays a regulatory role in clathrin-mediated endocytosis. Mol Biol Cell (2010) 1.15
Supported bilayers with excess membrane reservoir: a template for reconstituting membrane budding and fission. Biophys J (2010) 1.14
Hotspots organize clathrin-mediated endocytosis by efficient recruitment and retention of nucleating resources. Traffic (2011) 1.13
Differential curvature sensing and generating activities of dynamin isoforms provide opportunities for tissue-specific regulation. Proc Natl Acad Sci U S A (2011) 1.09
Context-dependent proangiogenic function of bone morphogenetic protein signaling is mediated by disabled homolog 2. Dev Cell (2012) 1.08
AAK1-mediated micro2 phosphorylation is stimulated by assembled clathrin. Traffic (2003) 1.07
Dual role of BAR domain-containing proteins in regulating vesicle release catalyzed by the GTPase, dynamin-2. J Biol Chem (2013) 1.06
Measuring the hierarchy of molecular events during clathrin-mediated endocytosis. Traffic (2011) 1.06
Common membrane trafficking defects of disease-associated dynamin 2 mutations. Traffic (2011) 1.02
CVAK104 is a novel poly-L-lysine-stimulated kinase that targets the beta2-subunit of AP2. J Biol Chem (2005) 1.00
Global and local regulation of clathrin-coated pit dynamics detected on patterned substrates. Biophys J (2009) 0.99
Discovery of substituted 4-(pyrazol-4-yl)-phenylbenzodioxane-2-carboxamides as potent and highly selective Rho kinase (ROCK-II) inhibitors. J Med Chem (2008) 0.97
Molecular Biology of the Cell: It's Our Journal. Mol Biol Cell (2005) 0.96
Clathrin-coated vesicle formation from isolated plasma membranes. Methods Enzymol (2005) 0.92
Signal recognition particle (SRP) and SRP receptor: a new paradigm for multistate regulatory GTPases. Biochemistry (2009) 0.91
Domain requirements for an endocytosis-independent, isoform-specific function of dynamin-2. Exp Cell Res (2006) 0.90
Analyzing membrane remodeling and fission using supported bilayers with excess membrane reservoir. Nat Protoc (2013) 0.87
Dynamin-catalyzed membrane fission requires coordinated GTP hydrolysis. PLoS One (2013) 0.85
Chroman-3-amides as potent Rho kinase inhibitors. Bioorg Med Chem Lett (2008) 0.85
Monitoring the autophagy pathway in cancer. Methods Enzymol (2009) 0.84
Tetrahydroisoquinoline derivatives as highly selective and potent Rho kinase inhibitors. J Med Chem (2010) 0.84
Cell biology: Lipid switches and traffic control. Nature (2013) 0.83
Structure-activity relationships, and drug metabolism and pharmacokinetic properties for indazole piperazine and indazole piperidine inhibitors of ROCK-II. Bioorg Med Chem Lett (2006) 0.82
The development of benzimidazoles as selective rho kinase inhibitors. Bioorg Med Chem Lett (2010) 0.81
Benzothiazoles as Rho-associated kinase (ROCK-II) inhibitors. Bioorg Med Chem Lett (2009) 0.80
A cell-free biochemical complementation assay reveals complex and redundant cytosolic requirements for LRP endocytosis. Exp Cell Res (2006) 0.80
Intrapolypeptide interactions between the GTPase effector domain (GED) and the GTPase domain form the bundle signaling element in dynamin dimers. Biochemistry (2014) 0.79
Synthesis and biological evaluation of 4-quinazolinones as Rho kinase inhibitors. Bioorg Med Chem Lett (2011) 0.78
Outcome and incidence of re-intervention after surgical repair of tetralogy of fallot. J Card Surg (2012) 0.78
Benzimidazole- and benzoxazole-based inhibitors of Rho kinase. Bioorg Med Chem Lett (2008) 0.78
Synthesis and biological evaluation of urea derivatives as highly potent and selective rho kinase inhibitors. J Med Chem (2013) 0.77
Amino acid derived quinazolines as Rock/PKA inhibitors. Bioorg Med Chem Lett (2013) 0.77
Integrated electron microscopy: super-duper resolution. PLoS Biol (2013) 0.75
Symetis Acurate aortic valve-in-valve implantation for early degeneration of a Sapien THV prosthesis. Ann Thorac Surg (2013) 0.75
Discovery and optimization of indoles and 7-azaindoles as Rho kinase (ROCK) inhibitors (part-I). Bioorg Med Chem Lett (2011) 0.75
[Medicine needs music! Music therapy for chronic pain]. Rev Med Suisse (2014) 0.75
Discovery and optimization of indole and 7-azaindoles as Rho kinase (ROCK) inhibitors (part-II). Bioorg Med Chem Lett (2011) 0.75