Published in Mol Pharmacol on June 01, 2003
Novel quinazolinone MJ-29 triggers endoplasmic reticulum stress and intrinsic apoptosis in murine leukemia WEHI-3 cells and inhibits leukemic mice. PLoS One (2012) 0.89
The therapeutic effect of a pulsed electromagnetic field on the reproductive patterns of male Wistar rats exposed to a 2.45-GHz microwave field. Clinics (Sao Paulo) (2011) 0.84
Acute toxicity of the antifouling compound butenolide in non-target organisms. PLoS One (2011) 0.82
Immunohistochemical evaluation of cell proliferation and apoptosis markers in ovarian surface epithelial cells of cladribine-treated rats. Protoplasma (2013) 0.79
Opposite effects of uracil and adenine nucleotides on the survival of murine cardiomyocytes. J Cell Mol Med (2008) 0.78
Suberoylanilide hydroxamic acid (SAHA) and cladribine synergistically induce apoptosis in NK-LGL leukaemia. Br J Haematol (2014) 0.78
Inhibition of DNA primase and induction of apoptosis by 3,3'-diethyl-9-methylthia-carbocyanine iodide in hepatocellular carcinoma BEL-7402 cells. World J Gastroenterol (2004) 0.77
Intrinsic apoptosis pathway in fallopian tube epithelial cells induced by cladribine. ScientificWorldJournal (2014) 0.75
Invited Lectures : Overviews Purinergic signalling: past, present and future. Purinergic Signal (2006) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Cannibalism of live lymphocytes by human metastatic but not primary melanoma cells. Cancer Res (2006) 2.77
Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis. J Clin Invest (2004) 2.59
The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor. EMBO J (2006) 2.17
Regulation of survivin function by Hsp90. Proc Natl Acad Sci U S A (2003) 1.86
Proton pump inhibitors induce apoptosis of human B-cell tumors through a caspase-independent mechanism involving reactive oxygen species. Cancer Res (2007) 1.83
Purinergic signalling: from normal behaviour to pathological brain function. Prog Neurobiol (2011) 1.76
Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli. EMBO Mol Med (2010) 1.72
Unravelling the complexity of T cell abnormalities in common variable immunodeficiency. J Immunol (2007) 1.70
Nucleotide-mediated calcium signaling in rat cortical astrocytes: Role of P2X and P2Y receptors. Glia (2003) 1.54
Endosomal compartment contributes to the propagation of CD95/Fas-mediated signals in type II cells. Biochem J (2008) 1.53
The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair. PLoS One (2008) 1.44
The effect of sex/gender on cardiovascular pharmacology. Curr Pharm Des (2011) 1.41
To be or not to be (inflamed)--is that the question in anti-inflammatory drug therapy of neurodegenerative disorders? Trends Pharmacol Sci (2005) 1.39
A critical interaction between NR2B and MAGUK in L-DOPA induced dyskinesia. J Neurosci (2006) 1.34
Purinergic signalling in inflammation of the central nervous system. Trends Neurosci (2009) 1.32
Cloning, pharmacological characterisation and distribution of the rat G-protein-coupled P2Y(13) receptor. Biochem Pharmacol (2004) 1.26
[alpha]-Secretase ADAM10 as well as [alpha]APPs is reduced in platelets and CSF of Alzheimer disease patients. Mol Med (2002) 1.26
Key concepts and critical issues on epoetin and filgrastim biosimilars. A position paper from the Italian Society of Hematology, Italian Society of Experimental Hematology, and Italian Group for Bone Marrow Transplantation. Haematologica (2011) 1.25
Pathophysiological roles of extracellular nucleotides in glial cells: differential expression of purinergic receptors in resting and activated microglia. Brain Res Brain Res Rev (2005) 1.24
Synapse-associated protein-97 mediates alpha-secretase ADAM10 trafficking and promotes its activity. J Neurosci (2007) 1.23
Are the available experimental models of type 2 diabetes appropriate for a gender perspective? Pharmacol Res (2007) 1.22
The microenvironment can shift erythrocytes from a friendly to a harmful behavior: pathogenetic implications for vascular diseases. Cardiovasc Res (2007) 1.20
Estrogen receptor profiles in human peripheral blood lymphocytes. Immunol Lett (2010) 1.19
Cardiolipin-enriched raft-like microdomains are essential activating platforms for apoptotic signals on mitochondria. FEBS Lett (2009) 1.19
Role of autophagy in immunity and autoimmunity, with a special focus on systemic lupus erythematosus. FASEB J (2012) 1.18
P66Shc signals to age. Aging (Albany NY) (2009) 1.18
Galectin-1 sensitizes resting human T lymphocytes to Fas (CD95)-mediated cell death via mitochondrial hyperpolarization, budding, and fission. J Biol Chem (2004) 1.17
Potent phagocytic activity discriminates metastatic and primary human malignant melanomas: a key role of ezrin. Lab Invest (2003) 1.17
CysLT1 leukotriene receptor antagonists inhibit the effects of nucleotides acting at P2Y receptors. Biochem Pharmacol (2005) 1.17
Decreased NR2B subunit synaptic levels cause impaired long-term potentiation but not long-term depression. J Neurosci (2009) 1.16
CysLT1 receptor is a target for extracellular nucleotide-induced heterologous desensitization: a possible feedback mechanism in inflammation. J Cell Sci (2005) 1.13
Calcium/calmodulin-dependent protein kinase II phosphorylation drives synapse-associated protein 97 into spines. J Biol Chem (2004) 1.13
Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines. J Pharmacol Exp Ther (2003) 1.12
Cellular and molecular mechanisms involved in hepatocellular carcinoma gender disparity. Int J Cancer (2010) 1.11
Critical requirement for cell cycle inhibitors in sustaining nonproliferative states. J Cell Biol (2007) 1.11
A role for P2X7 in microglial proliferation. J Neurochem (2006) 1.10
Transglutaminase overexpression sensitizes neuronal cell lines to apoptosis by increasing mitochondrial membrane potential and cellular oxidative stress. J Neurochem (2002) 1.09
The P2Y-like receptor GPR17 as a sensor of damage and a new potential target in spinal cord injury. Brain (2009) 1.07
CaMKII-dependent phosphorylation regulates SAP97/NR2A interaction. J Biol Chem (2003) 1.07
Potential role for IL-7 in Fas-mediated T cell apoptosis during HIV infection. J Immunol (2007) 1.07
Purinoceptor-mediated calcium signaling in primary neuron-glia trigeminal cultures. Cell Calcium (2007) 1.05
Phenotypic changes, signaling pathway, and functional correlates of GPR17-expressing neural precursor cells during oligodendrocyte differentiation. J Biol Chem (2011) 1.05
Tissue transglutaminase is a multifunctional BH3-only protein. J Biol Chem (2004) 1.04
Blockade of A2A adenosine receptors prevents basic fibroblast growth factor-induced reactive astrogliosis in rat striatal primary astrocytes. Glia (2003) 1.03
Autoantibodies to estrogen receptor α interfere with T lymphocyte homeostasis and are associated with disease activity in systemic lupus erythematosus. Arthritis Rheum (2012) 1.03
Cathepsin B inhibition interferes with metastatic potential of human melanoma: an in vitro and in vivo study. Mol Cancer (2010) 1.03
Development of an immobilized GPR17 receptor stationary phase for binding determination using frontal affinity chromatography coupled to mass spectrometry. Anal Biochem (2008) 1.02
Redox state, cell death and autoimmune diseases: a gender perspective. Autoimmun Rev (2008) 1.02
On the role of autophagy in human diseases: a gender perspective. J Cell Mol Med (2011) 1.02
Clostridium difficile toxin B causes apoptosis in epithelial cells by thrilling mitochondria. Involvement of ATP-sensitive mitochondrial potassium channels. J Biol Chem (2007) 1.02
Temporomandibular joint inflammation activates glial and immune cells in both the trigeminal ganglia and in the spinal trigeminal nucleus. Mol Pain (2010) 1.01
Cell sex: a new look at cell fate studies. FASEB J (2008) 1.01
Sex differences at cellular level: "cells have a sex". Handb Exp Pharmacol (2012) 1.01
Calcium-calmodulin-dependent protein kinase II phosphorylation modulates PSD-95 binding to NMDA receptors. Eur J Neurosci (2006) 1.01
Gene expression waves. Cell cycle independent collective dynamics in cultured cells. FEBS J (2007) 1.00
Acetylcholinesterase inhibitors increase ADAM10 activity by promoting its trafficking in neuroblastoma cell lines. J Neurochem (2004) 0.99
T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy. FASEB J (2012) 0.99
Synaptic localization and activity of ADAM10 regulate excitatory synapses through N-cadherin cleavage. J Neurosci (2010) 0.98
HIV-1 Nef triggers Vav-mediated signaling pathway leading to functional and morphological differentiation of dendritic cells. FASEB J (2003) 0.98
Distribution of interleukin-1 receptor complex at the synaptic membrane driven by interleukin-1β and NMDA stimulation. J Neuroinflammation (2011) 0.98
Cytotoxic necrotizing factor 1 prevents apoptosis via the Akt/IkappaB kinase pathway: role of nuclear factor-kappaB and Bcl-2. Mol Biol Cell (2007) 0.97
Genotype-dependent priming to self- and xeno-cannibalism in heterozygous and homozygous lymphoblasts from patients with Huntington's disease. J Neurochem (2006) 0.97
Functional characterization of two isoforms of the P2Y-like receptor GPR17: [35S]GTPgammaS binding and electrophysiological studies in 1321N1 cells. Am J Physiol Cell Physiol (2009) 0.97
The regulated expression, intracellular trafficking, and membrane recycling of the P2Y-like receptor GPR17 in Oli-neu oligodendroglial cells. J Biol Chem (2013) 0.97
The GPR17 receptor in NG2 expressing cells: focus on in vivo cell maturation and participation in acute trauma and chronic damage. Glia (2011) 0.96
Mitochondrial membrane hyperpolarization hijacks activated T lymphocytes toward the apoptotic-prone phenotype: homeostatic mechanisms of HIV protease inhibitors. J Immunol (2003) 0.96
Extrinsic purinergic regulation of neural stem/progenitor cells: implications for CNS development and repair. Stem Cell Rev (2012) 0.96
Fibroblast autophagy in fibrotic disorders. J Pathol (2012) 0.96
GPR17: molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors. BMC Bioinformatics (2008) 0.95
Peripheral benzodiazepine receptor ligands: mitochondrial transmembrane potential depolarization and apoptosis induction in rat C6 glioma cells. Biochem Pharmacol (2004) 0.95
DNA replication is intrinsically hindered in terminally differentiated myotubes. PLoS One (2010) 0.94
Functions, dysfunctions and possible therapeutic relevance of adenosine A2A receptors in Huntington's disease. Prog Neurobiol (2007) 0.94
Reducing the risk of overdiagnosis in lung cancer: a support from molecular biology. J Cell Physiol (2011) 0.94
Pyrimethamine induces apoptosis of melanoma cells via a caspase and cathepsin double-edged mechanism. Cancer Res (2008) 0.94
Changes of peripheral A2A adenosine receptors in chronic heart failure and cardiac transplantation. FASEB J (2002) 0.94
Extra virgin olive oil biophenols inhibit cell-mediated oxidation of LDL by increasing the mRNA transcription of glutathione-related enzymes. J Nutr (2004) 0.94
Lack of PSD-95 drives hippocampal neuronal cell death through activation of an alpha CaMKII transduction pathway. Eur J Neurosci (2002) 0.93
The recently deorphanized GPR80 (GPR99) proposed to be the P2Y15 receptor is not a genuine P2Y receptor. Trends Pharmacol Sci (2005) 0.93
Identification and relevance of the CD95-binding domain in the N-terminal region of ezrin. J Biol Chem (2003) 0.93
Regulation of A2B adenosine receptor functioning by tumour necrosis factor a in human astroglial cells. J Neurochem (2004) 0.93
Expression and contribution of satellite glial cells purinoceptors to pain transmission in sensory ganglia: an update. Neuron Glia Biol (2010) 0.93
Tyrosol, the major extra virgin olive oil compound, restored intracellular antioxidant defences in spite of its weak antioxidative effectiveness. Nutr Metab Cardiovasc Dis (2006) 0.92