PubRank

Jean-François Riou

Author PubWeight™ 42.33‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Targeting telomeres and telomerase. Biochimie 2007 2.02
2 Natural and pharmacological regulation of telomerase. Nucleic Acids Res 2002 1.92
3 A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres. J Am Chem Soc 2008 1.91
4 Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells. J Biol Chem 2006 1.74
5 Lamellipodium extension and cadherin adhesion: two cell responses to cadherin activation relying on distinct signalling pathways. J Cell Sci 2003 1.72
6 The G-quadruplex ligand telomestatin inhibits POT1 binding to telomeric sequences in vitro and induces GFP-POT1 dissociation from telomeres in human cells. Cancer Res 2006 1.62
7 Preferential binding of a G-quadruplex ligand to human chromosome ends. Nucleic Acids Res 2005 1.53
8 Stabilization of the c-myc gene promoter quadruplex by specific ligands' inhibitors of telomerase. Biochem Biophys Res Commun 2004 1.52
9 Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing. Nucleic Acids Res 2004 1.38
10 Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands. Oncogene 2005 1.36
11 Interaction of telomestatin with the telomeric single-strand overhang. J Biol Chem 2004 1.27
12 Preclinical antitumor activity of cabazitaxel, a semisynthetic taxane active in taxane-resistant tumors. Clin Cancer Res 2013 1.25
13 Activation of Gbetagamma signaling downstream of Wnt-11/Xfz7 regulates Cdc42 activity during Xenopus gastrulation. Dev Biol 2003 1.19
14 Topoisomerase IIIalpha is required for normal proliferation and telomere stability in alternative lengthening of telomeres. EMBO J 2008 1.15
15 A G-quadruplex structure within the 5'-UTR of TRF2 mRNA represses translation in human cells. Nucleic Acids Res 2010 1.13
16 Selective interaction of ethidium derivatives with quadruplexes: an equilibrium dialysis and electrospray ionization mass spectrometry analysis. Biochemistry 2003 1.07
17 Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells. Org Biomol Chem 2012 1.05
18 Human POT1 is required for efficient telomere C-rich strand replication in the absence of WRN. Genes Dev 2009 1.05
19 Sequence variant (CTAGGG)n in the human telomere favors a G-quadruplex structure containing a G.C.G.C tetrad. Nucleic Acids Res 2009 1.02
20 The G-quadruplex ligand telomestatin impairs binding of topoisomerase IIIalpha to G-quadruplex-forming oligonucleotides and uncaps telomeres in ALT cells. PLoS One 2009 1.00
21 Interactions of cryptolepine and neocryptolepine with unusual DNA structures. Biochimie 2003 0.99
22 Detection of telomerase inhibitors based on g-quadruplex ligands by a modified telomeric repeat amplification protocol assay. Cancer Res 2002 0.97
23 Resistance to the short term antiproliferative activity of the G-quadruplex ligand 12459 is associated with telomerase overexpression and telomere capping alteration. J Biol Chem 2003 0.90
24 Tetrasubstituted naphthalene diimide ligands with selectivity for telomeric G-quadruplexes and cancer cells. Bioorg Med Chem Lett 2010 0.88
25 A new steroid derivative stabilizes g-quadruplexes and induces telomere uncapping in human tumor cells. Mol Pharmacol 2007 0.87
26 Human telomeres that contain (CTAGGG)n repeats show replication dependent instability in somatic cells and the male germline. Nucleic Acids Res 2009 0.87
27 Affinity and selectivity of G4 ligands measured by FRET. Nucleic Acids Symp Ser (Oxf) 2005 0.86
28 DNA damage signaling induced by the G-quadruplex ligand 12459 is modulated by PPM1D/WIP1 phosphatase. Nucleic Acids Res 2013 0.85
29 Overexpression of Bcl-2 is associated with apoptotic resistance to the G-quadruplex ligand 12459 but is not sufficient to confer resistance to long-term senescence. Nucleic Acids Res 2005 0.83
30 Mix.1/2-dependent control of FGF availability during gastrulation is essential for pronephros development in Xenopus. Dev Biol 2008 0.81
31 Resistance to senescence induction and telomere shortening by a G-quadruplex ligand inhibitor of telomerase. Cancer Res 2003 0.81
32 2,6-Diphenylthiazolo[3,2-b][1,2,4]triazoles as telomeric G-quadruplex stabilizers. Bioorg Med Chem Lett 2009 0.81
33 Delineation of the domains required for physical and functional interaction of p14ARF with human topoisomerase I. Oncogene 2003 0.80
34 Targeting human telomerase for cancer therapeutics. Cytotechnology 2004 0.79
35 DNA and RNA quadruplex ligands. Nucleic Acids Symp Ser (Oxf) 2008 0.79
36 Cubilin, a high affinity receptor for fibroblast growth factor 8, is required for cell survival in the developing vertebrate head. J Biol Chem 2013 0.79
37 Proteome alteration induced by hTERT transfection of human fibroblast cells. Proteome Sci 2008 0.79
38 Effects of a halogenated G-quadruplex ligand from the pyridine dicarboxamide series on the terminal sequence of XpYp telomere in HT1080 cells. Biochimie 2012 0.78
39 The benzophenanthridine alkaloid fagaronine induces erythroleukemic cell differentiation by gene activation. Planta Med 2005 0.76
40 Telomerase: a dimeric ménage à trois. Chembiochem 2007 0.75
41 Synthesis and biological evaluation of new penta- and heptacyclic indolo- and quinolinocarbazole ring systems obtained via Pd(0) catalysed reductive N-heteroannulation. Org Biomol Chem 2010 0.75
42 Retinoic acid-dependent control of MAP kinase phosphatase-3 is necessary for early kidney development in Xenopus. Biol Cell 2012 0.75
43 Selective interactions of ethidiums with G-quadruplex DNA revealed by surface-enhanced Raman scattering. Anal Chem 2003 0.75
44 Differential expression of arid5b isoforms in Xenopus laevis pronephros. Int J Dev Biol 2014 0.75
45 Synthesis and biological evaluation of novel 4,5-bis(dialkylaminoalkyl)-substituted acridines as potent telomeric G-quadruplex ligands. Eur J Med Chem 2009 0.75