Published in Crit Care on May 08, 2003
Gender-related outcome difference is related to course of sepsis on mixed ICUs: a prospective, observational clinical study. Crit Care (2011) 1.10
4G/5G polymorphism of PAI-1 gene is associated with multiple organ dysfunction and septic shock in pneumonia induced severe sepsis: prospective, observational, genetic study. Crit Care (2010) 1.05
Lack of Toll-like receptor 4 and 2 polymorphisms in Korean patients with bacteremia. J Korean Med Sci (2006) 0.93
Epidemiology and recent trends of severe sepsis in Spain: a nationwide population-based analysis (2006-2011). BMC Infect Dis (2014) 0.90
Bench-to-bedside review: future novel diagnostics for sepsis - a systems biology approach. Crit Care (2013) 0.86
PPARα mediates the anti-inflammatory effect of simvastatin in an experimental model of zymosan-induced multiple organ failure. Br J Pharmacol (2011) 0.85
Predisposition, insult/infection, response and organ dysfunction (PIRO): a pilot clinical staging system for hospital mortality in patients with infection. PLoS One (2013) 0.82
Hospital acquired blood stream infection as an adverse outcome for patients admitted to hospital with other principle diagnosis. Saudi J Anaesth (2014) 0.79
Clinical associations of host genetic variations in the genes of cytokines in critically ill patients. Clin Exp Immunol (2015) 0.79
Multiple gene-to-gene interactions in children with sepsis: a combination of five gene variants predicts outcome of life-threatening sepsis. Crit Care (2014) 0.79
Genetic susceptibility to nosocomial pneumonia, acute respiratory distress syndrome and poor outcome in patients at risk of critical illness. Inflammation (2014) 0.76
Genetic dissection of host immune response in pneumonia development and progression. Sci Rep (2016) 0.75
Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med (2013) 39.56
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med (2008) 31.57
2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med (2003) 28.68
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. Crit Care Med (2004) 24.47
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med (2013) 17.37
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med (2007) 13.90
Sepsis in European intensive care units: results of the SOAP study. Crit Care Med (2006) 11.78
2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Intensive Care Med (2003) 10.39
High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure. N Engl J Med (2015) 10.15
Mortality after surgery in Europe: a 7 day cohort study. Lancet (2012) 9.96
Comparison of dopamine and norepinephrine in the treatment of shock. N Engl J Med (2010) 8.58
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med (2007) 8.33
High versus low blood-pressure target in patients with septic shock. N Engl J Med (2014) 7.37
Intravascular Complications of Central Venous Catheterization by Insertion Site. N Engl J Med (2015) 7.02
The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Crit Care Med (2010) 6.69
Toll-like receptor 4 polymorphisms and atherogenesis. N Engl J Med (2002) 6.00
Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock. Crit Care Med (2004) 5.90
Microvascular blood flow is altered in patients with sepsis. Am J Respir Crit Care Med (2002) 5.84
Transfusion requirements after cardiac surgery: the TRACS randomized controlled trial. JAMA (2010) 5.80
Transfusion requirements in surgical oncology patients: a prospective, randomized controlled trial. Anesthesiology (2015) 5.52
Circulatory shock. N Engl J Med (2013) 4.95
Sepsis biomarkers: a review. Crit Care (2010) 4.76
The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Intensive Care Med (2010) 4.64
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. Intensive Care Med (2004) 4.56
Inhaled nitric oxide does not reduce mortality in patients with acute respiratory distress syndrome regardless of severity: systematic review and meta-analysis. Crit Care Med (2014) 4.11
Outcomes of the Surviving Sepsis Campaign in intensive care units in the USA and Europe: a prospective cohort study. Lancet Infect Dis (2012) 4.07
Cost-effectiveness of drotrecogin alfa (activated) in the treatment of severe sepsis. Crit Care Med (2003) 4.04
Early changes in organ function predict eventual survival in severe sepsis. Crit Care Med (2005) 3.97
Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury. Crit Care (2013) 3.90
Pulse pressure variations to predict fluid responsiveness: influence of tidal volume. Intensive Care Med (2005) 3.81
Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trial. JAMA (2013) 3.78
Management of bleeding and coagulopathy following major trauma: an updated European guideline. Crit Care (2013) 3.65
High tidal volume and positive fluid balance are associated with worse outcome in acute lung injury. Chest (2005) 3.58
The effects of dobutamine on microcirculatory alterations in patients with septic shock are independent of its systemic effects. Crit Care Med (2006) 3.53
The effect of selenium therapy on mortality in patients with sepsis syndrome: a systematic review and meta-analysis of randomized controlled trials. Crit Care Med (2013) 3.43
Candida bloodstream infections in intensive care units: analysis of the extended prevalence of infection in intensive care unit study. Crit Care Med (2011) 3.34
The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material. Intensive Care Med (2012) 3.18
Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis. Crit Care Med (2003) 3.18
The next generation of sepsis clinical trial designs: what is next after the demise of recombinant human activated protein C?*. Crit Care Med (2014) 3.17
Severe community-acquired pneumonia as a cause of severe sepsis: data from the PROWESS study. Crit Care Med (2005) 3.14
Management of bleeding following major trauma: an updated European guideline. Crit Care (2010) 3.09
Epidemiology, management, and risk factors for death of invasive Candida infections in critical care: a multicenter, prospective, observational study in France (2005-2006). Crit Care Med (2009) 3.07
Microvascular response to red blood cell transfusion in patients with severe sepsis. Crit Care Med (2007) 3.06
Epidemiology of sepsis in Germany: results from a national prospective multicenter study. Intensive Care Med (2007) 2.97
The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy. Immunol Rev (2007) 2.96
C-reactive protein levels correlate with mortality and organ failure in critically ill patients. Chest (2003) 2.95
Validation of cell-cycle arrest biomarkers for acute kidney injury using clinical adjudication. Am J Respir Crit Care Med (2014) 2.93
Immediate percutaneous coronary intervention is associated with better survival after out-of-hospital cardiac arrest: insights from the PROCAT (Parisian Region Out of hospital Cardiac ArresT) registry. Circ Cardiovasc Interv (2010) 2.91
Mortality rates for patients with acute lung injury/ARDS have decreased over time. Chest (2008) 2.90
Let us use the pulmonary artery catheter correctly and only when we need it. Crit Care Med (2005) 2.83
Results of the CONTROL trial: efficacy and safety of recombinant activated Factor VII in the management of refractory traumatic hemorrhage. J Trauma (2010) 2.82
Role of prednisolone treatment in severe Mycoplasma pneumoniae pneumonia in children. Pediatr Pulmonol (2006) 2.74
Albumin administration improves organ function in critically ill hypoalbuminemic patients: A prospective, randomized, controlled, pilot study. Crit Care Med (2006) 2.74
Do all nonsurvivors of cardiogenic shock die with a low cardiac index? Chest (2003) 2.73
Has mortality from acute renal failure decreased? A systematic review of the literature. Am J Med (2005) 2.73
Microcirculatory alterations in patients with severe sepsis: impact of time of assessment and relationship with outcome. Crit Care Med (2013) 2.72
Short- and long-term outcome in elderly patients after out-of-hospital cardiac arrest: a cohort study. Crit Care Med (2014) 2.70
Evaluation of sublingual and gut mucosal microcirculation in sepsis: a quantitative analysis. Crit Care Med (2009) 2.68
Abandon the mouse research ship? Not just yet! Shock (2014) 2.60
PIRO score for community-acquired pneumonia: a new prediction rule for assessment of severity in intensive care unit patients with community-acquired pneumonia. Crit Care Med (2009) 2.59
Influence of overweight on ICU mortality: a prospective study. Chest (2004) 2.54
Immunologic and hemodynamic effects of "low-dose" hydrocortisone in septic shock: a double-blind, randomized, placebo-controlled, crossover study. Am J Respir Crit Care Med (2002) 2.52
Efficacy and safety of first-line rituximab in severe, acquired thrombotic thrombocytopenic purpura with a suboptimal response to plasma exchange. Experience of the French Thrombotic Microangiopathies Reference Center. Crit Care Med (2012) 2.51
Sources of variability on the estimate of treatment effect in the PROWESS trial: implications for the design and conduct of future studies in severe sepsis. Crit Care Med (2004) 2.48
Does dopamine administration in shock influence outcome? Results of the Sepsis Occurrence in Acutely Ill Patients (SOAP) Study. Crit Care Med (2006) 2.47
Practice and perception--a nationwide survey of therapy habits in sepsis. Crit Care Med (2008) 2.43
Sublingual capnometry tracks microcirculatory changes in septic patients. Intensive Care Med (2006) 2.40
Ethics and end-of-life care for adults in the intensive care unit. Lancet (2010) 2.40
Management of bleeding following major trauma: a European guideline. Crit Care (2007) 2.40
Antibiotic strategies in severe nosocomial sepsis: why do we not de-escalate more often? Crit Care Med (2012) 2.39
Efficacy and safety of intravenous infusion of doripenem versus imipenem in ventilator-associated pneumonia: a multicenter, randomized study. Crit Care Med (2008) 2.37
HLA and infectious diseases. Clin Microbiol Rev (2009) 2.35
Practice parameters for hemodynamic support of sepsis in adult patients: 2004 update. Crit Care Med (2004) 2.33
Severe sepsis in cirrhosis. Hepatology (2009) 2.33
A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis. Crit Care Med (2010) 2.31
Obesity is associated with increased morbidity but not mortality in critically ill patients. Intensive Care Med (2008) 2.27
The prognostic value of muscle StO2 in septic patients. Intensive Care Med (2007) 2.25
Effects of dopamine, norepinephrine, and epinephrine on the splanchnic circulation in septic shock: which is best? Crit Care Med (2003) 2.23
Gamma-globulin levels in patients with community-acquired septic shock. Shock (2009) 2.21
Diagnostic and prognostic implications of endotoxemia in critical illness: results of the MEDIC study. J Infect Dis (2004) 2.17
A large-bolus injection, but not continuous infusion of sodium selenite improves outcome in peritonitis. Shock (2009) 2.17
Parthenolide and its photochemically synthesized 1(10)Z isomer: chemical reactivity and structure-activity relationship studies in human leucocyte chemotaxis. Bioorg Med Chem (2003) 2.16
Benefit of an early and systematic imaging procedure after cardiac arrest: insights from the PROCAT (Parisian Region Out of Hospital Cardiac Arrest) registry. Resuscitation (2012) 2.13
Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock. Crit Care (2010) 2.11
Diabetes does not alter mortality or hemostatic and inflammatory responses in patients with severe sepsis. Crit Care Med (2010) 2.11
Association between duration of storage of transfused red blood cells and morbidity and mortality in adult patients: myth or reality? Transfusion (2009) 2.11
Randomized, controlled clinical trials in sepsis: has methodological quality improved over time? Crit Care Med (2002) 2.10
Prevalence and factors of intensive care unit conflicts: the conflicus study. Am J Respir Crit Care Med (2009) 2.08
The Surviving Sepsis Campaign: raising awareness to reduce mortality. Crit Care (2003) 2.07
Dopamine versus norepinephrine in the treatment of septic shock: a meta-analysis*. Crit Care Med (2012) 2.06
Effects of fluids on microvascular perfusion in patients with severe sepsis. Intensive Care Med (2010) 2.05
Brain natriuretic peptide: A marker of myocardial dysfunction and prognosis during severe sepsis. Crit Care Med (2004) 2.05