Published in RNA on July 01, 2003
Prp8 protein: at the heart of the spliceosome. RNA (2005) 2.89
Exon junction complexes mediate the enhancing effect of splicing on mRNA expression. Proc Natl Acad Sci U S A (2003) 2.52
A molecular link between SR protein dephosphorylation and mRNA export. Proc Natl Acad Sci U S A (2004) 2.49
Cotranscriptional recruitment of the mRNA export factor Yra1 by direct interaction with the 3' end processing factor Pcf11. Mol Cell (2008) 2.16
The Ref/Aly proteins are dispensable for mRNA export and development in Caenorhabditis elegans. RNA (2003) 1.58
Crystal structure of the human ATP-dependent splicing and export factor UAP56. Proc Natl Acad Sci U S A (2004) 1.54
UAP56 couples piRNA clusters to the perinuclear transposon silencing machinery. Cell (2012) 1.53
The UL69 transactivator protein of human cytomegalovirus interacts with DEXD/H-Box RNA helicase UAP56 to promote cytoplasmic accumulation of unspliced RNA. Mol Cell Biol (2006) 1.50
UIF, a New mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA. Curr Biol (2009) 1.45
Ubiquitin-mediated mRNP dynamics and surveillance prior to budding yeast mRNA export. Genes Dev (2010) 1.43
Amino acid residue doublet propensity in the protein-RNA interface and its application to RNA interface prediction. Nucleic Acids Res (2006) 1.41
Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication. PLoS Pathog (2008) 1.37
In vivo recruitment of exon junction complex proteins to transcription sites in mammalian cell nuclei. RNA (2004) 1.35
ATP-dependent recruitment of export factor Aly/REF onto intronless mRNAs by RNA helicase UAP56. Mol Cell Biol (2007) 1.30
Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF(65). PLoS One (2007) 1.28
Efficient nuclear export of herpes simplex virus 1 transcripts requires both RNA binding by ICP27 and ICP27 interaction with TAP/NXF1. J Virol (2008) 1.19
Homolog of BRCA2-interacting Dss1p and Uap56p link Mlo3p and Rae1p for mRNA export in fission yeast. EMBO J (2005) 1.15
The solution structure of REF2-I reveals interdomain interactions and regions involved in binding mRNA export factors and RNA. RNA (2006) 1.14
SRp54 (SFRS11), a regulator for tau exon 10 alternative splicing identified by an expression cloning strategy. Mol Cell Biol (2006) 1.13
Kaposi's sarcoma-associated herpesvirus ORF57 in viral RNA processing. Front Biosci (Landmark Ed) (2009) 1.13
The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression. Mol Biol Cell (2010) 1.10
Retropseudogenes derived from the human Ro/SS-A autoantigen-associated hY RNAs. Nucleic Acids Res (2005) 1.03
Kaposi's sarcoma-associated herpesvirus ORF57 interacts with cellular RNA export cofactors RBM15 and OTT3 to promote expression of viral ORF59. J Virol (2010) 1.03
The two steps of poly(A)-dependent termination, pausing and release, can be uncoupled by truncation of the RNA polymerase II carboxyl-terminal repeat domain. Mol Cell Biol (2004) 1.02
Transcription Factor Activity Mapping of a Tissue-Specific in vivo Gene Regulatory Network. Cell Syst (2015) 0.92
The Drosophila U1-70K protein is required for viability, but its arginine-rich domain is dispensable. Genetics (2004) 0.90
Arabidopsis DEAD-box RNA helicase UAP56 interacts with both RNA and DNA as well as with mRNA export factors. PLoS One (2013) 0.84
A specific set of exon junction complex subunits is required for the nuclear retention of unspliced RNAs in Caenorhabditis elegans. Mol Cell Biol (2012) 0.82
Nuclear imprisonment: viral strategies to arrest host mRNA nuclear export. Viruses (2013) 0.82
An essential nuclear protein in trypanosomes is a component of mRNA transcription/export pathway. PLoS One (2011) 0.82
RSR-2, the Caenorhabditis elegans ortholog of human spliceosomal component SRm300/SRRM2, regulates development by influencing the transcriptional machinery. PLoS Genet (2013) 0.81
The cellular DExD/H-box RNA-helicases UAP56 and URH49 exhibit a CRM1-independent nucleocytoplasmic shuttling activity. PLoS One (2011) 0.80
Regulation of bovine papillomavirus type 1 gene expression by RNA processing. Front Biosci (Landmark Ed) (2009) 0.80
Highly pathogenic avian influenza virus nucleoprotein interacts with TREX complex adaptor protein Aly/REF. PLoS One (2013) 0.78
Transcriptional signatures of somatic neoblasts and germline cells in Macrostomum lignano. Elife (2016) 0.75
A genomic glance at the components of the mRNA export machinery in Plasmodium falciparum. Commun Integr Biol (2010) 0.75
UAP56 is a conserved crucial component of a divergent mRNA export pathway in Toxoplasma gondii. Mol Microbiol (2016) 0.75
Cell Biology of the Caenorhabditis elegans Nucleus. Genetics (2017) 0.75
The genetics of Caenorhabditis elegans. Genetics (1974) 102.14
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature (1998) 72.56
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature (2003) 26.58
Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences. EMBO J (1991) 23.69
The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions. EMBO J (2000) 7.54
TREX is a conserved complex coupling transcription with messenger RNA export. Nature (2002) 6.53
The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay. EMBO J (2001) 5.69
The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans. Nature (2000) 5.57
Some cis- and trans-acting mutants for splicing target pre-mRNA to the cytoplasm. Cell (1989) 5.46
The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human. EMBO J (1999) 4.49
Analysis of the constancy of DNA sequences during development and evolution of the nematode Caenorhabditis elegans. Proc Natl Acad Sci U S A (1979) 4.26
REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export. RNA (2000) 4.10
Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. Trends Biochem Sci (1999) 3.97
Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly. Nature (2001) 3.94
Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm. Mol Cell (2000) 3.86
SR splicing factors serve as adapter proteins for TAP-dependent mRNA export. Mol Cell (2003) 3.61
Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p. Nature (2001) 3.35
Role of polyadenylation in nucleocytoplasmic transport of mRNA. Mol Cell Biol (1996) 3.26
Stable mRNP formation and export require cotranscriptional recruitment of the mRNA export factors Yra1p and Sub2p by Hpr1p. Mol Cell Biol (2002) 3.18
Splicing factors SRp20 and 9G8 promote the nucleocytoplasmic export of mRNA. Mol Cell (2001) 3.14
RNA recognition by the human polyadenylation factor CstF. Mol Cell Biol (1997) 2.84
A quantitative analysis of intron effects on mammalian gene expression. RNA (2003) 2.80
The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in Drosophila. Curr Biol (2001) 2.70
U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction. Genes Dev (1997) 2.67
Both subunits of U2AF recognize the 3' splice site in Caenorhabditis elegans. Nature (1999) 2.65
Complex protein interactions within the human polyadenylation machinery identify a novel component. Mol Cell Biol (2000) 2.55
REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export. J Cell Biol (2002) 2.55
Analysis of the stimulatory effect of splicing on mRNA production and utilization in mammalian cells. RNA (2003) 2.40
Translation is required to remove Y14 from mRNAs in the cytoplasm. Curr Biol (2002) 2.28
Immunofluorescence visualization of germ-line-specific cytoplasmic granules in embryos, larvae, and adults of Caenorhabditis elegans. Proc Natl Acad Sci U S A (1982) 2.25
Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for sub2, an essential spliceosomal ATPase. Genes Dev (2001) 2.24
Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex. EMBO J (2001) 2.13
Allele-specific genetic interactions between Prp8 and RNA active site residues suggest a function for Prp8 at the catalytic core of the spliceosome. Genes Dev (1999) 2.12
TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture. Mol Cell Biol (2000) 2.07
Functional characterization of SR and SR-related genes in Caenorhabditis elegans. EMBO J (2000) 2.05
The DECD box putative ATPase Sub2p is an early mRNA export factor. Curr Biol (2001) 1.98
5' exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly. Genes Dev (2002) 1.98
The protein Mago provides a link between splicing and mRNA localization. EMBO Rep (2001) 1.92
Multiple roles for the yeast SUB2/yUAP56 gene in splicing. Genes Dev (2001) 1.91
Functional properties of p54, a novel SR protein active in constitutive and alternative splicing. Mol Cell Biol (1996) 1.90
Overexpression of TAP/p15 heterodimers bypasses nuclear retention and stimulates nuclear mRNA export. J Biol Chem (2001) 1.84
Translational control of maternal glp-1 mRNA establishes an asymmetry in the C. elegans embryo. Cell (1994) 1.77
Similarity of DNA binding and transcriptional regulation by Caenorhabditis elegans MAB-3 and Drosophila melanogaster DSX suggests conservation of sex determining mechanisms. Development (1999) 1.60
Identification and characterization of yUAP/Sub2p, a yeast homolog of the essential human pre-mRNA splicing factor hUAP56. Genes Dev (2001) 1.60
PUF60: a novel U2AF65-related splicing activity. RNA (1999) 1.59
The Ref/Aly proteins are dispensable for mRNA export and development in Caenorhabditis elegans. RNA (2003) 1.58
The prespliceosome components SAP 49 and SAP 145 interact in a complex implicated in tethering U2 snRNP to the branch site. Genes Dev (1994) 1.57
The mRNA export in Caenorhabditis elegans is mediated by Ce-NXF-1, an ortholog of human TAP/NXF and Saccharomyces cerevisiae Mex67p. RNA (2000) 1.52
A general approach for identification of RNA-protein cross-linking sites within native human spliceosomal small nuclear ribonucleoproteins (snRNPs). Analysis of RNA-protein contacts in native U1 and U4/U6.U5 snRNPs. J Biol Chem (2000) 1.45
HEL/UAP56 binds cotranscriptionally to the Balbiani ring pre-mRNA in an intron-independent manner and accompanies the BR mRNP to the nuclear pore. Curr Biol (2002) 1.25
Cloning of Caenorhabditis U2AF65: an alternatively spliced RNA containing a novel exon. Mol Cell Biol (1997) 1.21
Connections between the processing and nuclear export of mRNA: evidence for an export license? Proc Natl Acad Sci U S A (2000) 1.16
A role for SRp54 during intron bridging of small introns with pyrimidine tracts upstream of the branch point. Mol Cell Biol (1998) 1.13
IDA-1, a Caenorhabditis elegans homolog of the diabetic autoantigens IA-2 and phogrin, is expressed in peptidergic neurons in the worm. J Comp Neurol (2001) 1.07
mRNA export: travelling with DEAD box proteins. Curr Biol (2001) 1.06
mag-1, a homolog of Drosophila mago nashi, regulates hermaphrodite germ-line sex determination in Caenorhabditis elegans. Dev Biol (2000) 1.04
Both loss-of-function and gain-of-function mutations in snf define a role for snRNP proteins in regulating Sex-lethal pre-mRNA splicing in Drosophila development. Genetics (1996) 1.04
An exon that prevents transport of a mature mRNA. Proc Natl Acad Sci U S A (1999) 1.03
A suboptimal 5' splice site is a cis-acting determinant of nuclear export of polyomavirus late mRNAs. Mol Cell Biol (1996) 1.00
The BAT1 gene in the MHC encodes an evolutionarily conserved putative nuclear RNA helicase of the DEAD family. Genomics (1995) 0.99
Run-around PCR: a novel way to create duplications using polymerase chain reaction. Biotechniques (1995) 0.99
The Drosophila U2 snRNP protein U2A' has an essential function that is SNF/U2B" independent. Nucleic Acids Res (2001) 0.89
The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics. PLoS Biol (2003) 13.32
Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily. Expert Opin Drug Metab Toxicol (2008) 3.37
Coexpression of neighboring genes in Caenorhabditis elegans is mostly due to operons and duplicate genes. Genome Res (2003) 3.10
A global analysis of C. elegans trans-splicing. Genome Res (2010) 1.69
Crystal structure of UAP56, a DExD/H-box protein involved in pre-mRNA splicing and mRNA export. Structure (2004) 1.33
U2AF binding selects for the high conservation of the C. elegans 3' splice site. RNA (2005) 1.30
Aldehyde dehydrogenases in cellular responses to oxidative/electrophilic stress. Free Radic Biol Med (2012) 1.26
Update on the aldehyde dehydrogenase gene (ALDH) superfamily. Hum Genomics (2011) 1.26
Aldehyde dehydrogenase 1B1: molecular cloning and characterization of a novel mitochondrial acetaldehyde-metabolizing enzyme. Drug Metab Dispos (2010) 1.24
C. elegans sequences that control trans-splicing and operon pre-mRNA processing. RNA (2007) 1.18
Genome-wide identification and analysis of grape aldehyde dehydrogenase (ALDH) gene superfamily. PLoS One (2012) 1.09
A novel family of C. elegans snRNPs contains proteins associated with trans-splicing. RNA (2007) 1.09
The genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy due to mutations in ALDH7A1. J Inherit Metab Dis (2010) 1.08
Trans-splicing. Wiley Interdiscip Rev RNA (2011) 1.06
Aldehyde dehydrogenase 3B1 (ALDH3B1): immunohistochemical tissue distribution and cellular-specific localization in normal and cancerous human tissues. J Histochem Cytochem (2010) 1.01
Polycistronic pre-mRNA processing in vitro: snRNP and pre-mRNA role reversal in trans-splicing. Genes Dev (2010) 1.00
An uncapped RNA suggests a model for Caenorhabditis elegans polycistronic pre-mRNA processing. RNA (2003) 0.96
Gemfibrozil disrupts lysophosphatidylcholine and bile acid homeostasis via PPARα and its relevance to hepatotoxicity. Arch Toxicol (2014) 0.95
Molecular characterization, expression analysis, and role of ALDH3B1 in the cellular protection against oxidative stress. Free Radic Biol Med (2010) 0.87
The transcription start site landscape of C. elegans. Genome Res (2013) 0.86
Functional redundancy of worm spliceosomal proteins U1A and U2B''. Proc Natl Acad Sci U S A (2007) 0.86
Medicine. The cart before the horse. Science (2008) 0.85
Identification of transcription start sites of trans-spliced genes: uncovering unusual operon arrangements. RNA (2010) 0.84
RNA polymerase II C-terminal domain phosphorylation patterns in Caenorhabditis elegans operons, polycistronic gene clusters with only one promoter. Mol Cell Biol (2010) 0.84
Aldehyde dehydrogenases are regulators of hematopoietic stem cell numbers and B-cell development. Exp Hematol (2011) 0.82
RNA processing in C. elegans. Methods Cell Biol (2011) 0.81
Exploring nematode diversity. Nat Genet (2004) 0.79
Hepatic sirtuin 1 is dispensable for fibrate-induced peroxisome proliferator-activated receptor-α function in vivo. Am J Physiol Endocrinol Metab (2014) 0.78
SL trans-splicing in a Caenorhabditis elegans in vitro extract. Cold Spring Harb Protoc (2011) 0.75