Published in Acta Crystallogr D Biol Crystallogr on June 27, 2003
PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr D Biol Crystallogr (2010) 108.52
Overview of the CCP4 suite and current developments. Acta Crystallogr D Biol Crystallogr (2011) 67.55
Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7. Nat Protoc (2008) 16.53
BALBES: a molecular-replacement pipeline. Acta Crystallogr D Biol Crystallogr (2007) 9.29
Transfer of carbohydrate-active enzymes from marine bacteria to Japanese gut microbiota. Nature (2010) 5.08
Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis. Cell (2006) 4.49
Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor. Immunity (2012) 2.58
Data to knowledge: how to get meaning from your result. IUCrJ (2015) 2.23
Metal ion roles and the movement of hydrogen during reaction catalyzed by D-xylose isomerase: a joint x-ray and neutron diffraction study. Structure (2010) 2.20
Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site. EMBO J (2004) 2.14
Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis. Cell (2011) 2.11
JLigand: a graphical tool for the CCP4 template-restraint library. Acta Crystallogr D Biol Crystallogr (2012) 2.08
NMDA receptor structures reveal subunit arrangement and pore architecture. Nature (2014) 1.99
Molecular basis for shared cytokine recognition revealed in the structure of an unusually high affinity complex between IL-13 and IL-13Ralpha2. Structure (2010) 1.79
Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA. Nat Struct Mol Biol (2010) 1.72
Effectiveness of nonpeptide clinical inhibitor TMC-114 on HIV-1 protease with highly drug resistant mutations D30N, I50V, and L90M. J Med Chem (2006) 1.69
Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114. J Mol Biol (2006) 1.66
Detection and analysis of unusual features in the structural model and structure-factor data of a birch pollen allergen. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 1.64
Structural basis of recognition of interferon-α receptor by tyrosine kinase 2. Nat Struct Mol Biol (2014) 1.64
Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase. Proc Natl Acad Sci U S A (2009) 1.63
Crystal structures of fibronectin-binding sites from Staphylococcus aureus FnBPA in complex with fibronectin domains. Proc Natl Acad Sci U S A (2008) 1.62
Botulinum neurotoxin is shielded by NTNHA in an interlocked complex. Science (2012) 1.62
Rational design of inhibitors and activity-based probes targeting Clostridium difficile virulence factor TcdB. Chem Biol (2010) 1.60
Open structure of the Ca2+ gating ring in the high-conductance Ca2+-activated K+ channel. Nature (2011) 1.60
Structural and functional basis of CXCL12 (stromal cell-derived factor-1 alpha) binding to heparin. J Biol Chem (2007) 1.58
Alteration of enzyme specificity by computational loop remodeling and design. Proc Natl Acad Sci U S A (2009) 1.56
Local RNA structural changes induced by crystallization are revealed by SHAPE. RNA (2007) 1.55
Crystal structure of the multifunctional Gbeta5-RGS9 complex. Nat Struct Mol Biol (2008) 1.52
A seven-helix coiled coil. Proc Natl Acad Sci U S A (2006) 1.48
Structure and kinetics of monofunctional proline dehydrogenase from Thermus thermophilus. J Biol Chem (2007) 1.44
Nuclear Protein-Only Ribonuclease P2 Structure and Biochemical Characterization Provide Insight into the Conserved Properties of tRNA 5' End Processing Enzymes. J Mol Biol (2015) 1.42
Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin pUL26N, a Herpesvirus Serine Protease. PLoS Pathog (2015) 1.41
The IsdG-family of haem oxygenases degrades haem to a novel chromophore. Mol Microbiol (2010) 1.40
Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing. Nat Chem Biol (2009) 1.39
Structure of human monoamine oxidase A at 2.2-A resolution: the control of opening the entry for substrates/inhibitors. Proc Natl Acad Sci U S A (2008) 1.39
Assessment of automatic ligand building in ARP/wARP. Acta Crystallogr D Biol Crystallogr (2006) 1.38
Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxin. Nat Chem Biol (2009) 1.36
Crystal structure and computational characterization of the lytic polysaccharide monooxygenase GH61D from the Basidiomycota fungus Phanerochaete chrysosporium. J Biol Chem (2013) 1.34
The origin of the electrostatic perturbation in acetoacetate decarboxylase. Nature (2009) 1.34
Teaching an old scaffold new tricks: monobodies constructed using alternative surfaces of the FN3 scaffold. J Mol Biol (2011) 1.29
Structure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assembly. Cell (2011) 1.29
Atomic resolution structures of resting-state, substrate- and product-complexed Cu-nitrite reductase provide insight into catalytic mechanism. Proc Natl Acad Sci U S A (2005) 1.28
X-ray crystal structure of voltage-gated proton channel. Nat Struct Mol Biol (2014) 1.28
Graphical tools for macromolecular crystallography in PHENIX. J Appl Crystallogr (2012) 1.28
Four generations of transition-state analogues for human purine nucleoside phosphorylase. Proc Natl Acad Sci U S A (2010) 1.28
Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation. Hum Mol Genet (2009) 1.27
Structures of cyanobacteriochromes from phototaxis regulators AnPixJ and TePixJ reveal general and specific photoconversion mechanism. Proc Natl Acad Sci U S A (2012) 1.27
Inhibition of Nipah virus infection in vivo: targeting an early stage of paramyxovirus fusion activation during viral entry. PLoS Pathog (2010) 1.25
Conformational changes of glucose/galactose-binding protein illuminated by open, unliganded, and ultra-high-resolution ligand-bound structures. Protein Sci (2007) 1.24
Structure of the absent in melanoma 2 (AIM2) pyrin domain provides insights into the mechanisms of AIM2 autoinhibition and inflammasome assembly. J Biol Chem (2013) 1.24
Biochemical and structural characterization of Mycobacterium tuberculosis beta-lactamase with the carbapenems ertapenem and doripenem. Biochemistry (2010) 1.23
Coiled coils at the edge of configurational heterogeneity. Structural analyses of parallel and antiparallel homotetrameric coiled coils reveal configurational sensitivity to a single solvent-exposed amino acid substitution. Biochemistry (2006) 1.21
Divergence of multimodular polyketide synthases revealed by a didomain structure. Nat Chem Biol (2012) 1.20
Structure of the HIV-1 gp41 membrane-proximal ectodomain region in a putative prefusion conformation. Biochemistry (2009) 1.20
Structure of the vesicular stomatitis virus N⁰-P complex. PLoS Pathog (2011) 1.20
Auto-activation mechanism of the Mycobacterium tuberculosis PknB receptor Ser/Thr kinase. EMBO J (2008) 1.19
Conformation-independent structural comparison of macromolecules with ProSMART. Acta Crystallogr D Biol Crystallogr (2014) 1.19
Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases. PLoS Biol (2010) 1.18
Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit. Biochem J (2010) 1.18
The pK(a) values of acidic and basic residues buried at the same internal location in a protein are governed by different factors. J Mol Biol (2009) 1.17
Conformational exchange in a membrane transport protein is altered in protein crystals. Biophys J (2010) 1.17
Nuclear extracellular signal-regulated kinase 1 and 2 translocation is mediated by casein kinase 2 and accelerated by autophosphorylation. Mol Cell Biol (2011) 1.17
Crystal structure of the PAC1R extracellular domain unifies a consensus fold for hormone recognition by class B G-protein coupled receptors. PLoS One (2011) 1.16
Autoreactivity and exceptional CDR plasticity (but not unusual polyspecificity) hinder elicitation of the anti-HIV antibody 4E10. PLoS Pathog (2013) 1.16
A structural model for binding of the serine-rich repeat adhesin GspB to host carbohydrate receptors. PLoS Pathog (2011) 1.15
The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases. Nucleic Acids Res (2012) 1.15
RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA. J Exp Med (2013) 1.15
Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation. Nat Struct Mol Biol (2012) 1.15
Discovery of inhibitors of Escherichia coli methionine aminopeptidase with the Fe(II)-form selectivity and antibacterial activity. J Med Chem (2008) 1.14
Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine. J Biol Chem (2009) 1.13
High-resolution x-ray structure and functional analysis of the murine norovirus 1 capsid protein protruding domain. J Virol (2010) 1.13
A model of the membrane-bound cytochrome b5-cytochrome P450 complex from NMR and mutagenesis data. J Biol Chem (2013) 1.12
The X-ray crystal structure of human aminopeptidase N reveals a novel dimer and the basis for peptide processing. J Biol Chem (2012) 1.12
Identical phosphatase mechanisms achieved through distinct modes of binding phosphoprotein substrate. Proc Natl Acad Sci U S A (2010) 1.11
Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase. Proc Natl Acad Sci U S A (2009) 1.11
Molecular insight into bacterial cleavage of oceanic dimethylsulfoniopropionate into dimethyl sulfide. Proc Natl Acad Sci U S A (2014) 1.10
Plasmodium falciparum parasites are killed by a transition state analogue of purine nucleoside phosphorylase in a primate animal model. PLoS One (2011) 1.10
Crystal structure of 12-lipoxygenase catalytic-domain-inhibitor complex identifies a substrate-binding channel for catalysis. Structure (2012) 1.10
Insights into the reaction of protein-tyrosine phosphatase 1B: crystal structures for transition state analogs of both catalytic steps. J Biol Chem (2010) 1.10
The subtilisin-like protease AprV2 is required for virulence and uses a novel disulphide-tethered exosite to bind substrates. PLoS Pathog (2010) 1.10
Crystal structure of γ-tubulin complex protein GCP4 provides insight into microtubule nucleation. Nat Struct Mol Biol (2011) 1.10
Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation. BMC Struct Biol (2007) 1.09
Structure of Streptococcus agalactiae serine/threonine phosphatase. The subdomain conformation is coupled to the binding of a third metal ion. FEBS J (2007) 1.09
Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin. Biochemistry (2005) 1.09
PagP crystallized from SDS/cosolvent reveals the route for phospholipid access to the hydrocarbon ruler. Structure (2010) 1.09
Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases. Proc Natl Acad Sci U S A (2010) 1.09
Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir. J Mol Biol (2008) 1.09
Structural basis for the recognition of Lewis antigens by genogroup I norovirus. J Virol (2012) 1.09
A unique conformation of the anticodon stem-loop is associated with the capacity of tRNAfMet to initiate protein synthesis. Nucleic Acids Res (2008) 1.08
Structural basis for telomerase RNA recognition and RNP assembly by the holoenzyme La family protein p65. Mol Cell (2012) 1.06
(NZ)CH...O contacts assist crystallization of a ParB-like nuclease. BMC Struct Biol (2007) 1.06
Allosteric mechanism of pyruvate kinase from Leishmania mexicana uses a rock and lock model. J Biol Chem (2010) 1.06
The peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J Immunol (2012) 1.05
The 1.6 Å crystal structure of pyranose dehydrogenase from Agaricus meleagris rationalizes substrate specificity and reveals a flavin intermediate. PLoS One (2013) 1.05
Identification of the bile salt binding site on IpaD from Shigella flexneri and the influence of ligand binding on IpaD structure. Proteins (2012) 1.05
Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1. J Mol Biol (2008) 1.05
A conformational intermediate in glutamate receptor activation. Neuron (2013) 1.05
Structure of complement C6 suggests a mechanism for initiation and unidirectional, sequential assembly of membrane attack complex (MAC). J Biol Chem (2012) 1.04
The structure of interleukin-23 reveals the molecular basis of p40 subunit sharing with interleukin-12. J Mol Biol (2008) 1.04
Jolly SAD. Acta Crystallogr D Biol Crystallogr (2002) 1.96
Dental extractions prior to radiotherapy to the jaws for reducing post-radiotherapy dental complications. Cochrane Database Syst Rev (2013) 1.07
Multicenter phase 2 trial of thalidomide in relapsed/refractory multiple myeloma: adverse prognostic impact of advanced age. Blood (2003) 0.93
Fire in Australian savannas: from leaf to landscape. Glob Chang Biol (2014) 0.92
Crystal structure of an intracellular subtilisin reveals novel structural features unique to this subtilisin family. Structure (2010) 0.84
Demolition experts: management of the parafunctional patient: 1. Diagnosis and prevention. Dent Update (2007) 0.79
The Australian Cancer Anaemia Survey: a snapshot of anaemia in adult patients with cancer. Med J Aust (2005) 0.79
Crystallization and X-ray structure analysis of a thermostable penicillin G acylase from Alcaligenes faecalis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.79
British Society of Prosthodontics Debate on the Implications of the Minamata Convention on Mercury to Dental Amalgam--Should our Patients be Worried?. Dent Update (2016) 0.76
Technique tips--Non-surgical management of deep periodontal pockets--avoid the scalpel! Dent Update (2013) 0.75
An amalgam-free world--are we and our patients ready? Dent Update (2016) 0.75
Technique tips--the importance of a bitewing radiograph in the endodontic assessment of posterior teeth. Dent Update (2014) 0.75
Demolition experts: management of the parafunctional patient: 2. Restorative management strategies. Dent Update (2007) 0.75