Published in Cancer Res on July 01, 2003
Expression and functional role of a transcribed noncoding RNA with an ultraconserved element in hepatocellular carcinoma. Proc Natl Acad Sci U S A (2010) 1.87
MiR-107 and MiR-185 can induce cell cycle arrest in human non small cell lung cancer cell lines. PLoS One (2009) 1.70
Fibroblast growth factor 19 expression correlates with tumor progression and poorer prognosis of hepatocellular carcinoma. BMC Cancer (2012) 1.19
Characterization of nuclear localization signal in the N terminus of CUL4B and its essential role in cyclin E degradation and cell cycle progression. J Biol Chem (2009) 1.12
Cell-specific delivery of diverse cargos by bacteriophage MS2 virus-like particles. ACS Nano (2011) 1.09
siRNA-based targeting of cyclin E overexpression inhibits breast cancer cell growth and suppresses tumor development in breast cancer mouse model. PLoS One (2010) 1.00
RNA interference-mediated silencing of the polo-like kinase 1 gene enhances chemosensitivity to gemcitabine in pancreatic adenocarcinoma cells. J Cell Mol Med (2008) 0.90
Targeting cancer gene therapy with magnetic nanoparticles. Oncotarget (2012) 0.87
The hypofunctional effect of P335L single nucleotide polymorphism on SSTR5 function. World J Surg (2011) 0.87
Down-regulation of Bcl-XL by RNA interference suppresses cell growth and induces apoptosis in human esophageal cancer cells. World J Gastroenterol (2006) 0.87
L1 retrotransposon-mediated stable gene silencing. Nucleic Acids Res (2005) 0.83
Silencing Fas-associated phosphatase 1 expression enhances efficiency of chemotherapy for colon carcinoma with oxaliplatin. World J Gastroenterol (2010) 0.83
Personalized cancer approach: using RNA interference technology. World J Surg (2011) 0.83
The Complex Relationship between Liver Cancer and the Cell Cycle: A Story of Multiple Regulations. Cancers (Basel) (2014) 0.82
Intensified antineoplastic effect by combining an HDAC-inhibitor, an mTOR-inhibitor and low dosed interferon alpha in prostate cancer cells. J Cell Mol Med (2015) 0.79
Nanoparticles for targeted delivery of therapeutics and small interfering RNAs in hepatocellular carcinoma. World J Gastroenterol (2015) 0.79
Pfaffosidic Fraction from Hebanthe paniculata Induces Cell Cycle Arrest and Caspase-3-Induced Apoptosis in HepG2 Cells. Evid Based Complement Alternat Med (2015) 0.77
From big data to diagnosis and prognosis: gene expression signatures in liver hepatocellular carcinoma. PeerJ (2017) 0.75
Survivin downregulation using siRNA nanoliposomes inhibits cell proliferation and promotes the apoptosis of MHCC-97H hepatic cancer cells: An in vitro and in vivo study. Oncol Lett (2017) 0.75
Downregulation of Kinesin spindle protein inhibits proliferation, induces apoptosis and increases chemosensitivity in hepatocellular carcinoma cells. Iran Biomed J (2015) 0.75
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature (2012) 8.31
PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling. Cell (2006) 5.28
BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer. Cancer Cell (2006) 2.61
beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer. Cancer Cell (2002) 2.33
BRIT1/MCPH1 links chromatin remodelling to DNA damage response. Nat Cell Biol (2009) 2.06
Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer. Mol Cancer Ther (2008) 1.90
SUMO-1/Ubc9 promotes nuclear accumulation and metabolic stability of tumor suppressor Smad4. J Biol Chem (2003) 1.82
Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression. Proc Natl Acad Sci U S A (2007) 1.81
Nucleostemin deletion reveals an essential mechanism that maintains the genomic stability of stem and progenitor cells. Proc Natl Acad Sci U S A (2013) 1.65
Opposed regulation of corepressor CtBP by SUMOylation and PDZ binding. Mol Cell (2003) 1.57
TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs. Nat Struct Mol Biol (2009) 1.51
Rak functions as a tumor suppressor by regulating PTEN protein stability and function. Cancer Cell (2009) 1.48
A retrovirus-based protein complementation assay screen reveals functional AKT1-binding partners. Proc Natl Acad Sci U S A (2006) 1.36
Activation of transforming growth factor-beta signaling by SUMO-1 modification of tumor suppressor Smad4/DPC4. J Biol Chem (2003) 1.32
Elevated portal vein drug levels of sirolimus and tacrolimus in islet transplant recipients: local immunosuppression or islet toxicity? Transplantation (2003) 1.32
Islet vasculature as a regulator of endocrine pancreas function. World J Surg (2007) 1.31
Down-regulation of ZIP4 by RNA interference inhibits pancreatic cancer growth and increases the survival of nude mice with pancreatic cancer xenografts. Clin Cancer Res (2009) 1.30
Monoubiquitination of H2AX protein regulates DNA damage response signaling. J Biol Chem (2011) 1.29
Pancreatic carcinoma cells express neuropilins and vascular endothelial growth factor, but not vascular endothelial growth factor receptors. Cancer (2004) 1.22
General surgery as a career: a contemporary review of factors central to medical student specialty choice. J Am Coll Surg (2004) 1.22
FOXM1 mediates Dox resistance in breast cancer by enhancing DNA repair. Carcinogenesis (2012) 1.22
Polymer nanofiber-embedded microchips for detection, isolation, and molecular analysis of single circulating melanoma cells. Angew Chem Int Ed Engl (2013) 1.21
Laparoscopic colon resection early in the learning curve: what is the appropriate setting? Ann Surg (2006) 1.19
BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice. PLoS Genet (2010) 1.18
PDX-1 acts as a potential molecular target for treatment of human pancreatic cancer. Pancreas (2008) 1.17
Phase I trial of "bi-shRNAi(furin)/GMCSF DNA/autologous tumor cell" vaccine (FANG) in advanced cancer. Mol Ther (2011) 1.15
Differential regulation of centrosome integrity by DNA damage response proteins. Cell Cycle (2008) 1.14
Smad6 recruits transcription corepressor CtBP to repress bone morphogenetic protein-induced transcription. Mol Cell Biol (2003) 1.13
Impact of three-dimensional vision in laparoscopic training. World J Surg (2008) 1.12
PDX-1 and the pancreas. Pancreas (2004) 1.11
dSmurf selectively degrades decapentaplegic-activated MAD, and its overexpression disrupts imaginal disc development. J Biol Chem (2003) 1.10
Human nuclease/helicase DNA2 alleviates replication stress by promoting DNA end resection. Cancer Res (2012) 1.10
Physician leadership is a new mandate in surgical training. Am J Surg (2004) 1.10
IL-6 stimulates Th2 type cytokine secretion and upregulates VEGF and NRP-1 expression in pancreatic cancer cells. Cancer Biol Ther (2007) 1.08
PPM1A Functions as a Smad Phosphatase to Terminate TGFβ Signaling. Cell (2016) 1.07
Achievement of insulin independence in three consecutive type-1 diabetic patients via pancreatic islet transplantation using islets isolated at a remote islet isolation center. Transplantation (2002) 1.06
Value of pancreatic resection for cancer metastatic to the pancreas. J Surg Res (2009) 1.06
DNA damage response pathways in tumor suppression and cancer treatment. World J Surg (2009) 1.05
Pancreatic polypeptide administration reduces insulin requirements of artificial pancreas in pancreatectomized dogs. Artif Organs (2005) 1.05
Pancreatic resection without routine intraperitoneal drainage. HPB (Oxford) (2011) 1.04
Accuracy of CT in predicting malignant potential of cystic pancreatic neoplasms. HPB (Oxford) (2008) 1.03
Current progress in suicide gene therapy for cancer. World J Surg (2002) 1.02
Interleukin-8 increases vascular endothelial growth factor and neuropilin expression and stimulates ERK activation in human pancreatic cancer. Cancer Sci (2008) 1.02
siRNA-based targeting of cyclin E overexpression inhibits breast cancer cell growth and suppresses tumor development in breast cancer mouse model. PLoS One (2010) 1.00
Percutaneous cholecystostomy for acute cholecystitis in high-risk patients: experience of a surgeon-initiated interventional program. Am J Surg (2007) 0.98
Tissue MicroArray analyses of pancreatic duodenal homeobox-1 in human cancers. World J Surg (2005) 0.98
Ubiquitination and proteolysis of cancer-derived Smad4 mutants by SCFSkp2. Mol Cell Biol (2004) 0.98
Procurement of the human pancreas for pancreatic islet transplantation. Transplantation (2004) 0.98
DNA damage response is suppressed by the high cyclin-dependent kinase 1 activity in mitotic mammalian cells. J Biol Chem (2011) 0.97
BRIT1/MCPH1: a guardian of genome and an enemy of tumors. Cell Cycle (2006) 0.97
Smad3 mediates immediate early induction of Id1 by TGF-beta. Cell Res (2009) 0.97
The natural resistance-associated macrophage protein 1 Slc11a1 (formerly Nramp1) and iron metabolism in macrophages. Microbes Infect (2002) 0.97
Effect of BioGlue on the incidence of pancreatic fistula following pancreas resection. J Gastrointest Surg (2008) 0.97
A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth. EMBO Mol Med (2013) 0.96
Cell-specific cytotoxicity of human pancreatic adenocarcinoma cells using rat insulin promoter thymidine kinase-directed gene therapy. World J Surg (2004) 0.96
Basic principles and technologies for deciphering the genetic map of cancer. World J Surg (2009) 0.96
Drain data to predict clinically relevant pancreatic fistula. HPB (Oxford) (2010) 0.95
PDX-1 expression is associated with islet proliferation in vitro and in vivo. J Surg Res (2007) 0.95
PDX-1: demonstration of oncogenic properties in pancreatic cancer. Cancer (2010) 0.94
Chromodomain helicase DNA-binding protein 4 (CHD4) regulates homologous recombination DNA repair, and its deficiency sensitizes cells to poly(ADP-ribose) polymerase (PARP) inhibitor treatment. J Biol Chem (2012) 0.94
The impact of a novel resident leadership training curriculum. Am J Surg (2004) 0.93
Value of pancreatic resection for cancer metastatic to the pancreas. J Surg Res (2010) 0.91
Health-related quality of life after pancreatic islet transplantation: a longitudinal study. Transplantation (2005) 0.91
Pancreatic islet transplantation: the radiographic approach. Transplantation (2003) 0.90
Transgastric endoscopic rendezvous technique for removal of eroded Molina gastric band. Surg Obes Relat Dis (2008) 0.90
Concomitant intraoperative splenic artery embolization and laparoscopic splenectomy versus laparoscopic splenectomy: comparison of treatment outcome. Am J Surg (2007) 0.89
DNA damage response: the players, the network and the role in tumor suppression. Cancer Genomics Proteomics (2007) 0.89
Disruption of the Nramp1 (also known as Slc11a1) gene in Kupffer cells attenuates early-phase, warm ischemia-reperfusion injury in the mouse liver. J Leukoc Biol (2002) 0.89
Somatostatin receptor-1 induces cell cycle arrest and inhibits tumor growth in pancreatic cancer. Cancer Sci (2008) 0.89
BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade. Proc Natl Acad Sci U S A (2013) 0.88
PDX-1 is a therapeutic target for pancreatic cancer, insulinoma and islet neoplasia using a novel RNA interference platform. PLoS One (2012) 0.88
The hypofunctional effect of P335L single nucleotide polymorphism on SSTR5 function. World J Surg (2011) 0.87
Rectal duplication cyst in an adult: the laparoscopic approach. J Laparoendosc Adv Surg Tech A (2002) 0.87
Conflict resolution: practical principles for surgeons. World J Surg (2008) 0.86
Transaminitis after pancreatic islet transplantation. J Am Coll Surg (2005) 0.86
ZNF668 functions as a tumor suppressor by regulating p53 stability and function in breast cancer. Cancer Res (2011) 0.86
Developing a tissue resource to characterize the genome of pancreatic cancer. World J Surg (2009) 0.86
Effective ablation of pancreatic cancer cells in SCID mice using systemic adenoviral RIP-TK/GCV gene therapy. J Surg Res (2007) 0.85
DNA damage and breast cancer. World J Clin Oncol (2011) 0.85
Routine nasogastric suction may be unnecessary after a pancreatic resection. HPB (Oxford) (2011) 0.84
Dual functions of the homeoprotein DLX4 in modulating responsiveness of tumor cells to topoisomerase II-targeting drugs. Cancer Res (2012) 0.84
Development of a human pancreatic islet-transplant program through a collaborative relationship with a remote islet-isolation center. Transplantation (2004) 0.84
BRIT1/MCPH1 is a multifunctional DNA damage responsive protein mediating DNA repair-associated chromatin remodeling. Cell Cycle (2009) 0.83
Enhanced cytotoxicity of RIPTK gene therapy of pancreatic cancer via PDX-1 co-delivery. J Surg Res (2007) 0.83
Single nucleotide polymorphism in RECQL and survival in resectable pancreatic adenocarcinoma. HPB (Oxford) (2009) 0.83
Deregulation of iron homeostasis and cold-preservation injury to rat liver stored in University of Wisconsin solution. Liver Transpl (2003) 0.83
Multiple treatment cycles of liposome-encapsulated adenoviral RIP-TK gene therapy effectively ablate human pancreatic cancer cells in SCID mice. Surgery (2011) 0.83
Personalized cancer approach: using RNA interference technology. World J Surg (2011) 0.83
Zinc finger protein 668 interacts with Tip60 to promote H2AX acetylation after DNA damage. Cell Cycle (2013) 0.83
Serum response factor expression is enriched in pancreatic β cells and regulates insulin gene expression. FASEB J (2011) 0.83
Specific gene expression and therapy for pancreatic cancer using the cytosine deaminase gene directed by the rat insulin promoter. J Gastrointest Surg (2004) 0.83
Exploring Rak tyrosine kinase function in breast cancer. Cell Cycle (2009) 0.82
Specific targeting of pancreatic islet cells in vivo by insulin-promoter-driven adenoviral conjugated reporter genes. World J Surg (2006) 0.82
Exploiting the homologous recombination DNA repair network for targeted cancer therapy. World J Clin Oncol (2011) 0.82
Intravenous Cidofovir therapy for disseminated adenovirus in a pediatric liver transplant recipient. Transplantation (2002) 0.82
Somatostatin and its receptors in the development of the endocrine pancreas. Pancreas (2006) 0.81
Molecular targeting of pancreatic disorders. World J Surg (2005) 0.81
Association between somatostatin receptor 5 gene polymorphisms and pancreatic cancer risk and survival. Cancer (2011) 0.81